Research ArticleArticle
Open Access
Lifestyle and Clinical Risk Factors for Incident Rheumatoid Arthritis-associated Interstitial Lung Disease
Vanessa L. Kronzer, Weixing Huang, Paul F. Dellaripa, Sicong Huang, Vivi Feathers, Bing Lu, Christine K. Iannaccone, Ritu R. Gill, Hiroto Hatabu, Mizuki Nishino, Cynthia S. Crowson, John M. Davis III, Michael E. Weinblatt, Nancy A. Shadick, Tracy J. Doyle and Jeffrey A. Sparks
The Journal of Rheumatology November 2020, jrheum.200863; DOI: https://doi.org/10.3899/jrheum.200863
Vanessa L. Kronzer
This work was supported by the Rheumatology Research Foundation K Supplement Award; National Institutes of Health (NIH; grant numbers K23 AR069688, K23 HL119558, R03 AR075886, R03 HL148484, L30 AR066953, P30 AR070253, and P30 AR072577); and the R. Bruce and Joan M. Mickey Research Scholar Fund. The Brigham Rheumatoid Arthritis Sequential Study is funded by grants from Bristol-Myers Squibb, Crescendo Bioscience, and Sanofi. The funders had no role in study design, data collection, analysis, decision to publish, or preparation of the manuscript. The content is solely the responsibility of the authors and does not necessarily represent the official views of Harvard University, its affiliated academic health care centers, or the NIH. V.L. Kronzer, MD, MSCI, J.M. Davis III, MD, MS, Division of Rheumatology, Mayo Clinic, Rochester, Minnesota; W. Huang, MSPH, P.F. Dellaripa, MD, S. Huang, MD, MS, V. Feathers, MS, B. Lu, MD, DrPH, M.E. Weinblatt, MD, N.A. Shadick, MD, MPH, J.A. Sparks, MD, MMSc, Division of Rheumatology, Inflammation, and Immunity, Brigham and Women’s Hospital and Harvard Medical School, Boston; C.K. Iannaccone, MPH, Division of General Internal Medicine, Brigham and Women’s Hospital, Boston; R.R. Gill, MD, MPH, Department of Radiology, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston; H. Hatabu, MD, PhD, Department of Radiology, Brigham and Women’s Hospital, Boston; M. Nishino, MD, Department of Radiology, Brigham and Women’s Hospital, and Department of Imaging, Dana-Farber Cancer Institute, Boston; C.S. Crowson, PhD, Division of Rheumatology, Mayo Clinic, Rochester, and Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota; T.J. Doyle, MD, MPH, Division of Pulmonary and Critical Care; Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, USA. T.J. Doyle and J.A. Sparks contributed equally to this manuscript. The authors declare no conflicts of interest. Address correspondence to Dr. J.A. Sparks, 60 Fenwood Road, Boston, MA 02115, USA. Email: jsparks@bwh.harvard.edu. Full Release Article. For details see Reprints and Permissions at jrheum.org. Accepted October 23, 2020.
Weixing Huang
This work was supported by the Rheumatology Research Foundation K Supplement Award; National Institutes of Health (NIH; grant numbers K23 AR069688, K23 HL119558, R03 AR075886, R03 HL148484, L30 AR066953, P30 AR070253, and P30 AR072577); and the R. Bruce and Joan M. Mickey Research Scholar Fund. The Brigham Rheumatoid Arthritis Sequential Study is funded by grants from Bristol-Myers Squibb, Crescendo Bioscience, and Sanofi. The funders had no role in study design, data collection, analysis, decision to publish, or preparation of the manuscript. The content is solely the responsibility of the authors and does not necessarily represent the official views of Harvard University, its affiliated academic health care centers, or the NIH. V.L. Kronzer, MD, MSCI, J.M. Davis III, MD, MS, Division of Rheumatology, Mayo Clinic, Rochester, Minnesota; W. Huang, MSPH, P.F. Dellaripa, MD, S. Huang, MD, MS, V. Feathers, MS, B. Lu, MD, DrPH, M.E. Weinblatt, MD, N.A. Shadick, MD, MPH, J.A. Sparks, MD, MMSc, Division of Rheumatology, Inflammation, and Immunity, Brigham and Women’s Hospital and Harvard Medical School, Boston; C.K. Iannaccone, MPH, Division of General Internal Medicine, Brigham and Women’s Hospital, Boston; R.R. Gill, MD, MPH, Department of Radiology, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston; H. Hatabu, MD, PhD, Department of Radiology, Brigham and Women’s Hospital, Boston; M. Nishino, MD, Department of Radiology, Brigham and Women’s Hospital, and Department of Imaging, Dana-Farber Cancer Institute, Boston; C.S. Crowson, PhD, Division of Rheumatology, Mayo Clinic, Rochester, and Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota; T.J. Doyle, MD, MPH, Division of Pulmonary and Critical Care; Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, USA. T.J. Doyle and J.A. Sparks contributed equally to this manuscript. The authors declare no conflicts of interest. Address correspondence to Dr. J.A. Sparks, 60 Fenwood Road, Boston, MA 02115, USA. Email: jsparks@bwh.harvard.edu. Full Release Article. For details see Reprints and Permissions at jrheum.org. Accepted October 23, 2020.
