Research ArticleArticle
Relationship of Patellofemoral Osteoarthritis to Changes in Performance-based Physical Function Over 7 Years: The Multicenter Osteoarthritis Study
Harvi F. Hart, Tuhina Neogi, Michael LaValley, Daniel White, Yuqing Zhang, Michael C. Nevitt, James Torner, Cora E. Lewis and Joshua J. Stefanik
The Journal of Rheumatology September 2021, jrheum.210270; DOI: https://doi.org/10.3899/jrheum.210270
Harvi F. Hart
The Multicenter Osteoarthritis Study was funded by the National Institutes of Health (NIH)/ National Institute on Aging UO1 AG18820, UO1 AG18832, UO1 AG18947, and UO1 AG19069. HFH is funded by a Canadian Institutes of Health Research Fellowship. JJS is supported by NIH/ NIAMS K23 AR070913. TN was supported by NIH/ National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) K24AR070892. This work was also supported by NIH/NIAMS P30AR072571. Funding sources had no role in the study design, collection, analysis, and interpretation of the data or the decision to submit the manuscript for publication. H.F. Hart, PhD, Faculty of Health Sciences and Bone and Joint Institute, Western University, London, Ontario, Canada; T. Neogi, MD, PhD, Division of Rheumatology, Boston University School of Medicine, Boston, Massachusetts, USA; M. LaValley, PhD, Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA; D. White, PT, PhD, Department of Physical Therapy, University of Delaware, Newark, Delaware, USA; Y. Zhang, DSc, Department of Rheumatology, Massachusetts General Hospital, Boston, Massachusetts, USA; M.C. Nevitt, PhD, MPH, Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California, USA; J. Torner, PhD, Department of Epidemiology, The University of Iowa, Iowa City, Iowa, USA; C.E. Lewis, MD, MSPH, Department of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama, USA; J.J. Stefanik, PT, PhD, Division of Rheumatology, Boston University School of Medicine, and Department of Physical Therapy, Movement, and Rehabilitation Sciences, Northeastern University, Boston, Massachusetts, USA. The authors declare no conflicts of interest relevant to this article. Address correspondence to Dr. J.J. Stefanik, Department of Physical Therapy, Movement, and Rehabilitation Sciences, Northeastern University, Boston, MA 02115, USA. Email: j.stefanik@northeastern.edu. Accepted for publication August 18, 2021.
Tuhina Neogi
The Multicenter Osteoarthritis Study was funded by the National Institutes of Health (NIH)/ National Institute on Aging UO1 AG18820, UO1 AG18832, UO1 AG18947, and UO1 AG19069. HFH is funded by a Canadian Institutes of Health Research Fellowship. JJS is supported by NIH/ NIAMS K23 AR070913. TN was supported by NIH/ National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) K24AR070892. This work was also supported by NIH/NIAMS P30AR072571. Funding sources had no role in the study design, collection, analysis, and interpretation of the data or the decision to submit the manuscript for publication. H.F. Hart, PhD, Faculty of Health Sciences and Bone and Joint Institute, Western University, London, Ontario, Canada; T. Neogi, MD, PhD, Division of Rheumatology, Boston University School of Medicine, Boston, Massachusetts, USA; M. LaValley, PhD, Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA; D. White, PT, PhD, Department of Physical Therapy, University of Delaware, Newark, Delaware, USA; Y. Zhang, DSc, Department of Rheumatology, Massachusetts General Hospital, Boston, Massachusetts, USA; M.C. Nevitt, PhD, MPH, Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California, USA; J. Torner, PhD, Department of Epidemiology, The University of Iowa, Iowa City, Iowa, USA; C.E. Lewis, MD, MSPH, Department of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama, USA; J.J. Stefanik, PT, PhD, Division of Rheumatology, Boston University School of Medicine, and Department of Physical Therapy, Movement, and Rehabilitation Sciences, Northeastern University, Boston, Massachusetts, USA. The authors declare no conflicts of interest relevant to this article. Address correspondence to Dr. J.J. Stefanik, Department of Physical Therapy, Movement, and Rehabilitation Sciences, Northeastern University, Boston, MA 02115, USA. Email: j.stefanik@northeastern.edu. Accepted for publication August 18, 2021.
