Research ArticleArticle
Open Access
COVID-19 vaccine uptake among patients with systemic lupus erythematosus in the American Midwest: The Lupus Midwest Network (LUMEN)
Baptiste Chevet, Gabriel Figueroa-Parra, Jeffrey X. Yang, Cassondra A. Hulshizer, Tina M. Gunderson, Stephanie Q. Duong, Michael S. Putman, Kamil E. Barbour, Cynthia S. Crowson and Alí Duarte-García
The Journal of Rheumatology July 2022, jrheum.220220; DOI: https://doi.org/10.3899/jrheum.220220
Baptiste Chevet
Funding Information: The Lupus Midwest Network (LUMEN) project is supported by the Centers for Disease Control and Prevention of the U.S. Department of Health and Human Services (HHS) under Grant number U01 DP006491 as part of a financial assistance award totaling $1,750,000 with 100 percent funded by CDC/HHS. The contents are those of the author(s) and do not necessarily represent the official views of, nor an endorsement, by CDC/HHS, or the U.S. Government. The Rochester Epidemiology Project was supported by the National Institute on Aging of the National Institutes of Health under Award Number R01AG034676, and Grant Number UL1 TR002377 from the National Center for Advancing Translational Sciences (NCATS), a component of the National Institutes of Health. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. CDC Disclaimer: The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the CDC. B. Chevet, MD, Division of Rheumatology, Mayo Clinic, Rochester, Minnesota, USA. Division of Rheumatology, Brest Teaching Hospital, LBAI, UMR1227, Univ Brest, Inserm, CHU de Brest, Brest, France. G. Figueroa-Parra, MD, Division of Rheumatology, Mayo Clinic, Rochester, Minnesota, USA. J.X. Yang, MD, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA. C.A. Hulshizer, BA, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA. T.M. Gunderson, MS, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA. S.Q. Duong, MS, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA. M.S. Putman, MD, MSci, Division of Rheumatology, Department of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin, USA. K.E. Barbour, PhD, MPH, MS, Division of Population Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia, USA. C.S. Crowson, PhD, Division of Rheumatology, Mayo Clinic, Rochester, Minnesota, USA, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA. Alí Duarte- García, MD, MSc, Division of Rheumatology, Mayo Clinic, Rochester, Minnesota, USA, Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, Minnesota, USA. Corresponding author: Alí Duarte-García MD, MSc, Mayo Clinic, 200 First Street SW, Rochester, MN 55905. Email: duarte.ali@mayo.edu
Gabriel Figueroa-Parra
Funding Information: The Lupus Midwest Network (LUMEN) project is supported by the Centers for Disease Control and Prevention of the U.S. Department of Health and Human Services (HHS) under Grant number U01 DP006491 as part of a financial assistance award totaling $1,750,000 with 100 percent funded by CDC/HHS. The contents are those of the author(s) and do not necessarily represent the official views of, nor an endorsement, by CDC/HHS, or the U.S. Government. The Rochester Epidemiology Project was supported by the National Institute on Aging of the National Institutes of Health under Award Number R01AG034676, and Grant Number UL1 TR002377 from the National Center for Advancing Translational Sciences (NCATS), a component of the National Institutes of Health. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. CDC Disclaimer: The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the CDC. B. Chevet, MD, Division of Rheumatology, Mayo Clinic, Rochester, Minnesota, USA. Division of Rheumatology, Brest Teaching Hospital, LBAI, UMR1227, Univ Brest, Inserm, CHU de Brest, Brest, France. G. Figueroa-Parra, MD, Division of Rheumatology, Mayo Clinic, Rochester, Minnesota, USA. J.X. Yang, MD, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA. C.A. Hulshizer, BA, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA. T.M. Gunderson, MS, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA. S.Q. Duong, MS, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA. M.S. Putman, MD, MSci, Division of Rheumatology, Department of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin, USA. K.E. Barbour, PhD, MPH, MS, Division of Population Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia, USA. C.S. Crowson, PhD, Division of Rheumatology, Mayo Clinic, Rochester, Minnesota, USA, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA. Alí Duarte- García, MD, MSc, Division of Rheumatology, Mayo Clinic, Rochester, Minnesota, USA, Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, Minnesota, USA. Corresponding author: Alí Duarte-García MD, MSc, Mayo Clinic, 200 First Street SW, Rochester, MN 55905. Email: duarte.ali@mayo.edu
Jeffrey X. Yang
