PT - JOURNAL ARTICLE AU - Andra Florina Negoescu AU - Dilrukshi Tennekone AU - Michael Anthony Soljak AU - Sonya Marie Abraham TI - Extraarticular Manifestations of Rheumatoid Arthritis Develop in Patients Receiving Anti-Tumor Necrosis Factor-α Treatment: A Retrospective Chart Review from a UK Center AID - 10.3899/jrheum.131026 DP - 2014 Oct 01 TA - The Journal of Rheumatology PG - 1944--1947 VI - 41 IP - 10 4099 - http://www.jrheum.org/content/41/10/1944.short 4100 - http://www.jrheum.org/content/41/10/1944.full SO - J Rheumatol2014 Oct 01; 41 AB - Objective. To assess the evolution of preexisting extraarticular manifestations of rheumatoid arthritis (EA-RA) in patients treated with anti-tumor necrosis factor-α (TNF-α), as well as the development of new EA-RA. Methods. We assessed EA-RA in 152 patients receiving anti-TNF-α treatment. Results. In 22 cases, a new EA-RA developed. In 5 cases, there was evidence of progression of preexisting EA-RA. Regression was found in 4 cases. Some patients were in disease remission when they developed EA-RA, whereas some patients had moderate/high disease activity. Conclusion. EA-RA are still present in patients treated with anti-TNF-α. Development of new severe EA-RA is rare in patients receiving anti-TNF therapy.