RT Journal Article SR Electronic T1 Comprehensive Treatment of Psoriatic Arthritis: Managing Comorbidities and Extraarticular Manifestations JF The Journal of Rheumatology JO J Rheumatol FD The Journal of Rheumatology SP 2315 OP 2322 DO 10.3899/jrheum.140882 VO 41 IS 11 A1 Alexis Ogdie A1 Sergio Schwartzman A1 Lihi Eder A1 Ajesh B. Maharaj A1 Devy Zisman A1 Siba P. Raychaudhuri A1 Soumya M. Reddy A1 Elaine Husni YR 2014 UL http://www.jrheum.org/content/41/11/2315.abstract AB Psoriatic arthritis (PsA) is an inflammatory arthritis associated with psoriasis that can lead to decreased health-related quality of life and permanent joint damage leading to functional decline. In addition to joint and skin manifestations, both psoriasis and PsA are associated with numerous comorbidities and extraarticular/cutaneous manifestations, which may influence the physician’s choice of therapy. The objectives of this review are (1) to identify comorbidities in patients with PsA based on the available evidence; (2) to examine the effects of these comorbidities or extraarticular/cutaneous manifestation on the management of patients with PsA as well as the selection of therapy; and (3) to highlight research needs around comorbidities and treatment paradigms. This review is part of a treatment recommendations update initiated by the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA).