Research ArticleArticle
Current Smoking Negatively Affects the Response to Methotrexate in Rheumatoid Arthritis in a Dose-responsive Way, Independently of Concomitant Prednisone Use
Mary Safy-Khan, Maria J.H. de Hair, Paco M.J. Welsing, Jacob M. van Laar and Johannes W.G. Jacobs on behalf of the Society for Rheumatology Research Utrecht (SRU)
The Journal of Rheumatology February 2021, jrheum.200213; DOI: https://doi.org/10.3899/jrheum.200213
Mary Safy-Khan
M. Safy-Khan, MD, P.M. Welsing, PhD, J.M. van Laar, MD, PhD, Professor, J.W. Jacobs, MD, PhD, Associate Professor, Department of Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht University; M.J. de Hair, MD, PhD, Novartis Pharma BV, the Netherlands. JMvL received honoraria from MSD, Roche, Pfizer, BMS, and Eli Lilly. MSK was supported by a research grant from AstraZeneca; AstraZeneca was not involved in this study. MJdH is an employee of Novartis Pharma BV; Novartis was not involved in this study. JWGJ and PMJW report no competing interests. Address correspondence to M. Safy-Khan, PhD student, Department of Rheumatology & Clinical Immunology, G02.228, University Medical Center Utrecht, Box 85500, 3508 GA, Utrecht, the Netherlands. Email: marysafy@hotmail.com. Accepted for publication January 19, 2021.
Maria J.H. de Hair
M. Safy-Khan, MD, P.M. Welsing, PhD, J.M. van Laar, MD, PhD, Professor, J.W. Jacobs, MD, PhD, Associate Professor, Department of Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht University; M.J. de Hair, MD, PhD, Novartis Pharma BV, the Netherlands. JMvL received honoraria from MSD, Roche, Pfizer, BMS, and Eli Lilly. MSK was supported by a research grant from AstraZeneca; AstraZeneca was not involved in this study. MJdH is an employee of Novartis Pharma BV; Novartis was not involved in this study. JWGJ and PMJW report no competing interests. Address correspondence to M. Safy-Khan, PhD student, Department of Rheumatology & Clinical Immunology, G02.228, University Medical Center Utrecht, Box 85500, 3508 GA, Utrecht, the Netherlands. Email: marysafy@hotmail.com. Accepted for publication January 19, 2021.
Paco M.J. Welsing
M. Safy-Khan, MD, P.M. Welsing, PhD, J.M. van Laar, MD, PhD, Professor, J.W. Jacobs, MD, PhD, Associate Professor, Department of Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht University; M.J. de Hair, MD, PhD, Novartis Pharma BV, the Netherlands. JMvL received honoraria from MSD, Roche, Pfizer, BMS, and Eli Lilly. MSK was supported by a research grant from AstraZeneca; AstraZeneca was not involved in this study. MJdH is an employee of Novartis Pharma BV; Novartis was not involved in this study. JWGJ and PMJW report no competing interests. Address correspondence to M. Safy-Khan, PhD student, Department of Rheumatology & Clinical Immunology, G02.228, University Medical Center Utrecht, Box 85500, 3508 GA, Utrecht, the Netherlands. Email: marysafy@hotmail.com. Accepted for publication January 19, 2021.
Jacob M. van Laar
M. Safy-Khan, MD, P.M. Welsing, PhD, J.M. van Laar, MD, PhD, Professor, J.W. Jacobs, MD, PhD, Associate Professor, Department of Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht University; M.J. de Hair, MD, PhD, Novartis Pharma BV, the Netherlands. JMvL received honoraria from MSD, Roche, Pfizer, BMS, and Eli Lilly. MSK was supported by a research grant from AstraZeneca; AstraZeneca was not involved in this study. MJdH is an employee of Novartis Pharma BV; Novartis was not involved in this study. JWGJ and PMJW report no competing interests. Address correspondence to M. Safy-Khan, PhD student, Department of Rheumatology & Clinical Immunology, G02.228, University Medical Center Utrecht, Box 85500, 3508 GA, Utrecht, the Netherlands. Email: marysafy@hotmail.com. Accepted for publication January 19, 2021.
Johannes W.G. Jacobs
M. Safy-Khan, MD, P.M. Welsing, PhD, J.M. van Laar, MD, PhD, Professor, J.W. Jacobs, MD, PhD, Associate Professor, Department of Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht University; M.J. de Hair, MD, PhD, Novartis Pharma BV, the Netherlands. JMvL received honoraria from MSD, Roche, Pfizer, BMS, and Eli Lilly. MSK was supported by a research grant from AstraZeneca; AstraZeneca was not involved in this study. MJdH is an employee of Novartis Pharma BV; Novartis was not involved in this study. JWGJ and PMJW report no competing interests. Address correspondence to M. Safy-Khan, PhD student, Department of Rheumatology & Clinical Immunology, G02.228, University Medical Center Utrecht, Box 85500, 3508 GA, Utrecht, the Netherlands. Email: marysafy@hotmail.com. Accepted for publication January 19, 2021.
In this issue
The Journal of Rheumatology
Vol. 51, Issue 3
1 Mar 2024
Current Smoking Negatively Affects the Response to Methotrexate in Rheumatoid Arthritis in a Dose-responsive Way, Independently of Concomitant Prednisone Use
Mary Safy-Khan, Maria J.H. de Hair, Paco M.J. Welsing, Jacob M. van Laar, Johannes W.G. Jacobs
The Journal of Rheumatology Feb 2021, jrheum.200213; DOI: 10.3899/jrheum.200213
Current Smoking Negatively Affects the Response to Methotrexate in Rheumatoid Arthritis in a Dose-responsive Way, Independently of Concomitant Prednisone Use
Mary Safy-Khan, Maria J.H. de Hair, Paco M.J. Welsing, Jacob M. van Laar, Johannes W.G. Jacobs
The Journal of Rheumatology Feb 2021, jrheum.200213; DOI: 10.3899/jrheum.200213