Michael LaValley
The Multicenter Osteoarthritis Study was funded by the National Institutes of Health (NIH)/ National Institute on Aging UO1 AG18820, UO1 AG18832, UO1 AG18947, and UO1 AG19069. HFH is funded by a Canadian Institutes of Health Research Fellowship. JJS is supported by NIH/ NIAMS K23 AR070913. TN was supported by NIH/ National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) K24AR070892. This work was also supported by NIH/NIAMS P30AR072571. Funding sources had no role in the study design, collection, analysis, and interpretation of the data or the decision to submit the manuscript for publication. H.F. Hart, PhD, Faculty of Health Sciences and Bone and Joint Institute, Western University, London, Ontario, Canada; T. Neogi, MD, PhD, Division of Rheumatology, Boston University School of Medicine, Boston, Massachusetts, USA; M. LaValley, PhD, Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA; D. White, PT, PhD, Department of Physical Therapy, University of Delaware, Newark, Delaware, USA; Y. Zhang, DSc, Department of Rheumatology, Massachusetts General Hospital, Boston, Massachusetts, USA; M.C. Nevitt, PhD, MPH, Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California, USA; J. Torner, PhD, Department of Epidemiology, The University of Iowa, Iowa City, Iowa, USA; C.E. Lewis, MD, MSPH, Department of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama, USA; J.J. Stefanik, PT, PhD, Division of Rheumatology, Boston University School of Medicine, and Department of Physical Therapy, Movement, and Rehabilitation Sciences, Northeastern University, Boston, Massachusetts, USA. The authors declare no conflicts of interest relevant to this article. Address correspondence to Dr. J.J. Stefanik, Department of Physical Therapy, Movement, and Rehabilitation Sciences, Northeastern University, Boston, MA 02115, USA. Email: j.stefanik@northeastern.edu. Accepted for publication August 18, 2021.
Daniel White
The Multicenter Osteoarthritis Study was funded by the National Institutes of Health (NIH)/ National Institute on Aging UO1 AG18820, UO1 AG18832, UO1 AG18947, and UO1 AG19069. HFH is funded by a Canadian Institutes of Health Research Fellowship. JJS is supported by NIH/ NIAMS K23 AR070913. TN was supported by NIH/ National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) K24AR070892. This work was also supported by NIH/NIAMS P30AR072571. Funding sources had no role in the study design, collection, analysis, and interpretation of the data or the decision to submit the manuscript for publication. H.F. Hart, PhD, Faculty of Health Sciences and Bone and Joint Institute, Western University, London, Ontario, Canada; T. Neogi, MD, PhD, Division of Rheumatology, Boston University School of Medicine, Boston, Massachusetts, USA; M. LaValley, PhD, Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA; D. White, PT, PhD, Department of Physical Therapy, University of Delaware, Newark, Delaware, USA; Y. Zhang, DSc, Department of Rheumatology, Massachusetts General Hospital, Boston, Massachusetts, USA; M.C. Nevitt, PhD, MPH, Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California, USA; J. Torner, PhD, Department of Epidemiology, The University of Iowa, Iowa City, Iowa, USA; C.E. Lewis, MD, MSPH, Department of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama, USA; J.J. Stefanik, PT, PhD, Division of Rheumatology, Boston University School of Medicine, and Department of Physical Therapy, Movement, and Rehabilitation Sciences, Northeastern University, Boston, Massachusetts, USA. The authors declare no conflicts of interest relevant to this article. Address correspondence to Dr. J.J. Stefanik, Department of Physical Therapy, Movement, and Rehabilitation Sciences, Northeastern University, Boston, MA 02115, USA. Email: j.stefanik@northeastern.edu. Accepted for publication August 18, 2021.
Yuqing Zhang
The Multicenter Osteoarthritis Study was funded by the National Institutes of Health (NIH)/ National Institute on Aging UO1 AG18820, UO1 AG18832, UO1 AG18947, and UO1 AG19069. HFH is funded by a Canadian Institutes of Health Research Fellowship. JJS is supported by NIH/ NIAMS K23 AR070913. TN was supported by NIH/ National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) K24AR070892. This work was also supported by NIH/NIAMS P30AR072571. Funding sources had no role in the study design, collection, analysis, and interpretation of the data or the decision to submit the manuscript for publication. H.F. Hart, PhD, Faculty of Health Sciences and Bone and Joint Institute, Western University, London, Ontario, Canada; T. Neogi, MD, PhD, Division of Rheumatology, Boston University School of Medicine, Boston, Massachusetts, USA; M. LaValley, PhD, Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA; D. White, PT, PhD, Department of Physical Therapy, University of Delaware, Newark, Delaware, USA; Y. Zhang, DSc, Department of Rheumatology, Massachusetts General Hospital, Boston, Massachusetts, USA; M.C. Nevitt, PhD, MPH, Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California, USA; J. Torner, PhD, Department of Epidemiology, The University of Iowa, Iowa City, Iowa, USA; C.E. Lewis, MD, MSPH, Department of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama, USA; J.J. Stefanik, PT, PhD, Division of Rheumatology, Boston University School of Medicine, and Department of Physical Therapy, Movement, and Rehabilitation Sciences, Northeastern University, Boston, Massachusetts, USA. The authors declare no conflicts of interest relevant to this article. Address correspondence to Dr. J.J. Stefanik, Department of Physical Therapy, Movement, and Rehabilitation Sciences, Northeastern University, Boston, MA 02115, USA. Email: j.stefanik@northeastern.edu. Accepted for publication August 18, 2021.
