RT Journal Article SR Electronic T1 Ischemic scleroderma wounds successfully treated with hyperbaric oxygen therapy. JF The Journal of Rheumatology JO J Rheumatol FD The Journal of Rheumatology SP 1694 OP 1696 VO 33 IS 8 A1 Y Michael Markus A1 Mary J Bell A1 A Wayne Evans YR 2006 UL http://www.jrheum.org/content/33/8/1694.abstract AB Hyperbaric oxygen therapy (HBOT) has been used to treat refractory wounds for the last several decades, with the majority of research focusing on wounds secondary to arterial insufficiency. We describe 2 patients with scleroderma with intractable bilateral extremity ulcers. Local ischemia was identified using transcutaneous oximetry. Each patient then underwent 30 treatments of HBOT at a relative depth of 2.4 ATA with resulting wound healing. This is the first reported successful use of HBOT to treat scleroderma ulcers, and may represent an unrecognized treatment option for these notoriously difficult chronic wounds.