Smoking Cessation and Gout Risk in Indigenous Populations: A Call for Causal Inference and Multiethnic Mendelian Randomization

Abstract

Fanning et al¹ provide critical insights into the association between smoking history and gout prevalence in the Māori population of Aotearoa New Zealand. The strengths of the study are its robust adjustment for confounders like BMI, kidney function, and socioeconomic factors, and its focus on Indigenous health disparities, a perspective often ignored in gout research.