Paul F. Dellaripa
This work was supported by the Rheumatology Research Foundation K Supplement Award; National Institutes of Health (NIH; grant numbers K23 AR069688, K23 HL119558, R03 AR075886, R03 HL148484, L30 AR066953, P30 AR070253, and P30 AR072577); and the R. Bruce and Joan M. Mickey Research Scholar Fund. The Brigham Rheumatoid Arthritis Sequential Study is funded by grants from Bristol-Myers Squibb, Crescendo Bioscience, and Sanofi. The funders had no role in study design, data collection, analysis, decision to publish, or preparation of the manuscript. The content is solely the responsibility of the authors and does not necessarily represent the official views of Harvard University, its affiliated academic health care centers, or the NIH. V.L. Kronzer, MD, MSCI, J.M. Davis III, MD, MS, Division of Rheumatology, Mayo Clinic, Rochester, Minnesota; W. Huang, MSPH, P.F. Dellaripa, MD, S. Huang, MD, MS, V. Feathers, MS, B. Lu, MD, DrPH, M.E. Weinblatt, MD, N.A. Shadick, MD, MPH, J.A. Sparks, MD, MMSc, Division of Rheumatology, Inflammation, and Immunity, Brigham and Women’s Hospital and Harvard Medical School, Boston; C.K. Iannaccone, MPH, Division of General Internal Medicine, Brigham and Women’s Hospital, Boston; R.R. Gill, MD, MPH, Department of Radiology, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston; H. Hatabu, MD, PhD, Department of Radiology, Brigham and Women’s Hospital, Boston; M. Nishino, MD, Department of Radiology, Brigham and Women’s Hospital, and Department of Imaging, Dana-Farber Cancer Institute, Boston; C.S. Crowson, PhD, Division of Rheumatology, Mayo Clinic, Rochester, and Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota; T.J. Doyle, MD, MPH, Division of Pulmonary and Critical Care; Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, USA. T.J. Doyle and J.A. Sparks contributed equally to this manuscript. The authors declare no conflicts of interest. Address correspondence to Dr. J.A. Sparks, 60 Fenwood Road, Boston, MA 02115, USA. Email: jsparks@bwh.harvard.edu. Full Release Article. For details see Reprints and Permissions at jrheum.org. Accepted October 23, 2020.
Sicong Huang
This work was supported by the Rheumatology Research Foundation K Supplement Award; National Institutes of Health (NIH; grant numbers K23 AR069688, K23 HL119558, R03 AR075886, R03 HL148484, L30 AR066953, P30 AR070253, and P30 AR072577); and the R. Bruce and Joan M. Mickey Research Scholar Fund. The Brigham Rheumatoid Arthritis Sequential Study is funded by grants from Bristol-Myers Squibb, Crescendo Bioscience, and Sanofi. The funders had no role in study design, data collection, analysis, decision to publish, or preparation of the manuscript. The content is solely the responsibility of the authors and does not necessarily represent the official views of Harvard University, its affiliated academic health care centers, or the NIH. V.L. Kronzer, MD, MSCI, J.M. Davis III, MD, MS, Division of Rheumatology, Mayo Clinic, Rochester, Minnesota; W. Huang, MSPH, P.F. Dellaripa, MD, S. Huang, MD, MS, V. Feathers, MS, B. Lu, MD, DrPH, M.E. Weinblatt, MD, N.A. Shadick, MD, MPH, J.A. Sparks, MD, MMSc, Division of Rheumatology, Inflammation, and Immunity, Brigham and Women’s Hospital and Harvard Medical School, Boston; C.K. Iannaccone, MPH, Division of General Internal Medicine, Brigham and Women’s Hospital, Boston; R.R. Gill, MD, MPH, Department of Radiology, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston; H. Hatabu, MD, PhD, Department of Radiology, Brigham and Women’s Hospital, Boston; M. Nishino, MD, Department of Radiology, Brigham and Women’s Hospital, and Department of Imaging, Dana-Farber Cancer Institute, Boston; C.S. Crowson, PhD, Division of Rheumatology, Mayo Clinic, Rochester, and Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota; T.J. Doyle, MD, MPH, Division of Pulmonary and Critical Care; Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, USA. T.J. Doyle and J.A. Sparks contributed equally to this manuscript. The authors declare no conflicts of interest. Address correspondence to Dr. J.A. Sparks, 60 Fenwood Road, Boston, MA 02115, USA. Email: jsparks@bwh.harvard.edu. Full Release Article. For details see Reprints and Permissions at jrheum.org. Accepted October 23, 2020.
