RT Journal Article
SR Electronic
T1 Evaluation of the presentation of systemic onset juvenile rheumatoid arthritis: data from the Pennsylvania Systemic Onset Juvenile Arthritis Registry (PASOJAR).
JF The Journal of Rheumatology
JO J Rheumatol
FD The Journal of Rheumatology
SP 343
OP 348
VO 35
IS 2
A1 Edward M Behrens
A1 Timothy Beukelman
A1 Lisa Gallo
A1 Julie Spangler
A1 Margalit Rosenkranz
A1 Thaschawee Arkachaisri
A1 Rosanne Ayala
A1 Brandt Groh
A1 Terri H Finkel
A1 Randy Q Cron
YR 2008
UL http://www.jrheum.org/content/35/2/343.abstract
AB OBJECTIVE: To characterize the initial clinical and laboratory features of patients with systemic onset juvenile rheumatoid arthritis (soJRA) through a Web-based registry. METHODS: Patients diagnosed with soJRA in the last 15 years at 3 medical centers in Pennsylvania were identified. Data were collected retrospectively using a Web-based interface in compliance with patient privacy standards. Inferential statistics were used to compare features of patients with and without macrophage activation syndrome. RESULTS: We identified 136 patients; 88% of patients presented with arthritis (8% mono-, 45% oligo-, 47% polyarticular). The most common joints involved were the knee (68% of patients with arthritis), wrist (68%), and ankle (57%). The International League of Associations for Rheumatology criteria for systemic juvenile idiopathic arthritis (SJIA) identified only 30% of patients at presentation. CONCLUSION: We successfully characterized the presenting features of a relatively rare disease, soJRA, through the use of a Web-based registry. Current classification criteria for SJIA may not be particularly sensitive for diagnosis at presentation.