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Research ArticleArticle

Schizophrenia Genetics and Neuropsychiatric Features in Childhood-onset Systemic Lupus Erythematosus

Ana C. Ulloa, Fangming Liao, Raffaella L. Carlomagno, Talia Diaz, Daniela Dominguez, Deborah M. Levy, Lawrence Ng, Andrea M. Knight and Linda T. Hiraki
The Journal of Rheumatology October 2021, jrheum.210363; DOI: https://doi.org/10.3899/jrheum.210363
Ana C. Ulloa
LTH is supported by The Arthritis Society Stars Career Award. A.C. Ulloa, MPH, Genetics & Genome Biology, Research Institute, The Hospital for Sick Children; F. Liao, MSc, R.L. Carlomagno, MD, T. Diaz, MD, D. Dominguez, MD, MSc, L. Ng, BSc, A.M. Knight, MD, MSCE, Division of Rheumatology, The Hospital for Sick Children; D.M. Levy, MD, MS, Division of Rheumatology, The Hospital for Sick Children, and Department of Pediatrics, The University of Toronto; L.T. Hiraki, MD, FRCPC, ScD, Genetics & Genome Biology, Research Institute, and Division of Rheumatology, The Hospital for Sick Children, and Department of Pediatrics, The University of Toronto, Toronto, Ontario, Canada. The authors declare no conflicts of interest relevant to this article. Address correspondence to Dr. L.T. Hiraki, Peter Gilgan Centre for Research and Learning, 686 Bay St., Toronto, ON M5G 0A4, Canada. Email: linda.hiraki@sickkids.ca. Accepted for publication September 23, 2021.
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Fangming Liao
LTH is supported by The Arthritis Society Stars Career Award. A.C. Ulloa, MPH, Genetics & Genome Biology, Research Institute, The Hospital for Sick Children; F. Liao, MSc, R.L. Carlomagno, MD, T. Diaz, MD, D. Dominguez, MD, MSc, L. Ng, BSc, A.M. Knight, MD, MSCE, Division of Rheumatology, The Hospital for Sick Children; D.M. Levy, MD, MS, Division of Rheumatology, The Hospital for Sick Children, and Department of Pediatrics, The University of Toronto; L.T. Hiraki, MD, FRCPC, ScD, Genetics & Genome Biology, Research Institute, and Division of Rheumatology, The Hospital for Sick Children, and Department of Pediatrics, The University of Toronto, Toronto, Ontario, Canada. The authors declare no conflicts of interest relevant to this article. Address correspondence to Dr. L.T. Hiraki, Peter Gilgan Centre for Research and Learning, 686 Bay St., Toronto, ON M5G 0A4, Canada. Email: linda.hiraki@sickkids.ca. Accepted for publication September 23, 2021.
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Raffaella L. Carlomagno
LTH is supported by The Arthritis Society Stars Career Award. A.C. Ulloa, MPH, Genetics & Genome Biology, Research Institute, The Hospital for Sick Children; F. Liao, MSc, R.L. Carlomagno, MD, T. Diaz, MD, D. Dominguez, MD, MSc, L. Ng, BSc, A.M. Knight, MD, MSCE, Division of Rheumatology, The Hospital for Sick Children; D.M. Levy, MD, MS, Division of Rheumatology, The Hospital for Sick Children, and Department of Pediatrics, The University of Toronto; L.T. Hiraki, MD, FRCPC, ScD, Genetics & Genome Biology, Research Institute, and Division of Rheumatology, The Hospital for Sick Children, and Department of Pediatrics, The University of Toronto, Toronto, Ontario, Canada. The authors declare no conflicts of interest relevant to this article. Address correspondence to Dr. L.T. Hiraki, Peter Gilgan Centre for Research and Learning, 686 Bay St., Toronto, ON M5G 0A4, Canada. Email: linda.hiraki@sickkids.ca. Accepted for publication September 23, 2021.
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Talia Diaz
LTH is supported by The Arthritis Society Stars Career Award. A.C. Ulloa, MPH, Genetics & Genome Biology, Research Institute, The Hospital for Sick Children; F. Liao, MSc, R.L. Carlomagno, MD, T. Diaz, MD, D. Dominguez, MD, MSc, L. Ng, BSc, A.M. Knight, MD, MSCE, Division of Rheumatology, The Hospital for Sick Children; D.M. Levy, MD, MS, Division of Rheumatology, The Hospital for Sick Children, and Department of Pediatrics, The University of Toronto; L.T. Hiraki, MD, FRCPC, ScD, Genetics & Genome Biology, Research Institute, and Division of Rheumatology, The Hospital for Sick Children, and Department of Pediatrics, The University of Toronto, Toronto, Ontario, Canada. The authors declare no conflicts of interest relevant to this article. Address correspondence to Dr. L.T. Hiraki, Peter Gilgan Centre for Research and Learning, 686 Bay St., Toronto, ON M5G 0A4, Canada. Email: linda.hiraki@sickkids.ca. Accepted for publication September 23, 2021.
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Daniela Dominguez
