PT  - JOURNAL ARTICLE
AU  - FESER, MARIE
AU  - DERBER, LEZLIE A.
AU  - DEANE, KEVIN D.
AU  - LEZOTTE, DENNIS C.
AU  - WEISMAN, MICHAEL H.
AU  - BUCKNER, JANE H.
AU  - MIKULS, TED
AU  - O’DELL, JAMES
AU  - GREGERSEN, PETER K.
AU  - HOLERS, V. MICHAEL
AU  - NORRIS, JILL M.
TI  - Plasma 25,OH Vitamin D Concentrations Are Not Associated with Rheumatoid Arthritis (RA)-related Autoantibodies in Individuals at Elevated Risk for RA
AID  - 10.3899/jrheum.080764
DP  - 2009 May 01
TA  - The Journal of Rheumatology
PG  - 943--946
VI  - 36
IP  - 5
4099  - http://www.jrheum.org/content/36/5/943.short
4100  - http://www.jrheum.org/content/36/5/943.full
SO  - J Rheumatol2009 May 01; 36
AB  - Objective. To evaluate the association between rheumatoid arthritis (RA)-related autoantibodies and plasma 25,OH vitamin D in subjects at risk for RA. Methods. In 1210 subjects without RA, 76 were positive for anti-cyclic citrullinated peptide antibodies or for at least 2 rheumatoid factors (RF; by nephelometry: RF-IgM, RF-IgG, RF-IgA). 25,OH vitamin D was measured in these cases and 154 autoantibody-negative controls from this cohort. Results. 25,OH vitamin D levels did not differ between cases and controls (adjusted OR 1.23, 95% CI 0.93–1.63). Conclusion. Vitamin D concentrations are not associated with RA-related autoimmunity in unaffected subjects at increased risk for RA.