TY - JOUR T1 - Pyoderma Gangrenosum in a Patient with Systemic Sclerosis JF - The Journal of Rheumatology JO - J Rheumatol SP - 197 LP - 197 DO - 10.3899/jrheum.110479 VL - 39 IS - 1 AU - JOY FELD AU - REUVEN BERGMAN AU - SARA WELTFRIEND AU - DEVY ZISMAN Y1 - 2012/01/01 UR - http://www.jrheum.org/content/39/1/197.abstract N2 - To the Editor:Pyoderma gangrenosum (PG) is an ulcerative inflammatory noninfectious disease of the skin. Treatment is mainly empirical, consisting of a combination of local and systemic treatments, including corticosteroids and immunosuppressive drugs1.In many cases, PG is associated with an underlying disease, most commonly inflammatory bowel disease, occasionally in the stromal area. PG occurs in several hematological and malignant diseases. PG has also been described in several rheumatic diseases: rheumatoid arthritis, spondyloarthropathies, systemic lupus erythematosus, Behçet’s disease, and sarcoidosis2. Hod, et al3 reported a huge PG-like lesion as a presenting sign of antiphospholipid antibody syndrome (APS). In the literature we are aware of … Address correspondence to Dr. J. Feld, Bnai Zion Medical Center – Rheumatology, 47 Golomb Street, Haifa 31048, Israel. E-mail: joyfeld{at}gmail.com ER -