Funding Information: The Lupus Midwest Network (LUMEN) project is supported by the Centers for Disease Control and Prevention of the U.S. Department of Health and Human Services (HHS) under Grant number U01 DP006491 as part of a financial assistance award totaling $1,750,000 with 100 percent funded by CDC/HHS. The contents are those of the author(s) and do not necessarily represent the official views of, nor an endorsement, by CDC/HHS, or the U.S. Government. The Rochester Epidemiology Project was supported by the National Institute on Aging of the National Institutes of Health under Award Number R01AG034676, and Grant Number UL1 TR002377 from the National Center for Advancing Translational Sciences (NCATS), a component of the National Institutes of Health. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. CDC Disclaimer: The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the CDC. B. Chevet, MD, Division of Rheumatology, Mayo Clinic, Rochester, Minnesota, USA. Division of Rheumatology, Brest Teaching Hospital, LBAI, UMR1227, Univ Brest, Inserm, CHU de Brest, Brest, France. G. Figueroa-Parra, MD, Division of Rheumatology, Mayo Clinic, Rochester, Minnesota, USA. J.X. Yang, MD, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA. C.A. Hulshizer, BA, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA. T.M. Gunderson, MS, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA. S.Q. Duong, MS, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA. M.S. Putman, MD, MSci, Division of Rheumatology, Department of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin, USA. K.E. Barbour, PhD, MPH, MS, Division of Population Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia, USA. C.S. Crowson, PhD, Division of Rheumatology, Mayo Clinic, Rochester, Minnesota, USA, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA. Alí Duarte- García, MD, MSc, Division of Rheumatology, Mayo Clinic, Rochester, Minnesota, USA, Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, Minnesota, USA. Corresponding author: Alí Duarte-García MD, MSc, Mayo Clinic, 200 First Street SW, Rochester, MN 55905. Email: duarte.ali@mayo.edu
Cassondra A. Hulshizer
Funding Information: The Lupus Midwest Network (LUMEN) project is supported by the Centers for Disease Control and Prevention of the U.S. Department of Health and Human Services (HHS) under Grant number U01 DP006491 as part of a financial assistance award totaling $1,750,000 with 100 percent funded by CDC/HHS. The contents are those of the author(s) and do not necessarily represent the official views of, nor an endorsement, by CDC/HHS, or the U.S. Government. The Rochester Epidemiology Project was supported by the National Institute on Aging of the National Institutes of Health under Award Number R01AG034676, and Grant Number UL1 TR002377 from the National Center for Advancing Translational Sciences (NCATS), a component of the National Institutes of Health. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. CDC Disclaimer: The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the CDC. B. Chevet, MD, Division of Rheumatology, Mayo Clinic, Rochester, Minnesota, USA. Division of Rheumatology, Brest Teaching Hospital, LBAI, UMR1227, Univ Brest, Inserm, CHU de Brest, Brest, France. G. Figueroa-Parra, MD, Division of Rheumatology, Mayo Clinic, Rochester, Minnesota, USA. J.X. Yang, MD, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA. C.A. Hulshizer, BA, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA. T.M. Gunderson, MS, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA. S.Q. Duong, MS, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA. M.S. Putman, MD, MSci, Division of Rheumatology, Department of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin, USA. K.E. Barbour, PhD, MPH, MS, Division of Population Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia, USA. C.S. Crowson, PhD, Division of Rheumatology, Mayo Clinic, Rochester, Minnesota, USA, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA. Alí Duarte- García, MD, MSc, Division of Rheumatology, Mayo Clinic, Rochester, Minnesota, USA, Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, Minnesota, USA. Corresponding author: Alí Duarte-García MD, MSc, Mayo Clinic, 200 First Street SW, Rochester, MN 55905. Email: duarte.ali@mayo.edu
Tina M. Gunderson
