TY - JOUR T1 - Making Tumor Necrosis Factor Blockers Safer: A Prescriber’s Consumptive Challenge JF - The Journal of Rheumatology JO - J Rheumatol SP - 1238 LP - 1239 VL - 35 IS - 7 AU - JOSEPH KEANE AU - CLIONA NÍ CHEALLAIGH Y1 - 2008/07/01 UR - http://www.jrheum.org/content/35/7/1238.abstract N2 - Latent tuberculosis (TB) infection is firmly on the prescriber’s agenda Until recently the diagnosis and treatment of latent TB infection (LTBI) has been the preserve of countries with a low prevalence of TB (under 10 patients per 100,000 population per year). These countries were seeking to eliminate the epidemic and sought to target treatment of the asymptomatic infection in high-risk individuals. The notion was to nearly eliminate the 5%–10% chance of TB reactivation in the person with LTBI, and thus prevent TB in that person, as well as preventing about 12 new infections that would be the consequence of… ER -