TY - JOUR T1 - Renal Infarction Due to Spontaneous Renal Artery Dissection in Ehlers-Danlos Syndrome Type IV JF - The Journal of Rheumatology JO - J Rheumatol SP - 199 LP - 200 DO - 10.3899/jrheum.111034 VL - 39 IS - 1 AU - RICHARD CONWAY AU - DIANE BERGIN AU - ROBERT J. COUGHLAN AU - JOHN J. CAREY Y1 - 2012/01/01 UR - http://www.jrheum.org/content/39/1/199.abstract N2 - To the Editor:Ehlers-Danlos syndrome (EDS) type IV is an autosomal dominant disorder caused by mutations in the gene for type III procollagen (COL3A1). The phenotype is characterized by thin translucent skin with visible veins, spontaneous rupture of arteries, uterus or intestines, characteristic facial features, and easy bruising1. Median survival is 48 years, with spontaneous arterial rupture the commonest cause of death2. We describe a case of renal infarction due to spontaneous renal artery dissection in EDS, highlighting the clinical presentation and management difficulties.A 25-year-old man presented to an outlying facility in our hospital network with a 6-h history of acute severe right flank pain associated with 2 episodes of vomiting. Medical history was notable for a diagnosis of EDS type IV, diagnosed by dermal fibroblast culture at the age of 20 years. He dislocated his left shoulder at the age of 21 years and had … Address correspondence to Dr. R. Conway, Department of Rheumatology, Galway University Hospitals, Merlin Park, Galway, Ireland. E-mail: drrichardconway{at}gmail.com ER -