RT Journal Article
SR Electronic
T1 Minimal clinically important improvement and patient acceptable symptom state for subjective outcome measures in rheumatic disorders.
JF The Journal of Rheumatology
JO J Rheumatol
FD The Journal of Rheumatology
SP 1188
OP 1193
VO 34
IS 5
A1 Tubach, Florence
A1 Ravaud, Philippe
A1 Beaton, Dorcas
A1 Boers, Maarten
A1 Bombardier, Claire
A1 Felson, David T
A1 van der Heijde, Desireé
A1 Wells, George
A1 Dougados, Maxime
YR 2007
UL http://www.jrheum.org/content/34/5/1188.abstract
AB The concepts of minimal clinically important improvement (MCII) and patient acceptable symptomatic state (PASS) could help in interpreting results of trials involving patient-reported outcomes by translating the response at the group level (change in mean scores) into more clinically meaningful information by addressing the patient level as "therapeutic success (yes/no)." The aims of the special interest group (SIG) at OMERACT 8 were to discuss specific issues concerning the MCII and PASS concepts, especially the wording of the external anchor questions used to determine the MCII and PASS estimates, and to move toward a consensus for the cutoff values to use as the MCII and PASS in the different outcome criteria. The purpose of this SIG at OMERACT 8 was to inform participants of the MCII and PASS concepts and to agree on MCII and PASS values for pain, patient global assessment, and functional impairment.