Funding Information: The Lupus Midwest Network (LUMEN) project is supported by the Centers for Disease Control and Prevention of the U.S. Department of Health and Human Services (HHS) under Grant number U01 DP006491 as part of a financial assistance award totaling $1,750,000 with 100 percent funded by CDC/HHS. The contents are those of the author(s) and do not necessarily represent the official views of, nor an endorsement, by CDC/HHS, or the U.S. Government. The Rochester Epidemiology Project was supported by the National Institute on Aging of the National Institutes of Health under Award Number R01AG034676, and Grant Number UL1 TR002377 from the National Center for Advancing Translational Sciences (NCATS), a component of the National Institutes of Health. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. CDC Disclaimer: The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the CDC. B. Chevet, MD, Division of Rheumatology, Mayo Clinic, Rochester, Minnesota, USA. Division of Rheumatology, Brest Teaching Hospital, LBAI, UMR1227, Univ Brest, Inserm, CHU de Brest, Brest, France. G. Figueroa-Parra, MD, Division of Rheumatology, Mayo Clinic, Rochester, Minnesota, USA. J.X. Yang, MD, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA. C.A. Hulshizer, BA, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA. T.M. Gunderson, MS, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA. S.Q. Duong, MS, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA. M.S. Putman, MD, MSci, Division of Rheumatology, Department of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin, USA. K.E. Barbour, PhD, MPH, MS, Division of Population Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia, USA. C.S. Crowson, PhD, Division of Rheumatology, Mayo Clinic, Rochester, Minnesota, USA, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA. Alí Duarte- García, MD, MSc, Division of Rheumatology, Mayo Clinic, Rochester, Minnesota, USA, Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, Minnesota, USA. Corresponding author: Alí Duarte-García MD, MSc, Mayo Clinic, 200 First Street SW, Rochester, MN 55905. Email: duarte.ali@mayo.edu
Stephanie Q. Duong
Funding Information: The Lupus Midwest Network (LUMEN) project is supported by the Centers for Disease Control and Prevention of the U.S. Department of Health and Human Services (HHS) under Grant number U01 DP006491 as part of a financial assistance award totaling $1,750,000 with 100 percent funded by CDC/HHS. The contents are those of the author(s) and do not necessarily represent the official views of, nor an endorsement, by CDC/HHS, or the U.S. Government. The Rochester Epidemiology Project was supported by the National Institute on Aging of the National Institutes of Health under Award Number R01AG034676, and Grant Number UL1 TR002377 from the National Center for Advancing Translational Sciences (NCATS), a component of the National Institutes of Health. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. CDC Disclaimer: The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the CDC. B. Chevet, MD, Division of Rheumatology, Mayo Clinic, Rochester, Minnesota, USA. Division of Rheumatology, Brest Teaching Hospital, LBAI, UMR1227, Univ Brest, Inserm, CHU de Brest, Brest, France. G. Figueroa-Parra, MD, Division of Rheumatology, Mayo Clinic, Rochester, Minnesota, USA. J.X. Yang, MD, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA. C.A. Hulshizer, BA, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA. T.M. Gunderson, MS, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA. S.Q. Duong, MS, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA. M.S. Putman, MD, MSci, Division of Rheumatology, Department of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin, USA. K.E. Barbour, PhD, MPH, MS, Division of Population Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia, USA. C.S. Crowson, PhD, Division of Rheumatology, Mayo Clinic, Rochester, Minnesota, USA, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA. Alí Duarte- García, MD, MSc, Division of Rheumatology, Mayo Clinic, Rochester, Minnesota, USA, Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, Minnesota, USA. Corresponding author: Alí Duarte-García MD, MSc, Mayo Clinic, 200 First Street SW, Rochester, MN 55905. Email: duarte.ali@mayo.edu
Michael S. Putman
Funding Information: The Lupus Midwest Network (LUMEN) project is supported by the Centers for Disease Control and Prevention of the U.S. Department of Health and Human Services (HHS) under Grant number U01 DP006491 as part of a financial assistance award totaling $1,750,000 with 100 percent funded by CDC/HHS. The contents are those of the author(s) and do not necessarily represent the official views of, nor an endorsement, by CDC/HHS, or the U.S. Government. The Rochester Epidemiology Project was supported by the National Institute on Aging of the National Institutes of Health under Award Number R01AG034676, and Grant Number UL1 TR002377 from the National Center for Advancing Translational Sciences (NCATS), a component of the National Institutes of Health. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. CDC Disclaimer: The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the CDC. B. Chevet, MD, Division of Rheumatology, Mayo Clinic, Rochester, Minnesota, USA. Division of Rheumatology, Brest Teaching Hospital, LBAI, UMR1227, Univ Brest, Inserm, CHU de Brest, Brest, France. G. Figueroa-Parra, MD, Division of Rheumatology, Mayo Clinic, Rochester, Minnesota, USA. J.X. Yang, MD, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA. C.A. Hulshizer, BA, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA. T.M. Gunderson, MS, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA. S.Q. Duong, MS, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA. M.S. Putman, MD, MSci, Division of Rheumatology, Department of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin, USA. K.E. Barbour, PhD, MPH, MS, Division of Population Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia, USA. C.S. Crowson, PhD, Division of Rheumatology, Mayo Clinic, Rochester, Minnesota, USA, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA. Alí Duarte- García, MD, MSc, Division of Rheumatology, Mayo Clinic, Rochester, Minnesota, USA, Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, Minnesota, USA. Corresponding author: Alí Duarte-García MD, MSc, Mayo Clinic, 200 First Street SW, Rochester, MN 55905. Email: duarte.ali@mayo.edu
Kamil E. Barbour
Funding Information: The Lupus Midwest Network (LUMEN) project is supported by the Centers for Disease Control and Prevention of the U.S. Department of Health and Human Services (HHS) under Grant number U01 DP006491 as part of a financial assistance award totaling $1,750,000 with 100 percent funded by CDC/HHS. The contents are those of the author(s) and do not necessarily represent the official views of, nor an endorsement, by CDC/HHS, or the U.S. Government. The Rochester Epidemiology Project was supported by the National Institute on Aging of the National Institutes of Health under Award Number R01AG034676, and Grant Number UL1 TR002377 from the National Center for Advancing Translational Sciences (NCATS), a component of the National Institutes of Health. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. CDC Disclaimer: The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the CDC. B. Chevet, MD, Division of Rheumatology, Mayo Clinic, Rochester, Minnesota, USA. Division of Rheumatology, Brest Teaching Hospital, LBAI, UMR1227, Univ Brest, Inserm, CHU de Brest, Brest, France. G. Figueroa-Parra, MD, Division of Rheumatology, Mayo Clinic, Rochester, Minnesota, USA. J.X. Yang, MD, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA. C.A. Hulshizer, BA, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA. T.M. Gunderson, MS, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA. S.Q. Duong, MS, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA. M.S. Putman, MD, MSci, Division of Rheumatology, Department of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin, USA. K.E. Barbour, PhD, MPH, MS, Division of Population Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia, USA. C.S. Crowson, PhD, Division of Rheumatology, Mayo Clinic, Rochester, Minnesota, USA, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA. Alí Duarte- García, MD, MSc, Division of Rheumatology, Mayo Clinic, Rochester, Minnesota, USA, Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, Minnesota, USA. Corresponding author: Alí Duarte-García MD, MSc, Mayo Clinic, 200 First Street SW, Rochester, MN 55905. Email: duarte.ali@mayo.edu
Cynthia S. Crowson
Funding Information: The Lupus Midwest Network (LUMEN) project is supported by the Centers for Disease Control and Prevention of the U.S. Department of Health and Human Services (HHS) under Grant number U01 DP006491 as part of a financial assistance award totaling $1,750,000 with 100 percent funded by CDC/HHS. The contents are those of the author(s) and do not necessarily represent the official views of, nor an endorsement, by CDC/HHS, or the U.S. Government. The Rochester Epidemiology Project was supported by the National Institute on Aging of the National Institutes of Health under Award Number R01AG034676, and Grant Number UL1 TR002377 from the National Center for Advancing Translational Sciences (NCATS), a component of the National Institutes of Health. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. CDC Disclaimer: The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the CDC. B. Chevet, MD, Division of Rheumatology, Mayo Clinic, Rochester, Minnesota, USA. Division of Rheumatology, Brest Teaching Hospital, LBAI, UMR1227, Univ Brest, Inserm, CHU de Brest, Brest, France. G. Figueroa-Parra, MD, Division of Rheumatology, Mayo Clinic, Rochester, Minnesota, USA. J.X. Yang, MD, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA. C.A. Hulshizer, BA, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA. T.M. Gunderson, MS, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA. S.Q. Duong, MS, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA. M.S. Putman, MD, MSci, Division of Rheumatology, Department of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin, USA. K.E. Barbour, PhD, MPH, MS, Division of Population Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia, USA. C.S. Crowson, PhD, Division of Rheumatology, Mayo Clinic, Rochester, Minnesota, USA, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA. Alí Duarte- García, MD, MSc, Division of Rheumatology, Mayo Clinic, Rochester, Minnesota, USA, Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, Minnesota, USA. Corresponding author: Alí Duarte-García MD, MSc, Mayo Clinic, 200 First Street SW, Rochester, MN 55905. Email: duarte.ali@mayo.edu
