Skip to main content

Main menu

  • Home
  • Content
    • First Release
    • Current
    • Archives
    • Collections
    • Audiovisual Rheum
    • COVID-19 and Rheumatology
  • Resources
    • Guide for Authors
    • Submit Manuscript
    • Payment
    • Reviewers
    • Advertisers
    • Classified Ads
    • Reprints and Translations
    • Permissions
    • Meetings
    • FAQ
    • Policies
  • Subscribers
    • Subscription Information
    • Purchase Subscription
    • Your Account
    • Terms and Conditions
  • About Us
    • About Us
    • Editorial Board
    • Letter from the Editor
    • Duncan A. Gordon Award
    • Privacy/GDPR Policy
    • Accessibility
  • Contact Us
  • JRheum Supplements
  • Services

User menu

  • My Cart
  • Log In

Search

  • Advanced search
The Journal of Rheumatology
  • JRheum Supplements
  • Services
  • My Cart
  • Log In
The Journal of Rheumatology

Advanced Search

  • Home
  • Content
    • First Release
    • Current
    • Archives
    • Collections
    • Audiovisual Rheum
    • COVID-19 and Rheumatology
  • Resources
    • Guide for Authors
    • Submit Manuscript
    • Payment
    • Reviewers
    • Advertisers
    • Classified Ads
    • Reprints and Translations
    • Permissions
    • Meetings
    • FAQ
    • Policies
  • Subscribers
    • Subscription Information
    • Purchase Subscription
    • Your Account
    • Terms and Conditions
  • About Us
    • About Us
    • Editorial Board
    • Letter from the Editor
    • Duncan A. Gordon Award
    • Privacy/GDPR Policy
    • Accessibility
  • Contact Us
  • Follow jrheum on Twitter
  • Visit jrheum on Facebook
  • Follow jrheum on LinkedIn
  • Follow jrheum on YouTube
  • Follow jrheum on Instagram
  • Follow jrheum on RSS
Research ArticleArticle

