RT Journal Article
SR Electronic
T1 The Microanatomic Basis of Finger Clubbing — A High-resolution Magnetic Resonance Imaging Study
JF The Journal of Rheumatology
JO J Rheumatol
FD The Journal of Rheumatology
SP 523
OP 527
DO 10.3899/jrheum.130823
VO 41
IS 3
A1 Junichi Nakamura
A1 Nicola Ann Halliday
A1 Eiji Fukuba
A1 Aleksandra Radjenovic
A1 Steven F. Tanner
A1 Paul Emery
A1 Dennis McGonagle
A1 Ai Lyn Tan
YR 2014
UL http://www.jrheum.org/content/41/3/523.abstract
AB Objective. Hypervascularization in finger clubbing is recognized, but its microanatomical basis remains unclear. This pilot descriptive study used magnetic resonance imaging (MRI) to explore this further. Methods. High-resolution MRI acquired with contrast agent was carried out in 4 patients with finger clubbing and 4 healthy volunteers. The anatomy of the nail bed, capsular structures, and bony changes were described. Results. Marked nail bed thickening and contrast enhancement was noted in all clubbed fingers, with bone edema in 3 of the 4 patients. None of the healthy subjects had similar abnormalities. Conclusion. This confirms that hypervascularization of the nail bed observed in the microanatomy on high-resolution MRI is associated with clubbed appearances of the nails.