LTH is supported by The Arthritis Society Stars Career Award. A.C. Ulloa, MPH, Genetics & Genome Biology, Research Institute, The Hospital for Sick Children; F. Liao, MSc, R.L. Carlomagno, MD, T. Diaz, MD, D. Dominguez, MD, MSc, L. Ng, BSc, A.M. Knight, MD, MSCE, Division of Rheumatology, The Hospital for Sick Children; D.M. Levy, MD, MS, Division of Rheumatology, The Hospital for Sick Children, and Department of Pediatrics, The University of Toronto; L.T. Hiraki, MD, FRCPC, ScD, Genetics & Genome Biology, Research Institute, and Division of Rheumatology, The Hospital for Sick Children, and Department of Pediatrics, The University of Toronto, Toronto, Ontario, Canada. The authors declare no conflicts of interest relevant to this article. Address correspondence to Dr. L.T. Hiraki, Peter Gilgan Centre for Research and Learning, 686 Bay St., Toronto, ON M5G 0A4, Canada. Email: linda.hiraki@sickkids.ca. Accepted for publication September 23, 2021.
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Deborah M. Levy
LTH is supported by The Arthritis Society Stars Career Award. A.C. Ulloa, MPH, Genetics & Genome Biology, Research Institute, The Hospital for Sick Children; F. Liao, MSc, R.L. Carlomagno, MD, T. Diaz, MD, D. Dominguez, MD, MSc, L. Ng, BSc, A.M. Knight, MD, MSCE, Division of Rheumatology, The Hospital for Sick Children; D.M. Levy, MD, MS, Division of Rheumatology, The Hospital for Sick Children, and Department of Pediatrics, The University of Toronto; L.T. Hiraki, MD, FRCPC, ScD, Genetics & Genome Biology, Research Institute, and Division of Rheumatology, The Hospital for Sick Children, and Department of Pediatrics, The University of Toronto, Toronto, Ontario, Canada. The authors declare no conflicts of interest relevant to this article. Address correspondence to Dr. L.T. Hiraki, Peter Gilgan Centre for Research and Learning, 686 Bay St., Toronto, ON M5G 0A4, Canada. Email: linda.hiraki@sickkids.ca. Accepted for publication September 23, 2021.
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Lawrence Ng
LTH is supported by The Arthritis Society Stars Career Award. A.C. Ulloa, MPH, Genetics & Genome Biology, Research Institute, The Hospital for Sick Children; F. Liao, MSc, R.L. Carlomagno, MD, T. Diaz, MD, D. Dominguez, MD, MSc, L. Ng, BSc, A.M. Knight, MD, MSCE, Division of Rheumatology, The Hospital for Sick Children; D.M. Levy, MD, MS, Division of Rheumatology, The Hospital for Sick Children, and Department of Pediatrics, The University of Toronto; L.T. Hiraki, MD, FRCPC, ScD, Genetics & Genome Biology, Research Institute, and Division of Rheumatology, The Hospital for Sick Children, and Department of Pediatrics, The University of Toronto, Toronto, Ontario, Canada. The authors declare no conflicts of interest relevant to this article. Address correspondence to Dr. L.T. Hiraki, Peter Gilgan Centre for Research and Learning, 686 Bay St., Toronto, ON M5G 0A4, Canada. Email: linda.hiraki@sickkids.ca. Accepted for publication September 23, 2021.
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Andrea M. Knight
LTH is supported by The Arthritis Society Stars Career Award. A.C. Ulloa, MPH, Genetics & Genome Biology, Research Institute, The Hospital for Sick Children; F. Liao, MSc, R.L. Carlomagno, MD, T. Diaz, MD, D. Dominguez, MD, MSc, L. Ng, BSc, A.M. Knight, MD, MSCE, Division of Rheumatology, The Hospital for Sick Children; D.M. Levy, MD, MS, Division of Rheumatology, The Hospital for Sick Children, and Department of Pediatrics, The University of Toronto; L.T. Hiraki, MD, FRCPC, ScD, Genetics & Genome Biology, Research Institute, and Division of Rheumatology, The Hospital for Sick Children, and Department of Pediatrics, The University of Toronto, Toronto, Ontario, Canada. The authors declare no conflicts of interest relevant to this article. Address correspondence to Dr. L.T. Hiraki, Peter Gilgan Centre for Research and Learning, 686 Bay St., Toronto, ON M5G 0A4, Canada. Email: linda.hiraki@sickkids.ca. Accepted for publication September 23, 2021.
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Linda T. Hiraki
LTH is supported by The Arthritis Society Stars Career Award. A.C. Ulloa, MPH, Genetics & Genome Biology, Research Institute, The Hospital for Sick Children; F. Liao, MSc, R.L. Carlomagno, MD, T. Diaz, MD, D. Dominguez, MD, MSc, L. Ng, BSc, A.M. Knight, MD, MSCE, Division of Rheumatology, The Hospital for Sick Children; D.M. Levy, MD, MS, Division of Rheumatology, The Hospital for Sick Children, and Department of Pediatrics, The University of Toronto; L.T. Hiraki, MD, FRCPC, ScD, Genetics & Genome Biology, Research Institute, and Division of Rheumatology, The Hospital for Sick Children, and Department of Pediatrics, The University of Toronto, Toronto, Ontario, Canada. The authors declare no conflicts of interest relevant to this article. Address correspondence to Dr. L.T. Hiraki, Peter Gilgan Centre for Research and Learning, 686 Bay St., Toronto, ON M5G 0A4, Canada. Email: linda.hiraki@sickkids.ca. Accepted for publication September 23, 2021.
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Article Information