Flare Rate Thresholds for Patient Assessment of Disease Activity States in Gout

William Taylor, Nicola Dalbeth, Kenneth G. Saag, Jasvinder A. Singh, Elizabeth J. Rahn, Amy S. Mudano, Yi-Hsing Chen, Ching-Tsai Lin, Paul Tan, Worawit Louthreno, Janitzia Vazquez-Mellado, Hansel Hernández-Llinas, Tuhina Neogi, Ana B. Vargas-Santos, Geraldo Castelar-Pinheiro, Rodrigo B. Chaves-Amorim, Tillman Uhlig, Hilde B. Hammer, Maxim Eliseev, Fernando Perez-Ruiz, Lorenzo Cavagna, Geraldine M. McCarthy, Lisa K. Stamp, Martijin Gerritsen, Viktoria Fana, Francisca Sivera and Angelo L. Gaffo
The Journal of Rheumatology May 2020, jrheum.191242; DOI: https://doi.org/10.3899/jrheum.191242
William Taylor
Funding for central study coordination and data analysis was provided by Ironwood Pharmaceuticals, which had had no role in the study design or in the collection, analysis, or interpretation of the data, the writing of the manuscript, or the decision to submit the manuscript for publication. Publication of this article was not contingent upon approval by Ironwood Pharmaceuticals. W. Taylor, MBChB, PhD, FRACP, FAFRM, University of Otago, Wellington, New Zealand; N. Dalbeth, MBChB, MD, FRACP, P. Tan, University of Auckland, Auckland, New Zealand; K.G. Saag, MD, MSc, E.J. Rahn, PhD, A.S. Mudano, MPH, University of Alabama at Birmingham, Birmingham, Alabama, USA; J.A. Singh, MD, MPH, A.L. Gaffo, MD, MSPH, University of Alabama at Birmingham, and Birmingham VA Medical Center, Birmingham, Alabama, USA; Y.H. Chen, MD, PhD, C.T. Lin, MD, Taichung Veterans General Hospital, Taichung, Taiwan; W. Louthreno, MD, Chiang Mai University, Chiang Mai, Thailand; J. Vazquez-Mellado, MD, PhD, H. Hernández-Llinas, MD, Hospital General de Mexico, Mexico City, Mexico; T. Neogi, MD, PhD, FRCPC, A.B. Vargas-Santos, MD, Boston University School of Medicine, Boston, Massachusetts, USA; G. Castelar-Pinheiro, MD, PhD, R.B. Chaves-Amorim, MD, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil; T. Uhlig, MD, H.B. Hammer, MD, PhD, Diakonhjemmet Hospital, Oslo, Norway; M. Eliseev, PhD, V.A. Nasonova Research Institute of Rheumatology, Moscow, Russia; F. Perez-Ruiz, MD, PhD, Servicio de Reumatologia, Baracaldo, Spain; L. Cavagna, MD, University and IRCCS Policlinico S. Matteo Foundation, Pavia, Italy; G.M. McCarthy, MD, FRCPI, Mater Misericordiae University Hospital, Dublin, Ireland; L.K. Stamp, MBChB, FRACP, PhD, University of Otago-Christchurch, Christchurch, New Zealand; M. Gerritsen, MD, PhD, Westfries Gasthuis, Hoorn, the Netherlands; V. Fana, MD, Copenhagen Center for Artritis Reserch, Righospitalet Glostrup, Denmark; 18F. Sivera, MD, PhD, Hospital General Universitario Elda, Elda, Spain. WT is a consultant for Pfizer, AstraZeneca, Abbvie, and Roche. ND receives grant/research support from AstraZeneca and Amgen; and is a consultant for Takeda, Pfizer, AstraZeneca, Horizon, and Kowa. KGS is a consultant for AstraZeneca, Horizon, Ironwood, SOBI, and Takeda. JAS has received consultant fees from Crealta/Horizon, Medisys, Fidia, UBM LLC, Trio Health, Medscape, WebMD, Clinical Care Options, Clearview Healthcare Partners, Putnam Associates, Spherix, Practice Point Communications, the National Institutes of Health, and the American College of Rheumatology (ACR); owns stock options in Amarin pharmaceuticals and Viking therapeutics; is on the speaker’s bureau of Simply Speaking; is a member of the executive of OMERACT, an organization that develops outcome measures in rheumatology and receives arms-length funding from 12 companies; serves on the FDA Arthritis Advisory Committee; is a member of the Veterans Affairs Rheumatology Field Advisory Committee; is the editor and the Director of the University of Alabama at Birmingham Cochrane Musculoskeletal Group Satellite Center on Network Meta-analysis; and previously served as a member of the following committees: member, the ACR Annual Meeting Planning Committee (AMPC) and Quality of Care Committees, the Chair of the ACR Meet-the-Professor, Workshop and Study Group Subcommittee, and the cochair of the ACR Criteria and Response Criteria subcommittee. LKS receives speaker fees from Amgen. AG is a consultant for SOBI and receives grant/research support from Amgen. Address correspondence to Associate Professor A. Gaffo, Shelby Biomedical Research Building 306, University of Alabama at Birmingham, Birmingham, AL 35294, USA. Email: agaffo@uabmc.edu. Accepted for publication April 21, 2020.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Nicola Dalbeth
Funding for central study coordination and data analysis was provided by Ironwood Pharmaceuticals, which had had no role in the study design or in the collection, analysis, or interpretation of the data, the writing of the manuscript, or the decision to submit the manuscript for publication. Publication of this article was not contingent upon approval by Ironwood Pharmaceuticals. W. Taylor, MBChB, PhD, FRACP, FAFRM, University of Otago, Wellington, New Zealand; N. Dalbeth, MBChB, MD, FRACP, P. Tan, University of Auckland, Auckland, New Zealand; K.G. Saag, MD, MSc, E.J. Rahn, PhD, A.S. Mudano, MPH, University of Alabama at Birmingham, Birmingham, Alabama, USA; J.A. Singh, MD, MPH, A.L. Gaffo, MD, MSPH, University of Alabama at Birmingham, and Birmingham VA Medical Center, Birmingham, Alabama, USA; Y.H. Chen, MD, PhD, C.T. Lin, MD, Taichung Veterans General Hospital, Taichung, Taiwan; W. Louthreno, MD, Chiang Mai University, Chiang Mai, Thailand; J. Vazquez-Mellado, MD, PhD, H. Hernández-Llinas, MD, Hospital General de Mexico, Mexico City, Mexico; T. Neogi, MD, PhD, FRCPC, A.B. Vargas-Santos, MD, Boston University School of Medicine, Boston, Massachusetts, USA; G. Castelar-Pinheiro, MD, PhD, R.B. Chaves-Amorim, MD, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil; T. Uhlig, MD, H.B. Hammer, MD, PhD, Diakonhjemmet Hospital, Oslo, Norway; M. Eliseev, PhD, V.A. Nasonova Research Institute of Rheumatology, Moscow, Russia; F. Perez-Ruiz, MD, PhD, Servicio de Reumatologia, Baracaldo, Spain; L. Cavagna, MD, University and IRCCS Policlinico S. Matteo Foundation, Pavia, Italy; G.M. McCarthy, MD, FRCPI, Mater Misericordiae University Hospital, Dublin, Ireland; L.K. Stamp, MBChB, FRACP, PhD, University of Otago-Christchurch, Christchurch, New Zealand; M. Gerritsen, MD, PhD, Westfries Gasthuis, Hoorn, the Netherlands; V. Fana, MD, Copenhagen Center for Artritis Reserch, Righospitalet Glostrup, Denmark; 18F. Sivera, MD, PhD, Hospital General Universitario Elda, Elda, Spain. WT is a consultant for Pfizer, AstraZeneca, Abbvie, and Roche. ND receives grant/research support from AstraZeneca and Amgen; and is a consultant for Takeda, Pfizer, AstraZeneca, Horizon, and Kowa. KGS is a consultant for AstraZeneca, Horizon, Ironwood, SOBI, and Takeda. JAS has received consultant fees from Crealta/Horizon, Medisys, Fidia, UBM LLC, Trio Health, Medscape, WebMD, Clinical Care Options, Clearview Healthcare Partners, Putnam Associates, Spherix, Practice Point Communications, the National Institutes of Health, and the American College of Rheumatology (ACR); owns stock options in Amarin pharmaceuticals and Viking therapeutics; is on the speaker’s bureau of Simply Speaking; is a member of the executive of OMERACT, an organization that develops outcome measures in rheumatology and receives arms-length funding from 12 companies; serves on the FDA Arthritis Advisory Committee; is a member of the Veterans Affairs Rheumatology Field Advisory Committee; is the editor and the Director of the University of Alabama at Birmingham Cochrane Musculoskeletal Group Satellite Center on Network Meta-analysis; and previously served as a member of the following committees: member, the ACR Annual Meeting Planning Committee (AMPC) and Quality of Care Committees, the Chair of the ACR Meet-the-Professor, Workshop and Study Group Subcommittee, and the cochair of the ACR Criteria and Response Criteria subcommittee. LKS receives speaker fees from Amgen. AG is a consultant for SOBI and receives grant/research support from Amgen. Address correspondence to Associate Professor A. Gaffo, Shelby Biomedical Research Building 306, University of Alabama at Birmingham, Birmingham, AL 35294, USA. Email: agaffo@uabmc.edu. Accepted for publication April 21, 2020.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Kenneth G. Saag
Funding for central study coordination and data analysis was provided by Ironwood Pharmaceuticals, which had had no role in the study design or in the collection, analysis, or interpretation of the data, the writing of the manuscript, or the decision to submit the manuscript for publication. Publication of this article was not contingent upon approval by Ironwood Pharmaceuticals. W. Taylor, MBChB, PhD, FRACP, FAFRM, University of Otago, Wellington, New Zealand; N. Dalbeth, MBChB, MD, FRACP, P. Tan, University of Auckland, Auckland, New Zealand; K.G. Saag, MD, MSc, E.J. Rahn, PhD, A.S. Mudano, MPH, University of Alabama at Birmingham, Birmingham, Alabama, USA; J.A. Singh, MD, MPH, A.L. Gaffo, MD, MSPH, University of Alabama at Birmingham, and Birmingham VA Medical Center, Birmingham, Alabama, USA; Y.H. Chen, MD, PhD, C.T. Lin, MD, Taichung Veterans General Hospital, Taichung, Taiwan; W. Louthreno, MD, Chiang Mai University, Chiang Mai, Thailand; J. Vazquez-Mellado, MD, PhD, H. Hernández-Llinas, MD, Hospital General de Mexico, Mexico City, Mexico; T. Neogi, MD, PhD, FRCPC, A.B. Vargas-Santos, MD, Boston University School of Medicine, Boston, Massachusetts, USA; G. Castelar-Pinheiro, MD, PhD, R.B. Chaves-Amorim, MD, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil; T. Uhlig, MD, H.B. Hammer, MD, PhD, Diakonhjemmet Hospital, Oslo, Norway; M. Eliseev, PhD, V.A. Nasonova Research Institute of Rheumatology, Moscow, Russia; F. Perez-Ruiz, MD, PhD, Servicio de Reumatologia, Baracaldo, Spain; L. Cavagna, MD, University and IRCCS Policlinico S. Matteo Foundation, Pavia, Italy; G.M. McCarthy, MD, FRCPI, Mater Misericordiae University Hospital, Dublin, Ireland; L.K. Stamp, MBChB, FRACP, PhD, University of Otago-Christchurch, Christchurch, New Zealand; M. Gerritsen, MD, PhD, Westfries Gasthuis, Hoorn, the Netherlands; V. Fana, MD, Copenhagen Center for Artritis Reserch, Righospitalet Glostrup, Denmark; 18F. Sivera, MD, PhD, Hospital General Universitario Elda, Elda, Spain. WT is a consultant for Pfizer, AstraZeneca, Abbvie, and Roche. ND receives grant/research support from AstraZeneca and Amgen; and is a consultant for Takeda, Pfizer, AstraZeneca, Horizon, and Kowa. KGS is a consultant for AstraZeneca, Horizon, Ironwood, SOBI, and Takeda. JAS has received consultant fees from Crealta/Horizon, Medisys, Fidia, UBM LLC, Trio Health, Medscape, WebMD, Clinical Care Options, Clearview Healthcare Partners, Putnam Associates, Spherix, Practice Point Communications, the National Institutes of Health, and the American College of Rheumatology (ACR); owns stock options in Amarin pharmaceuticals and Viking therapeutics; is on the speaker’s bureau of Simply Speaking; is a member of the executive of OMERACT, an organization that develops outcome measures in rheumatology and receives arms-length funding from 12 companies; serves on the FDA Arthritis Advisory Committee; is a member of the Veterans Affairs Rheumatology Field Advisory Committee; is the editor and the Director of the University of Alabama at Birmingham Cochrane Musculoskeletal Group Satellite Center on Network Meta-analysis; and previously served as a member of the following committees: member, the ACR Annual Meeting Planning Committee (AMPC) and Quality of Care Committees, the Chair of the ACR Meet-the-Professor, Workshop and Study Group Subcommittee, and the cochair of the ACR Criteria and Response Criteria subcommittee. LKS receives speaker fees from Amgen. AG is a consultant for SOBI and receives grant/research support from Amgen. Address correspondence to Associate Professor A. Gaffo, Shelby Biomedical Research Building 306, University of Alabama at Birmingham, Birmingham, AL 35294, USA. Email: agaffo@uabmc.edu. Accepted for publication April 21, 2020.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Jasvinder A. Singh
Funding for central study coordination and data analysis was provided by Ironwood Pharmaceuticals, which had had no role in the study design or in the collection, analysis, or interpretation of the data, the writing of the manuscript, or the decision to submit the manuscript for publication. Publication of this article was not contingent upon approval by Ironwood Pharmaceuticals. W. Taylor, MBChB, PhD, FRACP, FAFRM, University of Otago, Wellington, New Zealand; N. Dalbeth, MBChB, MD, FRACP, P. Tan, University of Auckland, Auckland, New Zealand; K.G. Saag, MD, MSc, E.J. Rahn, PhD, A.S. Mudano, MPH, University of Alabama at Birmingham, Birmingham, Alabama, USA; J.A. Singh, MD, MPH, A.L. Gaffo, MD, MSPH, University of Alabama at Birmingham, and Birmingham VA Medical Center, Birmingham, Alabama, USA; Y.H. Chen, MD, PhD, C.T. Lin, MD, Taichung Veterans General Hospital, Taichung, Taiwan; W. Louthreno, MD, Chiang Mai University, Chiang Mai, Thailand; J. Vazquez-Mellado, MD, PhD, H. Hernández-Llinas, MD, Hospital General de Mexico, Mexico City, Mexico; T. Neogi, MD, PhD, FRCPC, A.B. Vargas-Santos, MD, Boston University School of Medicine, Boston, Massachusetts, USA; G. Castelar-Pinheiro, MD, PhD, R.B. Chaves-Amorim, MD, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil; T. Uhlig, MD, H.B. Hammer, MD, PhD, Diakonhjemmet Hospital, Oslo, Norway; M. Eliseev, PhD, V.A. Nasonova Research Institute of Rheumatology, Moscow, Russia; F. Perez-Ruiz, MD, PhD, Servicio de Reumatologia, Baracaldo, Spain; L. Cavagna, MD, University and IRCCS Policlinico S. Matteo Foundation, Pavia, Italy; G.M. McCarthy, MD, FRCPI, Mater Misericordiae University Hospital, Dublin, Ireland; L.K. Stamp, MBChB, FRACP, PhD, University of Otago-Christchurch, Christchurch, New Zealand; M. Gerritsen, MD, PhD, Westfries Gasthuis, Hoorn, the Netherlands; V. Fana, MD, Copenhagen Center for Artritis Reserch, Righospitalet Glostrup, Denmark; 18F. Sivera, MD, PhD, Hospital General Universitario Elda, Elda, Spain. WT is a consultant for Pfizer, AstraZeneca, Abbvie, and Roche. ND receives grant/research support from AstraZeneca and Amgen; and is a consultant for Takeda, Pfizer, AstraZeneca, Horizon, and Kowa. KGS is a consultant for AstraZeneca, Horizon, Ironwood, SOBI, and Takeda. JAS has received consultant fees from Crealta/Horizon, Medisys, Fidia, UBM LLC, Trio Health, Medscape, WebMD, Clinical Care Options, Clearview Healthcare Partners, Putnam Associates, Spherix, Practice Point Communications, the National Institutes of Health, and the American College of Rheumatology (ACR); owns stock options in Amarin pharmaceuticals and Viking therapeutics; is on the speaker’s bureau of Simply Speaking; is a member of the executive of OMERACT, an organization that develops outcome measures in rheumatology and receives arms-length funding from 12 companies; serves on the FDA Arthritis Advisory Committee; is a member of the Veterans Affairs Rheumatology Field Advisory Committee; is the editor and the Director of the University of Alabama at Birmingham Cochrane Musculoskeletal Group Satellite Center on Network Meta-analysis; and previously served as a member of the following committees: member, the ACR Annual Meeting Planning Committee (AMPC) and Quality of Care Committees, the Chair of the ACR Meet-the-Professor, Workshop and Study Group Subcommittee, and the cochair of the ACR Criteria and Response Criteria subcommittee. LKS receives speaker fees from Amgen. AG is a consultant for SOBI and receives grant/research support from Amgen. Address correspondence to Associate Professor A. Gaffo, Shelby Biomedical Research Building 306, University of Alabama at Birmingham, Birmingham, AL 35294, USA. Email: agaffo@uabmc.edu. Accepted for publication April 21, 2020.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Elizabeth J. Rahn
Funding for central study coordination and data analysis was provided by Ironwood Pharmaceuticals, which had had no role in the study design or in the collection, analysis, or interpretation of the data, the writing of the manuscript, or the decision to submit the manuscript for publication. Publication of this article was not contingent upon approval by Ironwood Pharmaceuticals. W. Taylor, MBChB, PhD, FRACP, FAFRM, University of Otago, Wellington, New Zealand; N. Dalbeth, MBChB, MD, FRACP, P. Tan, University of Auckland, Auckland, New Zealand; K.G. Saag, MD, MSc, E.J. Rahn, PhD, A.S. Mudano, MPH, University of Alabama at Birmingham, Birmingham, Alabama, USA; J.A. Singh, MD, MPH, A.L. Gaffo, MD, MSPH, University of Alabama at Birmingham, and Birmingham VA Medical Center, Birmingham, Alabama, USA; Y.H. Chen, MD, PhD, C.T. Lin, MD, Taichung Veterans General Hospital, Taichung, Taiwan; W. Louthreno, MD, Chiang Mai University, Chiang Mai, Thailand; J. Vazquez-Mellado, MD, PhD, H. Hernández-Llinas, MD, Hospital General de Mexico, Mexico City, Mexico; T. Neogi, MD, PhD, FRCPC, A.B. Vargas-Santos, MD, Boston University School of Medicine, Boston, Massachusetts, USA; G. Castelar-Pinheiro, MD, PhD, R.B. Chaves-Amorim, MD, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil; T. Uhlig, MD, H.B. Hammer, MD, PhD, Diakonhjemmet Hospital, Oslo, Norway; M. Eliseev, PhD, V.A. Nasonova Research Institute of Rheumatology, Moscow, Russia; F. Perez-Ruiz, MD, PhD, Servicio de Reumatologia, Baracaldo, Spain; L. Cavagna, MD, University and IRCCS Policlinico S. Matteo Foundation, Pavia, Italy; G.M. McCarthy, MD, FRCPI, Mater Misericordiae University Hospital, Dublin, Ireland; L.K. Stamp, MBChB, FRACP, PhD, University of Otago-Christchurch, Christchurch, New Zealand; M. Gerritsen, MD, PhD, Westfries Gasthuis, Hoorn, the Netherlands; V. Fana, MD, Copenhagen Center for Artritis Reserch, Righospitalet Glostrup, Denmark; 18F. Sivera, MD, PhD, Hospital General Universitario Elda, Elda, Spain. WT is a consultant for Pfizer, AstraZeneca, Abbvie, and Roche. ND receives grant/research support from AstraZeneca and Amgen; and is a consultant for Takeda, Pfizer, AstraZeneca, Horizon, and Kowa. KGS is a consultant for AstraZeneca, Horizon, Ironwood, SOBI, and Takeda. JAS has received consultant fees from Crealta/Horizon, Medisys, Fidia, UBM LLC, Trio Health, Medscape, WebMD, Clinical Care Options, Clearview Healthcare Partners, Putnam Associates, Spherix, Practice Point Communications, the National Institutes of Health, and the American College of Rheumatology (ACR); owns stock options in Amarin pharmaceuticals and Viking therapeutics; is on the speaker’s bureau of Simply Speaking; is a member of the executive of OMERACT, an organization that develops outcome measures in rheumatology and receives arms-length funding from 12 companies; serves on the FDA Arthritis Advisory Committee; is a member of the Veterans Affairs Rheumatology Field Advisory Committee; is the editor and the Director of the University of Alabama at Birmingham Cochrane Musculoskeletal Group Satellite Center on Network Meta-analysis; and previously served as a member of the following committees: member, the ACR Annual Meeting Planning Committee (AMPC) and Quality of Care Committees, the Chair of the ACR Meet-the-Professor, Workshop and Study Group Subcommittee, and the cochair of the ACR Criteria and Response Criteria subcommittee. LKS receives speaker fees from Amgen. AG is a consultant for SOBI and receives grant/research support from Amgen. Address correspondence to Associate Professor A. Gaffo, Shelby Biomedical Research Building 306, University of Alabama at Birmingham, Birmingham, AL 35294, USA. Email: agaffo@uabmc.edu. Accepted for publication April 21, 2020.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Amy S. Mudano
Funding for central study coordination and data analysis was provided by Ironwood Pharmaceuticals, which had had no role in the study design or in the collection, analysis, or interpretation of the data, the writing of the manuscript, or the decision to submit the manuscript for publication. Publication of this article was not contingent upon approval by Ironwood Pharmaceuticals. W. Taylor, MBChB, PhD, FRACP, FAFRM, University of Otago, Wellington, New Zealand; N. Dalbeth, MBChB, MD, FRACP, P. Tan, University of Auckland, Auckland, New Zealand; K.G. Saag, MD, MSc, E.J. Rahn, PhD, A.S. Mudano, MPH, University of Alabama at Birmingham, Birmingham, Alabama, USA; J.A. Singh, MD, MPH, A.L. Gaffo, MD, MSPH, University of Alabama at Birmingham, and Birmingham VA Medical Center, Birmingham, Alabama, USA; Y.H. Chen, MD, PhD, C.T. Lin, MD, Taichung Veterans General Hospital, Taichung, Taiwan; W. Louthreno, MD, Chiang Mai University, Chiang Mai, Thailand; J. Vazquez-Mellado, MD, PhD, H. Hernández-Llinas, MD, Hospital General de Mexico, Mexico City, Mexico; T. Neogi, MD, PhD, FRCPC, A.B. Vargas-Santos, MD, Boston University School of Medicine, Boston, Massachusetts, USA; G. Castelar-Pinheiro, MD, PhD, R.B. Chaves-Amorim, MD, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil; T. Uhlig, MD, H.B. Hammer, MD, PhD, Diakonhjemmet Hospital, Oslo, Norway; M. Eliseev, PhD, V.A. Nasonova Research Institute of Rheumatology, Moscow, Russia; F. Perez-Ruiz, MD, PhD, Servicio de Reumatologia, Baracaldo, Spain; L. Cavagna, MD, University and IRCCS Policlinico S. Matteo Foundation, Pavia, Italy; G.M. McCarthy, MD, FRCPI, Mater Misericordiae University Hospital, Dublin, Ireland; L.K. Stamp, MBChB, FRACP, PhD, University of Otago-Christchurch, Christchurch, New Zealand; M. Gerritsen, MD, PhD, Westfries Gasthuis, Hoorn, the Netherlands; V. Fana, MD, Copenhagen Center for Artritis Reserch, Righospitalet Glostrup, Denmark; 18F. Sivera, MD, PhD, Hospital General Universitario Elda, Elda, Spain. WT is a consultant for Pfizer, AstraZeneca, Abbvie, and Roche. ND receives grant/research support from AstraZeneca and Amgen; and is a consultant for Takeda, Pfizer, AstraZeneca, Horizon, and Kowa. KGS is a consultant for AstraZeneca, Horizon, Ironwood, SOBI, and Takeda. JAS has received consultant fees from Crealta/Horizon, Medisys, Fidia, UBM LLC, Trio Health, Medscape, WebMD, Clinical Care Options, Clearview Healthcare Partners, Putnam Associates, Spherix, Practice Point Communications, the National Institutes of Health, and the American College of Rheumatology (ACR); owns stock options in Amarin pharmaceuticals and Viking therapeutics; is on the speaker’s bureau of Simply Speaking; is a member of the executive of OMERACT, an organization that develops outcome measures in rheumatology and receives arms-length funding from 12 companies; serves on the FDA Arthritis Advisory Committee; is a member of the Veterans Affairs Rheumatology Field Advisory Committee; is the editor and the Director of the University of Alabama at Birmingham Cochrane Musculoskeletal Group Satellite Center on Network Meta-analysis; and previously served as a member of the following committees: member, the ACR Annual Meeting Planning Committee (AMPC) and Quality of Care Committees, the Chair of the ACR Meet-the-Professor, Workshop and Study Group Subcommittee, and the cochair of the ACR Criteria and Response Criteria subcommittee. LKS receives speaker fees from Amgen. AG is a consultant for SOBI and receives grant/research support from Amgen. Address correspondence to Associate Professor A. Gaffo, Shelby Biomedical Research Building 306, University of Alabama at Birmingham, Birmingham, AL 35294, USA. Email: agaffo@uabmc.edu. Accepted for publication April 21, 2020.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Yi-Hsing Chen
Funding for central study coordination and data analysis was provided by Ironwood Pharmaceuticals, which had had no role in the study design or in the collection, analysis, or interpretation of the data, the writing of the manuscript, or the decision to submit the manuscript for publication. Publication of this article was not contingent upon approval by Ironwood Pharmaceuticals. W. Taylor, MBChB, PhD, FRACP, FAFRM, University of Otago, Wellington, New Zealand; N. Dalbeth, MBChB, MD, FRACP, P. Tan, University of Auckland, Auckland, New Zealand; K.G. Saag, MD, MSc, E.J. Rahn, PhD, A.S. Mudano, MPH, University of Alabama at Birmingham, Birmingham, Alabama, USA; J.A. Singh, MD, MPH, A.L. Gaffo, MD, MSPH, University of Alabama at Birmingham, and Birmingham VA Medical Center, Birmingham, Alabama, USA; Y.H. Chen, MD, PhD, C.T. Lin, MD, Taichung Veterans General Hospital, Taichung, Taiwan; W. Louthreno, MD, Chiang Mai University, Chiang Mai, Thailand; J. Vazquez-Mellado, MD, PhD, H. Hernández-Llinas, MD, Hospital General de Mexico, Mexico City, Mexico; T. Neogi, MD, PhD, FRCPC, A.B. Vargas-Santos, MD, Boston University School of Medicine, Boston, Massachusetts, USA; G. Castelar-Pinheiro, MD, PhD, R.B. Chaves-Amorim, MD, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil; T. Uhlig, MD, H.B. Hammer, MD, PhD, Diakonhjemmet Hospital, Oslo, Norway; M. Eliseev, PhD, V.A. Nasonova Research Institute of Rheumatology, Moscow, Russia; F. Perez-Ruiz, MD, PhD, Servicio de Reumatologia, Baracaldo, Spain; L. Cavagna, MD, University and IRCCS Policlinico S. Matteo Foundation, Pavia, Italy; G.M. McCarthy, MD, FRCPI, Mater Misericordiae University Hospital, Dublin, Ireland; L.K. Stamp, MBChB, FRACP, PhD, University of Otago-Christchurch, Christchurch, New Zealand; M. Gerritsen, MD, PhD, Westfries Gasthuis, Hoorn, the Netherlands; V. Fana, MD, Copenhagen Center for Artritis Reserch, Righospitalet Glostrup, Denmark; 18F. Sivera, MD, PhD, Hospital General Universitario Elda, Elda, Spain. WT is a consultant for Pfizer, AstraZeneca, Abbvie, and Roche. ND receives grant/research support from AstraZeneca and Amgen; and is a consultant for Takeda, Pfizer, AstraZeneca, Horizon, and Kowa. KGS is a consultant for AstraZeneca, Horizon, Ironwood, SOBI, and Takeda. JAS has received consultant fees from Crealta/Horizon, Medisys, Fidia, UBM LLC, Trio Health, Medscape, WebMD, Clinical Care Options, Clearview Healthcare Partners, Putnam Associates, Spherix, Practice Point Communications, the National Institutes of Health, and the American College of Rheumatology (ACR); owns stock options in Amarin pharmaceuticals and Viking therapeutics; is on the speaker’s bureau of Simply Speaking; is a member of the executive of OMERACT, an organization that develops outcome measures in rheumatology and receives arms-length funding from 12 companies; serves on the FDA Arthritis Advisory Committee; is a member of the Veterans Affairs Rheumatology Field Advisory Committee; is the editor and the Director of the University of Alabama at Birmingham Cochrane Musculoskeletal Group Satellite Center on Network Meta-analysis; and previously served as a member of the following committees: member, the ACR Annual Meeting Planning Committee (AMPC) and Quality of Care Committees, the Chair of the ACR Meet-the-Professor, Workshop and Study Group Subcommittee, and the cochair of the ACR Criteria and Response Criteria subcommittee. LKS receives speaker fees from Amgen. AG is a consultant for SOBI and receives grant/research support from Amgen. Address correspondence to Associate Professor A. Gaffo, Shelby Biomedical Research Building 306, University of Alabama at Birmingham, Birmingham, AL 35294, USA. Email: agaffo@uabmc.edu. Accepted for publication April 21, 2020.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Ching-Tsai Lin
Funding for central study coordination and data analysis was provided by Ironwood Pharmaceuticals, which had had no role in the study design or in the collection, analysis, or interpretation of the data, the writing of the manuscript, or the decision to submit the manuscript for publication. Publication of this article was not contingent upon approval by Ironwood Pharmaceuticals. W. Taylor, MBChB, PhD, FRACP, FAFRM, University of Otago, Wellington, New Zealand; N. Dalbeth, MBChB, MD, FRACP, P. Tan, University of Auckland, Auckland, New Zealand; K.G. Saag, MD, MSc, E.J. Rahn, PhD, A.S. Mudano, MPH, University of Alabama at Birmingham, Birmingham, Alabama, USA; J.A. Singh, MD, MPH, A.L. Gaffo, MD, MSPH, University of Alabama at Birmingham, and Birmingham VA Medical Center, Birmingham, Alabama, USA; Y.H. Chen, MD, PhD, C.T. Lin, MD, Taichung Veterans General Hospital, Taichung, Taiwan; W. Louthreno, MD, Chiang Mai University, Chiang Mai, Thailand; J. Vazquez-Mellado, MD, PhD, H. Hernández-Llinas, MD, Hospital General de Mexico, Mexico City, Mexico; T. Neogi, MD, PhD, FRCPC, A.B. Vargas-Santos, MD, Boston University School of Medicine, Boston, Massachusetts, USA; G. Castelar-Pinheiro, MD, PhD, R.B. Chaves-Amorim, MD, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil; T. Uhlig, MD, H.B. Hammer, MD, PhD, Diakonhjemmet Hospital, Oslo, Norway; M. Eliseev, PhD, V.A. Nasonova Research Institute of Rheumatology, Moscow, Russia; F. Perez-Ruiz, MD, PhD, Servicio de Reumatologia, Baracaldo, Spain; L. Cavagna, MD, University and IRCCS Policlinico S. Matteo Foundation, Pavia, Italy; G.M. McCarthy, MD, FRCPI, Mater Misericordiae University Hospital, Dublin, Ireland; L.K. Stamp, MBChB, FRACP, PhD, University of Otago-Christchurch, Christchurch, New Zealand; M. Gerritsen, MD, PhD, Westfries Gasthuis, Hoorn, the Netherlands; V. Fana, MD, Copenhagen Center for Artritis Reserch, Righospitalet Glostrup, Denmark; 18F. Sivera, MD, PhD, Hospital General Universitario Elda, Elda, Spain. WT is a consultant for Pfizer, AstraZeneca, Abbvie, and Roche. ND receives grant/research support from AstraZeneca and Amgen; and is a consultant for Takeda, Pfizer, AstraZeneca, Horizon, and Kowa. KGS is a consultant for AstraZeneca, Horizon, Ironwood, SOBI, and Takeda. JAS has received consultant fees from Crealta/Horizon, Medisys, Fidia, UBM LLC, Trio Health, Medscape, WebMD, Clinical Care Options, Clearview Healthcare Partners, Putnam Associates, Spherix, Practice Point Communications, the National Institutes of Health, and the American College of Rheumatology (ACR); owns stock options in Amarin pharmaceuticals and Viking therapeutics; is on the speaker’s bureau of Simply Speaking; is a member of the executive of OMERACT, an organization that develops outcome measures in rheumatology and receives arms-length funding from 12 companies; serves on the FDA Arthritis Advisory Committee; is a member of the Veterans Affairs Rheumatology Field Advisory Committee; is the editor and the Director of the University of Alabama at Birmingham Cochrane Musculoskeletal Group Satellite Center on Network Meta-analysis; and previously served as a member of the following committees: member, the ACR Annual Meeting Planning Committee (AMPC) and Quality of Care Committees, the Chair of the ACR Meet-the-Professor, Workshop and Study Group Subcommittee, and the cochair of the ACR Criteria and Response Criteria subcommittee. LKS receives speaker fees from Amgen. AG is a consultant for SOBI and receives grant/research support from Amgen. Address correspondence to Associate Professor A. Gaffo, Shelby Biomedical Research Building 306, University of Alabama at Birmingham, Birmingham, AL 35294, USA. Email: agaffo@uabmc.edu. Accepted for publication April 21, 2020.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Paul Tan
Funding for central study coordination and data analysis was provided by Ironwood Pharmaceuticals, which had had no role in the study design or in the collection, analysis, or interpretation of the data, the writing of the manuscript, or the decision to submit the manuscript for publication. Publication of this article was not contingent upon approval by Ironwood Pharmaceuticals. W. Taylor, MBChB, PhD, FRACP, FAFRM, University of Otago, Wellington, New Zealand; N. Dalbeth, MBChB, MD, FRACP, P. Tan, University of Auckland, Auckland, New Zealand; K.G. Saag, MD, MSc, E.J. Rahn, PhD, A.S. Mudano, MPH, University of Alabama at Birmingham, Birmingham, Alabama, USA; J.A. Singh, MD, MPH, A.L. Gaffo, MD, MSPH, University of Alabama at Birmingham, and Birmingham VA Medical Center, Birmingham, Alabama, USA; Y.H. Chen, MD, PhD, C.T. Lin, MD, Taichung Veterans General Hospital, Taichung, Taiwan; W. Louthreno, MD, Chiang Mai University, Chiang Mai, Thailand; J. Vazquez-Mellado, MD, PhD, H. Hernández-Llinas, MD, Hospital General de Mexico, Mexico City, Mexico; T. Neogi, MD, PhD, FRCPC, A.B. Vargas-Santos, MD, Boston University School of Medicine, Boston, Massachusetts, USA; G. Castelar-Pinheiro, MD, PhD, R.B. Chaves-Amorim, MD, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil; T. Uhlig, MD, H.B. Hammer, MD, PhD, Diakonhjemmet Hospital, Oslo, Norway; M. Eliseev, PhD, V.A. Nasonova Research Institute of Rheumatology, Moscow, Russia; F. Perez-Ruiz, MD, PhD, Servicio de Reumatologia, Baracaldo, Spain; L. Cavagna, MD, University and IRCCS Policlinico S. Matteo Foundation, Pavia, Italy; G.M. McCarthy, MD, FRCPI, Mater Misericordiae University Hospital, Dublin, Ireland; L.K. Stamp, MBChB, FRACP, PhD, University of Otago-Christchurch, Christchurch, New Zealand; M. Gerritsen, MD, PhD, Westfries Gasthuis, Hoorn, the Netherlands; V. Fana, MD, Copenhagen Center for Artritis Reserch, Righospitalet Glostrup, Denmark; 18F. Sivera, MD, PhD, Hospital General Universitario Elda, Elda, Spain. WT is a consultant for Pfizer, AstraZeneca, Abbvie, and Roche. ND receives grant/research support from AstraZeneca and Amgen; and is a consultant for Takeda, Pfizer, AstraZeneca, Horizon, and Kowa. KGS is a consultant for AstraZeneca, Horizon, Ironwood, SOBI, and Takeda. JAS has received consultant fees from Crealta/Horizon, Medisys, Fidia, UBM LLC, Trio Health, Medscape, WebMD, Clinical Care Options, Clearview Healthcare Partners, Putnam Associates, Spherix, Practice Point Communications, the National Institutes of Health, and the American College of Rheumatology (ACR); owns stock options in Amarin pharmaceuticals and Viking therapeutics; is on the speaker’s bureau of Simply Speaking; is a member of the executive of OMERACT, an organization that develops outcome measures in rheumatology and receives arms-length funding from 12 companies; serves on the FDA Arthritis Advisory Committee; is a member of the Veterans Affairs Rheumatology Field Advisory Committee; is the editor and the Director of the University of Alabama at Birmingham Cochrane Musculoskeletal Group Satellite Center on Network Meta-analysis; and previously served as a member of the following committees: member, the ACR Annual Meeting Planning Committee (AMPC) and Quality of Care Committees, the Chair of the ACR Meet-the-Professor, Workshop and Study Group Subcommittee, and the cochair of the ACR Criteria and Response Criteria subcommittee. LKS receives speaker fees from Amgen. AG is a consultant for SOBI and receives grant/research support from Amgen. Address correspondence to Associate Professor A. Gaffo, Shelby Biomedical Research Building 306, University of Alabama at Birmingham, Birmingham, AL 35294, USA. Email: agaffo@uabmc.edu. Accepted for publication April 21, 2020.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Worawit Louthreno
Funding for central study coordination and data analysis was provided by Ironwood Pharmaceuticals, which had had no role in the study design or in the collection, analysis, or interpretation of the data, the writing of the manuscript, or the decision to submit the manuscript for publication. Publication of this article was not contingent upon approval by Ironwood Pharmaceuticals. W. Taylor, MBChB, PhD, FRACP, FAFRM, University of Otago, Wellington, New Zealand; N. Dalbeth, MBChB, MD, FRACP, P. Tan, University of Auckland, Auckland, New Zealand; K.G. Saag, MD, MSc, E.J. Rahn, PhD, A.S. Mudano, MPH, University of Alabama at Birmingham, Birmingham, Alabama, USA; J.A. Singh, MD, MPH, A.L. Gaffo, MD, MSPH, University of Alabama at Birmingham, and Birmingham VA Medical Center, Birmingham, Alabama, USA; Y.H. Chen, MD, PhD, C.T. Lin, MD, Taichung Veterans General Hospital, Taichung, Taiwan; W. Louthreno, MD, Chiang Mai University, Chiang Mai, Thailand; J. Vazquez-Mellado, MD, PhD, H. Hernández-Llinas, MD, Hospital General de Mexico, Mexico City, Mexico; T. Neogi, MD, PhD, FRCPC, A.B. Vargas-Santos, MD, Boston University School of Medicine, Boston, Massachusetts, USA; G. Castelar-Pinheiro, MD, PhD, R.B. Chaves-Amorim, MD, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil; T. Uhlig, MD, H.B. Hammer, MD, PhD, Diakonhjemmet Hospital, Oslo, Norway; M. Eliseev, PhD, V.A. Nasonova Research Institute of Rheumatology, Moscow, Russia; F. Perez-Ruiz, MD, PhD, Servicio de Reumatologia, Baracaldo, Spain; L. Cavagna, MD, University and IRCCS Policlinico S. Matteo Foundation, Pavia, Italy; G.M. McCarthy, MD, FRCPI, Mater Misericordiae University Hospital, Dublin, Ireland; L.K. Stamp, MBChB, FRACP, PhD, University of Otago-Christchurch, Christchurch, New Zealand; M. Gerritsen, MD, PhD, Westfries Gasthuis, Hoorn, the Netherlands; V. Fana, MD, Copenhagen Center for Artritis Reserch, Righospitalet Glostrup, Denmark; 18F. Sivera, MD, PhD, Hospital General Universitario Elda, Elda, Spain. WT is a consultant for Pfizer, AstraZeneca, Abbvie, and Roche. ND receives grant/research support from AstraZeneca and Amgen; and is a consultant for Takeda, Pfizer, AstraZeneca, Horizon, and Kowa. KGS is a consultant for AstraZeneca, Horizon, Ironwood, SOBI, and Takeda. JAS has received consultant fees from Crealta/Horizon, Medisys, Fidia, UBM LLC, Trio Health, Medscape, WebMD, Clinical Care Options, Clearview Healthcare Partners, Putnam Associates, Spherix, Practice Point Communications, the National Institutes of Health, and the American College of Rheumatology (ACR); owns stock options in Amarin pharmaceuticals and Viking therapeutics; is on the speaker’s bureau of Simply Speaking; is a member of the executive of OMERACT, an organization that develops outcome measures in rheumatology and receives arms-length funding from 12 companies; serves on the FDA Arthritis Advisory Committee; is a member of the Veterans Affairs Rheumatology Field Advisory Committee; is the editor and the Director of the University of Alabama at Birmingham Cochrane Musculoskeletal Group Satellite Center on Network Meta-analysis; and previously served as a member of the following committees: member, the ACR Annual Meeting Planning Committee (AMPC) and Quality of Care Committees, the Chair of the ACR Meet-the-Professor, Workshop and Study Group Subcommittee, and the cochair of the ACR Criteria and Response Criteria subcommittee. LKS receives speaker fees from Amgen. AG is a consultant for SOBI and receives grant/research support from Amgen. Address correspondence to Associate Professor A. Gaffo, Shelby Biomedical Research Building 306, University of Alabama at Birmingham, Birmingham, AL 35294, USA. Email: agaffo@uabmc.edu. Accepted for publication April 21, 2020.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Janitzia Vazquez-Mellado
Funding for central study coordination and data analysis was provided by Ironwood Pharmaceuticals, which had had no role in the study design or in the collection, analysis, or interpretation of the data, the writing of the manuscript, or the decision to submit the manuscript for publication. Publication of this article was not contingent upon approval by Ironwood Pharmaceuticals. W. Taylor, MBChB, PhD, FRACP, FAFRM, University of Otago, Wellington, New Zealand; N. Dalbeth, MBChB, MD, FRACP, P. Tan, University of Auckland, Auckland, New Zealand; K.G. Saag, MD, MSc, E.J. Rahn, PhD, A.S. Mudano, MPH, University of Alabama at Birmingham, Birmingham, Alabama, USA; J.A. Singh, MD, MPH, A.L. Gaffo, MD, MSPH, University of Alabama at Birmingham, and Birmingham VA Medical Center, Birmingham, Alabama, USA; Y.H. Chen, MD, PhD, C.T. Lin, MD, Taichung Veterans General Hospital, Taichung, Taiwan; W. Louthreno, MD, Chiang Mai University, Chiang Mai, Thailand; J. Vazquez-Mellado, MD, PhD, H. Hernández-Llinas, MD, Hospital General de Mexico, Mexico City, Mexico; T. Neogi, MD, PhD, FRCPC, A.B. Vargas-Santos, MD, Boston University School of Medicine, Boston, Massachusetts, USA; G. Castelar-Pinheiro, MD, PhD, R.B. Chaves-Amorim, MD, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil; T. Uhlig, MD, H.B. Hammer, MD, PhD, Diakonhjemmet Hospital, Oslo, Norway; M. Eliseev, PhD, V.A. Nasonova Research Institute of Rheumatology, Moscow, Russia; F. Perez-Ruiz, MD, PhD, Servicio de Reumatologia, Baracaldo, Spain; L. Cavagna, MD, University and IRCCS Policlinico S. Matteo Foundation, Pavia, Italy; G.M. McCarthy, MD, FRCPI, Mater Misericordiae University Hospital, Dublin, Ireland; L.K. Stamp, MBChB, FRACP, PhD, University of Otago-Christchurch, Christchurch, New Zealand; M. Gerritsen, MD, PhD, Westfries Gasthuis, Hoorn, the Netherlands; V. Fana, MD, Copenhagen Center for Artritis Reserch, Righospitalet Glostrup, Denmark; 18F. Sivera, MD, PhD, Hospital General Universitario Elda, Elda, Spain. WT is a consultant for Pfizer, AstraZeneca, Abbvie, and Roche. ND receives grant/research support from AstraZeneca and Amgen; and is a consultant for Takeda, Pfizer, AstraZeneca, Horizon, and Kowa. KGS is a consultant for AstraZeneca, Horizon, Ironwood, SOBI, and Takeda. JAS has received consultant fees from Crealta/Horizon, Medisys, Fidia, UBM LLC, Trio Health, Medscape, WebMD, Clinical Care Options, Clearview Healthcare Partners, Putnam Associates, Spherix, Practice Point Communications, the National Institutes of Health, and the American College of Rheumatology (ACR); owns stock options in Amarin pharmaceuticals and Viking therapeutics; is on the speaker’s bureau of Simply Speaking; is a member of the executive of OMERACT, an organization that develops outcome measures in rheumatology and receives arms-length funding from 12 companies; serves on the FDA Arthritis Advisory Committee; is a member of the Veterans Affairs Rheumatology Field Advisory Committee; is the editor and the Director of the University of Alabama at Birmingham Cochrane Musculoskeletal Group Satellite Center on Network Meta-analysis; and previously served as a member of the following committees: member, the ACR Annual Meeting Planning Committee (AMPC) and Quality of Care Committees, the Chair of the ACR Meet-the-Professor, Workshop and Study Group Subcommittee, and the cochair of the ACR Criteria and Response Criteria subcommittee. LKS receives speaker fees from Amgen. AG is a consultant for SOBI and receives grant/research support from Amgen. Address correspondence to Associate Professor A. Gaffo, Shelby Biomedical Research Building 306, University of Alabama at Birmingham, Birmingham, AL 35294, USA. Email: agaffo@uabmc.edu. Accepted for publication April 21, 2020.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Hansel Hernández-Llinas
Funding for central study coordination and data analysis was provided by Ironwood Pharmaceuticals, which had had no role in the study design or in the collection, analysis, or interpretation of the data, the writing of the manuscript, or the decision to submit the manuscript for publication. Publication of this article was not contingent upon approval by Ironwood Pharmaceuticals. W. Taylor, MBChB, PhD, FRACP, FAFRM, University of Otago, Wellington, New Zealand; N. Dalbeth, MBChB, MD, FRACP, P. Tan, University of Auckland, Auckland, New Zealand; K.G. Saag, MD, MSc, E.J. Rahn, PhD, A.S. Mudano, MPH, University of Alabama at Birmingham, Birmingham, Alabama, USA; J.A. Singh, MD, MPH, A.L. Gaffo, MD, MSPH, University of Alabama at Birmingham, and Birmingham VA Medical Center, Birmingham, Alabama, USA; Y.H. Chen, MD, PhD, C.T. Lin, MD, Taichung Veterans General Hospital, Taichung, Taiwan; W. Louthreno, MD, Chiang Mai University, Chiang Mai, Thailand; J. Vazquez-Mellado, MD, PhD, H. Hernández-Llinas, MD, Hospital General de Mexico, Mexico City, Mexico; T. Neogi, MD, PhD, FRCPC, A.B. Vargas-Santos, MD, Boston University School of Medicine, Boston, Massachusetts, USA; G. Castelar-Pinheiro, MD, PhD, R.B. Chaves-Amorim, MD, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil; T. Uhlig, MD, H.B. Hammer, MD, PhD, Diakonhjemmet Hospital, Oslo, Norway; M. Eliseev, PhD, V.A. Nasonova Research Institute of Rheumatology, Moscow, Russia; F. Perez-Ruiz, MD, PhD, Servicio de Reumatologia, Baracaldo, Spain; L. Cavagna, MD, University and IRCCS Policlinico S. Matteo Foundation, Pavia, Italy; G.M. McCarthy, MD, FRCPI, Mater Misericordiae University Hospital, Dublin, Ireland; L.K. Stamp, MBChB, FRACP, PhD, University of Otago-Christchurch, Christchurch, New Zealand; M. Gerritsen, MD, PhD, Westfries Gasthuis, Hoorn, the Netherlands; V. Fana, MD, Copenhagen Center for Artritis Reserch, Righospitalet Glostrup, Denmark; 18F. Sivera, MD, PhD, Hospital General Universitario Elda, Elda, Spain. WT is a consultant for Pfizer, AstraZeneca, Abbvie, and Roche. ND receives grant/research support from AstraZeneca and Amgen; and is a consultant for Takeda, Pfizer, AstraZeneca, Horizon, and Kowa. KGS is a consultant for AstraZeneca, Horizon, Ironwood, SOBI, and Takeda. JAS has received consultant fees from Crealta/Horizon, Medisys, Fidia, UBM LLC, Trio Health, Medscape, WebMD, Clinical Care Options, Clearview Healthcare Partners, Putnam Associates, Spherix, Practice Point Communications, the National Institutes of Health, and the American College of Rheumatology (ACR); owns stock options in Amarin pharmaceuticals and Viking therapeutics; is on the speaker’s bureau of Simply Speaking; is a member of the executive of OMERACT, an organization that develops outcome measures in rheumatology and receives arms-length funding from 12 companies; serves on the FDA Arthritis Advisory Committee; is a member of the Veterans Affairs Rheumatology Field Advisory Committee; is the editor and the Director of the University of Alabama at Birmingham Cochrane Musculoskeletal Group Satellite Center on Network Meta-analysis; and previously served as a member of the following committees: member, the ACR Annual Meeting Planning Committee (AMPC) and Quality of Care Committees, the Chair of the ACR Meet-the-Professor, Workshop and Study Group Subcommittee, and the cochair of the ACR Criteria and Response Criteria subcommittee. LKS receives speaker fees from Amgen. AG is a consultant for SOBI and receives grant/research support from Amgen. Address correspondence to Associate Professor A. Gaffo, Shelby Biomedical Research Building 306, University of Alabama at Birmingham, Birmingham, AL 35294, USA. Email: agaffo@uabmc.edu. Accepted for publication April 21, 2020.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Tuhina Neogi
Funding for central study coordination and data analysis was provided by Ironwood Pharmaceuticals, which had had no role in the study design or in the collection, analysis, or interpretation of the data, the writing of the manuscript, or the decision to submit the manuscript for publication. Publication of this article was not contingent upon approval by Ironwood Pharmaceuticals. W. Taylor, MBChB, PhD, FRACP, FAFRM, University of Otago, Wellington, New Zealand; N. Dalbeth, MBChB, MD, FRACP, P. Tan, University of Auckland, Auckland, New Zealand; K.G. Saag, MD, MSc, E.J. Rahn, PhD, A.S. Mudano, MPH, University of Alabama at Birmingham, Birmingham, Alabama, USA; J.A. Singh, MD, MPH, A.L. Gaffo, MD, MSPH, University of Alabama at Birmingham, and Birmingham VA Medical Center, Birmingham, Alabama, USA; Y.H. Chen, MD, PhD, C.T. Lin, MD, Taichung Veterans General Hospital, Taichung, Taiwan; W. Louthreno, MD, Chiang Mai University, Chiang Mai, Thailand; J. Vazquez-Mellado, MD, PhD, H. Hernández-Llinas, MD, Hospital General de Mexico, Mexico City, Mexico; T. Neogi, MD, PhD, FRCPC, A.B. Vargas-Santos, MD, Boston University School of Medicine, Boston, Massachusetts, USA; G. Castelar-Pinheiro, MD, PhD, R.B. Chaves-Amorim, MD, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil; T. Uhlig, MD, H.B. Hammer, MD, PhD, Diakonhjemmet Hospital, Oslo, Norway; M. Eliseev, PhD, V.A. Nasonova Research Institute of Rheumatology, Moscow, Russia; F. Perez-Ruiz, MD, PhD, Servicio de Reumatologia, Baracaldo, Spain; L. Cavagna, MD, University and IRCCS Policlinico S. Matteo Foundation, Pavia, Italy; G.M. McCarthy, MD, FRCPI, Mater Misericordiae University Hospital, Dublin, Ireland; L.K. Stamp, MBChB, FRACP, PhD, University of Otago-Christchurch, Christchurch, New Zealand; M. Gerritsen, MD, PhD, Westfries Gasthuis, Hoorn, the Netherlands; V. Fana, MD, Copenhagen Center for Artritis Reserch, Righospitalet Glostrup, Denmark; 18F. Sivera, MD, PhD, Hospital General Universitario Elda, Elda, Spain. WT is a consultant for Pfizer, AstraZeneca, Abbvie, and Roche. ND receives grant/research support from AstraZeneca and Amgen; and is a consultant for Takeda, Pfizer, AstraZeneca, Horizon, and Kowa. KGS is a consultant for AstraZeneca, Horizon, Ironwood, SOBI, and Takeda. JAS has received consultant fees from Crealta/Horizon, Medisys, Fidia, UBM LLC, Trio Health, Medscape, WebMD, Clinical Care Options, Clearview Healthcare Partners, Putnam Associates, Spherix, Practice Point Communications, the National Institutes of Health, and the American College of Rheumatology (ACR); owns stock options in Amarin pharmaceuticals and Viking therapeutics; is on the speaker’s bureau of Simply Speaking; is a member of the executive of OMERACT, an organization that develops outcome measures in rheumatology and receives arms-length funding from 12 companies; serves on the FDA Arthritis Advisory Committee; is a member of the Veterans Affairs Rheumatology Field Advisory Committee; is the editor and the Director of the University of Alabama at Birmingham Cochrane Musculoskeletal Group Satellite Center on Network Meta-analysis; and previously served as a member of the following committees: member, the ACR Annual Meeting Planning Committee (AMPC) and Quality of Care Committees, the Chair of the ACR Meet-the-Professor, Workshop and Study Group Subcommittee, and the cochair of the ACR Criteria and Response Criteria subcommittee. LKS receives speaker fees from Amgen. AG is a consultant for SOBI and receives grant/research support from Amgen. Address correspondence to Associate Professor A. Gaffo, Shelby Biomedical Research Building 306, University of Alabama at Birmingham, Birmingham, AL 35294, USA. Email: agaffo@uabmc.edu. Accepted for publication April 21, 2020.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Tuhina Neogi
Ana B. Vargas-Santos
Funding for central study coordination and data analysis was provided by Ironwood Pharmaceuticals, which had had no role in the study design or in the collection, analysis, or interpretation of the data, the writing of the manuscript, or the decision to submit the manuscript for publication. Publication of this article was not contingent upon approval by Ironwood Pharmaceuticals. W. Taylor, MBChB, PhD, FRACP, FAFRM, University of Otago, Wellington, New Zealand; N. Dalbeth, MBChB, MD, FRACP, P. Tan, University of Auckland, Auckland, New Zealand; K.G. Saag, MD, MSc, E.J. Rahn, PhD, A.S. Mudano, MPH, University of Alabama at Birmingham, Birmingham, Alabama, USA; J.A. Singh, MD, MPH, A.L. Gaffo, MD, MSPH, University of Alabama at Birmingham, and Birmingham VA Medical Center, Birmingham, Alabama, USA; Y.H. Chen, MD, PhD, C.T. Lin, MD, Taichung Veterans General Hospital, Taichung, Taiwan; W. Louthreno, MD, Chiang Mai University, Chiang Mai, Thailand; J. Vazquez-Mellado, MD, PhD, H. Hernández-Llinas, MD, Hospital General de Mexico, Mexico City, Mexico; T. Neogi, MD, PhD, FRCPC, A.B. Vargas-Santos, MD, Boston University School of Medicine, Boston, Massachusetts, USA; G. Castelar-Pinheiro, MD, PhD, R.B. Chaves-Amorim, MD, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil; T. Uhlig, MD, H.B. Hammer, MD, PhD, Diakonhjemmet Hospital, Oslo, Norway; M. Eliseev, PhD, V.A. Nasonova Research Institute of Rheumatology, Moscow, Russia; F. Perez-Ruiz, MD, PhD, Servicio de Reumatologia, Baracaldo, Spain; L. Cavagna, MD, University and IRCCS Policlinico S. Matteo Foundation, Pavia, Italy; G.M. McCarthy, MD, FRCPI, Mater Misericordiae University Hospital, Dublin, Ireland; L.K. Stamp, MBChB, FRACP, PhD, University of Otago-Christchurch, Christchurch, New Zealand; M. Gerritsen, MD, PhD, Westfries Gasthuis, Hoorn, the Netherlands; V. Fana, MD, Copenhagen Center for Artritis Reserch, Righospitalet Glostrup, Denmark; 18F. Sivera, MD, PhD, Hospital General Universitario Elda, Elda, Spain. WT is a consultant for Pfizer, AstraZeneca, Abbvie, and Roche. ND receives grant/research support from AstraZeneca and Amgen; and is a consultant for Takeda, Pfizer, AstraZeneca, Horizon, and Kowa. KGS is a consultant for AstraZeneca, Horizon, Ironwood, SOBI, and Takeda. JAS has received consultant fees from Crealta/Horizon, Medisys, Fidia, UBM LLC, Trio Health, Medscape, WebMD, Clinical Care Options, Clearview Healthcare Partners, Putnam Associates, Spherix, Practice Point Communications, the National Institutes of Health, and the American College of Rheumatology (ACR); owns stock options in Amarin pharmaceuticals and Viking therapeutics; is on the speaker’s bureau of Simply Speaking; is a member of the executive of OMERACT, an organization that develops outcome measures in rheumatology and receives arms-length funding from 12 companies; serves on the FDA Arthritis Advisory Committee; is a member of the Veterans Affairs Rheumatology Field Advisory Committee; is the editor and the Director of the University of Alabama at Birmingham Cochrane Musculoskeletal Group Satellite Center on Network Meta-analysis; and previously served as a member of the following committees: member, the ACR Annual Meeting Planning Committee (AMPC) and Quality of Care Committees, the Chair of the ACR Meet-the-Professor, Workshop and Study Group Subcommittee, and the cochair of the ACR Criteria and Response Criteria subcommittee. LKS receives speaker fees from Amgen. AG is a consultant for SOBI and receives grant/research support from Amgen. Address correspondence to Associate Professor A. Gaffo, Shelby Biomedical Research Building 306, University of Alabama at Birmingham, Birmingham, AL 35294, USA. Email: agaffo@uabmc.edu. Accepted for publication April 21, 2020.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Ana B. Vargas-Santos
Geraldo Castelar-Pinheiro
Funding for central study coordination and data analysis was provided by Ironwood Pharmaceuticals, which had had no role in the study design or in the collection, analysis, or interpretation of the data, the writing of the manuscript, or the decision to submit the manuscript for publication. Publication of this article was not contingent upon approval by Ironwood Pharmaceuticals. W. Taylor, MBChB, PhD, FRACP, FAFRM, University of Otago, Wellington, New Zealand; N. Dalbeth, MBChB, MD, FRACP, P. Tan, University of Auckland, Auckland, New Zealand; K.G. Saag, MD, MSc, E.J. Rahn, PhD, A.S. Mudano, MPH, University of Alabama at Birmingham, Birmingham, Alabama, USA; J.A. Singh, MD, MPH, A.L. Gaffo, MD, MSPH, University of Alabama at Birmingham, and Birmingham VA Medical Center, Birmingham, Alabama, USA; Y.H. Chen, MD, PhD, C.T. Lin, MD, Taichung Veterans General Hospital, Taichung, Taiwan; W. Louthreno, MD, Chiang Mai University, Chiang Mai, Thailand; J. Vazquez-Mellado, MD, PhD, H. Hernández-Llinas, MD, Hospital General de Mexico, Mexico City, Mexico; T. Neogi, MD, PhD, FRCPC, A.B. Vargas-Santos, MD, Boston University School of Medicine, Boston, Massachusetts, USA; G. Castelar-Pinheiro, MD, PhD, R.B. Chaves-Amorim, MD, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil; T. Uhlig, MD, H.B. Hammer, MD, PhD, Diakonhjemmet Hospital, Oslo, Norway; M. Eliseev, PhD, V.A. Nasonova Research Institute of Rheumatology, Moscow, Russia; F. Perez-Ruiz, MD, PhD, Servicio de Reumatologia, Baracaldo, Spain; L. Cavagna, MD, University and IRCCS Policlinico S. Matteo Foundation, Pavia, Italy; G.M. McCarthy, MD, FRCPI, Mater Misericordiae University Hospital, Dublin, Ireland; L.K. Stamp, MBChB, FRACP, PhD, University of Otago-Christchurch, Christchurch, New Zealand; M. Gerritsen, MD, PhD, Westfries Gasthuis, Hoorn, the Netherlands; V. Fana, MD, Copenhagen Center for Artritis Reserch, Righospitalet Glostrup, Denmark; 18F. Sivera, MD, PhD, Hospital General Universitario Elda, Elda, Spain. WT is a consultant for Pfizer, AstraZeneca, Abbvie, and Roche. ND receives grant/research support from AstraZeneca and Amgen; and is a consultant for Takeda, Pfizer, AstraZeneca, Horizon, and Kowa. KGS is a consultant for AstraZeneca, Horizon, Ironwood, SOBI, and Takeda. JAS has received consultant fees from Crealta/Horizon, Medisys, Fidia, UBM LLC, Trio Health, Medscape, WebMD, Clinical Care Options, Clearview Healthcare Partners, Putnam Associates, Spherix, Practice Point Communications, the National Institutes of Health, and the American College of Rheumatology (ACR); owns stock options in Amarin pharmaceuticals and Viking therapeutics; is on the speaker’s bureau of Simply Speaking; is a member of the executive of OMERACT, an organization that develops outcome measures in rheumatology and receives arms-length funding from 12 companies; serves on the FDA Arthritis Advisory Committee; is a member of the Veterans Affairs Rheumatology Field Advisory Committee; is the editor and the Director of the University of Alabama at Birmingham Cochrane Musculoskeletal Group Satellite Center on Network Meta-analysis; and previously served as a member of the following committees: member, the ACR Annual Meeting Planning Committee (AMPC) and Quality of Care Committees, the Chair of the ACR Meet-the-Professor, Workshop and Study Group Subcommittee, and the cochair of the ACR Criteria and Response Criteria subcommittee. LKS receives speaker fees from Amgen. AG is a consultant for SOBI and receives grant/research support from Amgen. Address correspondence to Associate Professor A. Gaffo, Shelby Biomedical Research Building 306, University of Alabama at Birmingham, Birmingham, AL 35294, USA. Email: agaffo@uabmc.edu. Accepted for publication April 21, 2020.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Rodrigo B. Chaves-Amorim
Funding for central study coordination and data analysis was provided by Ironwood Pharmaceuticals, which had had no role in the study design or in the collection, analysis, or interpretation of the data, the writing of the manuscript, or the decision to submit the manuscript for publication. Publication of this article was not contingent upon approval by Ironwood Pharmaceuticals. W. Taylor, MBChB, PhD, FRACP, FAFRM, University of Otago, Wellington, New Zealand; N. Dalbeth, MBChB, MD, FRACP, P. Tan, University of Auckland, Auckland, New Zealand; K.G. Saag, MD, MSc, E.J. Rahn, PhD, A.S. Mudano, MPH, University of Alabama at Birmingham, Birmingham, Alabama, USA; J.A. Singh, MD, MPH, A.L. Gaffo, MD, MSPH, University of Alabama at Birmingham, and Birmingham VA Medical Center, Birmingham, Alabama, USA; Y.H. Chen, MD, PhD, C.T. Lin, MD, Taichung Veterans General Hospital, Taichung, Taiwan; W. Louthreno, MD, Chiang Mai University, Chiang Mai, Thailand; J. Vazquez-Mellado, MD, PhD, H. Hernández-Llinas, MD, Hospital General de Mexico, Mexico City, Mexico; T. Neogi, MD, PhD, FRCPC, A.B. Vargas-Santos, MD, Boston University School of Medicine, Boston, Massachusetts, USA; G. Castelar-Pinheiro, MD, PhD, R.B. Chaves-Amorim, MD, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil; T. Uhlig, MD, H.B. Hammer, MD, PhD, Diakonhjemmet Hospital, Oslo, Norway; M. Eliseev, PhD, V.A. Nasonova Research Institute of Rheumatology, Moscow, Russia; F. Perez-Ruiz, MD, PhD, Servicio de Reumatologia, Baracaldo, Spain; L. Cavagna, MD, University and IRCCS Policlinico S. Matteo Foundation, Pavia, Italy; G.M. McCarthy, MD, FRCPI, Mater Misericordiae University Hospital, Dublin, Ireland; L.K. Stamp, MBChB, FRACP, PhD, University of Otago-Christchurch, Christchurch, New Zealand; M. Gerritsen, MD, PhD, Westfries Gasthuis, Hoorn, the Netherlands; V. Fana, MD, Copenhagen Center for Artritis Reserch, Righospitalet Glostrup, Denmark; 18F. Sivera, MD, PhD, Hospital General Universitario Elda, Elda, Spain. WT is a consultant for Pfizer, AstraZeneca, Abbvie, and Roche. ND receives grant/research support from AstraZeneca and Amgen; and is a consultant for Takeda, Pfizer, AstraZeneca, Horizon, and Kowa. KGS is a consultant for AstraZeneca, Horizon, Ironwood, SOBI, and Takeda. JAS has received consultant fees from Crealta/Horizon, Medisys, Fidia, UBM LLC, Trio Health, Medscape, WebMD, Clinical Care Options, Clearview Healthcare Partners, Putnam Associates, Spherix, Practice Point Communications, the National Institutes of Health, and the American College of Rheumatology (ACR); owns stock options in Amarin pharmaceuticals and Viking therapeutics; is on the speaker’s bureau of Simply Speaking; is a member of the executive of OMERACT, an organization that develops outcome measures in rheumatology and receives arms-length funding from 12 companies; serves on the FDA Arthritis Advisory Committee; is a member of the Veterans Affairs Rheumatology Field Advisory Committee; is the editor and the Director of the University of Alabama at Birmingham Cochrane Musculoskeletal Group Satellite Center on Network Meta-analysis; and previously served as a member of the following committees: member, the ACR Annual Meeting Planning Committee (AMPC) and Quality of Care Committees, the Chair of the ACR Meet-the-Professor, Workshop and Study Group Subcommittee, and the cochair of the ACR Criteria and Response Criteria subcommittee. LKS receives speaker fees from Amgen. AG is a consultant for SOBI and receives grant/research support from Amgen. Address correspondence to Associate Professor A. Gaffo, Shelby Biomedical Research Building 306, University of Alabama at Birmingham, Birmingham, AL 35294, USA. Email: agaffo@uabmc.edu. Accepted for publication April 21, 2020.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Tillman Uhlig
Funding for central study coordination and data analysis was provided by Ironwood Pharmaceuticals, which had had no role in the study design or in the collection, analysis, or interpretation of the data, the writing of the manuscript, or the decision to submit the manuscript for publication. Publication of this article was not contingent upon approval by Ironwood Pharmaceuticals. W. Taylor, MBChB, PhD, FRACP, FAFRM, University of Otago, Wellington, New Zealand; N. Dalbeth, MBChB, MD, FRACP, P. Tan, University of Auckland, Auckland, New Zealand; K.G. Saag, MD, MSc, E.J. Rahn, PhD, A.S. Mudano, MPH, University of Alabama at Birmingham, Birmingham, Alabama, USA; J.A. Singh, MD, MPH, A.L. Gaffo, MD, MSPH, University of Alabama at Birmingham, and Birmingham VA Medical Center, Birmingham, Alabama, USA; Y.H. Chen, MD, PhD, C.T. Lin, MD, Taichung Veterans General Hospital, Taichung, Taiwan; W. Louthreno, MD, Chiang Mai University, Chiang Mai, Thailand; J. Vazquez-Mellado, MD, PhD, H. Hernández-Llinas, MD, Hospital General de Mexico, Mexico City, Mexico; T. Neogi, MD, PhD, FRCPC, A.B. Vargas-Santos, MD, Boston University School of Medicine, Boston, Massachusetts, USA; G. Castelar-Pinheiro, MD, PhD, R.B. Chaves-Amorim, MD, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil; T. Uhlig, MD, H.B. Hammer, MD, PhD, Diakonhjemmet Hospital, Oslo, Norway; M. Eliseev, PhD, V.A. Nasonova Research Institute of Rheumatology, Moscow, Russia; F. Perez-Ruiz, MD, PhD, Servicio de Reumatologia, Baracaldo, Spain; L. Cavagna, MD, University and IRCCS Policlinico S. Matteo Foundation, Pavia, Italy; G.M. McCarthy, MD, FRCPI, Mater Misericordiae University Hospital, Dublin, Ireland; L.K. Stamp, MBChB, FRACP, PhD, University of Otago-Christchurch, Christchurch, New Zealand; M. Gerritsen, MD, PhD, Westfries Gasthuis, Hoorn, the Netherlands; V. Fana, MD, Copenhagen Center for Artritis Reserch, Righospitalet Glostrup, Denmark; 18F. Sivera, MD, PhD, Hospital General Universitario Elda, Elda, Spain. WT is a consultant for Pfizer, AstraZeneca, Abbvie, and Roche. ND receives grant/research support from AstraZeneca and Amgen; and is a consultant for Takeda, Pfizer, AstraZeneca, Horizon, and Kowa. KGS is a consultant for AstraZeneca, Horizon, Ironwood, SOBI, and Takeda. JAS has received consultant fees from Crealta/Horizon, Medisys, Fidia, UBM LLC, Trio Health, Medscape, WebMD, Clinical Care Options, Clearview Healthcare Partners, Putnam Associates, Spherix, Practice Point Communications, the National Institutes of Health, and the American College of Rheumatology (ACR); owns stock options in Amarin pharmaceuticals and Viking therapeutics; is on the speaker’s bureau of Simply Speaking; is a member of the executive of OMERACT, an organization that develops outcome measures in rheumatology and receives arms-length funding from 12 companies; serves on the FDA Arthritis Advisory Committee; is a member of the Veterans Affairs Rheumatology Field Advisory Committee; is the editor and the Director of the University of Alabama at Birmingham Cochrane Musculoskeletal Group Satellite Center on Network Meta-analysis; and previously served as a member of the following committees: member, the ACR Annual Meeting Planning Committee (AMPC) and Quality of Care Committees, the Chair of the ACR Meet-the-Professor, Workshop and Study Group Subcommittee, and the cochair of the ACR Criteria and Response Criteria subcommittee. LKS receives speaker fees from Amgen. AG is a consultant for SOBI and receives grant/research support from Amgen. Address correspondence to Associate Professor A. Gaffo, Shelby Biomedical Research Building 306, University of Alabama at Birmingham, Birmingham, AL 35294, USA. Email: agaffo@uabmc.edu. Accepted for publication April 21, 2020.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Hilde B. Hammer
Funding for central study coordination and data analysis was provided by Ironwood Pharmaceuticals, which had had no role in the study design or in the collection, analysis, or interpretation of the data, the writing of the manuscript, or the decision to submit the manuscript for publication. Publication of this article was not contingent upon approval by Ironwood Pharmaceuticals. W. Taylor, MBChB, PhD, FRACP, FAFRM, University of Otago, Wellington, New Zealand; N. Dalbeth, MBChB, MD, FRACP, P. Tan, University of Auckland, Auckland, New Zealand; K.G. Saag, MD, MSc, E.J. Rahn, PhD, A.S. Mudano, MPH, University of Alabama at Birmingham, Birmingham, Alabama, USA; J.A. Singh, MD, MPH, A.L. Gaffo, MD, MSPH, University of Alabama at Birmingham, and Birmingham VA Medical Center, Birmingham, Alabama, USA; Y.H. Chen, MD, PhD, C.T. Lin, MD, Taichung Veterans General Hospital, Taichung, Taiwan; W. Louthreno, MD, Chiang Mai University, Chiang Mai, Thailand; J. Vazquez-Mellado, MD, PhD, H. Hernández-Llinas, MD, Hospital General de Mexico, Mexico City, Mexico; T. Neogi, MD, PhD, FRCPC, A.B. Vargas-Santos, MD, Boston University School of Medicine, Boston, Massachusetts, USA; G. Castelar-Pinheiro, MD, PhD, R.B. Chaves-Amorim, MD, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil; T. Uhlig, MD, H.B. Hammer, MD, PhD, Diakonhjemmet Hospital, Oslo, Norway; M. Eliseev, PhD, V.A. Nasonova Research Institute of Rheumatology, Moscow, Russia; F. Perez-Ruiz, MD, PhD, Servicio de Reumatologia, Baracaldo, Spain; L. Cavagna, MD, University and IRCCS Policlinico S. Matteo Foundation, Pavia, Italy; G.M. McCarthy, MD, FRCPI, Mater Misericordiae University Hospital, Dublin, Ireland; L.K. Stamp, MBChB, FRACP, PhD, University of Otago-Christchurch, Christchurch, New Zealand; M. Gerritsen, MD, PhD, Westfries Gasthuis, Hoorn, the Netherlands; V. Fana, MD, Copenhagen Center for Artritis Reserch, Righospitalet Glostrup, Denmark; 18F. Sivera, MD, PhD, Hospital General Universitario Elda, Elda, Spain. WT is a consultant for Pfizer, AstraZeneca, Abbvie, and Roche. ND receives grant/research support from AstraZeneca and Amgen; and is a consultant for Takeda, Pfizer, AstraZeneca, Horizon, and Kowa. KGS is a consultant for AstraZeneca, Horizon, Ironwood, SOBI, and Takeda. JAS has received consultant fees from Crealta/Horizon, Medisys, Fidia, UBM LLC, Trio Health, Medscape, WebMD, Clinical Care Options, Clearview Healthcare Partners, Putnam Associates, Spherix, Practice Point Communications, the National Institutes of Health, and the American College of Rheumatology (ACR); owns stock options in Amarin pharmaceuticals and Viking therapeutics; is on the speaker’s bureau of Simply Speaking; is a member of the executive of OMERACT, an organization that develops outcome measures in rheumatology and receives arms-length funding from 12 companies; serves on the FDA Arthritis Advisory Committee; is a member of the Veterans Affairs Rheumatology Field Advisory Committee; is the editor and the Director of the University of Alabama at Birmingham Cochrane Musculoskeletal Group Satellite Center on Network Meta-analysis; and previously served as a member of the following committees: member, the ACR Annual Meeting Planning Committee (AMPC) and Quality of Care Committees, the Chair of the ACR Meet-the-Professor, Workshop and Study Group Subcommittee, and the cochair of the ACR Criteria and Response Criteria subcommittee. LKS receives speaker fees from Amgen. AG is a consultant for SOBI and receives grant/research support from Amgen. Address correspondence to Associate Professor A. Gaffo, Shelby Biomedical Research Building 306, University of Alabama at Birmingham, Birmingham, AL 35294, USA. Email: agaffo@uabmc.edu. Accepted for publication April 21, 2020.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Maxim Eliseev
Funding for central study coordination and data analysis was provided by Ironwood Pharmaceuticals, which had had no role in the study design or in the collection, analysis, or interpretation of the data, the writing of the manuscript, or the decision to submit the manuscript for publication. Publication of this article was not contingent upon approval by Ironwood Pharmaceuticals. W. Taylor, MBChB, PhD, FRACP, FAFRM, University of Otago, Wellington, New Zealand; N. Dalbeth, MBChB, MD, FRACP, P. Tan, University of Auckland, Auckland, New Zealand; K.G. Saag, MD, MSc, E.J. Rahn, PhD, A.S. Mudano, MPH, University of Alabama at Birmingham, Birmingham, Alabama, USA; J.A. Singh, MD, MPH, A.L. Gaffo, MD, MSPH, University of Alabama at Birmingham, and Birmingham VA Medical Center, Birmingham, Alabama, USA; Y.H. Chen, MD, PhD, C.T. Lin, MD, Taichung Veterans General Hospital, Taichung, Taiwan; W. Louthreno, MD, Chiang Mai University, Chiang Mai, Thailand; J. Vazquez-Mellado, MD, PhD, H. Hernández-Llinas, MD, Hospital General de Mexico, Mexico City, Mexico; T. Neogi, MD, PhD, FRCPC, A.B. Vargas-Santos, MD, Boston University School of Medicine, Boston, Massachusetts, USA; G. Castelar-Pinheiro, MD, PhD, R.B. Chaves-Amorim, MD, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil; T. Uhlig, MD, H.B. Hammer, MD, PhD, Diakonhjemmet Hospital, Oslo, Norway; M. Eliseev, PhD, V.A. Nasonova Research Institute of Rheumatology, Moscow, Russia; F. Perez-Ruiz, MD, PhD, Servicio de Reumatologia, Baracaldo, Spain; L. Cavagna, MD, University and IRCCS Policlinico S. Matteo Foundation, Pavia, Italy; G.M. McCarthy, MD, FRCPI, Mater Misericordiae University Hospital, Dublin, Ireland; L.K. Stamp, MBChB, FRACP, PhD, University of Otago-Christchurch, Christchurch, New Zealand; M. Gerritsen, MD, PhD, Westfries Gasthuis, Hoorn, the Netherlands; V. Fana, MD, Copenhagen Center for Artritis Reserch, Righospitalet Glostrup, Denmark; 18F. Sivera, MD, PhD, Hospital General Universitario Elda, Elda, Spain. WT is a consultant for Pfizer, AstraZeneca, Abbvie, and Roche. ND receives grant/research support from AstraZeneca and Amgen; and is a consultant for Takeda, Pfizer, AstraZeneca, Horizon, and Kowa. KGS is a consultant for AstraZeneca, Horizon, Ironwood, SOBI, and Takeda. JAS has received consultant fees from Crealta/Horizon, Medisys, Fidia, UBM LLC, Trio Health, Medscape, WebMD, Clinical Care Options, Clearview Healthcare Partners, Putnam Associates, Spherix, Practice Point Communications, the National Institutes of Health, and the American College of Rheumatology (ACR); owns stock options in Amarin pharmaceuticals and Viking therapeutics; is on the speaker’s bureau of Simply Speaking; is a member of the executive of OMERACT, an organization that develops outcome measures in rheumatology and receives arms-length funding from 12 companies; serves on the FDA Arthritis Advisory Committee; is a member of the Veterans Affairs Rheumatology Field Advisory Committee; is the editor and the Director of the University of Alabama at Birmingham Cochrane Musculoskeletal Group Satellite Center on Network Meta-analysis; and previously served as a member of the following committees: member, the ACR Annual Meeting Planning Committee (AMPC) and Quality of Care Committees, the Chair of the ACR Meet-the-Professor, Workshop and Study Group Subcommittee, and the cochair of the ACR Criteria and Response Criteria subcommittee. LKS receives speaker fees from Amgen. AG is a consultant for SOBI and receives grant/research support from Amgen. Address correspondence to Associate Professor A. Gaffo, Shelby Biomedical Research Building 306, University of Alabama at Birmingham, Birmingham, AL 35294, USA. Email: agaffo@uabmc.edu. Accepted for publication April 21, 2020.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Fernando Perez-Ruiz
Funding for central study coordination and data analysis was provided by Ironwood Pharmaceuticals, which had had no role in the study design or in the collection, analysis, or interpretation of the data, the writing of the manuscript, or the decision to submit the manuscript for publication. Publication of this article was not contingent upon approval by Ironwood Pharmaceuticals. W. Taylor, MBChB, PhD, FRACP, FAFRM, University of Otago, Wellington, New Zealand; N. Dalbeth, MBChB, MD, FRACP, P. Tan, University of Auckland, Auckland, New Zealand; K.G. Saag, MD, MSc, E.J. Rahn, PhD, A.S. Mudano, MPH, University of Alabama at Birmingham, Birmingham, Alabama, USA; J.A. Singh, MD, MPH, A.L. Gaffo, MD, MSPH, University of Alabama at Birmingham, and Birmingham VA Medical Center, Birmingham, Alabama, USA; Y.H. Chen, MD, PhD, C.T. Lin, MD, Taichung Veterans General Hospital, Taichung, Taiwan; W. Louthreno, MD, Chiang Mai University, Chiang Mai, Thailand; J. Vazquez-Mellado, MD, PhD, H. Hernández-Llinas, MD, Hospital General de Mexico, Mexico City, Mexico; T. Neogi, MD, PhD, FRCPC, A.B. Vargas-Santos, MD, Boston University School of Medicine, Boston, Massachusetts, USA; G. Castelar-Pinheiro, MD, PhD, R.B. Chaves-Amorim, MD, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil; T. Uhlig, MD, H.B. Hammer, MD, PhD, Diakonhjemmet Hospital, Oslo, Norway; M. Eliseev, PhD, V.A. Nasonova Research Institute of Rheumatology, Moscow, Russia; F. Perez-Ruiz, MD, PhD, Servicio de Reumatologia, Baracaldo, Spain; L. Cavagna, MD, University and IRCCS Policlinico S. Matteo Foundation, Pavia, Italy; G.M. McCarthy, MD, FRCPI, Mater Misericordiae University Hospital, Dublin, Ireland; L.K. Stamp, MBChB, FRACP, PhD, University of Otago-Christchurch, Christchurch, New Zealand; M. Gerritsen, MD, PhD, Westfries Gasthuis, Hoorn, the Netherlands; V. Fana, MD, Copenhagen Center for Artritis Reserch, Righospitalet Glostrup, Denmark; 18F. Sivera, MD, PhD, Hospital General Universitario Elda, Elda, Spain. WT is a consultant for Pfizer, AstraZeneca, Abbvie, and Roche. ND receives grant/research support from AstraZeneca and Amgen; and is a consultant for Takeda, Pfizer, AstraZeneca, Horizon, and Kowa. KGS is a consultant for AstraZeneca, Horizon, Ironwood, SOBI, and Takeda. JAS has received consultant fees from Crealta/Horizon, Medisys, Fidia, UBM LLC, Trio Health, Medscape, WebMD, Clinical Care Options, Clearview Healthcare Partners, Putnam Associates, Spherix, Practice Point Communications, the National Institutes of Health, and the American College of Rheumatology (ACR); owns stock options in Amarin pharmaceuticals and Viking therapeutics; is on the speaker’s bureau of Simply Speaking; is a member of the executive of OMERACT, an organization that develops outcome measures in rheumatology and receives arms-length funding from 12 companies; serves on the FDA Arthritis Advisory Committee; is a member of the Veterans Affairs Rheumatology Field Advisory Committee; is the editor and the Director of the University of Alabama at Birmingham Cochrane Musculoskeletal Group Satellite Center on Network Meta-analysis; and previously served as a member of the following committees: member, the ACR Annual Meeting Planning Committee (AMPC) and Quality of Care Committees, the Chair of the ACR Meet-the-Professor, Workshop and Study Group Subcommittee, and the cochair of the ACR Criteria and Response Criteria subcommittee. LKS receives speaker fees from Amgen. AG is a consultant for SOBI and receives grant/research support from Amgen. Address correspondence to Associate Professor A. Gaffo, Shelby Biomedical Research Building 306, University of Alabama at Birmingham, Birmingham, AL 35294, USA. Email: agaffo@uabmc.edu. Accepted for publication April 21, 2020.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Lorenzo Cavagna
Funding for central study coordination and data analysis was provided by Ironwood Pharmaceuticals, which had had no role in the study design or in the collection, analysis, or interpretation of the data, the writing of the manuscript, or the decision to submit the manuscript for publication. Publication of this article was not contingent upon approval by Ironwood Pharmaceuticals. W. Taylor, MBChB, PhD, FRACP, FAFRM, University of Otago, Wellington, New Zealand; N. Dalbeth, MBChB, MD, FRACP, P. Tan, University of Auckland, Auckland, New Zealand; K.G. Saag, MD, MSc, E.J. Rahn, PhD, A.S. Mudano, MPH, University of Alabama at Birmingham, Birmingham, Alabama, USA; J.A. Singh, MD, MPH, A.L. Gaffo, MD, MSPH, University of Alabama at Birmingham, and Birmingham VA Medical Center, Birmingham, Alabama, USA; Y.H. Chen, MD, PhD, C.T. Lin, MD, Taichung Veterans General Hospital, Taichung, Taiwan; W. Louthreno, MD, Chiang Mai University, Chiang Mai, Thailand; J. Vazquez-Mellado, MD, PhD, H. Hernández-Llinas, MD, Hospital General de Mexico, Mexico City, Mexico; T. Neogi, MD, PhD, FRCPC, A.B. Vargas-Santos, MD, Boston University School of Medicine, Boston, Massachusetts, USA; G. Castelar-Pinheiro, MD, PhD, R.B. Chaves-Amorim, MD, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil; T. Uhlig, MD, H.B. Hammer, MD, PhD, Diakonhjemmet Hospital, Oslo, Norway; M. Eliseev, PhD, V.A. Nasonova Research Institute of Rheumatology, Moscow, Russia; F. Perez-Ruiz, MD, PhD, Servicio de Reumatologia, Baracaldo, Spain; L. Cavagna, MD, University and IRCCS Policlinico S. Matteo Foundation, Pavia, Italy; G.M. McCarthy, MD, FRCPI, Mater Misericordiae University Hospital, Dublin, Ireland; L.K. Stamp, MBChB, FRACP, PhD, University of Otago-Christchurch, Christchurch, New Zealand; M. Gerritsen, MD, PhD, Westfries Gasthuis, Hoorn, the Netherlands; V. Fana, MD, Copenhagen Center for Artritis Reserch, Righospitalet Glostrup, Denmark; 18F. Sivera, MD, PhD, Hospital General Universitario Elda, Elda, Spain. WT is a consultant for Pfizer, AstraZeneca, Abbvie, and Roche. ND receives grant/research support from AstraZeneca and Amgen; and is a consultant for Takeda, Pfizer, AstraZeneca, Horizon, and Kowa. KGS is a consultant for AstraZeneca, Horizon, Ironwood, SOBI, and Takeda. JAS has received consultant fees from Crealta/Horizon, Medisys, Fidia, UBM LLC, Trio Health, Medscape, WebMD, Clinical Care Options, Clearview Healthcare Partners, Putnam Associates, Spherix, Practice Point Communications, the National Institutes of Health, and the American College of Rheumatology (ACR); owns stock options in Amarin pharmaceuticals and Viking therapeutics; is on the speaker’s bureau of Simply Speaking; is a member of the executive of OMERACT, an organization that develops outcome measures in rheumatology and receives arms-length funding from 12 companies; serves on the FDA Arthritis Advisory Committee; is a member of the Veterans Affairs Rheumatology Field Advisory Committee; is the editor and the Director of the University of Alabama at Birmingham Cochrane Musculoskeletal Group Satellite Center on Network Meta-analysis; and previously served as a member of the following committees: member, the ACR Annual Meeting Planning Committee (AMPC) and Quality of Care Committees, the Chair of the ACR Meet-the-Professor, Workshop and Study Group Subcommittee, and the cochair of the ACR Criteria and Response Criteria subcommittee. LKS receives speaker fees from Amgen. AG is a consultant for SOBI and receives grant/research support from Amgen. Address correspondence to Associate Professor A. Gaffo, Shelby Biomedical Research Building 306, University of Alabama at Birmingham, Birmingham, AL 35294, USA. Email: agaffo@uabmc.edu. Accepted for publication April 21, 2020.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Geraldine M. McCarthy
Funding for central study coordination and data analysis was provided by Ironwood Pharmaceuticals, which had had no role in the study design or in the collection, analysis, or interpretation of the data, the writing of the manuscript, or the decision to submit the manuscript for publication. Publication of this article was not contingent upon approval by Ironwood Pharmaceuticals. W. Taylor, MBChB, PhD, FRACP, FAFRM, University of Otago, Wellington, New Zealand; N. Dalbeth, MBChB, MD, FRACP, P. Tan, University of Auckland, Auckland, New Zealand; K.G. Saag, MD, MSc, E.J. Rahn, PhD, A.S. Mudano, MPH, University of Alabama at Birmingham, Birmingham, Alabama, USA; J.A. Singh, MD, MPH, A.L. Gaffo, MD, MSPH, University of Alabama at Birmingham, and Birmingham VA Medical Center, Birmingham, Alabama, USA; Y.H. Chen, MD, PhD, C.T. Lin, MD, Taichung Veterans General Hospital, Taichung, Taiwan; W. Louthreno, MD, Chiang Mai University, Chiang Mai, Thailand; J. Vazquez-Mellado, MD, PhD, H. Hernández-Llinas, MD, Hospital General de Mexico, Mexico City, Mexico; T. Neogi, MD, PhD, FRCPC, A.B. Vargas-Santos, MD, Boston University School of Medicine, Boston, Massachusetts, USA; G. Castelar-Pinheiro, MD, PhD, R.B. Chaves-Amorim, MD, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil; T. Uhlig, MD, H.B. Hammer, MD, PhD, Diakonhjemmet Hospital, Oslo, Norway; M. Eliseev, PhD, V.A. Nasonova Research Institute of Rheumatology, Moscow, Russia; F. Perez-Ruiz, MD, PhD, Servicio de Reumatologia, Baracaldo, Spain; L. Cavagna, MD, University and IRCCS Policlinico S. Matteo Foundation, Pavia, Italy; G.M. McCarthy, MD, FRCPI, Mater Misericordiae University Hospital, Dublin, Ireland; L.K. Stamp, MBChB, FRACP, PhD, University of Otago-Christchurch, Christchurch, New Zealand; M. Gerritsen, MD, PhD, Westfries Gasthuis, Hoorn, the Netherlands; V. Fana, MD, Copenhagen Center for Artritis Reserch, Righospitalet Glostrup, Denmark; 18F. Sivera, MD, PhD, Hospital General Universitario Elda, Elda, Spain. WT is a consultant for Pfizer, AstraZeneca, Abbvie, and Roche. ND receives grant/research support from AstraZeneca and Amgen; and is a consultant for Takeda, Pfizer, AstraZeneca, Horizon, and Kowa. KGS is a consultant for AstraZeneca, Horizon, Ironwood, SOBI, and Takeda. JAS has received consultant fees from Crealta/Horizon, Medisys, Fidia, UBM LLC, Trio Health, Medscape, WebMD, Clinical Care Options, Clearview Healthcare Partners, Putnam Associates, Spherix, Practice Point Communications, the National Institutes of Health, and the American College of Rheumatology (ACR); owns stock options in Amarin pharmaceuticals and Viking therapeutics; is on the speaker’s bureau of Simply Speaking; is a member of the executive of OMERACT, an organization that develops outcome measures in rheumatology and receives arms-length funding from 12 companies; serves on the FDA Arthritis Advisory Committee; is a member of the Veterans Affairs Rheumatology Field Advisory Committee; is the editor and the Director of the University of Alabama at Birmingham Cochrane Musculoskeletal Group Satellite Center on Network Meta-analysis; and previously served as a member of the following committees: member, the ACR Annual Meeting Planning Committee (AMPC) and Quality of Care Committees, the Chair of the ACR Meet-the-Professor, Workshop and Study Group Subcommittee, and the cochair of the ACR Criteria and Response Criteria subcommittee. LKS receives speaker fees from Amgen. AG is a consultant for SOBI and receives grant/research support from Amgen. Address correspondence to Associate Professor A. Gaffo, Shelby Biomedical Research Building 306, University of Alabama at Birmingham, Birmingham, AL 35294, USA. Email: agaffo@uabmc.edu. Accepted for publication April 21, 2020.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Lisa K. Stamp
Funding for central study coordination and data analysis was provided by Ironwood Pharmaceuticals, which had had no role in the study design or in the collection, analysis, or interpretation of the data, the writing of the manuscript, or the decision to submit the manuscript for publication. Publication of this article was not contingent upon approval by Ironwood Pharmaceuticals. W. Taylor, MBChB, PhD, FRACP, FAFRM, University of Otago, Wellington, New Zealand; N. Dalbeth, MBChB, MD, FRACP, P. Tan, University of Auckland, Auckland, New Zealand; K.G. Saag, MD, MSc, E.J. Rahn, PhD, A.S. Mudano, MPH, University of Alabama at Birmingham, Birmingham, Alabama, USA; J.A. Singh, MD, MPH, A.L. Gaffo, MD, MSPH, University of Alabama at Birmingham, and Birmingham VA Medical Center, Birmingham, Alabama, USA; Y.H. Chen, MD, PhD, C.T. Lin, MD, Taichung Veterans General Hospital, Taichung, Taiwan; W. Louthreno, MD, Chiang Mai University, Chiang Mai, Thailand; J. Vazquez-Mellado, MD, PhD, H. Hernández-Llinas, MD, Hospital General de Mexico, Mexico City, Mexico; T. Neogi, MD, PhD, FRCPC, A.B. Vargas-Santos, MD, Boston University School of Medicine, Boston, Massachusetts, USA; G. Castelar-Pinheiro, MD, PhD, R.B. Chaves-Amorim, MD, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil; T. Uhlig, MD, H.B. Hammer, MD, PhD, Diakonhjemmet Hospital, Oslo, Norway; M. Eliseev, PhD, V.A. Nasonova Research Institute of Rheumatology, Moscow, Russia; F. Perez-Ruiz, MD, PhD, Servicio de Reumatologia, Baracaldo, Spain; L. Cavagna, MD, University and IRCCS Policlinico S. Matteo Foundation, Pavia, Italy; G.M. McCarthy, MD, FRCPI, Mater Misericordiae University Hospital, Dublin, Ireland; L.K. Stamp, MBChB, FRACP, PhD, University of Otago-Christchurch, Christchurch, New Zealand; M. Gerritsen, MD, PhD, Westfries Gasthuis, Hoorn, the Netherlands; V. Fana, MD, Copenhagen Center for Artritis Reserch, Righospitalet Glostrup, Denmark; 18F. Sivera, MD, PhD, Hospital General Universitario Elda, Elda, Spain. WT is a consultant for Pfizer, AstraZeneca, Abbvie, and Roche. ND receives grant/research support from AstraZeneca and Amgen; and is a consultant for Takeda, Pfizer, AstraZeneca, Horizon, and Kowa. KGS is a consultant for AstraZeneca, Horizon, Ironwood, SOBI, and Takeda. JAS has received consultant fees from Crealta/Horizon, Medisys, Fidia, UBM LLC, Trio Health, Medscape, WebMD, Clinical Care Options, Clearview Healthcare Partners, Putnam Associates, Spherix, Practice Point Communications, the National Institutes of Health, and the American College of Rheumatology (ACR); owns stock options in Amarin pharmaceuticals and Viking therapeutics; is on the speaker’s bureau of Simply Speaking; is a member of the executive of OMERACT, an organization that develops outcome measures in rheumatology and receives arms-length funding from 12 companies; serves on the FDA Arthritis Advisory Committee; is a member of the Veterans Affairs Rheumatology Field Advisory Committee; is the editor and the Director of the University of Alabama at Birmingham Cochrane Musculoskeletal Group Satellite Center on Network Meta-analysis; and previously served as a member of the following committees: member, the ACR Annual Meeting Planning Committee (AMPC) and Quality of Care Committees, the Chair of the ACR Meet-the-Professor, Workshop and Study Group Subcommittee, and the cochair of the ACR Criteria and Response Criteria subcommittee. LKS receives speaker fees from Amgen. AG is a consultant for SOBI and receives grant/research support from Amgen. Address correspondence to Associate Professor A. Gaffo, Shelby Biomedical Research Building 306, University of Alabama at Birmingham, Birmingham, AL 35294, USA. Email: agaffo@uabmc.edu. Accepted for publication April 21, 2020.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Martijin Gerritsen
Funding for central study coordination and data analysis was provided by Ironwood Pharmaceuticals, which had had no role in the study design or in the collection, analysis, or interpretation of the data, the writing of the manuscript, or the decision to submit the manuscript for publication. Publication of this article was not contingent upon approval by Ironwood Pharmaceuticals. W. Taylor, MBChB, PhD, FRACP, FAFRM, University of Otago, Wellington, New Zealand; N. Dalbeth, MBChB, MD, FRACP, P. Tan, University of Auckland, Auckland, New Zealand; K.G. Saag, MD, MSc, E.J. Rahn, PhD, A.S. Mudano, MPH, University of Alabama at Birmingham, Birmingham, Alabama, USA; J.A. Singh, MD, MPH, A.L. Gaffo, MD, MSPH, University of Alabama at Birmingham, and Birmingham VA Medical Center, Birmingham, Alabama, USA; Y.H. Chen, MD, PhD, C.T. Lin, MD, Taichung Veterans General Hospital, Taichung, Taiwan; W. Louthreno, MD, Chiang Mai University, Chiang Mai, Thailand; J. Vazquez-Mellado, MD, PhD, H. Hernández-Llinas, MD, Hospital General de Mexico, Mexico City, Mexico; T. Neogi, MD, PhD, FRCPC, A.B. Vargas-Santos, MD, Boston University School of Medicine, Boston, Massachusetts, USA; G. Castelar-Pinheiro, MD, PhD, R.B. Chaves-Amorim, MD, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil; T. Uhlig, MD, H.B. Hammer, MD, PhD, Diakonhjemmet Hospital, Oslo, Norway; M. Eliseev, PhD, V.A. Nasonova Research Institute of Rheumatology, Moscow, Russia; F. Perez-Ruiz, MD, PhD, Servicio de Reumatologia, Baracaldo, Spain; L. Cavagna, MD, University and IRCCS Policlinico S. Matteo Foundation, Pavia, Italy; G.M. McCarthy, MD, FRCPI, Mater Misericordiae University Hospital, Dublin, Ireland; L.K. Stamp, MBChB, FRACP, PhD, University of Otago-Christchurch, Christchurch, New Zealand; M. Gerritsen, MD, PhD, Westfries Gasthuis, Hoorn, the Netherlands; V. Fana, MD, Copenhagen Center for Artritis Reserch, Righospitalet Glostrup, Denmark; 18F. Sivera, MD, PhD, Hospital General Universitario Elda, Elda, Spain. WT is a consultant for Pfizer, AstraZeneca, Abbvie, and Roche. ND receives grant/research support from AstraZeneca and Amgen; and is a consultant for Takeda, Pfizer, AstraZeneca, Horizon, and Kowa. KGS is a consultant for AstraZeneca, Horizon, Ironwood, SOBI, and Takeda. JAS has received consultant fees from Crealta/Horizon, Medisys, Fidia, UBM LLC, Trio Health, Medscape, WebMD, Clinical Care Options, Clearview Healthcare Partners, Putnam Associates, Spherix, Practice Point Communications, the National Institutes of Health, and the American College of Rheumatology (ACR); owns stock options in Amarin pharmaceuticals and Viking therapeutics; is on the speaker’s bureau of Simply Speaking; is a member of the executive of OMERACT, an organization that develops outcome measures in rheumatology and receives arms-length funding from 12 companies; serves on the FDA Arthritis Advisory Committee; is a member of the Veterans Affairs Rheumatology Field Advisory Committee; is the editor and the Director of the University of Alabama at Birmingham Cochrane Musculoskeletal Group Satellite Center on Network Meta-analysis; and previously served as a member of the following committees: member, the ACR Annual Meeting Planning Committee (AMPC) and Quality of Care Committees, the Chair of the ACR Meet-the-Professor, Workshop and Study Group Subcommittee, and the cochair of the ACR Criteria and Response Criteria subcommittee. LKS receives speaker fees from Amgen. AG is a consultant for SOBI and receives grant/research support from Amgen. Address correspondence to Associate Professor A. Gaffo, Shelby Biomedical Research Building 306, University of Alabama at Birmingham, Birmingham, AL 35294, USA. Email: agaffo@uabmc.edu. Accepted for publication April 21, 2020.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Viktoria Fana
Funding for central study coordination and data analysis was provided by Ironwood Pharmaceuticals, which had had no role in the study design or in the collection, analysis, or interpretation of the data, the writing of the manuscript, or the decision to submit the manuscript for publication. Publication of this article was not contingent upon approval by Ironwood Pharmaceuticals. W. Taylor, MBChB, PhD, FRACP, FAFRM, University of Otago, Wellington, New Zealand; N. Dalbeth, MBChB, MD, FRACP, P. Tan, University of Auckland, Auckland, New Zealand; K.G. Saag, MD, MSc, E.J. Rahn, PhD, A.S. Mudano, MPH, University of Alabama at Birmingham, Birmingham, Alabama, USA; J.A. Singh, MD, MPH, A.L. Gaffo, MD, MSPH, University of Alabama at Birmingham, and Birmingham VA Medical Center, Birmingham, Alabama, USA; Y.H. Chen, MD, PhD, C.T. Lin, MD, Taichung Veterans General Hospital, Taichung, Taiwan; W. Louthreno, MD, Chiang Mai University, Chiang Mai, Thailand; J. Vazquez-Mellado, MD, PhD, H. Hernández-Llinas, MD, Hospital General de Mexico, Mexico City, Mexico; T. Neogi, MD, PhD, FRCPC, A.B. Vargas-Santos, MD, Boston University School of Medicine, Boston, Massachusetts, USA; G. Castelar-Pinheiro, MD, PhD, R.B. Chaves-Amorim, MD, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil; T. Uhlig, MD, H.B. Hammer, MD, PhD, Diakonhjemmet Hospital, Oslo, Norway; M. Eliseev, PhD, V.A. Nasonova Research Institute of Rheumatology, Moscow, Russia; F. Perez-Ruiz, MD, PhD, Servicio de Reumatologia, Baracaldo, Spain; L. Cavagna, MD, University and IRCCS Policlinico S. Matteo Foundation, Pavia, Italy; G.M. McCarthy, MD, FRCPI, Mater Misericordiae University Hospital, Dublin, Ireland; L.K. Stamp, MBChB, FRACP, PhD, University of Otago-Christchurch, Christchurch, New Zealand; M. Gerritsen, MD, PhD, Westfries Gasthuis, Hoorn, the Netherlands; V. Fana, MD, Copenhagen Center for Artritis Reserch, Righospitalet Glostrup, Denmark; 18F. Sivera, MD, PhD, Hospital General Universitario Elda, Elda, Spain. WT is a consultant for Pfizer, AstraZeneca, Abbvie, and Roche. ND receives grant/research support from AstraZeneca and Amgen; and is a consultant for Takeda, Pfizer, AstraZeneca, Horizon, and Kowa. KGS is a consultant for AstraZeneca, Horizon, Ironwood, SOBI, and Takeda. JAS has received consultant fees from Crealta/Horizon, Medisys, Fidia, UBM LLC, Trio Health, Medscape, WebMD, Clinical Care Options, Clearview Healthcare Partners, Putnam Associates, Spherix, Practice Point Communications, the National Institutes of Health, and the American College of Rheumatology (ACR); owns stock options in Amarin pharmaceuticals and Viking therapeutics; is on the speaker’s bureau of Simply Speaking; is a member of the executive of OMERACT, an organization that develops outcome measures in rheumatology and receives arms-length funding from 12 companies; serves on the FDA Arthritis Advisory Committee; is a member of the Veterans Affairs Rheumatology Field Advisory Committee; is the editor and the Director of the University of Alabama at Birmingham Cochrane Musculoskeletal Group Satellite Center on Network Meta-analysis; and previously served as a member of the following committees: member, the ACR Annual Meeting Planning Committee (AMPC) and Quality of Care Committees, the Chair of the ACR Meet-the-Professor, Workshop and Study Group Subcommittee, and the cochair of the ACR Criteria and Response Criteria subcommittee. LKS receives speaker fees from Amgen. AG is a consultant for SOBI and receives grant/research support from Amgen. Address correspondence to Associate Professor A. Gaffo, Shelby Biomedical Research Building 306, University of Alabama at Birmingham, Birmingham, AL 35294, USA. Email: agaffo@uabmc.edu. Accepted for publication April 21, 2020.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Francisca Sivera
Funding for central study coordination and data analysis was provided by Ironwood Pharmaceuticals, which had had no role in the study design or in the collection, analysis, or interpretation of the data, the writing of the manuscript, or the decision to submit the manuscript for publication. Publication of this article was not contingent upon approval by Ironwood Pharmaceuticals. W. Taylor, MBChB, PhD, FRACP, FAFRM, University of Otago, Wellington, New Zealand; N. Dalbeth, MBChB, MD, FRACP, P. Tan, University of Auckland, Auckland, New Zealand; K.G. Saag, MD, MSc, E.J. Rahn, PhD, A.S. Mudano, MPH, University of Alabama at Birmingham, Birmingham, Alabama, USA; J.A. Singh, MD, MPH, A.L. Gaffo, MD, MSPH, University of Alabama at Birmingham, and Birmingham VA Medical Center, Birmingham, Alabama, USA; Y.H. Chen, MD, PhD, C.T. Lin, MD, Taichung Veterans General Hospital, Taichung, Taiwan; W. Louthreno, MD, Chiang Mai University, Chiang Mai, Thailand; J. Vazquez-Mellado, MD, PhD, H. Hernández-Llinas, MD, Hospital General de Mexico, Mexico City, Mexico; T. Neogi, MD, PhD, FRCPC, A.B. Vargas-Santos, MD, Boston University School of Medicine, Boston, Massachusetts, USA; G. Castelar-Pinheiro, MD, PhD, R.B. Chaves-Amorim, MD, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil; T. Uhlig, MD, H.B. Hammer, MD, PhD, Diakonhjemmet Hospital, Oslo, Norway; M. Eliseev, PhD, V.A. Nasonova Research Institute of Rheumatology, Moscow, Russia; F. Perez-Ruiz, MD, PhD, Servicio de Reumatologia, Baracaldo, Spain; L. Cavagna, MD, University and IRCCS Policlinico S. Matteo Foundation, Pavia, Italy; G.M. McCarthy, MD, FRCPI, Mater Misericordiae University Hospital, Dublin, Ireland; L.K. Stamp, MBChB, FRACP, PhD, University of Otago-Christchurch, Christchurch, New Zealand; M. Gerritsen, MD, PhD, Westfries Gasthuis, Hoorn, the Netherlands; V. Fana, MD, Copenhagen Center for Artritis Reserch, Righospitalet Glostrup, Denmark; 18F. Sivera, MD, PhD, Hospital General Universitario Elda, Elda, Spain. WT is a consultant for Pfizer, AstraZeneca, Abbvie, and Roche. ND receives grant/research support from AstraZeneca and Amgen; and is a consultant for Takeda, Pfizer, AstraZeneca, Horizon, and Kowa. KGS is a consultant for AstraZeneca, Horizon, Ironwood, SOBI, and Takeda. JAS has received consultant fees from Crealta/Horizon, Medisys, Fidia, UBM LLC, Trio Health, Medscape, WebMD, Clinical Care Options, Clearview Healthcare Partners, Putnam Associates, Spherix, Practice Point Communications, the National Institutes of Health, and the American College of Rheumatology (ACR); owns stock options in Amarin pharmaceuticals and Viking therapeutics; is on the speaker’s bureau of Simply Speaking; is a member of the executive of OMERACT, an organization that develops outcome measures in rheumatology and receives arms-length funding from 12 companies; serves on the FDA Arthritis Advisory Committee; is a member of the Veterans Affairs Rheumatology Field Advisory Committee; is the editor and the Director of the University of Alabama at Birmingham Cochrane Musculoskeletal Group Satellite Center on Network Meta-analysis; and previously served as a member of the following committees: member, the ACR Annual Meeting Planning Committee (AMPC) and Quality of Care Committees, the Chair of the ACR Meet-the-Professor, Workshop and Study Group Subcommittee, and the cochair of the ACR Criteria and Response Criteria subcommittee. LKS receives speaker fees from Amgen. AG is a consultant for SOBI and receives grant/research support from Amgen. Address correspondence to Associate Professor A. Gaffo, Shelby Biomedical Research Building 306, University of Alabama at Birmingham, Birmingham, AL 35294, USA. Email: agaffo@uabmc.edu. Accepted for publication April 21, 2020.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Francisca Sivera
Angelo L. Gaffo
Funding for central study coordination and data analysis was provided by Ironwood Pharmaceuticals, which had had no role in the study design or in the collection, analysis, or interpretation of the data, the writing of the manuscript, or the decision to submit the manuscript for publication. Publication of this article was not contingent upon approval by Ironwood Pharmaceuticals. W. Taylor, MBChB, PhD, FRACP, FAFRM, University of Otago, Wellington, New Zealand; N. Dalbeth, MBChB, MD, FRACP, P. Tan, University of Auckland, Auckland, New Zealand; K.G. Saag, MD, MSc, E.J. Rahn, PhD, A.S. Mudano, MPH, University of Alabama at Birmingham, Birmingham, Alabama, USA; J.A. Singh, MD, MPH, A.L. Gaffo, MD, MSPH, University of Alabama at Birmingham, and Birmingham VA Medical Center, Birmingham, Alabama, USA; Y.H. Chen, MD, PhD, C.T. Lin, MD, Taichung Veterans General Hospital, Taichung, Taiwan; W. Louthreno, MD, Chiang Mai University, Chiang Mai, Thailand; J. Vazquez-Mellado, MD, PhD, H. Hernández-Llinas, MD, Hospital General de Mexico, Mexico City, Mexico; T. Neogi, MD, PhD, FRCPC, A.B. Vargas-Santos, MD, Boston University School of Medicine, Boston, Massachusetts, USA; G. Castelar-Pinheiro, MD, PhD, R.B. Chaves-Amorim, MD, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil; T. Uhlig, MD, H.B. Hammer, MD, PhD, Diakonhjemmet Hospital, Oslo, Norway; M. Eliseev, PhD, V.A. Nasonova Research Institute of Rheumatology, Moscow, Russia; F. Perez-Ruiz, MD, PhD, Servicio de Reumatologia, Baracaldo, Spain; L. Cavagna, MD, University and IRCCS Policlinico S. Matteo Foundation, Pavia, Italy; G.M. McCarthy, MD, FRCPI, Mater Misericordiae University Hospital, Dublin, Ireland; L.K. Stamp, MBChB, FRACP, PhD, University of Otago-Christchurch, Christchurch, New Zealand; M. Gerritsen, MD, PhD, Westfries Gasthuis, Hoorn, the Netherlands; V. Fana, MD, Copenhagen Center for Artritis Reserch, Righospitalet Glostrup, Denmark; 18F. Sivera, MD, PhD, Hospital General Universitario Elda, Elda, Spain. WT is a consultant for Pfizer, AstraZeneca, Abbvie, and Roche. ND receives grant/research support from AstraZeneca and Amgen; and is a consultant for Takeda, Pfizer, AstraZeneca, Horizon, and Kowa. KGS is a consultant for AstraZeneca, Horizon, Ironwood, SOBI, and Takeda. JAS has received consultant fees from Crealta/Horizon, Medisys, Fidia, UBM LLC, Trio Health, Medscape, WebMD, Clinical Care Options, Clearview Healthcare Partners, Putnam Associates, Spherix, Practice Point Communications, the National Institutes of Health, and the American College of Rheumatology (ACR); owns stock options in Amarin pharmaceuticals and Viking therapeutics; is on the speaker’s bureau of Simply Speaking; is a member of the executive of OMERACT, an organization that develops outcome measures in rheumatology and receives arms-length funding from 12 companies; serves on the FDA Arthritis Advisory Committee; is a member of the Veterans Affairs Rheumatology Field Advisory Committee; is the editor and the Director of the University of Alabama at Birmingham Cochrane Musculoskeletal Group Satellite Center on Network Meta-analysis; and previously served as a member of the following committees: member, the ACR Annual Meeting Planning Committee (AMPC) and Quality of Care Committees, the Chair of the ACR Meet-the-Professor, Workshop and Study Group Subcommittee, and the cochair of the ACR Criteria and Response Criteria subcommittee. LKS receives speaker fees from Amgen. AG is a consultant for SOBI and receives grant/research support from Amgen. Address correspondence to Associate Professor A. Gaffo, Shelby Biomedical Research Building 306, University of Alabama at Birmingham, Birmingham, AL 35294, USA. Email: agaffo@uabmc.edu. Accepted for publication April 21, 2020.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Angelo L. Gaffo
  • Article
  • Figures & Data
  • Supplemental
  • Info & Metrics
  • References
  • PDF
  • eLetters
Next
Loading

