PT - JOURNAL ARTICLE AU - Y Michael Markus AU - Mary J Bell AU - A Wayne Evans TI - Ischemic scleroderma wounds successfully treated with hyperbaric oxygen therapy. DP - 2006 Aug 01 TA - The Journal of Rheumatology PG - 1694--1696 VI - 33 IP - 8 4099 - http://www.jrheum.org/content/33/8/1694.short 4100 - http://www.jrheum.org/content/33/8/1694.full SO - J Rheumatol2006 Aug 01; 33 AB - Hyperbaric oxygen therapy (HBOT) has been used to treat refractory wounds for the last several decades, with the majority of research focusing on wounds secondary to arterial insufficiency. We describe 2 patients with scleroderma with intractable bilateral extremity ulcers. Local ischemia was identified using transcutaneous oximetry. Each patient then underwent 30 treatments of HBOT at a relative depth of 2.4 ATA with resulting wound healing. This is the first reported successful use of HBOT to treat scleroderma ulcers, and may represent an unrecognized treatment option for these notoriously difficult chronic wounds.