Vivi Feathers
This work was supported by the Rheumatology Research Foundation K Supplement Award; National Institutes of Health (NIH; grant numbers K23 AR069688, K23 HL119558, R03 AR075886, R03 HL148484, L30 AR066953, P30 AR070253, and P30 AR072577); and the R. Bruce and Joan M. Mickey Research Scholar Fund. The Brigham Rheumatoid Arthritis Sequential Study is funded by grants from Bristol-Myers Squibb, Crescendo Bioscience, and Sanofi. The funders had no role in study design, data collection, analysis, decision to publish, or preparation of the manuscript. The content is solely the responsibility of the authors and does not necessarily represent the official views of Harvard University, its affiliated academic health care centers, or the NIH. V.L. Kronzer, MD, MSCI, J.M. Davis III, MD, MS, Division of Rheumatology, Mayo Clinic, Rochester, Minnesota; W. Huang, MSPH, P.F. Dellaripa, MD, S. Huang, MD, MS, V. Feathers, MS, B. Lu, MD, DrPH, M.E. Weinblatt, MD, N.A. Shadick, MD, MPH, J.A. Sparks, MD, MMSc, Division of Rheumatology, Inflammation, and Immunity, Brigham and Women’s Hospital and Harvard Medical School, Boston; C.K. Iannaccone, MPH, Division of General Internal Medicine, Brigham and Women’s Hospital, Boston; R.R. Gill, MD, MPH, Department of Radiology, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston; H. Hatabu, MD, PhD, Department of Radiology, Brigham and Women’s Hospital, Boston; M. Nishino, MD, Department of Radiology, Brigham and Women’s Hospital, and Department of Imaging, Dana-Farber Cancer Institute, Boston; C.S. Crowson, PhD, Division of Rheumatology, Mayo Clinic, Rochester, and Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota; T.J. Doyle, MD, MPH, Division of Pulmonary and Critical Care; Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, USA. T.J. Doyle and J.A. Sparks contributed equally to this manuscript. The authors declare no conflicts of interest. Address correspondence to Dr. J.A. Sparks, 60 Fenwood Road, Boston, MA 02115, USA. Email: jsparks@bwh.harvard.edu. Full Release Article. For details see Reprints and Permissions at jrheum.org. Accepted October 23, 2020.
Bing Lu
This work was supported by the Rheumatology Research Foundation K Supplement Award; National Institutes of Health (NIH; grant numbers K23 AR069688, K23 HL119558, R03 AR075886, R03 HL148484, L30 AR066953, P30 AR070253, and P30 AR072577); and the R. Bruce and Joan M. Mickey Research Scholar Fund. The Brigham Rheumatoid Arthritis Sequential Study is funded by grants from Bristol-Myers Squibb, Crescendo Bioscience, and Sanofi. The funders had no role in study design, data collection, analysis, decision to publish, or preparation of the manuscript. The content is solely the responsibility of the authors and does not necessarily represent the official views of Harvard University, its affiliated academic health care centers, or the NIH. V.L. Kronzer, MD, MSCI, J.M. Davis III, MD, MS, Division of Rheumatology, Mayo Clinic, Rochester, Minnesota; W. Huang, MSPH, P.F. Dellaripa, MD, S. Huang, MD, MS, V. Feathers, MS, B. Lu, MD, DrPH, M.E. Weinblatt, MD, N.A. Shadick, MD, MPH, J.A. Sparks, MD, MMSc, Division of Rheumatology, Inflammation, and Immunity, Brigham and Women’s Hospital and Harvard Medical School, Boston; C.K. Iannaccone, MPH, Division of General Internal Medicine, Brigham and Women’s Hospital, Boston; R.R. Gill, MD, MPH, Department of Radiology, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston; H. Hatabu, MD, PhD, Department of Radiology, Brigham and Women’s Hospital, Boston; M. Nishino, MD, Department of Radiology, Brigham and Women’s Hospital, and Department of Imaging, Dana-Farber Cancer Institute, Boston; C.S. Crowson, PhD, Division of Rheumatology, Mayo Clinic, Rochester, and Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota; T.J. Doyle, MD, MPH, Division of Pulmonary and Critical Care; Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, USA. T.J. Doyle and J.A. Sparks contributed equally to this manuscript. The authors declare no conflicts of interest. Address correspondence to Dr. J.A. Sparks, 60 Fenwood Road, Boston, MA 02115, USA. Email: jsparks@bwh.harvard.edu. Full Release Article. For details see Reprints and Permissions at jrheum.org. Accepted October 23, 2020.
