@article {Leegaard1212, author = {Anne Leegaard and Johanne Jeppesen Lomholt and Mikael Thastum and Troels Herlin}, title = {Decreased Pain Threshold in Juvenile Idiopathic Arthritis: A Cross-sectional Study}, volume = {40}, number = {7}, pages = {1212--1217}, year = {2013}, doi = {10.3899/jrheum.120793}, publisher = {The Journal of Rheumatology}, abstract = {Objective. To examine the pain threshold in children with juvenile idiopathic arthritis (JIA) compared with healthy children by using a digital pressure algometer. Methods. Fifty-eight children with JIA born between 1995 and 2000 and 91 age-related healthy children participated in the study. We used a digital pressure algometer to measure the pain threshold on 17 symmetric, anatomically predefined joint-related or bone-related areas. All children were asked to rate their current pain on a Faces Pain Scale, and parents of children with JIA were asked to complete a parental revised version of the Child Health Assessment Questionnaire (CHAQ-R). Clinical data were registered on children with JIA. Results. The pain threshold was significantly lower among children with JIA (total mean PT = 1.33 {\textpm} 0.69 kg/cm2) when compared with the healthy control group (total mean PT = 1.77 {\textpm} 0.67 kg/cm2). The same pattern was found in all areas measured, including negative control areas that are normally unaffected in JIA (p = 0.0001 to 0.005). Overall, the pain threshold was 34\% lower in females than in males in both groups (p \< 0.0001). We found no correlation between pain threshold and age, current pain experience, disease duration, or disease activity. Conclusion. Children with JIA had a substantially lower pain threshold even in areas usually unaffected by arthritis. Our findings suggest that JIA alters the pain perception and causes decreased pain threshold.}, issn = {0315-162X}, URL = {https://www.jrheum.org/content/40/7/1212}, eprint = {https://www.jrheum.org/content/40/7/1212.full.pdf}, journal = {The Journal of Rheumatology} }