Research ArticleArticle
Open Access
Impact of Physician-Defined Flares on Quality of Life and Work Impairment: An International Survey of 2238 Patients With Psoriatic Arthritis
Ana-Maria Orbai, William Tillett, Suzanne Grieb, Steve Peterson, Elizabeth Holdsworth, Nicola Booth, Soumya D. Chakravarty and Laure Gossec
The Journal of Rheumatology August 2022, jrheum.211302; DOI: https://doi.org/10.3899/jrheum.211302
Ana-Maria Orbai
The analysis described here using data from the Adelphi PsA IV Disease Specific Programme was funded by Janssen. A.M. Orbai, MD, MHS, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; W. Tillett, PhD, Royal National Hospital for Rheumatic Disease, and University of Bath, Pharmacy and Pharmacology and Centre for Therapeutic Innovation, Bath, UK; S. Grieb, PhD, Patient Research Partner, Baltimore, Maryland, USA; S. Peterson, MSc, Janssen Global Services, Horsham, Pennsylvania, USA; E.A. Holdsworth, MSc, N. Booth, MSc, Adelphi Real World, Bollington, UK; S.D. Chakravarty, MD, Janssen Scientific Affairs, Horsham, and Drexel University College of Medicine, Philadelphia, Pennsylvania, USA; L. Gossec, MD, PhD, Sorbonne Université, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique, and Pitié-Salpêtrière Hospital, AP-HP, Sorbonne Université, Rheumatology Department, Paris, France. AMO has received research grants to Johns Hopkins University from AbbVie, Amgen, Celgene, Horizon, Janssen, Eli Lilly, Novartis, and Pfizer; and consulting fees from BMS, Janssen, Eli Lilly, Novartis, Pfizer, and UCB. WT has received research grants from AbbVie, Celgene, Janssen, GSK, and Eli Lilly; and consulting fees from AbbVie, Amgen, Celgene, Janssen, Eli Lilly, MSD, Novartis, Pfizer, GSK, and UCB. SG is engaged in the research or services as a private consultant and not in their capacity as a Johns Hopkins faculty member. NB and EAH are employees of Adelphi Real World. SP and SDC are employees of Janssen. LG has received research grants from Amgen, Galapagos, Janssen, Eli Lilly, Pfizer, Sandoz, and Sanofi; and consulting fees from AbbVie, Amgen, BMS, Biogen, Celgene, Gilead, Janssen, Eli Lilly, Novartis, Pfizer, Samsung Bioepis, Sanofi-Aventis, and UCB. Address correspondence to Dr. A.M. Orbai, Johns Hopkins University School of Medicine, Division of Rheumatology, 5200 Eastern Avenue, Baltimore, MD 21224, USA. Email: aorbai1@jhmi.edu. Accepted for publication July 26, 2022.
William Tillett
The analysis described here using data from the Adelphi PsA IV Disease Specific Programme was funded by Janssen. A.M. Orbai, MD, MHS, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; W. Tillett, PhD, Royal National Hospital for Rheumatic Disease, and University of Bath, Pharmacy and Pharmacology and Centre for Therapeutic Innovation, Bath, UK; S. Grieb, PhD, Patient Research Partner, Baltimore, Maryland, USA; S. Peterson, MSc, Janssen Global Services, Horsham, Pennsylvania, USA; E.A. Holdsworth, MSc, N. Booth, MSc, Adelphi Real World, Bollington, UK; S.D. Chakravarty, MD, Janssen Scientific Affairs, Horsham, and Drexel University College of Medicine, Philadelphia, Pennsylvania, USA; L. Gossec, MD, PhD, Sorbonne Université, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique, and Pitié-Salpêtrière Hospital, AP-HP, Sorbonne Université, Rheumatology Department, Paris, France. AMO has received research grants to Johns Hopkins University from AbbVie, Amgen, Celgene, Horizon, Janssen, Eli Lilly, Novartis, and Pfizer; and consulting fees from BMS, Janssen, Eli Lilly, Novartis, Pfizer, and UCB. WT has received research grants from AbbVie, Celgene, Janssen, GSK, and Eli Lilly; and consulting fees from AbbVie, Amgen, Celgene, Janssen, Eli Lilly, MSD, Novartis, Pfizer, GSK, and UCB. SG is engaged in the research or services as a private consultant and not in their capacity as a Johns Hopkins faculty member. NB and EAH are employees of Adelphi Real World. SP and SDC are employees of Janssen. LG has received research grants from Amgen, Galapagos, Janssen, Eli Lilly, Pfizer, Sandoz, and Sanofi; and consulting fees from AbbVie, Amgen, BMS, Biogen, Celgene, Gilead, Janssen, Eli Lilly, Novartis, Pfizer, Samsung Bioepis, Sanofi-Aventis, and UCB. Address correspondence to Dr. A.M. Orbai, Johns Hopkins University School of Medicine, Division of Rheumatology, 5200 Eastern Avenue, Baltimore, MD 21224, USA. Email: aorbai1@jhmi.edu. Accepted for publication July 26, 2022.
Suzanne Grieb
The analysis described here using data from the Adelphi PsA IV Disease Specific Programme was funded by Janssen. A.M. Orbai, MD, MHS, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; W. Tillett, PhD, Royal National Hospital for Rheumatic Disease, and University of Bath, Pharmacy and Pharmacology and Centre for Therapeutic Innovation, Bath, UK; S. Grieb, PhD, Patient Research Partner, Baltimore, Maryland, USA; S. Peterson, MSc, Janssen Global Services, Horsham, Pennsylvania, USA; E.A. Holdsworth, MSc, N. Booth, MSc, Adelphi Real World, Bollington, UK; S.D. Chakravarty, MD, Janssen Scientific Affairs, Horsham, and Drexel University College of Medicine, Philadelphia, Pennsylvania, USA; L. Gossec, MD, PhD, Sorbonne Université, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique, and Pitié-Salpêtrière Hospital, AP-HP, Sorbonne Université, Rheumatology Department, Paris, France. AMO has received research grants to Johns Hopkins University from AbbVie, Amgen, Celgene, Horizon, Janssen, Eli Lilly, Novartis, and Pfizer; and consulting fees from BMS, Janssen, Eli Lilly, Novartis, Pfizer, and UCB. WT has received research grants from AbbVie, Celgene, Janssen, GSK, and Eli Lilly; and consulting fees from AbbVie, Amgen, Celgene, Janssen, Eli Lilly, MSD, Novartis, Pfizer, GSK, and UCB. SG is engaged in the research or services as a private consultant and not in their capacity as a Johns Hopkins faculty member. NB and EAH are employees of Adelphi Real World. SP and SDC are employees of Janssen. LG has received research grants from Amgen, Galapagos, Janssen, Eli Lilly, Pfizer, Sandoz, and Sanofi; and consulting fees from AbbVie, Amgen, BMS, Biogen, Celgene, Gilead, Janssen, Eli Lilly, Novartis, Pfizer, Samsung Bioepis, Sanofi-Aventis, and UCB. Address correspondence to Dr. A.M. Orbai, Johns Hopkins University School of Medicine, Division of Rheumatology, 5200 Eastern Avenue, Baltimore, MD 21224, USA. Email: aorbai1@jhmi.edu. Accepted for publication July 26, 2022.
Steve Peterson
The analysis described here using data from the Adelphi PsA IV Disease Specific Programme was funded by Janssen. A.M. Orbai, MD, MHS, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; W. Tillett, PhD, Royal National Hospital for Rheumatic Disease, and University of Bath, Pharmacy and Pharmacology and Centre for Therapeutic Innovation, Bath, UK; S. Grieb, PhD, Patient Research Partner, Baltimore, Maryland, USA; S. Peterson, MSc, Janssen Global Services, Horsham, Pennsylvania, USA; E.A. Holdsworth, MSc, N. Booth, MSc, Adelphi Real World, Bollington, UK; S.D. Chakravarty, MD, Janssen Scientific Affairs, Horsham, and Drexel University College of Medicine, Philadelphia, Pennsylvania, USA; L. Gossec, MD, PhD, Sorbonne Université, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique, and Pitié-Salpêtrière Hospital, AP-HP, Sorbonne Université, Rheumatology Department, Paris, France. AMO has received research grants to Johns Hopkins University from AbbVie, Amgen, Celgene, Horizon, Janssen, Eli Lilly, Novartis, and Pfizer; and consulting fees from BMS, Janssen, Eli Lilly, Novartis, Pfizer, and UCB. WT has received research grants from AbbVie, Celgene, Janssen, GSK, and Eli Lilly; and consulting fees from AbbVie, Amgen, Celgene, Janssen, Eli Lilly, MSD, Novartis, Pfizer, GSK, and UCB. SG is engaged in the research or services as a private consultant and not in their capacity as a Johns Hopkins faculty member. NB and EAH are employees of Adelphi Real World. SP and SDC are employees of Janssen. LG has received research grants from Amgen, Galapagos, Janssen, Eli Lilly, Pfizer, Sandoz, and Sanofi; and consulting fees from AbbVie, Amgen, BMS, Biogen, Celgene, Gilead, Janssen, Eli Lilly, Novartis, Pfizer, Samsung Bioepis, Sanofi-Aventis, and UCB. Address correspondence to Dr. A.M. Orbai, Johns Hopkins University School of Medicine, Division of Rheumatology, 5200 Eastern Avenue, Baltimore, MD 21224, USA. Email: aorbai1@jhmi.edu. Accepted for publication July 26, 2022.
Elizabeth Holdsworth
The analysis described here using data from the Adelphi PsA IV Disease Specific Programme was funded by Janssen. A.M. Orbai, MD, MHS, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; W. Tillett, PhD, Royal National Hospital for Rheumatic Disease, and University of Bath, Pharmacy and Pharmacology and Centre for Therapeutic Innovation, Bath, UK; S. Grieb, PhD, Patient Research Partner, Baltimore, Maryland, USA; S. Peterson, MSc, Janssen Global Services, Horsham, Pennsylvania, USA; E.A. Holdsworth, MSc, N. Booth, MSc, Adelphi Real World, Bollington, UK; S.D. Chakravarty, MD, Janssen Scientific Affairs, Horsham, and Drexel University College of Medicine, Philadelphia, Pennsylvania, USA; L. Gossec, MD, PhD, Sorbonne Université, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique, and Pitié-Salpêtrière Hospital, AP-HP, Sorbonne Université, Rheumatology Department, Paris, France. AMO has received research grants to Johns Hopkins University from AbbVie, Amgen, Celgene, Horizon, Janssen, Eli Lilly, Novartis, and Pfizer; and consulting fees from BMS, Janssen, Eli Lilly, Novartis, Pfizer, and UCB. WT has received research grants from AbbVie, Celgene, Janssen, GSK, and Eli Lilly; and consulting fees from AbbVie, Amgen, Celgene, Janssen, Eli Lilly, MSD, Novartis, Pfizer, GSK, and UCB. SG is engaged in the research or services as a private consultant and not in their capacity as a Johns Hopkins faculty member. NB and EAH are employees of Adelphi Real World. SP and SDC are employees of Janssen. LG has received research grants from Amgen, Galapagos, Janssen, Eli Lilly, Pfizer, Sandoz, and Sanofi; and consulting fees from AbbVie, Amgen, BMS, Biogen, Celgene, Gilead, Janssen, Eli Lilly, Novartis, Pfizer, Samsung Bioepis, Sanofi-Aventis, and UCB. Address correspondence to Dr. A.M. Orbai, Johns Hopkins University School of Medicine, Division of Rheumatology, 5200 Eastern Avenue, Baltimore, MD 21224, USA. Email: aorbai1@jhmi.edu. Accepted for publication July 26, 2022.
Nicola Booth
The analysis described here using data from the Adelphi PsA IV Disease Specific Programme was funded by Janssen. A.M. Orbai, MD, MHS, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; W. Tillett, PhD, Royal National Hospital for Rheumatic Disease, and University of Bath, Pharmacy and Pharmacology and Centre for Therapeutic Innovation, Bath, UK; S. Grieb, PhD, Patient Research Partner, Baltimore, Maryland, USA; S. Peterson, MSc, Janssen Global Services, Horsham, Pennsylvania, USA; E.A. Holdsworth, MSc, N. Booth, MSc, Adelphi Real World, Bollington, UK; S.D. Chakravarty, MD, Janssen Scientific Affairs, Horsham, and Drexel University College of Medicine, Philadelphia, Pennsylvania, USA; L. Gossec, MD, PhD, Sorbonne Université, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique, and Pitié-Salpêtrière Hospital, AP-HP, Sorbonne Université, Rheumatology Department, Paris, France. AMO has received research grants to Johns Hopkins University from AbbVie, Amgen, Celgene, Horizon, Janssen, Eli Lilly, Novartis, and Pfizer; and consulting fees from BMS, Janssen, Eli Lilly, Novartis, Pfizer, and UCB. WT has received research grants from AbbVie, Celgene, Janssen, GSK, and Eli Lilly; and consulting fees from AbbVie, Amgen, Celgene, Janssen, Eli Lilly, MSD, Novartis, Pfizer, GSK, and UCB. SG is engaged in the research or services as a private consultant and not in their capacity as a Johns Hopkins faculty member. NB and EAH are employees of Adelphi Real World. SP and SDC are employees of Janssen. LG has received research grants from Amgen, Galapagos, Janssen, Eli Lilly, Pfizer, Sandoz, and Sanofi; and consulting fees from AbbVie, Amgen, BMS, Biogen, Celgene, Gilead, Janssen, Eli Lilly, Novartis, Pfizer, Samsung Bioepis, Sanofi-Aventis, and UCB. Address correspondence to Dr. A.M. Orbai, Johns Hopkins University School of Medicine, Division of Rheumatology, 5200 Eastern Avenue, Baltimore, MD 21224, USA. Email: aorbai1@jhmi.edu. Accepted for publication July 26, 2022.
Soumya D. Chakravarty
The analysis described here using data from the Adelphi PsA IV Disease Specific Programme was funded by Janssen. A.M. Orbai, MD, MHS, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; W. Tillett, PhD, Royal National Hospital for Rheumatic Disease, and University of Bath, Pharmacy and Pharmacology and Centre for Therapeutic Innovation, Bath, UK; S. Grieb, PhD, Patient Research Partner, Baltimore, Maryland, USA; S. Peterson, MSc, Janssen Global Services, Horsham, Pennsylvania, USA; E.A. Holdsworth, MSc, N. Booth, MSc, Adelphi Real World, Bollington, UK; S.D. Chakravarty, MD, Janssen Scientific Affairs, Horsham, and Drexel University College of Medicine, Philadelphia, Pennsylvania, USA; L. Gossec, MD, PhD, Sorbonne Université, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique, and Pitié-Salpêtrière Hospital, AP-HP, Sorbonne Université, Rheumatology Department, Paris, France. AMO has received research grants to Johns Hopkins University from AbbVie, Amgen, Celgene, Horizon, Janssen, Eli Lilly, Novartis, and Pfizer; and consulting fees from BMS, Janssen, Eli Lilly, Novartis, Pfizer, and UCB. WT has received research grants from AbbVie, Celgene, Janssen, GSK, and Eli Lilly; and consulting fees from AbbVie, Amgen, Celgene, Janssen, Eli Lilly, MSD, Novartis, Pfizer, GSK, and UCB. SG is engaged in the research or services as a private consultant and not in their capacity as a Johns Hopkins faculty member. NB and EAH are employees of Adelphi Real World. SP and SDC are employees of Janssen. LG has received research grants from Amgen, Galapagos, Janssen, Eli Lilly, Pfizer, Sandoz, and Sanofi; and consulting fees from AbbVie, Amgen, BMS, Biogen, Celgene, Gilead, Janssen, Eli Lilly, Novartis, Pfizer, Samsung Bioepis, Sanofi-Aventis, and UCB. Address correspondence to Dr. A.M. Orbai, Johns Hopkins University School of Medicine, Division of Rheumatology, 5200 Eastern Avenue, Baltimore, MD 21224, USA. Email: aorbai1@jhmi.edu. Accepted for publication July 26, 2022.
