RT Journal Article
SR Electronic
T1 Pattern of Disease Onset, Diagnostic Delay, and Clinical Features in Juvenile Onset and Adult Onset Ankylosing Spondylitis
JF The Journal of Rheumatology
JO J Rheumatol
FD The Journal of Rheumatology
SP 2830
OP 2833
DO 10.3899/jrheum.090435
VO 36
IS 12
A1 OZGOCMEN, SALIH
A1 ARDICOGLU, OZGE
A1 KAMANLI, AYHAN
A1 KAYA, ARZU
A1 DURMUS, BEKIR
A1 YILDIRIM, KADIR
A1 BAYSAL, OZLEM
A1 GUR, ALI
A1 KARATAY, SALIHA
A1 ALTAY, ZUHAL
A1 CEVIK, REMZI
A1 ERDAL, AKIN
A1 ERSOY, YUKSEL
A1 SARAC, AYSEGUL J.
A1 TEKEOGLU, IBRAHIM
A1 UGUR, MAHIR
A1 NAS, KEMAL
A1 SENEL, KAZIM
A1 ULUSOY, HASAN
YR 2009
UL http://www.jrheum.org/content/36/12/2830.abstract
AB Objective. To assess the frequency of juvenile onset ankylosing spondylitis (JOAS) in Turkish patients with AS and to compare with adult onset AS (AOAS) in a cross-sectional study design.Methods. A total of 322 patients were recruited from the joint database of 5 university hospitals in eastern Turkey.Results. Patients with JOAS (n = 43, 13.4%) had significantly longer diagnostic delay (9.21 vs 5.08 yrs), less severe axial involvement and more prevalent uveitis (OR 2.92, 95% CI 1.25–6.79), and peripheral involvement at onset (OR 3.25, 95% CI 1.51–6.98, adjusted for current age; and OR 2.26, 95% CI 1.07–4.76, adjusted for disease duration). Patients with AOAS had higher radiographic scores and more restricted clinimetrics but similar functional limitations and quality of life.Conclusion. JOAS and AOAS had distinctive courses and Turkish patients with AS had similar features compared to other Caucasian patient populations.