Michael C. Nevitt
The Multicenter Osteoarthritis Study was funded by the National Institutes of Health (NIH)/ National Institute on Aging UO1 AG18820, UO1 AG18832, UO1 AG18947, and UO1 AG19069. HFH is funded by a Canadian Institutes of Health Research Fellowship. JJS is supported by NIH/ NIAMS K23 AR070913. TN was supported by NIH/ National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) K24AR070892. This work was also supported by NIH/NIAMS P30AR072571. Funding sources had no role in the study design, collection, analysis, and interpretation of the data or the decision to submit the manuscript for publication. H.F. Hart, PhD, Faculty of Health Sciences and Bone and Joint Institute, Western University, London, Ontario, Canada; T. Neogi, MD, PhD, Division of Rheumatology, Boston University School of Medicine, Boston, Massachusetts, USA; M. LaValley, PhD, Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA; D. White, PT, PhD, Department of Physical Therapy, University of Delaware, Newark, Delaware, USA; Y. Zhang, DSc, Department of Rheumatology, Massachusetts General Hospital, Boston, Massachusetts, USA; M.C. Nevitt, PhD, MPH, Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California, USA; J. Torner, PhD, Department of Epidemiology, The University of Iowa, Iowa City, Iowa, USA; C.E. Lewis, MD, MSPH, Department of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama, USA; J.J. Stefanik, PT, PhD, Division of Rheumatology, Boston University School of Medicine, and Department of Physical Therapy, Movement, and Rehabilitation Sciences, Northeastern University, Boston, Massachusetts, USA. The authors declare no conflicts of interest relevant to this article. Address correspondence to Dr. J.J. Stefanik, Department of Physical Therapy, Movement, and Rehabilitation Sciences, Northeastern University, Boston, MA 02115, USA. Email: j.stefanik@northeastern.edu. Accepted for publication August 18, 2021.
James Torner
The Multicenter Osteoarthritis Study was funded by the National Institutes of Health (NIH)/ National Institute on Aging UO1 AG18820, UO1 AG18832, UO1 AG18947, and UO1 AG19069. HFH is funded by a Canadian Institutes of Health Research Fellowship. JJS is supported by NIH/ NIAMS K23 AR070913. TN was supported by NIH/ National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) K24AR070892. This work was also supported by NIH/NIAMS P30AR072571. Funding sources had no role in the study design, collection, analysis, and interpretation of the data or the decision to submit the manuscript for publication. H.F. Hart, PhD, Faculty of Health Sciences and Bone and Joint Institute, Western University, London, Ontario, Canada; T. Neogi, MD, PhD, Division of Rheumatology, Boston University School of Medicine, Boston, Massachusetts, USA; M. LaValley, PhD, Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA; D. White, PT, PhD, Department of Physical Therapy, University of Delaware, Newark, Delaware, USA; Y. Zhang, DSc, Department of Rheumatology, Massachusetts General Hospital, Boston, Massachusetts, USA; M.C. Nevitt, PhD, MPH, Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California, USA; J. Torner, PhD, Department of Epidemiology, The University of Iowa, Iowa City, Iowa, USA; C.E. Lewis, MD, MSPH, Department of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama, USA; J.J. Stefanik, PT, PhD, Division of Rheumatology, Boston University School of Medicine, and Department of Physical Therapy, Movement, and Rehabilitation Sciences, Northeastern University, Boston, Massachusetts, USA. The authors declare no conflicts of interest relevant to this article. Address correspondence to Dr. J.J. Stefanik, Department of Physical Therapy, Movement, and Rehabilitation Sciences, Northeastern University, Boston, MA 02115, USA. Email: j.stefanik@northeastern.edu. Accepted for publication August 18, 2021.