jrheum.210363
DOI 
https://doi.org/10.3899/jrheum.210363
PubMed 
34599046

Published By 
The Journal of Rheumatology
Print ISSN 
0315-162X
Online ISSN 
1499-2752
History 
  • Published online December 15, 2021.

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  • Latest version (October 1, 2021 - 04:00).
  • You are currently viewing a Latest version of this article (December 15, 2021 - 04:00).
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Copyright & Usage 
© 2021 The Journal of Rheumatology

Author Information

  1. Ana C. Ulloa,
  2. Fangming Liao,
  3. Raffaella L. Carlomagno,
  4. Talia Diaz,
  5. Daniela Dominguez,
  6. Deborah M. Levy,
  7. Lawrence Ng,
  8. Andrea M. Knight and
  9. Linda T. Hiraki
  1. LTH is supported by The Arthritis Society Stars Career Award.
    A.C. Ulloa, MPH, Genetics & Genome Biology, Research Institute, The Hospital for Sick Children; F. Liao, MSc, R.L. Carlomagno, MD, T. Diaz, MD, D. Dominguez, MD, MSc, L. Ng, BSc, A.M. Knight, MD, MSCE, Division of Rheumatology, The Hospital for Sick Children; D.M. Levy, MD, MS, Division of Rheumatology, The Hospital for Sick Children, and Department of Pediatrics, The University of Toronto; L.T. Hiraki, MD, FRCPC, ScD, Genetics & Genome Biology, Research Institute, and Division of Rheumatology, The Hospital for Sick Children, and Department of Pediatrics, The University of Toronto, Toronto, Ontario, Canada.
    The authors declare no conflicts of interest relevant to this article.
    Address correspondence to Dr. L.T. Hiraki, Peter Gilgan Centre for Research and Learning, 686 Bay St., Toronto, ON M5G 0A4, Canada. Email: linda.hiraki@sickkids.ca.
    Accepted for publication September 23, 2021.

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The Journal of Rheumatology: 52 (7)
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Schizophrenia Genetics and Neuropsychiatric Features in Childhood-onset Systemic Lupus Erythematosus
Ana C. Ulloa, Fangming Liao, Raffaella L. Carlomagno, Talia Diaz, Daniela Dominguez, Deborah M. Levy, Lawrence Ng, Andrea M. Knight, Linda T. Hiraki
The Journal of Rheumatology Oct 2021, jrheum.210363; DOI: 10.3899/jrheum.210363

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Schizophrenia Genetics and Neuropsychiatric Features in Childhood-onset Systemic Lupus Erythematosus
Ana C. Ulloa, Fangming Liao, Raffaella L. Carlomagno, Talia Diaz, Daniela Dominguez, Deborah M. Levy, Lawrence Ng, Andrea M. Knight, Linda T. Hiraki
The Journal of Rheumatology Oct 2021, jrheum.210363; DOI: 10.3899/jrheum.210363
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