Research ArticleArticle
Coexistence of Anti-Ro52 Antibodies in Anti-MDA5 Antibody–Positive Dermatomyositis Is Highly Associated With Rapidly Progressive Interstitial Lung Disease and Mortality Risk
Chengyin Lv, Hanxiao You, Lingxiao Xu, Lei Wang, Fenghong Yuan, Ju Li, Min Wu, Shiliang Zhou, Zhanyun Da, Jie Qian, Hua Wei, Wei Yan, Lei Zhou, Yan Wang, Songlou Yin, Dongmei Zhou, Jian Wu, Yan Lu, Dinglei Su, Zhichun Liu, Lin Liu, Longxin Ma, Xiaoyan Xu, Yinshan Zang, Huijie Liu, Tianli Ren, Fang Wang, Miaojia Zhang and Wenfeng Tan
The Journal of Rheumatology June 2022, jrheum.220139; DOI: https://doi.org/10.3899/jrheum.220139
Chengyin Lv
This work was supported by the National Natural Science Foundation of China (grants 81971532, 81971533, and 82071827), the Special Financial Grant from the China Postdoctoral Science Foundation (grant 2021TQ0134), the Natural Science Foundation of Jiangsu Province (grant BK20210964), and the Doctoral Program of Entrepreneurship and Innovation in Jiangsu Province (grant JSSCBS20211479). The funders had no role in the study design, the data collection and analysis, the decision to publish, or the preparation of the manuscript. C. Lv, MD, H. You, MD, PhD, L. Xu, MD, PhD, L. Wang, MD, PhD, M. Zhang, MD, W. Tan, MD, PhD, Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing; F. Yuan, MD, Department of Rheumatology and Immunology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi; J. Li, MD, Department of Rheumatology, Huai'an First People's Hospital, Huai'an, Jiangsu; M. Wu, MD, S. Zhou, MD, Department of Rheumatology, The First People's Hospital of Changzhou, Changzhou; Z. Da, MD, J. Qian, MD, Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong; H. Wei, MD, W. Yan, MD, Department of Rheumatology, Northern Jiangsu People's Hospital, Yangzhou; L. Zhou, MD, Y. Wang, MD, Department of Rheumatology, Changzhou No.2 People's Hospital, Changzhou; S. Yin, MD, D. Zhou, MD, Department of Rheumatology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou; J. Wu, MD, Department of Rheumatology, The First Affiliated Hospital of Soochow University, Suzhou; Y. Lu, MD, Department of Rheumatology, Jiangsu Province Hospital of Chinese Medicine, Nanjing; D. Su, MD, Department of Rheumatology, Nanjing First Hospital, Nanjing; Z. Liu, MD, Department of Rheumatology, The Second Affiliated Hospital of Soochow University, Suzhou; L. Liu, MD, Department of Rheumatology, Xuzhou Central Hospital, Xuzhou; L. Ma, MD, Department of Rheumatology, Yancheng No.1 People's Hospital, Yancheng; X. Xu, MD, Department of Rheumatology, Zhongda Hospital Southeast University, Nanjing; Y. Zang, MD, Department of Rheumatology, The Affiliated Suqian First People's Hospital of Nanjing Medical University, Suqian; H. Liu, MD, Department of Rheumatology, The First People's Hospital of Lianyungang, Lianyungang; T. Ren, MD, Department of Rheumatology, Wuxi No.2 People's Hospital, Wuxi; F. Wang, MD, PhD, Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, China, Nanjing, Jiangsu, China. C. Lv and H. You are joint first authors and contributed equally to this manuscript. W. Tan and M. Zhang contributed equally to this manuscript. Address correspondence to Dr. W. Tan or Dr. M. Zhang, Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China. Email: tw2006@njmu.edu.cn or mjzhang@njmu.edu.cn. Accepted for publication June 2, 2022.
Hanxiao You
This work was supported by the National Natural Science Foundation of China (grants 81971532, 81971533, and 82071827), the Special Financial Grant from the China Postdoctoral Science Foundation (grant 2021TQ0134), the Natural Science Foundation of Jiangsu Province (grant BK20210964), and the Doctoral Program of Entrepreneurship and Innovation in Jiangsu Province (grant JSSCBS20211479). The funders had no role in the study design, the data collection and analysis, the decision to publish, or the preparation of the manuscript. C. Lv, MD, H. You, MD, PhD, L. Xu, MD, PhD, L. Wang, MD, PhD, M. Zhang, MD, W. Tan, MD, PhD, Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing; F. Yuan, MD, Department of Rheumatology and Immunology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi; J. Li, MD, Department of Rheumatology, Huai'an First People's Hospital, Huai'an, Jiangsu; M. Wu, MD, S. Zhou, MD, Department of Rheumatology, The First People's Hospital of Changzhou, Changzhou; Z. Da, MD, J. Qian, MD, Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong; H. Wei, MD, W. Yan, MD, Department of Rheumatology, Northern Jiangsu People's Hospital, Yangzhou; L. Zhou, MD, Y. Wang, MD, Department of Rheumatology, Changzhou No.2 People's Hospital, Changzhou; S. Yin, MD, D. Zhou, MD, Department of Rheumatology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou; J. Wu, MD, Department of Rheumatology, The First Affiliated Hospital of Soochow University, Suzhou; Y. Lu, MD, Department of Rheumatology, Jiangsu Province Hospital of Chinese Medicine, Nanjing; D. Su, MD, Department of Rheumatology, Nanjing First Hospital, Nanjing; Z. Liu, MD, Department of Rheumatology, The Second Affiliated Hospital of Soochow University, Suzhou; L. Liu, MD, Department of Rheumatology, Xuzhou Central Hospital, Xuzhou; L. Ma, MD, Department of Rheumatology, Yancheng No.1 People's Hospital, Yancheng; X. Xu, MD, Department of Rheumatology, Zhongda Hospital Southeast University, Nanjing; Y. Zang, MD, Department of Rheumatology, The Affiliated Suqian First People's Hospital of Nanjing Medical University, Suqian; H. Liu, MD, Department of Rheumatology, The First People's Hospital of Lianyungang, Lianyungang; T. Ren, MD, Department of Rheumatology, Wuxi No.2 People's Hospital, Wuxi; F. Wang, MD, PhD, Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, China, Nanjing, Jiangsu, China. C. Lv and H. You are joint first authors and contributed equally to this manuscript. W. Tan and M. Zhang contributed equally to this manuscript. Address correspondence to Dr. W. Tan or Dr. M. Zhang, Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China. Email: tw2006@njmu.edu.cn or mjzhang@njmu.edu.cn. Accepted for publication June 2, 2022.
Lingxiao Xu
This work was supported by the National Natural Science Foundation of China (grants 81971532, 81971533, and 82071827), the Special Financial Grant from the China Postdoctoral Science Foundation (grant 2021TQ0134), the Natural Science Foundation of Jiangsu Province (grant BK20210964), and the Doctoral Program of Entrepreneurship and Innovation in Jiangsu Province (grant JSSCBS20211479). The funders had no role in the study design, the data collection and analysis, the decision to publish, or the preparation of the manuscript. C. Lv, MD, H. You, MD, PhD, L. Xu, MD, PhD, L. Wang, MD, PhD, M. Zhang, MD, W. Tan, MD, PhD, Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing; F. Yuan, MD, Department of Rheumatology and Immunology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi; J. Li, MD, Department of Rheumatology, Huai'an First People's Hospital, Huai'an, Jiangsu; M. Wu, MD, S. Zhou, MD, Department of Rheumatology, The First People's Hospital of Changzhou, Changzhou; Z. Da, MD, J. Qian, MD, Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong; H. Wei, MD, W. Yan, MD, Department of Rheumatology, Northern Jiangsu People's Hospital, Yangzhou; L. Zhou, MD, Y. Wang, MD, Department of Rheumatology, Changzhou No.2 People's Hospital, Changzhou; S. Yin, MD, D. Zhou, MD, Department of Rheumatology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou; J. Wu, MD, Department of Rheumatology, The First Affiliated Hospital of Soochow University, Suzhou; Y. Lu, MD, Department of Rheumatology, Jiangsu Province Hospital of Chinese Medicine, Nanjing; D. Su, MD, Department of Rheumatology, Nanjing First Hospital, Nanjing; Z. Liu, MD, Department of Rheumatology, The Second Affiliated Hospital of Soochow University, Suzhou; L. Liu, MD, Department of Rheumatology, Xuzhou Central Hospital, Xuzhou; L. Ma, MD, Department of Rheumatology, Yancheng No.1 People's Hospital, Yancheng; X. Xu, MD, Department of Rheumatology, Zhongda Hospital Southeast University, Nanjing; Y. Zang, MD, Department of Rheumatology, The Affiliated Suqian First People's Hospital of Nanjing Medical University, Suqian; H. Liu, MD, Department of Rheumatology, The First People's Hospital of Lianyungang, Lianyungang; T. Ren, MD, Department of Rheumatology, Wuxi No.2 People's Hospital, Wuxi; F. Wang, MD, PhD, Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, China, Nanjing, Jiangsu, China. C. Lv and H. You are joint first authors and contributed equally to this manuscript. W. Tan and M. Zhang contributed equally to this manuscript. Address correspondence to Dr. W. Tan or Dr. M. Zhang, Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China. Email: tw2006@njmu.edu.cn or mjzhang@njmu.edu.cn. Accepted for publication June 2, 2022.
Lei Wang
This work was supported by the National Natural Science Foundation of China (grants 81971532, 81971533, and 82071827), the Special Financial Grant from the China Postdoctoral Science Foundation (grant 2021TQ0134), the Natural Science Foundation of Jiangsu Province (grant BK20210964), and the Doctoral Program of Entrepreneurship and Innovation in Jiangsu Province (grant JSSCBS20211479). The funders had no role in the study design, the data collection and analysis, the decision to publish, or the preparation of the manuscript. C. Lv, MD, H. You, MD, PhD, L. Xu, MD, PhD, L. Wang, MD, PhD, M. Zhang, MD, W. Tan, MD, PhD, Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing; F. Yuan, MD, Department of Rheumatology and Immunology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi; J. Li, MD, Department of Rheumatology, Huai'an First People's Hospital, Huai'an, Jiangsu; M. Wu, MD, S. Zhou, MD, Department of Rheumatology, The First People's Hospital of Changzhou, Changzhou; Z. Da, MD, J. Qian, MD, Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong; H. Wei, MD, W. Yan, MD, Department of Rheumatology, Northern Jiangsu People's Hospital, Yangzhou; L. Zhou, MD, Y. Wang, MD, Department of Rheumatology, Changzhou No.2 People's Hospital, Changzhou; S. Yin, MD, D. Zhou, MD, Department of Rheumatology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou; J. Wu, MD, Department of Rheumatology, The First Affiliated Hospital of Soochow University, Suzhou; Y. Lu, MD, Department of Rheumatology, Jiangsu Province Hospital of Chinese Medicine, Nanjing; D. Su, MD, Department of Rheumatology, Nanjing First Hospital, Nanjing; Z. Liu, MD, Department of Rheumatology, The Second Affiliated Hospital of Soochow University, Suzhou; L. Liu, MD, Department of Rheumatology, Xuzhou Central Hospital, Xuzhou; L. Ma, MD, Department of Rheumatology, Yancheng No.1 People's Hospital, Yancheng; X. Xu, MD, Department of Rheumatology, Zhongda Hospital Southeast University, Nanjing; Y. Zang, MD, Department of Rheumatology, The Affiliated Suqian First People's Hospital of Nanjing Medical University, Suqian; H. Liu, MD, Department of Rheumatology, The First People's Hospital of Lianyungang, Lianyungang; T. Ren, MD, Department of Rheumatology, Wuxi No.2 People's Hospital, Wuxi; F. Wang, MD, PhD, Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, China, Nanjing, Jiangsu, China. C. Lv and H. You are joint first authors and contributed equally to this manuscript. W. Tan and M. Zhang contributed equally to this manuscript. Address correspondence to Dr. W. Tan or Dr. M. Zhang, Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China. Email: tw2006@njmu.edu.cn or mjzhang@njmu.edu.cn. Accepted for publication June 2, 2022.
Fenghong Yuan
This work was supported by the National Natural Science Foundation of China (grants 81971532, 81971533, and 82071827), the Special Financial Grant from the China Postdoctoral Science Foundation (grant 2021TQ0134), the Natural Science Foundation of Jiangsu Province (grant BK20210964), and the Doctoral Program of Entrepreneurship and Innovation in Jiangsu Province (grant JSSCBS20211479). The funders had no role in the study design, the data collection and analysis, the decision to publish, or the preparation of the manuscript. C. Lv, MD, H. You, MD, PhD, L. Xu, MD, PhD, L. Wang, MD, PhD, M. Zhang, MD, W. Tan, MD, PhD, Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing; F. Yuan, MD, Department of Rheumatology and Immunology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi; J. Li, MD, Department of Rheumatology, Huai'an First People's Hospital, Huai'an, Jiangsu; M. Wu, MD, S. Zhou, MD, Department of Rheumatology, The First People's Hospital of Changzhou, Changzhou; Z. Da, MD, J. Qian, MD, Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong; H. Wei, MD, W. Yan, MD, Department of Rheumatology, Northern Jiangsu People's Hospital, Yangzhou; L. Zhou, MD, Y. Wang, MD, Department of Rheumatology, Changzhou No.2 People's Hospital, Changzhou; S. Yin, MD, D. Zhou, MD, Department of Rheumatology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou; J. Wu, MD, Department of Rheumatology, The First Affiliated Hospital of Soochow University, Suzhou; Y. Lu, MD, Department of Rheumatology, Jiangsu Province Hospital of Chinese Medicine, Nanjing; D. Su, MD, Department of Rheumatology, Nanjing First Hospital, Nanjing; Z. Liu, MD, Department of Rheumatology, The Second Affiliated Hospital of Soochow University, Suzhou; L. Liu, MD, Department of Rheumatology, Xuzhou Central Hospital, Xuzhou; L. Ma, MD, Department of Rheumatology, Yancheng No.1 People's Hospital, Yancheng; X. Xu, MD, Department of Rheumatology, Zhongda Hospital Southeast University, Nanjing; Y. Zang, MD, Department of Rheumatology, The Affiliated Suqian First People's Hospital of Nanjing Medical University, Suqian; H. Liu, MD, Department of Rheumatology, The First People's Hospital of Lianyungang, Lianyungang; T. Ren, MD, Department of Rheumatology, Wuxi No.2 People's Hospital, Wuxi; F. Wang, MD, PhD, Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, China, Nanjing, Jiangsu, China. C. Lv and H. You are joint first authors and contributed equally to this manuscript. W. Tan and M. Zhang contributed equally to this manuscript. Address correspondence to Dr. W. Tan or Dr. M. Zhang, Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China. Email: tw2006@njmu.edu.cn or mjzhang@njmu.edu.cn. Accepted for publication June 2, 2022.
Ju Li
This work was supported by the National Natural Science Foundation of China (grants 81971532, 81971533, and 82071827), the Special Financial Grant from the China Postdoctoral Science Foundation (grant 2021TQ0134), the Natural Science Foundation of Jiangsu Province (grant BK20210964), and the Doctoral Program of Entrepreneurship and Innovation in Jiangsu Province (grant JSSCBS20211479). The funders had no role in the study design, the data collection and analysis, the decision to publish, or the preparation of the manuscript. C. Lv, MD, H. You, MD, PhD, L. Xu, MD, PhD, L. Wang, MD, PhD, M. Zhang, MD, W. Tan, MD, PhD, Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing; F. Yuan, MD, Department of Rheumatology and Immunology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi; J. Li, MD, Department of Rheumatology, Huai'an First People's Hospital, Huai'an, Jiangsu; M. Wu, MD, S. Zhou, MD, Department of Rheumatology, The First People's Hospital of Changzhou, Changzhou; Z. Da, MD, J. Qian, MD, Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong; H. Wei, MD, W. Yan, MD, Department of Rheumatology, Northern Jiangsu People's Hospital, Yangzhou; L. Zhou, MD, Y. Wang, MD, Department of Rheumatology, Changzhou No.2 People's Hospital, Changzhou; S. Yin, MD, D. Zhou, MD, Department of Rheumatology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou; J. Wu, MD, Department of Rheumatology, The First Affiliated Hospital of Soochow University, Suzhou; Y. Lu, MD, Department of Rheumatology, Jiangsu Province Hospital of Chinese Medicine, Nanjing; D. Su, MD, Department of Rheumatology, Nanjing First Hospital, Nanjing; Z. Liu, MD, Department of Rheumatology, The Second Affiliated Hospital of Soochow University, Suzhou; L. Liu, MD, Department of Rheumatology, Xuzhou Central Hospital, Xuzhou; L. Ma, MD, Department of Rheumatology, Yancheng No.1 People's Hospital, Yancheng; X. Xu, MD, Department of Rheumatology, Zhongda Hospital Southeast University, Nanjing; Y. Zang, MD, Department of Rheumatology, The Affiliated Suqian First People's Hospital of Nanjing Medical University, Suqian; H. Liu, MD, Department of Rheumatology, The First People's Hospital of Lianyungang, Lianyungang; T. Ren, MD, Department of Rheumatology, Wuxi No.2 People's Hospital, Wuxi; F. Wang, MD, PhD, Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, China, Nanjing, Jiangsu, China. C. Lv and H. You are joint first authors and contributed equally to this manuscript. W. Tan and M. Zhang contributed equally to this manuscript. Address correspondence to Dr. W. Tan or Dr. M. Zhang, Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China. Email: tw2006@njmu.edu.cn or mjzhang@njmu.edu.cn. Accepted for publication June 2, 2022.
Min Wu
This work was supported by the National Natural Science Foundation of China (grants 81971532, 81971533, and 82071827), the Special Financial Grant from the China Postdoctoral Science Foundation (grant 2021TQ0134), the Natural Science Foundation of Jiangsu Province (grant BK20210964), and the Doctoral Program of Entrepreneurship and Innovation in Jiangsu Province (grant JSSCBS20211479). The funders had no role in the study design, the data collection and analysis, the decision to publish, or the preparation of the manuscript. C. Lv, MD, H. You, MD, PhD, L. Xu, MD, PhD, L. Wang, MD, PhD, M. Zhang, MD, W. Tan, MD, PhD, Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing; F. Yuan, MD, Department of Rheumatology and Immunology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi; J. Li, MD, Department of Rheumatology, Huai'an First People's Hospital, Huai'an, Jiangsu; M. Wu, MD, S. Zhou, MD, Department of Rheumatology, The First People's Hospital of Changzhou, Changzhou; Z. Da, MD, J. Qian, MD, Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong; H. Wei, MD, W. Yan, MD, Department of Rheumatology, Northern Jiangsu People's Hospital, Yangzhou; L. Zhou, MD, Y. Wang, MD, Department of Rheumatology, Changzhou No.2 People's Hospital, Changzhou; S. Yin, MD, D. Zhou, MD, Department of Rheumatology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou; J. Wu, MD, Department of Rheumatology, The First Affiliated Hospital of Soochow University, Suzhou; Y. Lu, MD, Department of Rheumatology, Jiangsu Province Hospital of Chinese Medicine, Nanjing; D. Su, MD, Department of Rheumatology, Nanjing First Hospital, Nanjing; Z. Liu, MD, Department of Rheumatology, The Second Affiliated Hospital of Soochow University, Suzhou; L. Liu, MD, Department of Rheumatology, Xuzhou Central Hospital, Xuzhou; L. Ma, MD, Department of Rheumatology, Yancheng No.1 People's Hospital, Yancheng; X. Xu, MD, Department of Rheumatology, Zhongda Hospital Southeast University, Nanjing; Y. Zang, MD, Department of Rheumatology, The Affiliated Suqian First People's Hospital of Nanjing Medical University, Suqian; H. Liu, MD, Department of Rheumatology, The First People's Hospital of Lianyungang, Lianyungang; T. Ren, MD, Department of Rheumatology, Wuxi No.2 People's Hospital, Wuxi; F. Wang, MD, PhD, Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, China, Nanjing, Jiangsu, China. C. Lv and H. You are joint first authors and contributed equally to this manuscript. W. Tan and M. Zhang contributed equally to this manuscript. Address correspondence to Dr. W. Tan or Dr. M. Zhang, Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China. Email: tw2006@njmu.edu.cn or mjzhang@njmu.edu.cn. Accepted for publication June 2, 2022.
Shiliang Zhou
This work was supported by the National Natural Science Foundation of China (grants 81971532, 81971533, and 82071827), the Special Financial Grant from the China Postdoctoral Science Foundation (grant 2021TQ0134), the Natural Science Foundation of Jiangsu Province (grant BK20210964), and the Doctoral Program of Entrepreneurship and Innovation in Jiangsu Province (grant JSSCBS20211479). The funders had no role in the study design, the data collection and analysis, the decision to publish, or the preparation of the manuscript. C. Lv, MD, H. You, MD, PhD, L. Xu, MD, PhD, L. Wang, MD, PhD, M. Zhang, MD, W. Tan, MD, PhD, Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing; F. Yuan, MD, Department of Rheumatology and Immunology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi; J. Li, MD, Department of Rheumatology, Huai'an First People's Hospital, Huai'an, Jiangsu; M. Wu, MD, S. Zhou, MD, Department of Rheumatology, The First People's Hospital of Changzhou, Changzhou; Z. Da, MD, J. Qian, MD, Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong; H. Wei, MD, W. Yan, MD, Department of Rheumatology, Northern Jiangsu People's Hospital, Yangzhou; L. Zhou, MD, Y. Wang, MD, Department of Rheumatology, Changzhou No.2 People's Hospital, Changzhou; S. Yin, MD, D. Zhou, MD, Department of Rheumatology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou; J. Wu, MD, Department of Rheumatology, The First Affiliated Hospital of Soochow University, Suzhou; Y. Lu, MD, Department of Rheumatology, Jiangsu Province Hospital of Chinese Medicine, Nanjing; D. Su, MD, Department of Rheumatology, Nanjing First Hospital, Nanjing; Z. Liu, MD, Department of Rheumatology, The Second Affiliated Hospital of Soochow University, Suzhou; L. Liu, MD, Department of Rheumatology, Xuzhou Central Hospital, Xuzhou; L. Ma, MD, Department of Rheumatology, Yancheng No.1 People's Hospital, Yancheng; X. Xu, MD, Department of Rheumatology, Zhongda Hospital Southeast University, Nanjing; Y. Zang, MD, Department of Rheumatology, The Affiliated Suqian First People's Hospital of Nanjing Medical University, Suqian; H. Liu, MD, Department of Rheumatology, The First People's Hospital of Lianyungang, Lianyungang; T. Ren, MD, Department of Rheumatology, Wuxi No.2 People's Hospital, Wuxi; F. Wang, MD, PhD, Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, China, Nanjing, Jiangsu, China. C. Lv and H. You are joint first authors and contributed equally to this manuscript. W. Tan and M. Zhang contributed equally to this manuscript. Address correspondence to Dr. W. Tan or Dr. M. Zhang, Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China. Email: tw2006@njmu.edu.cn or mjzhang@njmu.edu.cn. Accepted for publication June 2, 2022.
Zhanyun Da
This work was supported by the National Natural Science Foundation of China (grants 81971532, 81971533, and 82071827), the Special Financial Grant from the China Postdoctoral Science Foundation (grant 2021TQ0134), the Natural Science Foundation of Jiangsu Province (grant BK20210964), and the Doctoral Program of Entrepreneurship and Innovation in Jiangsu Province (grant JSSCBS20211479). The funders had no role in the study design, the data collection and analysis, the decision to publish, or the preparation of the manuscript. C. Lv, MD, H. You, MD, PhD, L. Xu, MD, PhD, L. Wang, MD, PhD, M. Zhang, MD, W. Tan, MD, PhD, Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing; F. Yuan, MD, Department of Rheumatology and Immunology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi; J. Li, MD, Department of Rheumatology, Huai'an First People's Hospital, Huai'an, Jiangsu; M. Wu, MD, S. Zhou, MD, Department of Rheumatology, The First People's Hospital of Changzhou, Changzhou; Z. Da, MD, J. Qian, MD, Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong; H. Wei, MD, W. Yan, MD, Department of Rheumatology, Northern Jiangsu People's Hospital, Yangzhou; L. Zhou, MD, Y. Wang, MD, Department of Rheumatology, Changzhou No.2 People's Hospital, Changzhou; S. Yin, MD, D. Zhou, MD, Department of Rheumatology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou; J. Wu, MD, Department of Rheumatology, The First Affiliated Hospital of Soochow University, Suzhou; Y. Lu, MD, Department of Rheumatology, Jiangsu Province Hospital of Chinese Medicine, Nanjing; D. Su, MD, Department of Rheumatology, Nanjing First Hospital, Nanjing; Z. Liu, MD, Department of Rheumatology, The Second Affiliated Hospital of Soochow University, Suzhou; L. Liu, MD, Department of Rheumatology, Xuzhou Central Hospital, Xuzhou; L. Ma, MD, Department of Rheumatology, Yancheng No.1 People's Hospital, Yancheng; X. Xu, MD, Department of Rheumatology, Zhongda Hospital Southeast University, Nanjing; Y. Zang, MD, Department of Rheumatology, The Affiliated Suqian First People's Hospital of Nanjing Medical University, Suqian; H. Liu, MD, Department of Rheumatology, The First People's Hospital of Lianyungang, Lianyungang; T. Ren, MD, Department of Rheumatology, Wuxi No.2 People's Hospital, Wuxi; F. Wang, MD, PhD, Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, China, Nanjing, Jiangsu, China. C. Lv and H. You are joint first authors and contributed equally to this manuscript. W. Tan and M. Zhang contributed equally to this manuscript. Address correspondence to Dr. W. Tan or Dr. M. Zhang, Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China. Email: tw2006@njmu.edu.cn or mjzhang@njmu.edu.cn. Accepted for publication June 2, 2022.
Jie Qian
This work was supported by the National Natural Science Foundation of China (grants 81971532, 81971533, and 82071827), the Special Financial Grant from the China Postdoctoral Science Foundation (grant 2021TQ0134), the Natural Science Foundation of Jiangsu Province (grant BK20210964), and the Doctoral Program of Entrepreneurship and Innovation in Jiangsu Province (grant JSSCBS20211479). The funders had no role in the study design, the data collection and analysis, the decision to publish, or the preparation of the manuscript. C. Lv, MD, H. You, MD, PhD, L. Xu, MD, PhD, L. Wang, MD, PhD, M. Zhang, MD, W. Tan, MD, PhD, Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing; F. Yuan, MD, Department of Rheumatology and Immunology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi; J. Li, MD, Department of Rheumatology, Huai'an First People's Hospital, Huai'an, Jiangsu; M. Wu, MD, S. Zhou, MD, Department of Rheumatology, The First People's Hospital of Changzhou, Changzhou; Z. Da, MD, J. Qian, MD, Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong; H. Wei, MD, W. Yan, MD, Department of Rheumatology, Northern Jiangsu People's Hospital, Yangzhou; L. Zhou, MD, Y. Wang, MD, Department of Rheumatology, Changzhou No.2 People's Hospital, Changzhou; S. Yin, MD, D. Zhou, MD, Department of Rheumatology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou; J. Wu, MD, Department of Rheumatology, The First Affiliated Hospital of Soochow University, Suzhou; Y. Lu, MD, Department of Rheumatology, Jiangsu Province Hospital of Chinese Medicine, Nanjing; D. Su, MD, Department of Rheumatology, Nanjing First Hospital, Nanjing; Z. Liu, MD, Department of Rheumatology, The Second Affiliated Hospital of Soochow University, Suzhou; L. Liu, MD, Department of Rheumatology, Xuzhou Central Hospital, Xuzhou; L. Ma, MD, Department of Rheumatology, Yancheng No.1 People's Hospital, Yancheng; X. Xu, MD, Department of Rheumatology, Zhongda Hospital Southeast University, Nanjing; Y. Zang, MD, Department of Rheumatology, The Affiliated Suqian First People's Hospital of Nanjing Medical University, Suqian; H. Liu, MD, Department of Rheumatology, The First People's Hospital of Lianyungang, Lianyungang; T. Ren, MD, Department of Rheumatology, Wuxi No.2 People's Hospital, Wuxi; F. Wang, MD, PhD, Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, China, Nanjing, Jiangsu, China. C. Lv and H. You are joint first authors and contributed equally to this manuscript. W. Tan and M. Zhang contributed equally to this manuscript. Address correspondence to Dr. W. Tan or Dr. M. Zhang, Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China. Email: tw2006@njmu.edu.cn or mjzhang@njmu.edu.cn. Accepted for publication June 2, 2022.
Hua Wei
This work was supported by the National Natural Science Foundation of China (grants 81971532, 81971533, and 82071827), the Special Financial Grant from the China Postdoctoral Science Foundation (grant 2021TQ0134), the Natural Science Foundation of Jiangsu Province (grant BK20210964), and the Doctoral Program of Entrepreneurship and Innovation in Jiangsu Province (grant JSSCBS20211479). The funders had no role in the study design, the data collection and analysis, the decision to publish, or the preparation of the manuscript. C. Lv, MD, H. You, MD, PhD, L. Xu, MD, PhD, L. Wang, MD, PhD, M. Zhang, MD, W. Tan, MD, PhD, Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing; F. Yuan, MD, Department of Rheumatology and Immunology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi; J. Li, MD, Department of Rheumatology, Huai'an First People's Hospital, Huai'an, Jiangsu; M. Wu, MD, S. Zhou, MD, Department of Rheumatology, The First People's Hospital of Changzhou, Changzhou; Z. Da, MD, J. Qian, MD, Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong; H. Wei, MD, W. Yan, MD, Department of Rheumatology, Northern Jiangsu People's Hospital, Yangzhou; L. Zhou, MD, Y. Wang, MD, Department of Rheumatology, Changzhou No.2 People's Hospital, Changzhou; S. Yin, MD, D. Zhou, MD, Department of Rheumatology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou; J. Wu, MD, Department of Rheumatology, The First Affiliated Hospital of Soochow University, Suzhou; Y. Lu, MD, Department of Rheumatology, Jiangsu Province Hospital of Chinese Medicine, Nanjing; D. Su, MD, Department of Rheumatology, Nanjing First Hospital, Nanjing; Z. Liu, MD, Department of Rheumatology, The Second Affiliated Hospital of Soochow University, Suzhou; L. Liu, MD, Department of Rheumatology, Xuzhou Central Hospital, Xuzhou; L. Ma, MD, Department of Rheumatology, Yancheng No.1 People's Hospital, Yancheng; X. Xu, MD, Department of Rheumatology, Zhongda Hospital Southeast University, Nanjing; Y. Zang, MD, Department of Rheumatology, The Affiliated Suqian First People's Hospital of Nanjing Medical University, Suqian; H. Liu, MD, Department of Rheumatology, The First People's Hospital of Lianyungang, Lianyungang; T. Ren, MD, Department of Rheumatology, Wuxi No.2 People's Hospital, Wuxi; F. Wang, MD, PhD, Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, China, Nanjing, Jiangsu, China. C. Lv and H. You are joint first authors and contributed equally to this manuscript. W. Tan and M. Zhang contributed equally to this manuscript. Address correspondence to Dr. W. Tan or Dr. M. Zhang, Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China. Email: tw2006@njmu.edu.cn or mjzhang@njmu.edu.cn. Accepted for publication June 2, 2022.
Wei Yan
This work was supported by the National Natural Science Foundation of China (grants 81971532, 81971533, and 82071827), the Special Financial Grant from the China Postdoctoral Science Foundation (grant 2021TQ0134), the Natural Science Foundation of Jiangsu Province (grant BK20210964), and the Doctoral Program of Entrepreneurship and Innovation in Jiangsu Province (grant JSSCBS20211479). The funders had no role in the study design, the data collection and analysis, the decision to publish, or the preparation of the manuscript. C. Lv, MD, H. You, MD, PhD, L. Xu, MD, PhD, L. Wang, MD, PhD, M. Zhang, MD, W. Tan, MD, PhD, Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing; F. Yuan, MD, Department of Rheumatology and Immunology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi; J. Li, MD, Department of Rheumatology, Huai'an First People's Hospital, Huai'an, Jiangsu; M. Wu, MD, S. Zhou, MD, Department of Rheumatology, The First People's Hospital of Changzhou, Changzhou; Z. Da, MD, J. Qian, MD, Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong; H. Wei, MD, W. Yan, MD, Department of Rheumatology, Northern Jiangsu People's Hospital, Yangzhou; L. Zhou, MD, Y. Wang, MD, Department of Rheumatology, Changzhou No.2 People's Hospital, Changzhou; S. Yin, MD, D. Zhou, MD, Department of Rheumatology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou; J. Wu, MD, Department of Rheumatology, The First Affiliated Hospital of Soochow University, Suzhou; Y. Lu, MD, Department of Rheumatology, Jiangsu Province Hospital of Chinese Medicine, Nanjing; D. Su, MD, Department of Rheumatology, Nanjing First Hospital, Nanjing; Z. Liu, MD, Department of Rheumatology, The Second Affiliated Hospital of Soochow University, Suzhou; L. Liu, MD, Department of Rheumatology, Xuzhou Central Hospital, Xuzhou; L. Ma, MD, Department of Rheumatology, Yancheng No.1 People's Hospital, Yancheng; X. Xu, MD, Department of Rheumatology, Zhongda Hospital Southeast University, Nanjing; Y. Zang, MD, Department of Rheumatology, The Affiliated Suqian First People's Hospital of Nanjing Medical University, Suqian; H. Liu, MD, Department of Rheumatology, The First People's Hospital of Lianyungang, Lianyungang; T. Ren, MD, Department of Rheumatology, Wuxi No.2 People's Hospital, Wuxi; F. Wang, MD, PhD, Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, China, Nanjing, Jiangsu, China. C. Lv and H. You are joint first authors and contributed equally to this manuscript. W. Tan and M. Zhang contributed equally to this manuscript. Address correspondence to Dr. W. Tan or Dr. M. Zhang, Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China. Email: tw2006@njmu.edu.cn or mjzhang@njmu.edu.cn. Accepted for publication June 2, 2022.
Lei Zhou
This work was supported by the National Natural Science Foundation of China (grants 81971532, 81971533, and 82071827), the Special Financial Grant from the China Postdoctoral Science Foundation (grant 2021TQ0134), the Natural Science Foundation of Jiangsu Province (grant BK20210964), and the Doctoral Program of Entrepreneurship and Innovation in Jiangsu Province (grant JSSCBS20211479). The funders had no role in the study design, the data collection and analysis, the decision to publish, or the preparation of the manuscript. C. Lv, MD, H. You, MD, PhD, L. Xu, MD, PhD, L. Wang, MD, PhD, M. Zhang, MD, W. Tan, MD, PhD, Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing; F. Yuan, MD, Department of Rheumatology and Immunology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi; J. Li, MD, Department of Rheumatology, Huai'an First People's Hospital, Huai'an, Jiangsu; M. Wu, MD, S. Zhou, MD, Department of Rheumatology, The First People's Hospital of Changzhou, Changzhou; Z. Da, MD, J. Qian, MD, Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong; H. Wei, MD, W. Yan, MD, Department of Rheumatology, Northern Jiangsu People's Hospital, Yangzhou; L. Zhou, MD, Y. Wang, MD, Department of Rheumatology, Changzhou No.2 People's Hospital, Changzhou; S. Yin, MD, D. Zhou, MD, Department of Rheumatology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou; J. Wu, MD, Department of Rheumatology, The First Affiliated Hospital of Soochow University, Suzhou; Y. Lu, MD, Department of Rheumatology, Jiangsu Province Hospital of Chinese Medicine, Nanjing; D. Su, MD, Department of Rheumatology, Nanjing First Hospital, Nanjing; Z. Liu, MD, Department of Rheumatology, The Second Affiliated Hospital of Soochow University, Suzhou; L. Liu, MD, Department of Rheumatology, Xuzhou Central Hospital, Xuzhou; L. Ma, MD, Department of Rheumatology, Yancheng No.1 People's Hospital, Yancheng; X. Xu, MD, Department of Rheumatology, Zhongda Hospital Southeast University, Nanjing; Y. Zang, MD, Department of Rheumatology, The Affiliated Suqian First People's Hospital of Nanjing Medical University, Suqian; H. Liu, MD, Department of Rheumatology, The First People's Hospital of Lianyungang, Lianyungang; T. Ren, MD, Department of Rheumatology, Wuxi No.2 People's Hospital, Wuxi; F. Wang, MD, PhD, Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, China, Nanjing, Jiangsu, China. C. Lv and H. You are joint first authors and contributed equally to this manuscript. W. Tan and M. Zhang contributed equally to this manuscript. Address correspondence to Dr. W. Tan or Dr. M. Zhang, Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China. Email: tw2006@njmu.edu.cn or mjzhang@njmu.edu.cn. Accepted for publication June 2, 2022.
Yan Wang
This work was supported by the National Natural Science Foundation of China (grants 81971532, 81971533, and 82071827), the Special Financial Grant from the China Postdoctoral Science Foundation (grant 2021TQ0134), the Natural Science Foundation of Jiangsu Province (grant BK20210964), and the Doctoral Program of Entrepreneurship and Innovation in Jiangsu Province (grant JSSCBS20211479). The funders had no role in the study design, the data collection and analysis, the decision to publish, or the preparation of the manuscript. C. Lv, MD, H. You, MD, PhD, L. Xu, MD, PhD, L. Wang, MD, PhD, M. Zhang, MD, W. Tan, MD, PhD, Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing; F. Yuan, MD, Department of Rheumatology and Immunology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi; J. Li, MD, Department of Rheumatology, Huai'an First People's Hospital, Huai'an, Jiangsu; M. Wu, MD, S. Zhou, MD, Department of Rheumatology, The First People's Hospital of Changzhou, Changzhou; Z. Da, MD, J. Qian, MD, Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong; H. Wei, MD, W. Yan, MD, Department of Rheumatology, Northern Jiangsu People's Hospital, Yangzhou; L. Zhou, MD, Y. Wang, MD, Department of Rheumatology, Changzhou No.2 People's Hospital, Changzhou; S. Yin, MD, D. Zhou, MD, Department of Rheumatology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou; J. Wu, MD, Department of Rheumatology, The First Affiliated Hospital of Soochow University, Suzhou; Y. Lu, MD, Department of Rheumatology, Jiangsu Province Hospital of Chinese Medicine, Nanjing; D. Su, MD, Department of Rheumatology, Nanjing First Hospital, Nanjing; Z. Liu, MD, Department of Rheumatology, The Second Affiliated Hospital of Soochow University, Suzhou; L. Liu, MD, Department of Rheumatology, Xuzhou Central Hospital, Xuzhou; L. Ma, MD, Department of Rheumatology, Yancheng No.1 People's Hospital, Yancheng; X. Xu, MD, Department of Rheumatology, Zhongda Hospital Southeast University, Nanjing; Y. Zang, MD, Department of Rheumatology, The Affiliated Suqian First People's Hospital of Nanjing Medical University, Suqian; H. Liu, MD, Department of Rheumatology, The First People's Hospital of Lianyungang, Lianyungang; T. Ren, MD, Department of Rheumatology, Wuxi No.2 People's Hospital, Wuxi; F. Wang, MD, PhD, Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, China, Nanjing, Jiangsu, China. C. Lv and H. You are joint first authors and contributed equally to this manuscript. W. Tan and M. Zhang contributed equally to this manuscript. Address correspondence to Dr. W. Tan or Dr. M. Zhang, Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China. Email: tw2006@njmu.edu.cn or mjzhang@njmu.edu.cn. Accepted for publication June 2, 2022.
Songlou Yin
This work was supported by the National Natural Science Foundation of China (grants 81971532, 81971533, and 82071827), the Special Financial Grant from the China Postdoctoral Science Foundation (grant 2021TQ0134), the Natural Science Foundation of Jiangsu Province (grant BK20210964), and the Doctoral Program of Entrepreneurship and Innovation in Jiangsu Province (grant JSSCBS20211479). The funders had no role in the study design, the data collection and analysis, the decision to publish, or the preparation of the manuscript. C. Lv, MD, H. You, MD, PhD, L. Xu, MD, PhD, L. Wang, MD, PhD, M. Zhang, MD, W. Tan, MD, PhD, Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing; F. Yuan, MD, Department of Rheumatology and Immunology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi; J. Li, MD, Department of Rheumatology, Huai'an First People's Hospital, Huai'an, Jiangsu; M. Wu, MD, S. Zhou, MD, Department of Rheumatology, The First People's Hospital of Changzhou, Changzhou; Z. Da, MD, J. Qian, MD, Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong; H. Wei, MD, W. Yan, MD, Department of Rheumatology, Northern Jiangsu People's Hospital, Yangzhou; L. Zhou, MD, Y. Wang, MD, Department of Rheumatology, Changzhou No.2 People's Hospital, Changzhou; S. Yin, MD, D. Zhou, MD, Department of Rheumatology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou; J. Wu, MD, Department of Rheumatology, The First Affiliated Hospital of Soochow University, Suzhou; Y. Lu, MD, Department of Rheumatology, Jiangsu Province Hospital of Chinese Medicine, Nanjing; D. Su, MD, Department of Rheumatology, Nanjing First Hospital, Nanjing; Z. Liu, MD, Department of Rheumatology, The Second Affiliated Hospital of Soochow University, Suzhou; L. Liu, MD, Department of Rheumatology, Xuzhou Central Hospital, Xuzhou; L. Ma, MD, Department of Rheumatology, Yancheng No.1 People's Hospital, Yancheng; X. Xu, MD, Department of Rheumatology, Zhongda Hospital Southeast University, Nanjing; Y. Zang, MD, Department of Rheumatology, The Affiliated Suqian First People's Hospital of Nanjing Medical University, Suqian; H. Liu, MD, Department of Rheumatology, The First People's Hospital of Lianyungang, Lianyungang; T. Ren, MD, Department of Rheumatology, Wuxi No.2 People's Hospital, Wuxi; F. Wang, MD, PhD, Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, China, Nanjing, Jiangsu, China. C. Lv and H. You are joint first authors and contributed equally to this manuscript. W. Tan and M. Zhang contributed equally to this manuscript. Address correspondence to Dr. W. Tan or Dr. M. Zhang, Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China. Email: tw2006@njmu.edu.cn or mjzhang@njmu.edu.cn. Accepted for publication June 2, 2022.
Dongmei Zhou
This work was supported by the National Natural Science Foundation of China (grants 81971532, 81971533, and 82071827), the Special Financial Grant from the China Postdoctoral Science Foundation (grant 2021TQ0134), the Natural Science Foundation of Jiangsu Province (grant BK20210964), and the Doctoral Program of Entrepreneurship and Innovation in Jiangsu Province (grant JSSCBS20211479). The funders had no role in the study design, the data collection and analysis, the decision to publish, or the preparation of the manuscript. C. Lv, MD, H. You, MD, PhD, L. Xu, MD, PhD, L. Wang, MD, PhD, M. Zhang, MD, W. Tan, MD, PhD, Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing; F. Yuan, MD, Department of Rheumatology and Immunology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi; J. Li, MD, Department of Rheumatology, Huai'an First People's Hospital, Huai'an, Jiangsu; M. Wu, MD, S. Zhou, MD, Department of Rheumatology, The First People's Hospital of Changzhou, Changzhou; Z. Da, MD, J. Qian, MD, Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong; H. Wei, MD, W. Yan, MD, Department of Rheumatology, Northern Jiangsu People's Hospital, Yangzhou; L. Zhou, MD, Y. Wang, MD, Department of Rheumatology, Changzhou No.2 People's Hospital, Changzhou; S. Yin, MD, D. Zhou, MD, Department of Rheumatology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou; J. Wu, MD, Department of Rheumatology, The First Affiliated Hospital of Soochow University, Suzhou; Y. Lu, MD, Department of Rheumatology, Jiangsu Province Hospital of Chinese Medicine, Nanjing; D. Su, MD, Department of Rheumatology, Nanjing First Hospital, Nanjing; Z. Liu, MD, Department of Rheumatology, The Second Affiliated Hospital of Soochow University, Suzhou; L. Liu, MD, Department of Rheumatology, Xuzhou Central Hospital, Xuzhou; L. Ma, MD, Department of Rheumatology, Yancheng No.1 People's Hospital, Yancheng; X. Xu, MD, Department of Rheumatology, Zhongda Hospital Southeast University, Nanjing; Y. Zang, MD, Department of Rheumatology, The Affiliated Suqian First People's Hospital of Nanjing Medical University, Suqian; H. Liu, MD, Department of Rheumatology, The First People's Hospital of Lianyungang, Lianyungang; T. Ren, MD, Department of Rheumatology, Wuxi No.2 People's Hospital, Wuxi; F. Wang, MD, PhD, Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, China, Nanjing, Jiangsu, China. C. Lv and H. You are joint first authors and contributed equally to this manuscript. W. Tan and M. Zhang contributed equally to this manuscript. Address correspondence to Dr. W. Tan or Dr. M. Zhang, Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China. Email: tw2006@njmu.edu.cn or mjzhang@njmu.edu.cn. Accepted for publication June 2, 2022.
Jian Wu
This work was supported by the National Natural Science Foundation of China (grants 81971532, 81971533, and 82071827), the Special Financial Grant from the China Postdoctoral Science Foundation (grant 2021TQ0134), the Natural Science Foundation of Jiangsu Province (grant BK20210964), and the Doctoral Program of Entrepreneurship and Innovation in Jiangsu Province (grant JSSCBS20211479). The funders had no role in the study design, the data collection and analysis, the decision to publish, or the preparation of the manuscript. C. Lv, MD, H. You, MD, PhD, L. Xu, MD, PhD, L. Wang, MD, PhD, M. Zhang, MD, W. Tan, MD, PhD, Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing; F. Yuan, MD, Department of Rheumatology and Immunology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi; J. Li, MD, Department of Rheumatology, Huai'an First People's Hospital, Huai'an, Jiangsu; M. Wu, MD, S. Zhou, MD, Department of Rheumatology, The First People's Hospital of Changzhou, Changzhou; Z. Da, MD, J. Qian, MD, Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong; H. Wei, MD, W. Yan, MD, Department of Rheumatology, Northern Jiangsu People's Hospital, Yangzhou; L. Zhou, MD, Y. Wang, MD, Department of Rheumatology, Changzhou No.2 People's Hospital, Changzhou; S. Yin, MD, D. Zhou, MD, Department of Rheumatology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou; J. Wu, MD, Department of Rheumatology, The First Affiliated Hospital of Soochow University, Suzhou; Y. Lu, MD, Department of Rheumatology, Jiangsu Province Hospital of Chinese Medicine, Nanjing; D. Su, MD, Department of Rheumatology, Nanjing First Hospital, Nanjing; Z. Liu, MD, Department of Rheumatology, The Second Affiliated Hospital of Soochow University, Suzhou; L. Liu, MD, Department of Rheumatology, Xuzhou Central Hospital, Xuzhou; L. Ma, MD, Department of Rheumatology, Yancheng No.1 People's Hospital, Yancheng; X. Xu, MD, Department of Rheumatology, Zhongda Hospital Southeast University, Nanjing; Y. Zang, MD, Department of Rheumatology, The Affiliated Suqian First People's Hospital of Nanjing Medical University, Suqian; H. Liu, MD, Department of Rheumatology, The First People's Hospital of Lianyungang, Lianyungang; T. Ren, MD, Department of Rheumatology, Wuxi No.2 People's Hospital, Wuxi; F. Wang, MD, PhD, Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, China, Nanjing, Jiangsu, China. C. Lv and H. You are joint first authors and contributed equally to this manuscript. W. Tan and M. Zhang contributed equally to this manuscript. Address correspondence to Dr. W. Tan or Dr. M. Zhang, Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China. Email: tw2006@njmu.edu.cn or mjzhang@njmu.edu.cn. Accepted for publication June 2, 2022.
Yan Lu
This work was supported by the National Natural Science Foundation of China (grants 81971532, 81971533, and 82071827), the Special Financial Grant from the China Postdoctoral Science Foundation (grant 2021TQ0134), the Natural Science Foundation of Jiangsu Province (grant BK20210964), and the Doctoral Program of Entrepreneurship and Innovation in Jiangsu Province (grant JSSCBS20211479). The funders had no role in the study design, the data collection and analysis, the decision to publish, or the preparation of the manuscript. C. Lv, MD, H. You, MD, PhD, L. Xu, MD, PhD, L. Wang, MD, PhD, M. Zhang, MD, W. Tan, MD, PhD, Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing; F. Yuan, MD, Department of Rheumatology and Immunology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi; J. Li, MD, Department of Rheumatology, Huai'an First People's Hospital, Huai'an, Jiangsu; M. Wu, MD, S. Zhou, MD, Department of Rheumatology, The First People's Hospital of Changzhou, Changzhou; Z. Da, MD, J. Qian, MD, Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong; H. Wei, MD, W. Yan, MD, Department of Rheumatology, Northern Jiangsu People's Hospital, Yangzhou; L. Zhou, MD, Y. Wang, MD, Department of Rheumatology, Changzhou No.2 People's Hospital, Changzhou; S. Yin, MD, D. Zhou, MD, Department of Rheumatology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou; J. Wu, MD, Department of Rheumatology, The First Affiliated Hospital of Soochow University, Suzhou; Y. Lu, MD, Department of Rheumatology, Jiangsu Province Hospital of Chinese Medicine, Nanjing; D. Su, MD, Department of Rheumatology, Nanjing First Hospital, Nanjing; Z. Liu, MD, Department of Rheumatology, The Second Affiliated Hospital of Soochow University, Suzhou; L. Liu, MD, Department of Rheumatology, Xuzhou Central Hospital, Xuzhou; L. Ma, MD, Department of Rheumatology, Yancheng No.1 People's Hospital, Yancheng; X. Xu, MD, Department of Rheumatology, Zhongda Hospital Southeast University, Nanjing; Y. Zang, MD, Department of Rheumatology, The Affiliated Suqian First People's Hospital of Nanjing Medical University, Suqian; H. Liu, MD, Department of Rheumatology, The First People's Hospital of Lianyungang, Lianyungang; T. Ren, MD, Department of Rheumatology, Wuxi No.2 People's Hospital, Wuxi; F. Wang, MD, PhD, Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, China, Nanjing, Jiangsu, China. C. Lv and H. You are joint first authors and contributed equally to this manuscript. W. Tan and M. Zhang contributed equally to this manuscript. Address correspondence to Dr. W. Tan or Dr. M. Zhang, Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China. Email: tw2006@njmu.edu.cn or mjzhang@njmu.edu.cn. Accepted for publication June 2, 2022.
Dinglei Su
This work was supported by the National Natural Science Foundation of China (grants 81971532, 81971533, and 82071827), the Special Financial Grant from the China Postdoctoral Science Foundation (grant 2021TQ0134), the Natural Science Foundation of Jiangsu Province (grant BK20210964), and the Doctoral Program of Entrepreneurship and Innovation in Jiangsu Province (grant JSSCBS20211479). The funders had no role in the study design, the data collection and analysis, the decision to publish, or the preparation of the manuscript. C. Lv, MD, H. You, MD, PhD, L. Xu, MD, PhD, L. Wang, MD, PhD, M. Zhang, MD, W. Tan, MD, PhD, Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing; F. Yuan, MD, Department of Rheumatology and Immunology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi; J. Li, MD, Department of Rheumatology, Huai'an First People's Hospital, Huai'an, Jiangsu; M. Wu, MD, S. Zhou, MD, Department of Rheumatology, The First People's Hospital of Changzhou, Changzhou; Z. Da, MD, J. Qian, MD, Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong; H. Wei, MD, W. Yan, MD, Department of Rheumatology, Northern Jiangsu People's Hospital, Yangzhou; L. Zhou, MD, Y. Wang, MD, Department of Rheumatology, Changzhou No.2 People's Hospital, Changzhou; S. Yin, MD, D. Zhou, MD, Department of Rheumatology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou; J. Wu, MD, Department of Rheumatology, The First Affiliated Hospital of Soochow University, Suzhou; Y. Lu, MD, Department of Rheumatology, Jiangsu Province Hospital of Chinese Medicine, Nanjing; D. Su, MD, Department of Rheumatology, Nanjing First Hospital, Nanjing; Z. Liu, MD, Department of Rheumatology, The Second Affiliated Hospital of Soochow University, Suzhou; L. Liu, MD, Department of Rheumatology, Xuzhou Central Hospital, Xuzhou; L. Ma, MD, Department of Rheumatology, Yancheng No.1 People's Hospital, Yancheng; X. Xu, MD, Department of Rheumatology, Zhongda Hospital Southeast University, Nanjing; Y. Zang, MD, Department of Rheumatology, The Affiliated Suqian First People's Hospital of Nanjing Medical University, Suqian; H. Liu, MD, Department of Rheumatology, The First People's Hospital of Lianyungang, Lianyungang; T. Ren, MD, Department of Rheumatology, Wuxi No.2 People's Hospital, Wuxi; F. Wang, MD, PhD, Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, China, Nanjing, Jiangsu, China. C. Lv and H. You are joint first authors and contributed equally to this manuscript. W. Tan and M. Zhang contributed equally to this manuscript. Address correspondence to Dr. W. Tan or Dr. M. Zhang, Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China. Email: tw2006@njmu.edu.cn or mjzhang@njmu.edu.cn. Accepted for publication June 2, 2022.
Zhichun Liu
This work was supported by the National Natural Science Foundation of China (grants 81971532, 81971533, and 82071827), the Special Financial Grant from the China Postdoctoral Science Foundation (grant 2021TQ0134), the Natural Science Foundation of Jiangsu Province (grant BK20210964), and the Doctoral Program of Entrepreneurship and Innovation in Jiangsu Province (grant JSSCBS20211479). The funders had no role in the study design, the data collection and analysis, the decision to publish, or the preparation of the manuscript. C. Lv, MD, H. You, MD, PhD, L. Xu, MD, PhD, L. Wang, MD, PhD, M. Zhang, MD, W. Tan, MD, PhD, Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing; F. Yuan, MD, Department of Rheumatology and Immunology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi; J. Li, MD, Department of Rheumatology, Huai'an First People's Hospital, Huai'an, Jiangsu; M. Wu, MD, S. Zhou, MD, Department of Rheumatology, The First People's Hospital of Changzhou, Changzhou; Z. Da, MD, J. Qian, MD, Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong; H. Wei, MD, W. Yan, MD, Department of Rheumatology, Northern Jiangsu People's Hospital, Yangzhou; L. Zhou, MD, Y. Wang, MD, Department of Rheumatology, Changzhou No.2 People's Hospital, Changzhou; S. Yin, MD, D. Zhou, MD, Department of Rheumatology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou; J. Wu, MD, Department of Rheumatology, The First Affiliated Hospital of Soochow University, Suzhou; Y. Lu, MD, Department of Rheumatology, Jiangsu Province Hospital of Chinese Medicine, Nanjing; D. Su, MD, Department of Rheumatology, Nanjing First Hospital, Nanjing; Z. Liu, MD, Department of Rheumatology, The Second Affiliated Hospital of Soochow University, Suzhou; L. Liu, MD, Department of Rheumatology, Xuzhou Central Hospital, Xuzhou; L. Ma, MD, Department of Rheumatology, Yancheng No.1 People's Hospital, Yancheng; X. Xu, MD, Department of Rheumatology, Zhongda Hospital Southeast University, Nanjing; Y. Zang, MD, Department of Rheumatology, The Affiliated Suqian First People's Hospital of Nanjing Medical University, Suqian; H. Liu, MD, Department of Rheumatology, The First People's Hospital of Lianyungang, Lianyungang; T. Ren, MD, Department of Rheumatology, Wuxi No.2 People's Hospital, Wuxi; F. Wang, MD, PhD, Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, China, Nanjing, Jiangsu, China. C. Lv and H. You are joint first authors and contributed equally to this manuscript. W. Tan and M. Zhang contributed equally to this manuscript. Address correspondence to Dr. W. Tan or Dr. M. Zhang, Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China. Email: tw2006@njmu.edu.cn or mjzhang@njmu.edu.cn. Accepted for publication June 2, 2022.
Lin Liu
This work was supported by the National Natural Science Foundation of China (grants 81971532, 81971533, and 82071827), the Special Financial Grant from the China Postdoctoral Science Foundation (grant 2021TQ0134), the Natural Science Foundation of Jiangsu Province (grant BK20210964), and the Doctoral Program of Entrepreneurship and Innovation in Jiangsu Province (grant JSSCBS20211479). The funders had no role in the study design, the data collection and analysis, the decision to publish, or the preparation of the manuscript. C. Lv, MD, H. You, MD, PhD, L. Xu, MD, PhD, L. Wang, MD, PhD, M. Zhang, MD, W. Tan, MD, PhD, Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing; F. Yuan, MD, Department of Rheumatology and Immunology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi; J. Li, MD, Department of Rheumatology, Huai'an First People's Hospital, Huai'an, Jiangsu; M. Wu, MD, S. Zhou, MD, Department of Rheumatology, The First People's Hospital of Changzhou, Changzhou; Z. Da, MD, J. Qian, MD, Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong; H. Wei, MD, W. Yan, MD, Department of Rheumatology, Northern Jiangsu People's Hospital, Yangzhou; L. Zhou, MD, Y. Wang, MD, Department of Rheumatology, Changzhou No.2 People's Hospital, Changzhou; S. Yin, MD, D. Zhou, MD, Department of Rheumatology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou; J. Wu, MD, Department of Rheumatology, The First Affiliated Hospital of Soochow University, Suzhou; Y. Lu, MD, Department of Rheumatology, Jiangsu Province Hospital of Chinese Medicine, Nanjing; D. Su, MD, Department of Rheumatology, Nanjing First Hospital, Nanjing; Z. Liu, MD, Department of Rheumatology, The Second Affiliated Hospital of Soochow University, Suzhou; L. Liu, MD, Department of Rheumatology, Xuzhou Central Hospital, Xuzhou; L. Ma, MD, Department of Rheumatology, Yancheng No.1 People's Hospital, Yancheng; X. Xu, MD, Department of Rheumatology, Zhongda Hospital Southeast University, Nanjing; Y. Zang, MD, Department of Rheumatology, The Affiliated Suqian First People's Hospital of Nanjing Medical University, Suqian; H. Liu, MD, Department of Rheumatology, The First People's Hospital of Lianyungang, Lianyungang; T. Ren, MD, Department of Rheumatology, Wuxi No.2 People's Hospital, Wuxi; F. Wang, MD, PhD, Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, China, Nanjing, Jiangsu, China. C. Lv and H. You are joint first authors and contributed equally to this manuscript. W. Tan and M. Zhang contributed equally to this manuscript. Address correspondence to Dr. W. Tan or Dr. M. Zhang, Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China. Email: tw2006@njmu.edu.cn or mjzhang@njmu.edu.cn. Accepted for publication June 2, 2022.
Longxin Ma
This work was supported by the National Natural Science Foundation of China (grants 81971532, 81971533, and 82071827), the Special Financial Grant from the China Postdoctoral Science Foundation (grant 2021TQ0134), the Natural Science Foundation of Jiangsu Province (grant BK20210964), and the Doctoral Program of Entrepreneurship and Innovation in Jiangsu Province (grant JSSCBS20211479). The funders had no role in the study design, the data collection and analysis, the decision to publish, or the preparation of the manuscript. C. Lv, MD, H. You, MD, PhD, L. Xu, MD, PhD, L. Wang, MD, PhD, M. Zhang, MD, W. Tan, MD, PhD, Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing; F. Yuan, MD, Department of Rheumatology and Immunology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi; J. Li, MD, Department of Rheumatology, Huai'an First People's Hospital, Huai'an, Jiangsu; M. Wu, MD, S. Zhou, MD, Department of Rheumatology, The First People's Hospital of Changzhou, Changzhou; Z. Da, MD, J. Qian, MD, Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong; H. Wei, MD, W. Yan, MD, Department of Rheumatology, Northern Jiangsu People's Hospital, Yangzhou; L. Zhou, MD, Y. Wang, MD, Department of Rheumatology, Changzhou No.2 People's Hospital, Changzhou; S. Yin, MD, D. Zhou, MD, Department of Rheumatology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou; J. Wu, MD, Department of Rheumatology, The First Affiliated Hospital of Soochow University, Suzhou; Y. Lu, MD, Department of Rheumatology, Jiangsu Province Hospital of Chinese Medicine, Nanjing; D. Su, MD, Department of Rheumatology, Nanjing First Hospital, Nanjing; Z. Liu, MD, Department of Rheumatology, The Second Affiliated Hospital of Soochow University, Suzhou; L. Liu, MD, Department of Rheumatology, Xuzhou Central Hospital, Xuzhou; L. Ma, MD, Department of Rheumatology, Yancheng No.1 People's Hospital, Yancheng; X. Xu, MD, Department of Rheumatology, Zhongda Hospital Southeast University, Nanjing; Y. Zang, MD, Department of Rheumatology, The Affiliated Suqian First People's Hospital of Nanjing Medical University, Suqian; H. Liu, MD, Department of Rheumatology, The First People's Hospital of Lianyungang, Lianyungang; T. Ren, MD, Department of Rheumatology, Wuxi No.2 People's Hospital, Wuxi; F. Wang, MD, PhD, Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, China, Nanjing, Jiangsu, China. C. Lv and H. You are joint first authors and contributed equally to this manuscript. W. Tan and M. Zhang contributed equally to this manuscript. Address correspondence to Dr. W. Tan or Dr. M. Zhang, Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China. Email: tw2006@njmu.edu.cn or mjzhang@njmu.edu.cn. Accepted for publication June 2, 2022.
Xiaoyan Xu
This work was supported by the National Natural Science Foundation of China (grants 81971532, 81971533, and 82071827), the Special Financial Grant from the China Postdoctoral Science Foundation (grant 2021TQ0134), the Natural Science Foundation of Jiangsu Province (grant BK20210964), and the Doctoral Program of Entrepreneurship and Innovation in Jiangsu Province (grant JSSCBS20211479). The funders had no role in the study design, the data collection and analysis, the decision to publish, or the preparation of the manuscript. C. Lv, MD, H. You, MD, PhD, L. Xu, MD, PhD, L. Wang, MD, PhD, M. Zhang, MD, W. Tan, MD, PhD, Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing; F. Yuan, MD, Department of Rheumatology and Immunology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi; J. Li, MD, Department of Rheumatology, Huai'an First People's Hospital, Huai'an, Jiangsu; M. Wu, MD, S. Zhou, MD, Department of Rheumatology, The First People's Hospital of Changzhou, Changzhou; Z. Da, MD, J. Qian, MD, Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong; H. Wei, MD, W. Yan, MD, Department of Rheumatology, Northern Jiangsu People's Hospital, Yangzhou; L. Zhou, MD, Y. Wang, MD, Department of Rheumatology, Changzhou No.2 People's Hospital, Changzhou; S. Yin, MD, D. Zhou, MD, Department of Rheumatology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou; J. Wu, MD, Department of Rheumatology, The First Affiliated Hospital of Soochow University, Suzhou; Y. Lu, MD, Department of Rheumatology, Jiangsu Province Hospital of Chinese Medicine, Nanjing; D. Su, MD, Department of Rheumatology, Nanjing First Hospital, Nanjing; Z. Liu, MD, Department of Rheumatology, The Second Affiliated Hospital of Soochow University, Suzhou; L. Liu, MD, Department of Rheumatology, Xuzhou Central Hospital, Xuzhou; L. Ma, MD, Department of Rheumatology, Yancheng No.1 People's Hospital, Yancheng; X. Xu, MD, Department of Rheumatology, Zhongda Hospital Southeast University, Nanjing; Y. Zang, MD, Department of Rheumatology, The Affiliated Suqian First People's Hospital of Nanjing Medical University, Suqian; H. Liu, MD, Department of Rheumatology, The First People's Hospital of Lianyungang, Lianyungang; T. Ren, MD, Department of Rheumatology, Wuxi No.2 People's Hospital, Wuxi; F. Wang, MD, PhD, Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, China, Nanjing, Jiangsu, China. C. Lv and H. You are joint first authors and contributed equally to this manuscript. W. Tan and M. Zhang contributed equally to this manuscript. Address correspondence to Dr. W. Tan or Dr. M. Zhang, Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China. Email: tw2006@njmu.edu.cn or mjzhang@njmu.edu.cn. Accepted for publication June 2, 2022.
Yinshan Zang
This work was supported by the National Natural Science Foundation of China (grants 81971532, 81971533, and 82071827), the Special Financial Grant from the China Postdoctoral Science Foundation (grant 2021TQ0134), the Natural Science Foundation of Jiangsu Province (grant BK20210964), and the Doctoral Program of Entrepreneurship and Innovation in Jiangsu Province (grant JSSCBS20211479). The funders had no role in the study design, the data collection and analysis, the decision to publish, or the preparation of the manuscript. C. Lv, MD, H. You, MD, PhD, L. Xu, MD, PhD, L. Wang, MD, PhD, M. Zhang, MD, W. Tan, MD, PhD, Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing; F. Yuan, MD, Department of Rheumatology and Immunology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi; J. Li, MD, Department of Rheumatology, Huai'an First People's Hospital, Huai'an, Jiangsu; M. Wu, MD, S. Zhou, MD, Department of Rheumatology, The First People's Hospital of Changzhou, Changzhou; Z. Da, MD, J. Qian, MD, Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong; H. Wei, MD, W. Yan, MD, Department of Rheumatology, Northern Jiangsu People's Hospital, Yangzhou; L. Zhou, MD, Y. Wang, MD, Department of Rheumatology, Changzhou No.2 People's Hospital, Changzhou; S. Yin, MD, D. Zhou, MD, Department of Rheumatology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou; J. Wu, MD, Department of Rheumatology, The First Affiliated Hospital of Soochow University, Suzhou; Y. Lu, MD, Department of Rheumatology, Jiangsu Province Hospital of Chinese Medicine, Nanjing; D. Su, MD, Department of Rheumatology, Nanjing First Hospital, Nanjing; Z. Liu, MD, Department of Rheumatology, The Second Affiliated Hospital of Soochow University, Suzhou; L. Liu, MD, Department of Rheumatology, Xuzhou Central Hospital, Xuzhou; L. Ma, MD, Department of Rheumatology, Yancheng No.1 People's Hospital, Yancheng; X. Xu, MD, Department of Rheumatology, Zhongda Hospital Southeast University, Nanjing; Y. Zang, MD, Department of Rheumatology, The Affiliated Suqian First People's Hospital of Nanjing Medical University, Suqian; H. Liu, MD, Department of Rheumatology, The First People's Hospital of Lianyungang, Lianyungang; T. Ren, MD, Department of Rheumatology, Wuxi No.2 People's Hospital, Wuxi; F. Wang, MD, PhD, Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, China, Nanjing, Jiangsu, China. C. Lv and H. You are joint first authors and contributed equally to this manuscript. W. Tan and M. Zhang contributed equally to this manuscript. Address correspondence to Dr. W. Tan or Dr. M. Zhang, Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China. Email: tw2006@njmu.edu.cn or mjzhang@njmu.edu.cn. Accepted for publication June 2, 2022.
Huijie Liu
This work was supported by the National Natural Science Foundation of China (grants 81971532, 81971533, and 82071827), the Special Financial Grant from the China Postdoctoral Science Foundation (grant 2021TQ0134), the Natural Science Foundation of Jiangsu Province (grant BK20210964), and the Doctoral Program of Entrepreneurship and Innovation in Jiangsu Province (grant JSSCBS20211479). The funders had no role in the study design, the data collection and analysis, the decision to publish, or the preparation of the manuscript. C. Lv, MD, H. You, MD, PhD, L. Xu, MD, PhD, L. Wang, MD, PhD, M. Zhang, MD, W. Tan, MD, PhD, Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing; F. Yuan, MD, Department of Rheumatology and Immunology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi; J. Li, MD, Department of Rheumatology, Huai'an First People's Hospital, Huai'an, Jiangsu; M. Wu, MD, S. Zhou, MD, Department of Rheumatology, The First People's Hospital of Changzhou, Changzhou; Z. Da, MD, J. Qian, MD, Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong; H. Wei, MD, W. Yan, MD, Department of Rheumatology, Northern Jiangsu People's Hospital, Yangzhou; L. Zhou, MD, Y. Wang, MD, Department of Rheumatology, Changzhou No.2 People's Hospital, Changzhou; S. Yin, MD, D. Zhou, MD, Department of Rheumatology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou; J. Wu, MD, Department of Rheumatology, The First Affiliated Hospital of Soochow University, Suzhou; Y. Lu, MD, Department of Rheumatology, Jiangsu Province Hospital of Chinese Medicine, Nanjing; D. Su, MD, Department of Rheumatology, Nanjing First Hospital, Nanjing; Z. Liu, MD, Department of Rheumatology, The Second Affiliated Hospital of Soochow University, Suzhou; L. Liu, MD, Department of Rheumatology, Xuzhou Central Hospital, Xuzhou; L. Ma, MD, Department of Rheumatology, Yancheng No.1 People's Hospital, Yancheng; X. Xu, MD, Department of Rheumatology, Zhongda Hospital Southeast University, Nanjing; Y. Zang, MD, Department of Rheumatology, The Affiliated Suqian First People's Hospital of Nanjing Medical University, Suqian; H. Liu, MD, Department of Rheumatology, The First People's Hospital of Lianyungang, Lianyungang; T. Ren, MD, Department of Rheumatology, Wuxi No.2 People's Hospital, Wuxi; F. Wang, MD, PhD, Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, China, Nanjing, Jiangsu, China. C. Lv and H. You are joint first authors and contributed equally to this manuscript. W. Tan and M. Zhang contributed equally to this manuscript. Address correspondence to Dr. W. Tan or Dr. M. Zhang, Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China. Email: tw2006@njmu.edu.cn or mjzhang@njmu.edu.cn. Accepted for publication June 2, 2022.
Tianli Ren
This work was supported by the National Natural Science Foundation of China (grants 81971532, 81971533, and 82071827), the Special Financial Grant from the China Postdoctoral Science Foundation (grant 2021TQ0134), the Natural Science Foundation of Jiangsu Province (grant BK20210964), and the Doctoral Program of Entrepreneurship and Innovation in Jiangsu Province (grant JSSCBS20211479). The funders had no role in the study design, the data collection and analysis, the decision to publish, or the preparation of the manuscript. C. Lv, MD, H. You, MD, PhD, L. Xu, MD, PhD, L. Wang, MD, PhD, M. Zhang, MD, W. Tan, MD, PhD, Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing; F. Yuan, MD, Department of Rheumatology and Immunology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi; J. Li, MD, Department of Rheumatology, Huai'an First People's Hospital, Huai'an, Jiangsu; M. Wu, MD, S. Zhou, MD, Department of Rheumatology, The First People's Hospital of Changzhou, Changzhou; Z. Da, MD, J. Qian, MD, Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong; H. Wei, MD, W. Yan, MD, Department of Rheumatology, Northern Jiangsu People's Hospital, Yangzhou; L. Zhou, MD, Y. Wang, MD, Department of Rheumatology, Changzhou No.2 People's Hospital, Changzhou; S. Yin, MD, D. Zhou, MD, Department of Rheumatology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou; J. Wu, MD, Department of Rheumatology, The First Affiliated Hospital of Soochow University, Suzhou; Y. Lu, MD, Department of Rheumatology, Jiangsu Province Hospital of Chinese Medicine, Nanjing; D. Su, MD, Department of Rheumatology, Nanjing First Hospital, Nanjing; Z. Liu, MD, Department of Rheumatology, The Second Affiliated Hospital of Soochow University, Suzhou; L. Liu, MD, Department of Rheumatology, Xuzhou Central Hospital, Xuzhou; L. Ma, MD, Department of Rheumatology, Yancheng No.1 People's Hospital, Yancheng; X. Xu, MD, Department of Rheumatology, Zhongda Hospital Southeast University, Nanjing; Y. Zang, MD, Department of Rheumatology, The Affiliated Suqian First People's Hospital of Nanjing Medical University, Suqian; H. Liu, MD, Department of Rheumatology, The First People's Hospital of Lianyungang, Lianyungang; T. Ren, MD, Department of Rheumatology, Wuxi No.2 People's Hospital, Wuxi; F. Wang, MD, PhD, Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, China, Nanjing, Jiangsu, China. C. Lv and H. You are joint first authors and contributed equally to this manuscript. W. Tan and M. Zhang contributed equally to this manuscript. Address correspondence to Dr. W. Tan or Dr. M. Zhang, Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China. Email: tw2006@njmu.edu.cn or mjzhang@njmu.edu.cn. Accepted for publication June 2, 2022.
Fang Wang
This work was supported by the National Natural Science Foundation of China (grants 81971532, 81971533, and 82071827), the Special Financial Grant from the China Postdoctoral Science Foundation (grant 2021TQ0134), the Natural Science Foundation of Jiangsu Province (grant BK20210964), and the Doctoral Program of Entrepreneurship and Innovation in Jiangsu Province (grant JSSCBS20211479). The funders had no role in the study design, the data collection and analysis, the decision to publish, or the preparation of the manuscript. C. Lv, MD, H. You, MD, PhD, L. Xu, MD, PhD, L. Wang, MD, PhD, M. Zhang, MD, W. Tan, MD, PhD, Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing; F. Yuan, MD, Department of Rheumatology and Immunology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi; J. Li, MD, Department of Rheumatology, Huai'an First People's Hospital, Huai'an, Jiangsu; M. Wu, MD, S. Zhou, MD, Department of Rheumatology, The First People's Hospital of Changzhou, Changzhou; Z. Da, MD, J. Qian, MD, Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong; H. Wei, MD, W. Yan, MD, Department of Rheumatology, Northern Jiangsu People's Hospital, Yangzhou; L. Zhou, MD, Y. Wang, MD, Department of Rheumatology, Changzhou No.2 People's Hospital, Changzhou; S. Yin, MD, D. Zhou, MD, Department of Rheumatology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou; J. Wu, MD, Department of Rheumatology, The First Affiliated Hospital of Soochow University, Suzhou; Y. Lu, MD, Department of Rheumatology, Jiangsu Province Hospital of Chinese Medicine, Nanjing; D. Su, MD, Department of Rheumatology, Nanjing First Hospital, Nanjing; Z. Liu, MD, Department of Rheumatology, The Second Affiliated Hospital of Soochow University, Suzhou; L. Liu, MD, Department of Rheumatology, Xuzhou Central Hospital, Xuzhou; L. Ma, MD, Department of Rheumatology, Yancheng No.1 People's Hospital, Yancheng; X. Xu, MD, Department of Rheumatology, Zhongda Hospital Southeast University, Nanjing; Y. Zang, MD, Department of Rheumatology, The Affiliated Suqian First People's Hospital of Nanjing Medical University, Suqian; H. Liu, MD, Department of Rheumatology, The First People's Hospital of Lianyungang, Lianyungang; T. Ren, MD, Department of Rheumatology, Wuxi No.2 People's Hospital, Wuxi; F. Wang, MD, PhD, Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, China, Nanjing, Jiangsu, China. C. Lv and H. You are joint first authors and contributed equally to this manuscript. W. Tan and M. Zhang contributed equally to this manuscript. Address correspondence to Dr. W. Tan or Dr. M. Zhang, Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China. Email: tw2006@njmu.edu.cn or mjzhang@njmu.edu.cn. Accepted for publication June 2, 2022.
Miaojia Zhang
This work was supported by the National Natural Science Foundation of China (grants 81971532, 81971533, and 82071827), the Special Financial Grant from the China Postdoctoral Science Foundation (grant 2021TQ0134), the Natural Science Foundation of Jiangsu Province (grant BK20210964), and the Doctoral Program of Entrepreneurship and Innovation in Jiangsu Province (grant JSSCBS20211479). The funders had no role in the study design, the data collection and analysis, the decision to publish, or the preparation of the manuscript. C. Lv, MD, H. You, MD, PhD, L. Xu, MD, PhD, L. Wang, MD, PhD, M. Zhang, MD, W. Tan, MD, PhD, Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing; F. Yuan, MD, Department of Rheumatology and Immunology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi; J. Li, MD, Department of Rheumatology, Huai'an First People's Hospital, Huai'an, Jiangsu; M. Wu, MD, S. Zhou, MD, Department of Rheumatology, The First People's Hospital of Changzhou, Changzhou; Z. Da, MD, J. Qian, MD, Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong; H. Wei, MD, W. Yan, MD, Department of Rheumatology, Northern Jiangsu People's Hospital, Yangzhou; L. Zhou, MD, Y. Wang, MD, Department of Rheumatology, Changzhou No.2 People's Hospital, Changzhou; S. Yin, MD, D. Zhou, MD, Department of Rheumatology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou; J. Wu, MD, Department of Rheumatology, The First Affiliated Hospital of Soochow University, Suzhou; Y. Lu, MD, Department of Rheumatology, Jiangsu Province Hospital of Chinese Medicine, Nanjing; D. Su, MD, Department of Rheumatology, Nanjing First Hospital, Nanjing; Z. Liu, MD, Department of Rheumatology, The Second Affiliated Hospital of Soochow University, Suzhou; L. Liu, MD, Department of Rheumatology, Xuzhou Central Hospital, Xuzhou; L. Ma, MD, Department of Rheumatology, Yancheng No.1 People's Hospital, Yancheng; X. Xu, MD, Department of Rheumatology, Zhongda Hospital Southeast University, Nanjing; Y. Zang, MD, Department of Rheumatology, The Affiliated Suqian First People's Hospital of Nanjing Medical University, Suqian; H. Liu, MD, Department of Rheumatology, The First People's Hospital of Lianyungang, Lianyungang; T. Ren, MD, Department of Rheumatology, Wuxi No.2 People's Hospital, Wuxi; F. Wang, MD, PhD, Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, China, Nanjing, Jiangsu, China. C. Lv and H. You are joint first authors and contributed equally to this manuscript. W. Tan and M. Zhang contributed equally to this manuscript. Address correspondence to Dr. W. Tan or Dr. M. Zhang, Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China. Email: tw2006@njmu.edu.cn or mjzhang@njmu.edu.cn. Accepted for publication June 2, 2022.
Wenfeng Tan
This work was supported by the National Natural Science Foundation of China (grants 81971532, 81971533, and 82071827), the Special Financial Grant from the China Postdoctoral Science Foundation (grant 2021TQ0134), the Natural Science Foundation of Jiangsu Province (grant BK20210964), and the Doctoral Program of Entrepreneurship and Innovation in Jiangsu Province (grant JSSCBS20211479). The funders had no role in the study design, the data collection and analysis, the decision to publish, or the preparation of the manuscript. C. Lv, MD, H. You, MD, PhD, L. Xu, MD, PhD, L. Wang, MD, PhD, M. Zhang, MD, W. Tan, MD, PhD, Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing; F. Yuan, MD, Department of Rheumatology and Immunology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi; J. Li, MD, Department of Rheumatology, Huai'an First People's Hospital, Huai'an, Jiangsu; M. Wu, MD, S. Zhou, MD, Department of Rheumatology, The First People's Hospital of Changzhou, Changzhou; Z. Da, MD, J. Qian, MD, Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong; H. Wei, MD, W. Yan, MD, Department of Rheumatology, Northern Jiangsu People's Hospital, Yangzhou; L. Zhou, MD, Y. Wang, MD, Department of Rheumatology, Changzhou No.2 People's Hospital, Changzhou; S. Yin, MD, D. Zhou, MD, Department of Rheumatology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou; J. Wu, MD, Department of Rheumatology, The First Affiliated Hospital of Soochow University, Suzhou; Y. Lu, MD, Department of Rheumatology, Jiangsu Province Hospital of Chinese Medicine, Nanjing; D. Su, MD, Department of Rheumatology, Nanjing First Hospital, Nanjing; Z. Liu, MD, Department of Rheumatology, The Second Affiliated Hospital of Soochow University, Suzhou; L. Liu, MD, Department of Rheumatology, Xuzhou Central Hospital, Xuzhou; L. Ma, MD, Department of Rheumatology, Yancheng No.1 People's Hospital, Yancheng; X. Xu, MD, Department of Rheumatology, Zhongda Hospital Southeast University, Nanjing; Y. Zang, MD, Department of Rheumatology, The Affiliated Suqian First People's Hospital of Nanjing Medical University, Suqian; H. Liu, MD, Department of Rheumatology, The First People's Hospital of Lianyungang, Lianyungang; T. Ren, MD, Department of Rheumatology, Wuxi No.2 People's Hospital, Wuxi; F. Wang, MD, PhD, Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, China, Nanjing, Jiangsu, China. C. Lv and H. You are joint first authors and contributed equally to this manuscript. W. Tan and M. Zhang contributed equally to this manuscript. Address correspondence to Dr. W. Tan or Dr. M. Zhang, Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China. Email: tw2006@njmu.edu.cn or mjzhang@njmu.edu.cn. Accepted for publication June 2, 2022.
In this issue
The Journal of Rheumatology
Vol. 50, Issue 3
1 Mar 2023
Coexistence of Anti-Ro52 Antibodies in Anti-MDA5 Antibody–Positive Dermatomyositis Is Highly Associated With Rapidly Progressive Interstitial Lung Disease and Mortality Risk
Chengyin Lv, Hanxiao You, Lingxiao Xu, Lei Wang, Fenghong Yuan, Ju Li, Min Wu, Shiliang Zhou, Zhanyun Da, Jie Qian, Hua Wei, Wei Yan, Lei Zhou, Yan Wang, Songlou Yin, Dongmei Zhou, Jian Wu, Yan Lu, Dinglei Su, Zhichun Liu, Lin Liu, Longxin Ma, Xiaoyan Xu, Yinshan Zang, Huijie Liu, Tianli Ren, Fang Wang, Miaojia Zhang, Wenfeng Tan
The Journal of Rheumatology Jun 2022, jrheum.220139; DOI: 10.3899/jrheum.220139
Coexistence of Anti-Ro52 Antibodies in Anti-MDA5 Antibody–Positive Dermatomyositis Is Highly Associated With Rapidly Progressive Interstitial Lung Disease and Mortality Risk
Chengyin Lv, Hanxiao You, Lingxiao Xu, Lei Wang, Fenghong Yuan, Ju Li, Min Wu, Shiliang Zhou, Zhanyun Da, Jie Qian, Hua Wei, Wei Yan, Lei Zhou, Yan Wang, Songlou Yin, Dongmei Zhou, Jian Wu, Yan Lu, Dinglei Su, Zhichun Liu, Lin Liu, Longxin Ma, Xiaoyan Xu, Yinshan Zang, Huijie Liu, Tianli Ren, Fang Wang, Miaojia Zhang, Wenfeng Tan
The Journal of Rheumatology Jun 2022, jrheum.220139; DOI: 10.3899/jrheum.220139