Laure Gossec
The analysis described here using data from the Adelphi PsA IV Disease Specific Programme was funded by Janssen. A.M. Orbai, MD, MHS, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; W. Tillett, PhD, Royal National Hospital for Rheumatic Disease, and University of Bath, Pharmacy and Pharmacology and Centre for Therapeutic Innovation, Bath, UK; S. Grieb, PhD, Patient Research Partner, Baltimore, Maryland, USA; S. Peterson, MSc, Janssen Global Services, Horsham, Pennsylvania, USA; E.A. Holdsworth, MSc, N. Booth, MSc, Adelphi Real World, Bollington, UK; S.D. Chakravarty, MD, Janssen Scientific Affairs, Horsham, and Drexel University College of Medicine, Philadelphia, Pennsylvania, USA; L. Gossec, MD, PhD, Sorbonne Université, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique, and Pitié-Salpêtrière Hospital, AP-HP, Sorbonne Université, Rheumatology Department, Paris, France. AMO has received research grants to Johns Hopkins University from AbbVie, Amgen, Celgene, Horizon, Janssen, Eli Lilly, Novartis, and Pfizer; and consulting fees from BMS, Janssen, Eli Lilly, Novartis, Pfizer, and UCB. WT has received research grants from AbbVie, Celgene, Janssen, GSK, and Eli Lilly; and consulting fees from AbbVie, Amgen, Celgene, Janssen, Eli Lilly, MSD, Novartis, Pfizer, GSK, and UCB. SG is engaged in the research or services as a private consultant and not in their capacity as a Johns Hopkins faculty member. NB and EAH are employees of Adelphi Real World. SP and SDC are employees of Janssen. LG has received research grants from Amgen, Galapagos, Janssen, Eli Lilly, Pfizer, Sandoz, and Sanofi; and consulting fees from AbbVie, Amgen, BMS, Biogen, Celgene, Gilead, Janssen, Eli Lilly, Novartis, Pfizer, Samsung Bioepis, Sanofi-Aventis, and UCB. Address correspondence to Dr. A.M. Orbai, Johns Hopkins University School of Medicine, Division of Rheumatology, 5200 Eastern Avenue, Baltimore, MD 21224, USA. Email: aorbai1@jhmi.edu. Accepted for publication July 26, 2022.
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In this issue
The Journal of Rheumatology
Vol. 51, Issue 4
1 Apr 2024
Impact of Physician-Defined Flares on Quality of Life and Work Impairment: An International Survey of 2238 Patients With Psoriatic Arthritis
Ana-Maria Orbai, William Tillett, Suzanne Grieb, Steve Peterson, Elizabeth Holdsworth, Nicola Booth, Soumya D. Chakravarty, Laure Gossec
The Journal of Rheumatology Aug 2022, jrheum.211302; DOI: 10.3899/jrheum.211302
Impact of Physician-Defined Flares on Quality of Life and Work Impairment: An International Survey of 2238 Patients With Psoriatic Arthritis
Ana-Maria Orbai, William Tillett, Suzanne Grieb, Steve Peterson, Elizabeth Holdsworth, Nicola Booth, Soumya D. Chakravarty, Laure Gossec
The Journal of Rheumatology Aug 2022, jrheum.211302; DOI: 10.3899/jrheum.211302