PT  - JOURNAL ARTICLE
AU  - Brian C. Focht
AU  - Matthew J. Garver
AU  - Steven T. Devor
AU  - Justin Dials
AU  - Alexander R. Lucas
AU  - Charles F. Emery
AU  - Kevin V. Hackshaw
AU  - W. Jack Rejeski
TI  - Group-mediated Physical Activity Promotion and Mobility in Sedentary Patients with Knee Osteoarthritis: Results from the IMPACT-Pilot Trial
AID  - 10.3899/jrheum.140054
DP  - 2014 Oct 01
TA  - The Journal of Rheumatology
PG  - 2068--2077
VI  - 41
IP  - 10
4099  - http://www.jrheum.org/content/41/10/2068.short
4100  - http://www.jrheum.org/content/41/10/2068.full
SO  - J Rheumatol2014 Oct 01; 41
AB  - Objective. To compare the effects of a group-mediated cognitive behavioral exercise intervention (GMCB) with traditional center-based exercise therapy (TRAD) on objectively assessed levels of physical activity (PA) and mobility in sedentary patients with knee osteoarthritis (OA). Methods. The Improving Maintenance of Physical Activity in Knee Osteoarthritis Trial-Pilot (IMPACT-P) was a 12-month, 2-arm, single-blind, randomized controlled pilot study designed to compare the effects of GMCB and TRAD on 80 sedentary patients with knee OA with self-reported difficulty in daily activities [mean age 63.5 yrs, 84% women, mean body mass index (BMI) 32.7 kg/m2]. Objective assessments of PA (LIFECORDER Plus Accelerometer) and mobility (400-m walk) were obtained at baseline, 3 months, and 12 months by study personnel blinded to participants’ treatment assignment. Results. Intent to treat 2 (treatment: GMCB and TRAD) × 2 (time: 3 mos and 12 mos) analyses of covariance of controlling for baseline, age, sex, and BMI-adjusted change in the outcomes demonstrated that the GMCB intervention yielded significantly greater increases in PA (p < 0.01) and a nonsignificant yet more favorable improvement in mobility (p = 0.09) relative to TRAD. Partial correlation analyses also revealed that change in PA was significantly correlated with the 400-m walk performance at 3-month (r = −0.51, p < 0.01) and 12-month (r = −0.40, p < 0.01) followup assessments. Conclusion. Findings from the IMPACT-P trial suggest that the GMCB treatment resulted in significantly greater improvement in PA and nonsignificant yet more favorable change in mobility relative to TRAD.