TY - JOUR T1 - New Onset of Psoriasis in a Patient with Rheumatoid Arthritis Treated with Rituximab JF - The Journal of Rheumatology JO - J Rheumatol SP - 1230 LP - 1231 DO - 10.3899/jrheum.130050 VL - 40 IS - 7 AU - ÉRIC TOUSSIROT Y1 - 2013/07/01 UR - http://www.jrheum.org/content/40/7/1230.abstract N2 - To the Editor:We read with interest reports by Thomas, et al1 and by Hardcastle, et al2 reporting new onset of psoriasis during rituximab (RTX) therapy for rheumatoid arthritis (RA). We have observed an additional case in a patient who had received several biological agents prior to RTX.A 44-year-old white woman with a history of erosive peripheral and symmetrical polyarthritis with positive rheumatoid factors and anticyclic citrullinated peptide antibodies had been diagnosed as having RA. She was seen for the first time in 1998. She had no other relevant history, especially no personal or familial psoriasis. Her polyarthritis was successively treated with traditional disease-modifying antirheumatic agents [sulfasalazine, methotrexate (MTX)] in combination with corticosteroids (7.5 to 10 mg/day). Because of progression of structural damage on wrist and hand radiographs, she received tumor necrosis factor-α (TNF-α)-blocking agents (infliximab, followed by etanercept and lastly adalimumab) between 2002 and 2010, with initial clinical improvement followed by secondary loss of efficacy. These treatments were well tolerated without … Address correspondence to Prof. Toussirot; E-mail: etoussirot{at}chu-besancon.fr ER -