RT Journal Article
SR Electronic
T1 Pulmonary complications of infliximab therapy in patients with rheumatoid arthritis.
JF The Journal of Rheumatology
JO J Rheumatol
FD The Journal of Rheumatology
SP 622
OP 628
VO 33
IS 3
A1 Andrew J K Ostör
A1 Edwin R Chilvers
A1 Margaret F Somerville
A1 Anita Y N Lim
A1 Suzanne E Lane
A1 Adrian J Crisp
A1 David G I Scott
YR 2006
UL http://www.jrheum.org/content/33/3/622.abstract
AB We describe 5 patients with rheumatoid arthritis (RA) who developed pulmonary complications following infliximab therapy; 4 patients had preexisting usual interstitial pneumonia. As the pathophysiology of the pulmonary insult is unknown, we advise caution in the use of anti-tumor necrosis factor-alpha therapy in patients with RA with underlying lung disease of sufficient severity to withhold methotrexate treatment.