RT Journal Article SR Electronic T1 Extraarticular Manifestations of Rheumatoid Arthritis Develop in Patients Receiving Anti-Tumor Necrosis Factor-α Treatment: A Retrospective Chart Review from a UK Center JF The Journal of Rheumatology JO J Rheumatol FD The Journal of Rheumatology SP 1944 OP 1947 DO 10.3899/jrheum.131026 VO 41 IS 10 A1 Andra Florina Negoescu A1 Dilrukshi Tennekone A1 Michael Anthony Soljak A1 Sonya Marie Abraham YR 2014 UL http://www.jrheum.org/content/41/10/1944.abstract AB Objective. To assess the evolution of preexisting extraarticular manifestations of rheumatoid arthritis (EA-RA) in patients treated with anti-tumor necrosis factor-α (TNF-α), as well as the development of new EA-RA. Methods. We assessed EA-RA in 152 patients receiving anti-TNF-α treatment. Results. In 22 cases, a new EA-RA developed. In 5 cases, there was evidence of progression of preexisting EA-RA. Regression was found in 4 cases. Some patients were in disease remission when they developed EA-RA, whereas some patients had moderate/high disease activity. Conclusion. EA-RA are still present in patients treated with anti-TNF-α. Development of new severe EA-RA is rare in patients receiving anti-TNF therapy.