Christine K. Iannaccone
This work was supported by the Rheumatology Research Foundation K Supplement Award; National Institutes of Health (NIH; grant numbers K23 AR069688, K23 HL119558, R03 AR075886, R03 HL148484, L30 AR066953, P30 AR070253, and P30 AR072577); and the R. Bruce and Joan M. Mickey Research Scholar Fund. The Brigham Rheumatoid Arthritis Sequential Study is funded by grants from Bristol-Myers Squibb, Crescendo Bioscience, and Sanofi. The funders had no role in study design, data collection, analysis, decision to publish, or preparation of the manuscript. The content is solely the responsibility of the authors and does not necessarily represent the official views of Harvard University, its affiliated academic health care centers, or the NIH. V.L. Kronzer, MD, MSCI, J.M. Davis III, MD, MS, Division of Rheumatology, Mayo Clinic, Rochester, Minnesota; W. Huang, MSPH, P.F. Dellaripa, MD, S. Huang, MD, MS, V. Feathers, MS, B. Lu, MD, DrPH, M.E. Weinblatt, MD, N.A. Shadick, MD, MPH, J.A. Sparks, MD, MMSc, Division of Rheumatology, Inflammation, and Immunity, Brigham and Women’s Hospital and Harvard Medical School, Boston; C.K. Iannaccone, MPH, Division of General Internal Medicine, Brigham and Women’s Hospital, Boston; R.R. Gill, MD, MPH, Department of Radiology, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston; H. Hatabu, MD, PhD, Department of Radiology, Brigham and Women’s Hospital, Boston; M. Nishino, MD, Department of Radiology, Brigham and Women’s Hospital, and Department of Imaging, Dana-Farber Cancer Institute, Boston; C.S. Crowson, PhD, Division of Rheumatology, Mayo Clinic, Rochester, and Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota; T.J. Doyle, MD, MPH, Division of Pulmonary and Critical Care; Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, USA. T.J. Doyle and J.A. Sparks contributed equally to this manuscript. The authors declare no conflicts of interest. Address correspondence to Dr. J.A. Sparks, 60 Fenwood Road, Boston, MA 02115, USA. Email: jsparks@bwh.harvard.edu. Full Release Article. For details see Reprints and Permissions at jrheum.org. Accepted October 23, 2020.
Ritu R. Gill
This work was supported by the Rheumatology Research Foundation K Supplement Award; National Institutes of Health (NIH; grant numbers K23 AR069688, K23 HL119558, R03 AR075886, R03 HL148484, L30 AR066953, P30 AR070253, and P30 AR072577); and the R. Bruce and Joan M. Mickey Research Scholar Fund. The Brigham Rheumatoid Arthritis Sequential Study is funded by grants from Bristol-Myers Squibb, Crescendo Bioscience, and Sanofi. The funders had no role in study design, data collection, analysis, decision to publish, or preparation of the manuscript. The content is solely the responsibility of the authors and does not necessarily represent the official views of Harvard University, its affiliated academic health care centers, or the NIH. V.L. Kronzer, MD, MSCI, J.M. Davis III, MD, MS, Division of Rheumatology, Mayo Clinic, Rochester, Minnesota; W. Huang, MSPH, P.F. Dellaripa, MD, S. Huang, MD, MS, V. Feathers, MS, B. Lu, MD, DrPH, M.E. Weinblatt, MD, N.A. Shadick, MD, MPH, J.A. Sparks, MD, MMSc, Division of Rheumatology, Inflammation, and Immunity, Brigham and Women’s Hospital and Harvard Medical School, Boston; C.K. Iannaccone, MPH, Division of General Internal Medicine, Brigham and Women’s Hospital, Boston; R.R. Gill, MD, MPH, Department of Radiology, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston; H. Hatabu, MD, PhD, Department of Radiology, Brigham and Women’s Hospital, Boston; M. Nishino, MD, Department of Radiology, Brigham and Women’s Hospital, and Department of Imaging, Dana-Farber Cancer Institute, Boston; C.S. Crowson, PhD, Division of Rheumatology, Mayo Clinic, Rochester, and Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota; T.J. Doyle, MD, MPH, Division of Pulmonary and Critical Care; Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, USA. T.J. Doyle and J.A. Sparks contributed equally to this manuscript. The authors declare no conflicts of interest. Address correspondence to Dr. J.A. Sparks, 60 Fenwood Road, Boston, MA 02115, USA. Email: jsparks@bwh.harvard.edu. Full Release Article. For details see Reprints and Permissions at jrheum.org. Accepted October 23, 2020.
