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LetterLetter

Some Key Issues Relating to the Reporting and Interpretation of Time-to-event Data

I. Manjula Schou
The Journal of Rheumatology May 2022, jrheum.220053; DOI: https://doi.org/10.3899/jrheum.220053
I. Manjula Schou
NHMRC Clinical Trials Centre, University of Sydney, Sydney, Australia. IMS holds Pfizer stock options. Address correspondence to Dr. I.M. Schou, NHMRC Clinical Trials Centre, University of Sydney, 92-94 Parramatta Road, Sydney, NSW 2050, Australia. Email: manjula.schou@sydney.edu.au.
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Abstract

Griffiths et al recently reported that in a cohort of Australian patients with ankylosing spondylitis included in the Optimising Patient outcomes in Australian RheumatoLogy (OPAL) dataset, the median persistence (persistence defined as the time to discontinuation of treatment) was longest for patients treated with golimumab (GOL) in all lines of therapy, and shortest for those treated with etanercept (ETN).1 In drawing this conclusion, the authors have overlooked some statistical aspects relating to the reporting of time-to-event data that make it difficult to evaluate the robustness of their conclusions.

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The Journal of Rheumatology
Vol. 49, Issue 7
1 Jul 2022
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Some Key Issues Relating to the Reporting and Interpretation of Time-to-event Data
I. Manjula Schou
The Journal of Rheumatology May 2022, jrheum.220053; DOI: 10.3899/jrheum.220053

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Some Key Issues Relating to the Reporting and Interpretation of Time-to-event Data
I. Manjula Schou
The Journal of Rheumatology May 2022, jrheum.220053; DOI: 10.3899/jrheum.220053
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