RT Journal Article
SR Electronic
T1 Identification of the Clinical Features Distinguishing Psoriatic Arthritis and Fibromyalgia
JF The Journal of Rheumatology
JO J Rheumatol
FD The Journal of Rheumatology
SP 849
OP 855
DO 10.3899/jrheum.110893
VO 39
IS 4
A1 MARCHESONI, ANTONIO
A1 ATZENI, FABIOLA
A1 SPADARO, ANTONIO
A1 LUBRANO, ENNIO
A1 PROVENZANO, GIUSEPPE
A1 CAULI, ALBERTO
A1 OLIVIERI, IGNAZIO
A1 MELCHIORRE, DANIELA
A1 SALVARANI, CARLO
A1 SCARPA, RAFFAELE
A1 SARZI-PUTTINI, PIERCARLO
A1 MONTEPAONE, MONICA
A1 PORRU, GIOVANNI
A1 D’ANGELO, SALVATORE
A1 CATANOSO, MARIAGRAZIA
A1 COSTA, LUISA
A1 MANARA, MARIA
A1 VARISCO, VALENTINA
A1 ROTUNNO, LAURA
A1 DE LUCIA, ORAZIO
A1 DE MARCO, GABRIELE
YR 2012
UL http://www.jrheum.org/content/39/4/849.abstract
AB Objective. To identify the clinical features that can help to distinguish between psoriatic arthritis (PsA) and fibromyalgia (FM). Methods. Our cross-sectional study was carried out in 10 Italian rheumatology centers between January and September 2009, and enrolled all consecutive patients with PsA and FM who agreed to participate. Standard clinical and laboratory data for PsA and FM were collected from all patients. Records were made of somatic symptoms, response to nonsteroidal antiinflammatory drugs (NSAID), self-evaluated pain, general health, disability, and responses to the Fibromyalgia Impact Questionnaire. Data were statistically analyzed by univariate and multivariate analyses, and receiver-operating characteristic curves. The analysis concentrated on the clinical features shared by the 2 conditions. Results. Two hundred sixty-six patients with PsA (mean age 51.7 yrs; disease duration 10.2 yrs) and 120 patients with FM (mean age 50.2 yrs; disease duration 5.6 yrs) were evaluated. Univariate analysis showed that patients with FM had higher mean tender point and enthesitis scores, more somatic symptoms, and responded less to NSAID. Multivariate analysis showed that the presence of ≥ 6 FM-associated symptoms and ≥ 8 tender points was the best predictor of FM. Conclusion. The shared clinical features of PsA and FM that had the greatest discriminating power for FM were the number of FM-associated symptoms and tender point count.