RT Journal Article
SR Electronic
T1 Thrombovascular Events Affect Quality of Life in Patients with Systemic Lupus Erythematosus
JF The Journal of Rheumatology
JO J Rheumatol
FD The Journal of Rheumatology
SP 1017
OP 1019
DO 10.3899/jrheum.101054
VO 38
IS 6
A1 AMARIS K. BALITSKY
A1 VALENTINA PEEVA
A1 JIANDONG SU
A1 ELAHEH AGHDASSI
A1 ERIC YEO
A1 DAFNA D. GLADMAN
A1 MURRAY B. UROWITZ
A1 PAUL R. FORTIN
YR 2011
UL http://www.jrheum.org/content/38/6/1017.abstract
AB Objective. To compare health-related quality of life (HRQOL) of patients with antiphospholipid syndrome (APS) and systemic lupus erythematosus (SLE) with and without previous thrombovascular events (TE). Methods. The Medical Outcomes Study Short-Form 36 (SF-36) was used to assess HRQOL in 5 patient groups: (1) primary APS (PAPS; n = 35); (2) APS associated to SLE (SAPS; n = 37); (3) SLE+TE without persistent positive antiphospholipid antibody (SLE+TE–aPL; n = 75); (4) SLE–TE+aPL (n = 71); and (5) SLE–TE–aPL (n = 608). Results. The data on both mental component summary and physical component summary (PCS) scores showed an impaired quality of life in all patient groups. Patients in the SLE+TE–aPL group had a lower PCS score compared to patients in the SLE–TE+aPL group. Conclusion. The combination of SLE and TE has a more negative influence on reported HRQOL, compared to having SLE or APS alone.