RT Journal Article
SR Electronic
T1 Outcome Measures in Polymyalgia Rheumatica. A Systematic Review
JF The Journal of Rheumatology
JO J Rheumatol
FD The Journal of Rheumatology
SP 2503
OP 2511
DO 10.3899/jrheum.150515
VO 42
IS 12
A1 Duarte, Cátia
A1 Ferreira, Ricardo Jorge de Oliveira
A1 Mackie, Sarah Louise
A1 Kirwan, John Richard
A1 Pereira da Silva, José António
A1 The OMERACT Polymyalgia Rheumatica Special Interest Group
YR 2015
UL http://www.jrheum.org/content/42/12/2503.abstract
AB Objective. To identify the instruments used to assess polymyalgia rheumatica (PMR) in published studies.Methods. A systematic literature review of clinical trials and longitudinal observational studies related to PMR, published from 1970 to 2014, was carried out. All outcome and assessment instruments were extracted and categorized according to core areas and domains, as defined by the OMERACT (Outcome Measures in Rheumatology) Filter 2.0.Results. Thirty-five articles (3221 patients) were included: 12 randomized controlled trials (RCT); 3 nonrandomized trials; and 20 observational studies. More than 20 domains were identified, measured by 29 different instruments. The most frequently used measures were pain, morning stiffness, patient global assessment and physician global assessment, erythrocyte sedimentation rate, and C-reactive protein. The definition of outcomes varied considerably between studies.Conclusion. The outcome measures and instruments used in PMR are numerous and diversely defined. The establishment of a core set of validated and standardized outcome measurements is needed.