TY - JOUR T1 - Nail Disease in Psoriatic Arthritis: Distal Phalangeal Bone Edema Detected by Magnetic Resonance Imaging Predicts Development of Onycholysis and Hyperkeratosis JF - The Journal of Rheumatology JO - J Rheumatol SP - 841 LP - 843 DO - 10.3899/jrheum.111118 VL - 39 IS - 4 AU - NICOLA DALBETH AU - KAREN PUI AU - MARIA LOBO AU - ANTHONY DOYLE AU - PETER B. JONES AU - WILLIAM J. TAYLOR AU - FIONA M. McQUEEN Y1 - 2012/04/01 UR - http://www.jrheum.org/content/39/4/841.abstract N2 - Objective. To examine the association between magnetic resonance imaging (MRI) features of distal phalanx (DP) disease and the progression of nail pathology in psoriatic arthritis (PsA). Methods. Clinical nail assessment and hand MRI scans were done on 34 patients with PsA. Twenty patients had repeat nail assessments after 1 year. Results. Nails with onycholysis and hyperkeratosis at baseline were more likely to have corresponding DP bone erosion and proliferation on MRI. DP bone edema on baseline MRI was associated with development of onycholysis and hyperkeratosis in corresponding nails. Conclusion. Our data suggest that DP inflammation is central in the development of psoriatic nail disease. ER -