RT Journal Article SR Electronic T1 IL-23R Polymorphisms in Patients with Ankylosing Spondylitis in Korea JF The Journal of Rheumatology JO J Rheumatol FD The Journal of Rheumatology SP 1003 OP 1005 DO 10.3899/jrheum.081121 VO 36 IS 5 A1 IL-HOON SUNG A1 TAE-HWAN KIM A1 SO-YOUNG BANG A1 TAE-JONG KIM A1 BITNARA LEE A1 LYNETTE PEDDLE A1 PROTON RAHMAN A1 CELIA M.T. GREENWOOD A1 PINGZHAO HU A1 ROBERT D. INMAN YR 2009 UL http://www.jrheum.org/content/36/5/1003.abstract AB Objective. IL23R polymorphisms have been shown to have a significant association with ankylosing spondylitis (AS). To date, these studies have been restricted to Caucasian patients with AS. Our study addresses this relationship in Korean patients with AS. Methods. A total of 451 patients with AS and 392 ethnically matched healthy controls were enrolled. All patients were native Koreans with AS satisfying the modified New York criteria. In total, 10 single nucleotide polymorphisms (SNP) within the IL-23R gene cluster were genotyped. Results. No IL-23R SNP were found to be associated with AS in Koreans. Conclusion. The association of IL23R and AS that is seen in Caucasian patients with AS is not present in Korean patients with AS.