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LetterResearch Letter

Impaired Humoral Immunogenicity of SARS-CoV-2 Vaccination in Patients With Rheumatoid Arthritis

Camille Le Moine, Muhammad Shahnawaz Soyfoo, Leila Mekkaoui, Hafid Dahma and Laure Tant
The Journal of Rheumatology February 2022, jrheum.211270; DOI: https://doi.org/10.3899/jrheum.211270
Camille Le Moine
Department of Rheumatology, Hôpital Erasme, Université Libre de Bruxelles; Microbiology Department, Laboratoire Hospitalier Universitaire de Bruxelles – Universitair Laboratorium Brussel (LHUB-ULB), Université Libre de Bruxelles, Brussels, Belgium. This work was supported by the Rheumatology Department of Hôpital Erasme, Brussels, Belgium. The authors declare no conflicts of interest relevant to this article. Address correspondence to Dr. C. Le Moine, Department of Rheumatology, Hôpital Erasme, Université Libre de Bruxelles, 808 Route de Lennik, B-1070 Brussels, Belgium. Email: camille.le.moine@erasme.ulb.ac.be.
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Muhammad Shahnawaz Soyfoo
Department of Rheumatology, Hôpital Erasme, Université Libre de Bruxelles; Microbiology Department, Laboratoire Hospitalier Universitaire de Bruxelles – Universitair Laboratorium Brussel (LHUB-ULB), Université Libre de Bruxelles, Brussels, Belgium. This work was supported by the Rheumatology Department of Hôpital Erasme, Brussels, Belgium. The authors declare no conflicts of interest relevant to this article. Address correspondence to Dr. C. Le Moine, Department of Rheumatology, Hôpital Erasme, Université Libre de Bruxelles, 808 Route de Lennik, B-1070 Brussels, Belgium. Email: camille.le.moine@erasme.ulb.ac.be.
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Leila Mekkaoui
Department of Rheumatology, Hôpital Erasme, Université Libre de Bruxelles; Microbiology Department, Laboratoire Hospitalier Universitaire de Bruxelles – Universitair Laboratorium Brussel (LHUB-ULB), Université Libre de Bruxelles, Brussels, Belgium. This work was supported by the Rheumatology Department of Hôpital Erasme, Brussels, Belgium. The authors declare no conflicts of interest relevant to this article. Address correspondence to Dr. C. Le Moine, Department of Rheumatology, Hôpital Erasme, Université Libre de Bruxelles, 808 Route de Lennik, B-1070 Brussels, Belgium. Email: camille.le.moine@erasme.ulb.ac.be.
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Hafid Dahma
Department of Rheumatology, Hôpital Erasme, Université Libre de Bruxelles; Microbiology Department, Laboratoire Hospitalier Universitaire de Bruxelles – Universitair Laboratorium Brussel (LHUB-ULB), Université Libre de Bruxelles, Brussels, Belgium. This work was supported by the Rheumatology Department of Hôpital Erasme, Brussels, Belgium. The authors declare no conflicts of interest relevant to this article. Address correspondence to Dr. C. Le Moine, Department of Rheumatology, Hôpital Erasme, Université Libre de Bruxelles, 808 Route de Lennik, B-1070 Brussels, Belgium. Email: camille.le.moine@erasme.ulb.ac.be.
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Laure Tant
Department of Rheumatology, Hôpital Erasme, Université Libre de Bruxelles; Microbiology Department, Laboratoire Hospitalier Universitaire de Bruxelles – Universitair Laboratorium Brussel (LHUB-ULB), Université Libre de Bruxelles, Brussels, Belgium. This work was supported by the Rheumatology Department of Hôpital Erasme, Brussels, Belgium. The authors declare no conflicts of interest relevant to this article. Address correspondence to Dr. C. Le Moine, Department of Rheumatology, Hôpital Erasme, Université Libre de Bruxelles, 808 Route de Lennik, B-1070 Brussels, Belgium. Email: camille.le.moine@erasme.ulb.ac.be.
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Abstract

Humoral immunogenicity of SARS-CoV-2 vaccination in rheumatoid arthritis (RA) seems impaired depending on the underlying immunosuppressive agents, especially with rituximab (RTX), glucocorticoids, and abatacept (ABA), but data are still scarce.1–9 Identifying an impairment could lead to treatment adaptation or a vaccine booster dose to improve vaccine response.

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The Journal of Rheumatology
Vol. 49, Issue 6
1 Jun 2022
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Impaired Humoral Immunogenicity of SARS-CoV-2 Vaccination in Patients With Rheumatoid Arthritis
Camille Le Moine, Muhammad Shahnawaz Soyfoo, Leila Mekkaoui, Hafid Dahma, Laure Tant
The Journal of Rheumatology Feb 2022, jrheum.211270; DOI: 10.3899/jrheum.211270

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Impaired Humoral Immunogenicity of SARS-CoV-2 Vaccination in Patients With Rheumatoid Arthritis
Camille Le Moine, Muhammad Shahnawaz Soyfoo, Leila Mekkaoui, Hafid Dahma, Laure Tant
The Journal of Rheumatology Feb 2022, jrheum.211270; DOI: 10.3899/jrheum.211270
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