RT Journal Article
SR Electronic
T1 Male osteoporosis with vertebral fractures? Look for ankylosing spondylitis! A report of 10 cases.
JF The Journal of Rheumatology
JO J Rheumatol
FD The Journal of Rheumatology
SP 2271
OP 2272
VO 34
IS 11
A1 Michel Laroche
A1 Slim Lassoued
A1 Thierry Billey
A1 Jacques Bernard
A1 Bernard Mazi
YR 2007
UL http://www.jrheum.org/content/34/11/2271.abstract
AB OBJECTIVE: Several authors have described the association of ankylosing spondylitis (AS) and osteoporosis. Usually vertebral fractures complicate severe AS. METHODS: We report a series of 10 men in whom benign spondyloarthropathy was discovered during etiological investigation for osteoporosis. Eight patients had B27+ AS and 2 had psoriatic arthritis with axial involvement. The mean number of vertebral fractures was 1.5. No patient had an appendicular fracture. RESULTS: Phosphorus and calcium levels and measurements of 25OHD3, parathyroid hormone, osteocalcin, and serum CTX were in the normal range. The decrease in bone mineral density was greater in the spine (mean T-score at L2-L4 -2.95, mean total hip T-score -1.67). CONCLUSION: Osteoporosis with fractures may reveal benign spondyloarthropathy whose clinical expression is sometimes incomplete. Our findings demonstrate that osteoporosis is not always correlated with the severity of AS.