Hiroto Hatabu
This work was supported by the Rheumatology Research Foundation K Supplement Award; National Institutes of Health (NIH; grant numbers K23 AR069688, K23 HL119558, R03 AR075886, R03 HL148484, L30 AR066953, P30 AR070253, and P30 AR072577); and the R. Bruce and Joan M. Mickey Research Scholar Fund. The Brigham Rheumatoid Arthritis Sequential Study is funded by grants from Bristol-Myers Squibb, Crescendo Bioscience, and Sanofi. The funders had no role in study design, data collection, analysis, decision to publish, or preparation of the manuscript. The content is solely the responsibility of the authors and does not necessarily represent the official views of Harvard University, its affiliated academic health care centers, or the NIH. V.L. Kronzer, MD, MSCI, J.M. Davis III, MD, MS, Division of Rheumatology, Mayo Clinic, Rochester, Minnesota; W. Huang, MSPH, P.F. Dellaripa, MD, S. Huang, MD, MS, V. Feathers, MS, B. Lu, MD, DrPH, M.E. Weinblatt, MD, N.A. Shadick, MD, MPH, J.A. Sparks, MD, MMSc, Division of Rheumatology, Inflammation, and Immunity, Brigham and Women’s Hospital and Harvard Medical School, Boston; C.K. Iannaccone, MPH, Division of General Internal Medicine, Brigham and Women’s Hospital, Boston; R.R. Gill, MD, MPH, Department of Radiology, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston; H. Hatabu, MD, PhD, Department of Radiology, Brigham and Women’s Hospital, Boston; M. Nishino, MD, Department of Radiology, Brigham and Women’s Hospital, and Department of Imaging, Dana-Farber Cancer Institute, Boston; C.S. Crowson, PhD, Division of Rheumatology, Mayo Clinic, Rochester, and Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota; T.J. Doyle, MD, MPH, Division of Pulmonary and Critical Care; Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, USA. T.J. Doyle and J.A. Sparks contributed equally to this manuscript. The authors declare no conflicts of interest. Address correspondence to Dr. J.A. Sparks, 60 Fenwood Road, Boston, MA 02115, USA. Email: jsparks@bwh.harvard.edu. Full Release Article. For details see Reprints and Permissions at jrheum.org. Accepted October 23, 2020.
Mizuki Nishino
This work was supported by the Rheumatology Research Foundation K Supplement Award; National Institutes of Health (NIH; grant numbers K23 AR069688, K23 HL119558, R03 AR075886, R03 HL148484, L30 AR066953, P30 AR070253, and P30 AR072577); and the R. Bruce and Joan M. Mickey Research Scholar Fund. The Brigham Rheumatoid Arthritis Sequential Study is funded by grants from Bristol-Myers Squibb, Crescendo Bioscience, and Sanofi. The funders had no role in study design, data collection, analysis, decision to publish, or preparation of the manuscript. The content is solely the responsibility of the authors and does not necessarily represent the official views of Harvard University, its affiliated academic health care centers, or the NIH. V.L. Kronzer, MD, MSCI, J.M. Davis III, MD, MS, Division of Rheumatology, Mayo Clinic, Rochester, Minnesota; W. Huang, MSPH, P.F. Dellaripa, MD, S. Huang, MD, MS, V. Feathers, MS, B. Lu, MD, DrPH, M.E. Weinblatt, MD, N.A. Shadick, MD, MPH, J.A. Sparks, MD, MMSc, Division of Rheumatology, Inflammation, and Immunity, Brigham and Women’s Hospital and Harvard Medical School, Boston; C.K. Iannaccone, MPH, Division of General Internal Medicine, Brigham and Women’s Hospital, Boston; R.R. Gill, MD, MPH, Department of Radiology, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston; H. Hatabu, MD, PhD, Department of Radiology, Brigham and Women’s Hospital, Boston; M. Nishino, MD, Department of Radiology, Brigham and Women’s Hospital, and Department of Imaging, Dana-Farber Cancer Institute, Boston; C.S. Crowson, PhD, Division of Rheumatology, Mayo Clinic, Rochester, and Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota; T.J. Doyle, MD, MPH, Division of Pulmonary and Critical Care; Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, USA. T.J. Doyle and J.A. Sparks contributed equally to this manuscript. The authors declare no conflicts of interest. Address correspondence to Dr. J.A. Sparks, 60 Fenwood Road, Boston, MA 02115, USA. Email: jsparks@bwh.harvard.edu. Full Release Article. For details see Reprints and Permissions at jrheum.org. Accepted October 23, 2020.