Cora E. Lewis
The Multicenter Osteoarthritis Study was funded by the National Institutes of Health (NIH)/ National Institute on Aging UO1 AG18820, UO1 AG18832, UO1 AG18947, and UO1 AG19069. HFH is funded by a Canadian Institutes of Health Research Fellowship. JJS is supported by NIH/ NIAMS K23 AR070913. TN was supported by NIH/ National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) K24AR070892. This work was also supported by NIH/NIAMS P30AR072571. Funding sources had no role in the study design, collection, analysis, and interpretation of the data or the decision to submit the manuscript for publication. H.F. Hart, PhD, Faculty of Health Sciences and Bone and Joint Institute, Western University, London, Ontario, Canada; T. Neogi, MD, PhD, Division of Rheumatology, Boston University School of Medicine, Boston, Massachusetts, USA; M. LaValley, PhD, Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA; D. White, PT, PhD, Department of Physical Therapy, University of Delaware, Newark, Delaware, USA; Y. Zhang, DSc, Department of Rheumatology, Massachusetts General Hospital, Boston, Massachusetts, USA; M.C. Nevitt, PhD, MPH, Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California, USA; J. Torner, PhD, Department of Epidemiology, The University of Iowa, Iowa City, Iowa, USA; C.E. Lewis, MD, MSPH, Department of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama, USA; J.J. Stefanik, PT, PhD, Division of Rheumatology, Boston University School of Medicine, and Department of Physical Therapy, Movement, and Rehabilitation Sciences, Northeastern University, Boston, Massachusetts, USA. The authors declare no conflicts of interest relevant to this article. Address correspondence to Dr. J.J. Stefanik, Department of Physical Therapy, Movement, and Rehabilitation Sciences, Northeastern University, Boston, MA 02115, USA. Email: j.stefanik@northeastern.edu. Accepted for publication August 18, 2021.
Joshua J. Stefanik
The Multicenter Osteoarthritis Study was funded by the National Institutes of Health (NIH)/ National Institute on Aging UO1 AG18820, UO1 AG18832, UO1 AG18947, and UO1 AG19069. HFH is funded by a Canadian Institutes of Health Research Fellowship. JJS is supported by NIH/ NIAMS K23 AR070913. TN was supported by NIH/ National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) K24AR070892. This work was also supported by NIH/NIAMS P30AR072571. Funding sources had no role in the study design, collection, analysis, and interpretation of the data or the decision to submit the manuscript for publication. H.F. Hart, PhD, Faculty of Health Sciences and Bone and Joint Institute, Western University, London, Ontario, Canada; T. Neogi, MD, PhD, Division of Rheumatology, Boston University School of Medicine, Boston, Massachusetts, USA; M. LaValley, PhD, Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA; D. White, PT, PhD, Department of Physical Therapy, University of Delaware, Newark, Delaware, USA; Y. Zhang, DSc, Department of Rheumatology, Massachusetts General Hospital, Boston, Massachusetts, USA; M.C. Nevitt, PhD, MPH, Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California, USA; J. Torner, PhD, Department of Epidemiology, The University of Iowa, Iowa City, Iowa, USA; C.E. Lewis, MD, MSPH, Department of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama, USA; J.J. Stefanik, PT, PhD, Division of Rheumatology, Boston University School of Medicine, and Department of Physical Therapy, Movement, and Rehabilitation Sciences, Northeastern University, Boston, Massachusetts, USA. The authors declare no conflicts of interest relevant to this article. Address correspondence to Dr. J.J. Stefanik, Department of Physical Therapy, Movement, and Rehabilitation Sciences, Northeastern University, Boston, MA 02115, USA. Email: j.stefanik@northeastern.edu. Accepted for publication August 18, 2021.
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In this issue
The Journal of Rheumatology
Vol. 51, Issue 4
1 Apr 2024
Relationship of Patellofemoral Osteoarthritis to Changes in Performance-based Physical Function Over 7 Years: The Multicenter Osteoarthritis Study
Harvi F. Hart, Tuhina Neogi, Michael LaValley, Daniel White, Yuqing Zhang, Michael C. Nevitt, James Torner, Cora E. Lewis, Joshua J. Stefanik
The Journal of Rheumatology Sep 2021, jrheum.210270; DOI: 10.3899/jrheum.210270
Relationship of Patellofemoral Osteoarthritis to Changes in Performance-based Physical Function Over 7 Years: The Multicenter Osteoarthritis Study
Harvi F. Hart, Tuhina Neogi, Michael LaValley, Daniel White, Yuqing Zhang, Michael C. Nevitt, James Torner, Cora E. Lewis, Joshua J. Stefanik
The Journal of Rheumatology Sep 2021, jrheum.210270; DOI: 10.3899/jrheum.210270