LetterLetter
Could Sampling Bias Be to Blame for Apparent Association Among Rheumatic Diseases?
Pei-Yu Liao, Chun Hsien Wu, Yu-Chen Guo, Je-Kuei Yang and James Cheng-Chung Wei
The Journal of Rheumatology July 2022, jrheum.210961; DOI: https://doi.org/10.3899/jrheum.210961
Pei-Yu Liao
School of Medicine, Chung Shan Medical University; Department of Physical Medicine and Rehabilitation, Chung Shan Medical University Hospital; Institute of Medicine, Chung Shan Medical University; Graduate Institute of Integrated Medicine, China Medical University; Division of Allergy, Immunology and Rheumatology, Department of Internal Medicine, Chung Shan Medical University Hospital, Taichung, Taiwan. P.Y. Liao and J.K. Yang contributed equally. The authors declare no conflicts of interest relevant to this work. Address correspondence to Dr. J.C.C. Wei, Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan; Graduate Institute of Integrated Medicine, China Medical University; Division of Allergy, Immunology and Rheumatology, Department of Internal Medicine, Chung Shan Medical University Hospital, No. 110, Sec. 1, Jianguo N. Rd., Taichung City 40201, Taiwan. Email: jccwei@gmail.com.
Chun Hsien Wu
School of Medicine, Chung Shan Medical University; Department of Physical Medicine and Rehabilitation, Chung Shan Medical University Hospital; Institute of Medicine, Chung Shan Medical University; Graduate Institute of Integrated Medicine, China Medical University; Division of Allergy, Immunology and Rheumatology, Department of Internal Medicine, Chung Shan Medical University Hospital, Taichung, Taiwan. P.Y. Liao and J.K. Yang contributed equally. The authors declare no conflicts of interest relevant to this work. Address correspondence to Dr. J.C.C. Wei, Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan; Graduate Institute of Integrated Medicine, China Medical University; Division of Allergy, Immunology and Rheumatology, Department of Internal Medicine, Chung Shan Medical University Hospital, No. 110, Sec. 1, Jianguo N. Rd., Taichung City 40201, Taiwan. Email: jccwei@gmail.com.
Yu-Chen Guo
School of Medicine, Chung Shan Medical University; Department of Physical Medicine and Rehabilitation, Chung Shan Medical University Hospital; Institute of Medicine, Chung Shan Medical University; Graduate Institute of Integrated Medicine, China Medical University; Division of Allergy, Immunology and Rheumatology, Department of Internal Medicine, Chung Shan Medical University Hospital, Taichung, Taiwan. P.Y. Liao and J.K. Yang contributed equally. The authors declare no conflicts of interest relevant to this work. Address correspondence to Dr. J.C.C. Wei, Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan; Graduate Institute of Integrated Medicine, China Medical University; Division of Allergy, Immunology and Rheumatology, Department of Internal Medicine, Chung Shan Medical University Hospital, No. 110, Sec. 1, Jianguo N. Rd., Taichung City 40201, Taiwan. Email: jccwei@gmail.com.
Je-Kuei Yang
School of Medicine, Chung Shan Medical University; Department of Physical Medicine and Rehabilitation, Chung Shan Medical University Hospital; Institute of Medicine, Chung Shan Medical University; Graduate Institute of Integrated Medicine, China Medical University; Division of Allergy, Immunology and Rheumatology, Department of Internal Medicine, Chung Shan Medical University Hospital, Taichung, Taiwan. P.Y. Liao and J.K. Yang contributed equally. The authors declare no conflicts of interest relevant to this work. Address correspondence to Dr. J.C.C. Wei, Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan; Graduate Institute of Integrated Medicine, China Medical University; Division of Allergy, Immunology and Rheumatology, Department of Internal Medicine, Chung Shan Medical University Hospital, No. 110, Sec. 1, Jianguo N. Rd., Taichung City 40201, Taiwan. Email: jccwei@gmail.com.
James Cheng-Chung Wei
School of Medicine, Chung Shan Medical University; Department of Physical Medicine and Rehabilitation, Chung Shan Medical University Hospital; Institute of Medicine, Chung Shan Medical University; Graduate Institute of Integrated Medicine, China Medical University; Division of Allergy, Immunology and Rheumatology, Department of Internal Medicine, Chung Shan Medical University Hospital, Taichung, Taiwan. P.Y. Liao and J.K. Yang contributed equally. The authors declare no conflicts of interest relevant to this work. Address correspondence to Dr. J.C.C. Wei, Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan; Graduate Institute of Integrated Medicine, China Medical University; Division of Allergy, Immunology and Rheumatology, Department of Internal Medicine, Chung Shan Medical University Hospital, No. 110, Sec. 1, Jianguo N. Rd., Taichung City 40201, Taiwan. Email: jccwei@gmail.com.

Abstract
We have read with great interest the recent study by Meer et al on novel methods to identify risk factors for psoriatic arthritis (PsA), psoriasis, rheumatoid arthritis (RA), and ankylosing spondylitis.1 In that article, we appreciate that age, sex, BMI (calculated as weight in kilograms divided by height in meters squared), and time observed between the experimental group and control group were highly matched. However, we have a few suggestions to strengthen the conclusions in the study of Meer et al.
In this issue
The Journal of Rheumatology
Vol. 49, Issue 8
1 Aug 2022
Could Sampling Bias Be to Blame for Apparent Association Among Rheumatic Diseases?
Pei-Yu Liao, Chun Hsien Wu, Yu-Chen Guo, Je-Kuei Yang, James Cheng-Chung Wei
The Journal of Rheumatology Jul 2022, jrheum.210961; DOI: 10.3899/jrheum.210961