Alí Duarte-García
Funding Information: The Lupus Midwest Network (LUMEN) project is supported by the Centers for Disease Control and Prevention of the U.S. Department of Health and Human Services (HHS) under Grant number U01 DP006491 as part of a financial assistance award totaling $1,750,000 with 100 percent funded by CDC/HHS. The contents are those of the author(s) and do not necessarily represent the official views of, nor an endorsement, by CDC/HHS, or the U.S. Government. The Rochester Epidemiology Project was supported by the National Institute on Aging of the National Institutes of Health under Award Number R01AG034676, and Grant Number UL1 TR002377 from the National Center for Advancing Translational Sciences (NCATS), a component of the National Institutes of Health. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. CDC Disclaimer: The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the CDC. B. Chevet, MD, Division of Rheumatology, Mayo Clinic, Rochester, Minnesota, USA. Division of Rheumatology, Brest Teaching Hospital, LBAI, UMR1227, Univ Brest, Inserm, CHU de Brest, Brest, France. G. Figueroa-Parra, MD, Division of Rheumatology, Mayo Clinic, Rochester, Minnesota, USA. J.X. Yang, MD, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA. C.A. Hulshizer, BA, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA. T.M. Gunderson, MS, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA. S.Q. Duong, MS, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA. M.S. Putman, MD, MSci, Division of Rheumatology, Department of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin, USA. K.E. Barbour, PhD, MPH, MS, Division of Population Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia, USA. C.S. Crowson, PhD, Division of Rheumatology, Mayo Clinic, Rochester, Minnesota, USA, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA. Alí Duarte- García, MD, MSc, Division of Rheumatology, Mayo Clinic, Rochester, Minnesota, USA, Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, Minnesota, USA. Corresponding author: Alí Duarte-García MD, MSc, Mayo Clinic, 200 First Street SW, Rochester, MN 55905. Email: duarte.ali@mayo.edu
Abstract
Objective Systemic lupus erythematosus (SLE) patients are at higher risk of poor outcomes from coronavirus disease 2019 (COVID-19). The vaccination rate among such patients is unknown. We aimed to assess COVID-19 vaccine uptake among SLE patients.
Methods We included 342 SLE patients from the Lupus Midwest Network and 350 age, sex, race, and county matched comparators. Vaccination uptake for influenza, pneumococcal, and zoster vaccines before pandemic restrictions began (up to February 29, 2020) was assessed. First-dose COVID-19 vaccine uptake was electronically retrieved and manually ascertained (December 15, 2020, to July 31, 2021). Time to COVID-19 vaccination, demographics, lupus manifestations, medications, comorbidity index, area deprivation index, and rurality measures were compared.
Results On July 31, 2021, 83.3% of SLE patients and 85.5% of comparators were vaccinated against COVID-19. The COVID-19 vaccination rates were similar among SLE and comparators (hazard ratio: 0.93; 95% CI: 0.79–1.10). Non-vaccinated SLE patients were more likely to be men (27.3% versus 14.1% vaccinated), younger (mean 54.1 versus 58.8 years in vaccinated), have a shorter SLE duration (median 7.3 versus 10.7 years in vaccinated), and be less frequently vaccinated with influenza and pneumococcal vaccine.
Conclusion SLE patients in the Lupus Midwest Network had similar COVID-19 vaccination uptake as matched comparators, most of whom were vaccinated early when the vaccine became available. One in six remain unvaccinated.
In this issue
The Journal of Rheumatology
Vol. 49, Issue 8
1 Aug 2022
COVID-19 vaccine uptake among patients with systemic lupus erythematosus in the American Midwest: The Lupus Midwest Network (LUMEN)
Baptiste Chevet, Gabriel Figueroa-Parra, Jeffrey X. Yang, Cassondra A. Hulshizer, Tina M. Gunderson, Stephanie Q. Duong, Michael S. Putman, Kamil E. Barbour, Cynthia S. Crowson, Alí Duarte-García
The Journal of Rheumatology Jul 2022, jrheum.220220; DOI: 10.3899/jrheum.220220
COVID-19 vaccine uptake among patients with systemic lupus erythematosus in the American Midwest: The Lupus Midwest Network (LUMEN)
Baptiste Chevet, Gabriel Figueroa-Parra, Jeffrey X. Yang, Cassondra A. Hulshizer, Tina M. Gunderson, Stephanie Q. Duong, Michael S. Putman, Kamil E. Barbour, Cynthia S. Crowson, Alí Duarte-García
The Journal of Rheumatology Jul 2022, jrheum.220220; DOI: 10.3899/jrheum.220220
