RT Journal Article
SR Electronic
T1 Current State of Reporting Pain Outcomes in Cochrane Reviews of Chronic Musculoskeletal Pain Conditions and Considerations for an OMERACT Research Agenda
JF The Journal of Rheumatology
JO J Rheumatol
FD The Journal of Rheumatology
SP 1934
OP 1942
DO 10.3899/jrheum.141423
VO 42
IS 10
A1 Maxwell, Lara J.
A1 Wells, George A.
A1 Simon, Lee S.
A1 Conaghan, Philip G.
A1 Grosskleg, Shawna
A1 Scrivens, Kerry
A1 Beaton, Dorcas E.
A1 Bingham, Clifton O.
A1 Busse, Jason W.
A1 Christensen, Robin
A1 Goel, Niti
A1 Jüni, Peter
A1 Kaiser, Ulrike
A1 Lyddiatt, Anne
A1 Mease, Philip J.
A1 Ostelo, Raymond W.
A1 Phillips, Kristine
A1 Sapunar, Damir
A1 Singh, Jasvinder A.
A1 Strand, Vibeke
A1 Taylor, Ann M.
A1 Terwee, Caroline B.
A1 Tugwell, Peter
YR 2015
UL http://www.jrheum.org/content/42/10/1934.abstract
AB Objective. To assess the current state of reporting of pain outcomes in Cochrane reviews on chronic musculoskeletal painful conditions and to elicit opinions of patients, healthcare practitioners, and methodologists on presenting pain outcomes to patients, clinicians, and policymakers.Methods. We identified all reviews in the Cochrane Library of chronic musculoskeletal pain conditions from Cochrane review groups (Back, Musculoskeletal, and Pain, Palliative, and Supportive Care) that contained a summary of findings (SoF) table. We extracted data on reported pain domains and instruments and conducted a survey and interviews on considerations for SoF tables (e.g., pain domains, presentation of results).Results. Fifty-seven SoF tables in 133 Cochrane reviews were eligible. SoF tables reported pain in 56/57, with all presenting results for pain intensity (20 different outcome instruments), pain interference in 8 SoF tables (5 different outcome instruments), and pain frequency in 1 multiple domain instrument. Other domains like pain quality or pain affect were not reported. From the survey and interviews [response rate 80% (36/45)], we derived 4 themes for a future research agenda: pain domains, considerations for assessing truth, discrimination, and feasibility; clinically important thresholds for responder analyses and presenting results; and establishing hierarchies of outcome instruments.Conclusion. There is a lack of standardization in the domains of pain selected and the manner that pain outcomes are reported in SoF tables, hampering efforts to synthesize evidence. Future research should focus on the themes identified, building partnerships to achieve consensus and develop guidance on best practices for reporting pain outcomes.