RT Journal Article
SR Electronic
T1 Comparison of Patients with Juvenile Psoriatic Arthritis and Nonpsoriatic Juvenile Idiopathic Arthritis: How Different Are They?
JF The Journal of Rheumatology
JO J Rheumatol
FD The Journal of Rheumatology
SP 2033
OP 2041
DO 10.3899/jrheum.080674
VO 36
IS 9
A1 YONATAN AVIEL BUTBUL
A1 PASCAL N. TYRRELL
A1 RAYFEL SCHNEIDER
A1 SANDEEP DHILLON
A1 BRIAN M. FELDMAN
A1 RONALD M. LAXER
A1 ROTRAUD K. SAURENMANN
A1 LYNN SPIEGEL
A1 BONNIE CAMERON
A1 SHIRLEY M. TSE
A1 EARL D. SILVERMAN
YR 2009
UL http://www.jrheum.org/content/36/9/2033.abstract
AB Objective. To compare the clinical features and outcome between patients with juvenile psoriatic arthritis (JPsA) and non-JPsA juvenile idiopathic arthritis (JIA). Methods. Fifty-three children with JPsA, 32 with < 5 joints in the first 6 months of disease (oligo–JPsA) and 21 (≥ 5 joints) polyarticular-onset (poly-JPsA) were compared to 53 patients with JIA who were matched by sex, age, date of diagnosis, and articular onset pattern. Results. There was no difference in the percentage of patients between the oligoarticular groups who developed extended oligoarthritis or in the percentage of patients who were positive for antinuclear antibodies. The only differences were that 25% of patients with oligo-JPsA had dactylitis compared to 0% of patients with oligo-JIA (p < 0.01) and 50% had nail pitting as compared to 18.7% (p < 0.05). In polyarticular patients the percentages with dactylitis were similar (19% vs 38%; p = 0.25). The frequency of uveitis was identical in the oligoarticular patients but a higher rate was seen in poly-JPsA compared to poly-JIA (23.8% vs 0%; p = 0.02), while contractures were more frequent in poly-JIA compared to poly-JPsA during the course of the illness (47.6% vs 14.3%; p = 0.03) but not at last followup (14.3% vs 4.7%; p = 0.6). At last followup the mean Childhood Health Assessment Questionnaire scores were similar in both the polyarticular and oligoarticular groups. Conclusion. There were only a few differences between patients with JPsA and JIA regarding disease onset, disease course, and outcome. We suggest that large, longterm prospective studies are required to accurately determine whether subdividing JIA according to psoriasis is worthwhile.