Cynthia S. Crowson
This work was supported by the Rheumatology Research Foundation K Supplement Award; National Institutes of Health (NIH; grant numbers K23 AR069688, K23 HL119558, R03 AR075886, R03 HL148484, L30 AR066953, P30 AR070253, and P30 AR072577); and the R. Bruce and Joan M. Mickey Research Scholar Fund. The Brigham Rheumatoid Arthritis Sequential Study is funded by grants from Bristol-Myers Squibb, Crescendo Bioscience, and Sanofi. The funders had no role in study design, data collection, analysis, decision to publish, or preparation of the manuscript. The content is solely the responsibility of the authors and does not necessarily represent the official views of Harvard University, its affiliated academic health care centers, or the NIH. V.L. Kronzer, MD, MSCI, J.M. Davis III, MD, MS, Division of Rheumatology, Mayo Clinic, Rochester, Minnesota; W. Huang, MSPH, P.F. Dellaripa, MD, S. Huang, MD, MS, V. Feathers, MS, B. Lu, MD, DrPH, M.E. Weinblatt, MD, N.A. Shadick, MD, MPH, J.A. Sparks, MD, MMSc, Division of Rheumatology, Inflammation, and Immunity, Brigham and Women’s Hospital and Harvard Medical School, Boston; C.K. Iannaccone, MPH, Division of General Internal Medicine, Brigham and Women’s Hospital, Boston; R.R. Gill, MD, MPH, Department of Radiology, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston; H. Hatabu, MD, PhD, Department of Radiology, Brigham and Women’s Hospital, Boston; M. Nishino, MD, Department of Radiology, Brigham and Women’s Hospital, and Department of Imaging, Dana-Farber Cancer Institute, Boston; C.S. Crowson, PhD, Division of Rheumatology, Mayo Clinic, Rochester, and Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota; T.J. Doyle, MD, MPH, Division of Pulmonary and Critical Care; Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, USA. T.J. Doyle and J.A. Sparks contributed equally to this manuscript. The authors declare no conflicts of interest. Address correspondence to Dr. J.A. Sparks, 60 Fenwood Road, Boston, MA 02115, USA. Email: jsparks@bwh.harvard.edu. Full Release Article. For details see Reprints and Permissions at jrheum.org. Accepted October 23, 2020.
John M. Davis III
This work was supported by the Rheumatology Research Foundation K Supplement Award; National Institutes of Health (NIH; grant numbers K23 AR069688, K23 HL119558, R03 AR075886, R03 HL148484, L30 AR066953, P30 AR070253, and P30 AR072577); and the R. Bruce and Joan M. Mickey Research Scholar Fund. The Brigham Rheumatoid Arthritis Sequential Study is funded by grants from Bristol-Myers Squibb, Crescendo Bioscience, and Sanofi. The funders had no role in study design, data collection, analysis, decision to publish, or preparation of the manuscript. The content is solely the responsibility of the authors and does not necessarily represent the official views of Harvard University, its affiliated academic health care centers, or the NIH. V.L. Kronzer, MD, MSCI, J.M. Davis III, MD, MS, Division of Rheumatology, Mayo Clinic, Rochester, Minnesota; W. Huang, MSPH, P.F. Dellaripa, MD, S. Huang, MD, MS, V. Feathers, MS, B. Lu, MD, DrPH, M.E. Weinblatt, MD, N.A. Shadick, MD, MPH, J.A. Sparks, MD, MMSc, Division of Rheumatology, Inflammation, and Immunity, Brigham and Women’s Hospital and Harvard Medical School, Boston; C.K. Iannaccone, MPH, Division of General Internal Medicine, Brigham and Women’s Hospital, Boston; R.R. Gill, MD, MPH, Department of Radiology, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston; H. Hatabu, MD, PhD, Department of Radiology, Brigham and Women’s Hospital, Boston; M. Nishino, MD, Department of Radiology, Brigham and Women’s Hospital, and Department of Imaging, Dana-Farber Cancer Institute, Boston; C.S. Crowson, PhD, Division of Rheumatology, Mayo Clinic, Rochester, and Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota; T.J. Doyle, MD, MPH, Division of Pulmonary and Critical Care; Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, USA. T.J. Doyle and J.A. Sparks contributed equally to this manuscript. The authors declare no conflicts of interest. Address correspondence to Dr. J.A. Sparks, 60 Fenwood Road, Boston, MA 02115, USA. Email: jsparks@bwh.harvard.edu. Full Release Article. For details see Reprints and Permissions at jrheum.org. Accepted October 23, 2020.
