RT Journal Article
SR Electronic
T1 Biological Biomarkers in Psoriatic Disease. A Review
JF The Journal of Rheumatology
JO J Rheumatol
FD The Journal of Rheumatology
SP 1443
OP 1448
VO 35
IS 7
A1 KURT de VLAM
A1 ALICE B. GOTTLIEB
A1 OLIVER FITZGERALD
YR 2008
UL http://www.jrheum.org/content/35/7/1443.abstract
AB Biomarkers are important in clinical practice because they allow quantitative assessment of diagnosis, disease processes, and treatment response. However, because development of biomarkers lags significantly behind that of drug development, absence of new and appropriate markers may slow the development of patient-tailored targeted therapies. At the 2007 Annual Meeting of the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA), members of the biomarker committee discussed the possible use of biomarkers in psoriasis and psoriatic arthritis and reviewed the results of several studies of biomarkers in the pathogenesis, diagnosis, and treatment of both the inflammatory and dermatologic aspects of psoriatic disease. We review those discussions.