TY - JOUR T1 - Interleukin 22, a Potential Therapeutic Target for Rheumatoid Arthritis JF - The Journal of Rheumatology JO - J Rheumatol SP - 2220 LP - 2221 DO - 10.3899/jrheum.120757 VL - 39 IS - 11 AU - QIANG XIE AU - SHI-CUN WANG AU - JUN LI Y1 - 2012/11/01 UR - http://www.jrheum.org/content/39/11/2220.abstract N2 - To the Editor:A recent report by Da Rocha, et al indicated that levels of interleukin 22 (IL-22) were increased in patients with rheumatoid arthritis (RA) compared with controls; levels of IL-22 correlated with Disease Activity Score (DAS28) and Clinical Disease Activity Index measures, rheumatoid factor positivity was correlated with higher levels of IL-22 in patients with RA, and the presence of bone erosions was associated with high IL-22 levels1. These findings suggest that IL-22 may be a good biomarker for assessment of activity in RA, and IL-22 seems to be a potential therapeutic target for RA.Other studies have indicated the similar relationship between IL-22 and RA, … Address correspondence to Dr. Li; E-mail: lijun{at}ahmu.edu.cn ER -