Michael E. Weinblatt
This work was supported by the Rheumatology Research Foundation K Supplement Award; National Institutes of Health (NIH; grant numbers K23 AR069688, K23 HL119558, R03 AR075886, R03 HL148484, L30 AR066953, P30 AR070253, and P30 AR072577); and the R. Bruce and Joan M. Mickey Research Scholar Fund. The Brigham Rheumatoid Arthritis Sequential Study is funded by grants from Bristol-Myers Squibb, Crescendo Bioscience, and Sanofi. The funders had no role in study design, data collection, analysis, decision to publish, or preparation of the manuscript. The content is solely the responsibility of the authors and does not necessarily represent the official views of Harvard University, its affiliated academic health care centers, or the NIH. V.L. Kronzer, MD, MSCI, J.M. Davis III, MD, MS, Division of Rheumatology, Mayo Clinic, Rochester, Minnesota; W. Huang, MSPH, P.F. Dellaripa, MD, S. Huang, MD, MS, V. Feathers, MS, B. Lu, MD, DrPH, M.E. Weinblatt, MD, N.A. Shadick, MD, MPH, J.A. Sparks, MD, MMSc, Division of Rheumatology, Inflammation, and Immunity, Brigham and Women’s Hospital and Harvard Medical School, Boston; C.K. Iannaccone, MPH, Division of General Internal Medicine, Brigham and Women’s Hospital, Boston; R.R. Gill, MD, MPH, Department of Radiology, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston; H. Hatabu, MD, PhD, Department of Radiology, Brigham and Women’s Hospital, Boston; M. Nishino, MD, Department of Radiology, Brigham and Women’s Hospital, and Department of Imaging, Dana-Farber Cancer Institute, Boston; C.S. Crowson, PhD, Division of Rheumatology, Mayo Clinic, Rochester, and Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota; T.J. Doyle, MD, MPH, Division of Pulmonary and Critical Care; Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, USA. T.J. Doyle and J.A. Sparks contributed equally to this manuscript. The authors declare no conflicts of interest. Address correspondence to Dr. J.A. Sparks, 60 Fenwood Road, Boston, MA 02115, USA. Email: jsparks@bwh.harvard.edu. Full Release Article. For details see Reprints and Permissions at jrheum.org. Accepted October 23, 2020.
Nancy A. Shadick
This work was supported by the Rheumatology Research Foundation K Supplement Award; National Institutes of Health (NIH; grant numbers K23 AR069688, K23 HL119558, R03 AR075886, R03 HL148484, L30 AR066953, P30 AR070253, and P30 AR072577); and the R. Bruce and Joan M. Mickey Research Scholar Fund. The Brigham Rheumatoid Arthritis Sequential Study is funded by grants from Bristol-Myers Squibb, Crescendo Bioscience, and Sanofi. The funders had no role in study design, data collection, analysis, decision to publish, or preparation of the manuscript. The content is solely the responsibility of the authors and does not necessarily represent the official views of Harvard University, its affiliated academic health care centers, or the NIH. V.L. Kronzer, MD, MSCI, J.M. Davis III, MD, MS, Division of Rheumatology, Mayo Clinic, Rochester, Minnesota; W. Huang, MSPH, P.F. Dellaripa, MD, S. Huang, MD, MS, V. Feathers, MS, B. Lu, MD, DrPH, M.E. Weinblatt, MD, N.A. Shadick, MD, MPH, J.A. Sparks, MD, MMSc, Division of Rheumatology, Inflammation, and Immunity, Brigham and Women’s Hospital and Harvard Medical School, Boston; C.K. Iannaccone, MPH, Division of General Internal Medicine, Brigham and Women’s Hospital, Boston; R.R. Gill, MD, MPH, Department of Radiology, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston; H. Hatabu, MD, PhD, Department of Radiology, Brigham and Women’s Hospital, Boston; M. Nishino, MD, Department of Radiology, Brigham and Women’s Hospital, and Department of Imaging, Dana-Farber Cancer Institute, Boston; C.S. Crowson, PhD, Division of Rheumatology, Mayo Clinic, Rochester, and Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota; T.J. Doyle, MD, MPH, Division of Pulmonary and Critical Care; Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, USA. T.J. Doyle and J.A. Sparks contributed equally to this manuscript. The authors declare no conflicts of interest. Address correspondence to Dr. J.A. Sparks, 60 Fenwood Road, Boston, MA 02115, USA. Email: jsparks@bwh.harvard.edu. Full Release Article. For details see Reprints and Permissions at jrheum.org. Accepted October 23, 2020.
Tracy J. Doyle
This work was supported by the Rheumatology Research Foundation K Supplement Award; National Institutes of Health (NIH; grant numbers K23 AR069688, K23 HL119558, R03 AR075886, R03 HL148484, L30 AR066953, P30 AR070253, and P30 AR072577); and the R. Bruce and Joan M. Mickey Research Scholar Fund. The Brigham Rheumatoid Arthritis Sequential Study is funded by grants from Bristol-Myers Squibb, Crescendo Bioscience, and Sanofi. The funders had no role in study design, data collection, analysis, decision to publish, or preparation of the manuscript. The content is solely the responsibility of the authors and does not necessarily represent the official views of Harvard University, its affiliated academic health care centers, or the NIH. V.L. Kronzer, MD, MSCI, J.M. Davis III, MD, MS, Division of Rheumatology, Mayo Clinic, Rochester, Minnesota; W. Huang, MSPH, P.F. Dellaripa, MD, S. Huang, MD, MS, V. Feathers, MS, B. Lu, MD, DrPH, M.E. Weinblatt, MD, N.A. Shadick, MD, MPH, J.A. Sparks, MD, MMSc, Division of Rheumatology, Inflammation, and Immunity, Brigham and Women’s Hospital and Harvard Medical School, Boston; C.K. Iannaccone, MPH, Division of General Internal Medicine, Brigham and Women’s Hospital, Boston; R.R. Gill, MD, MPH, Department of Radiology, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston; H. Hatabu, MD, PhD, Department of Radiology, Brigham and Women’s Hospital, Boston; M. Nishino, MD, Department of Radiology, Brigham and Women’s Hospital, and Department of Imaging, Dana-Farber Cancer Institute, Boston; C.S. Crowson, PhD, Division of Rheumatology, Mayo Clinic, Rochester, and Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota; T.J. Doyle, MD, MPH, Division of Pulmonary and Critical Care; Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, USA. T.J. Doyle and J.A. Sparks contributed equally to this manuscript. The authors declare no conflicts of interest. Address correspondence to Dr. J.A. Sparks, 60 Fenwood Road, Boston, MA 02115, USA. Email: jsparks@bwh.harvard.edu. Full Release Article. For details see Reprints and Permissions at jrheum.org. Accepted October 23, 2020.
Jeffrey A. Sparks
This work was supported by the Rheumatology Research Foundation K Supplement Award; National Institutes of Health (NIH; grant numbers K23 AR069688, K23 HL119558, R03 AR075886, R03 HL148484, L30 AR066953, P30 AR070253, and P30 AR072577); and the R. Bruce and Joan M. Mickey Research Scholar Fund. The Brigham Rheumatoid Arthritis Sequential Study is funded by grants from Bristol-Myers Squibb, Crescendo Bioscience, and Sanofi. The funders had no role in study design, data collection, analysis, decision to publish, or preparation of the manuscript. The content is solely the responsibility of the authors and does not necessarily represent the official views of Harvard University, its affiliated academic health care centers, or the NIH. V.L. Kronzer, MD, MSCI, J.M. Davis III, MD, MS, Division of Rheumatology, Mayo Clinic, Rochester, Minnesota; W. Huang, MSPH, P.F. Dellaripa, MD, S. Huang, MD, MS, V. Feathers, MS, B. Lu, MD, DrPH, M.E. Weinblatt, MD, N.A. Shadick, MD, MPH, J.A. Sparks, MD, MMSc, Division of Rheumatology, Inflammation, and Immunity, Brigham and Women’s Hospital and Harvard Medical School, Boston; C.K. Iannaccone, MPH, Division of General Internal Medicine, Brigham and Women’s Hospital, Boston; R.R. Gill, MD, MPH, Department of Radiology, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston; H. Hatabu, MD, PhD, Department of Radiology, Brigham and Women’s Hospital, Boston; M. Nishino, MD, Department of Radiology, Brigham and Women’s Hospital, and Department of Imaging, Dana-Farber Cancer Institute, Boston; C.S. Crowson, PhD, Division of Rheumatology, Mayo Clinic, Rochester, and Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota; T.J. Doyle, MD, MPH, Division of Pulmonary and Critical Care; Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, USA. T.J. Doyle and J.A. Sparks contributed equally to this manuscript. The authors declare no conflicts of interest. Address correspondence to Dr. J.A. Sparks, 60 Fenwood Road, Boston, MA 02115, USA. Email: jsparks@bwh.harvard.edu. Full Release Article. For details see Reprints and Permissions at jrheum.org. Accepted October 23, 2020.
In this issue
The Journal of Rheumatology
Vol. 51, Issue 4
1 Apr 2024
Lifestyle and Clinical Risk Factors for Incident Rheumatoid Arthritis-associated Interstitial Lung Disease
Vanessa L. Kronzer, Weixing Huang, Paul F. Dellaripa, Sicong Huang, Vivi Feathers, Bing Lu, Christine K. Iannaccone, Ritu R. Gill, Hiroto Hatabu, Mizuki Nishino, Cynthia S. Crowson, John M. Davis, Michael E. Weinblatt, Nancy A. Shadick, Tracy J. Doyle, Jeffrey A. Sparks
The Journal of Rheumatology Nov 2020, jrheum.200863; DOI: 10.3899/jrheum.200863
Lifestyle and Clinical Risk Factors for Incident Rheumatoid Arthritis-associated Interstitial Lung Disease
Vanessa L. Kronzer, Weixing Huang, Paul F. Dellaripa, Sicong Huang, Vivi Feathers, Bing Lu, Christine K. Iannaccone, Ritu R. Gill, Hiroto Hatabu, Mizuki Nishino, Cynthia S. Crowson, John M. Davis, Michael E. Weinblatt, Nancy A. Shadick, Tracy J. Doyle, Jeffrey A. Sparks
The Journal of Rheumatology Nov 2020, jrheum.200863; DOI: 10.3899/jrheum.200863