Data supplements

    • 191242DataSuppl.pdf
Next
Back to top

In this issue

The Journal of Rheumatology
Vol. 50, Issue 2
1 Feb 2023
  • Table of Contents
  • Table of Contents (PDF)
  • Index by Author
  • Editorial Board (PDF)
Download PDF
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for your interest in spreading the word about The Journal of Rheumatology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Flare Rate Thresholds for Patient Assessment of Disease Activity States in Gout
(Your Name) has forwarded a page to you from The Journal of Rheumatology
(Your Name) thought you would like to see this page from the The Journal of Rheumatology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Citation Tools
Flare Rate Thresholds for Patient Assessment of Disease Activity States in Gout
William Taylor, Nicola Dalbeth, Kenneth G. Saag, Jasvinder A. Singh, Elizabeth J. Rahn, Amy S. Mudano, Yi-Hsing Chen, Ching-Tsai Lin, Paul Tan, Worawit Louthreno, Janitzia Vazquez-Mellado, Hansel Hernández-Llinas, Tuhina Neogi, Ana B. Vargas-Santos, Geraldo Castelar-Pinheiro, Rodrigo B. Chaves-Amorim, Tillman Uhlig, Hilde B. Hammer, Maxim Eliseev, Fernando Perez-Ruiz, Lorenzo Cavagna, Geraldine M. McCarthy, Lisa K. Stamp, Martijin Gerritsen, Viktoria Fana, Francisca Sivera, Angelo L. Gaffo
The Journal of Rheumatology May 2020, jrheum.191242; DOI: 10.3899/jrheum.191242

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero

 Request Permissions

Share
Flare Rate Thresholds for Patient Assessment of Disease Activity States in Gout
William Taylor, Nicola Dalbeth, Kenneth G. Saag, Jasvinder A. Singh, Elizabeth J. Rahn, Amy S. Mudano, Yi-Hsing Chen, Ching-Tsai Lin, Paul Tan, Worawit Louthreno, Janitzia Vazquez-Mellado, Hansel Hernández-Llinas, Tuhina Neogi, Ana B. Vargas-Santos, Geraldo Castelar-Pinheiro, Rodrigo B. Chaves-Amorim, Tillman Uhlig, Hilde B. Hammer, Maxim Eliseev, Fernando Perez-Ruiz, Lorenzo Cavagna, Geraldine M. McCarthy, Lisa K. Stamp, Martijin Gerritsen, Viktoria Fana, Francisca Sivera, Angelo L. Gaffo
The Journal of Rheumatology May 2020, jrheum.191242; DOI: 10.3899/jrheum.191242
del.icio.us logo Digg logo Reddit logo Twitter logo CiteULike logo Facebook logo Google logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Bookmark this article

Jump to section

  • Article
  • Figures & Data
  • Supplemental
  • Info & Metrics
  • References
  • PDF
  • eLetters

Related Articles

Cited By...

More in this TOC Section

  • Comparative Effectiveness of BNT162b2 and mRNA-1273 Vaccines Against COVID-19 Infection Among Patients With Systemic Autoimmune Rheumatic Diseases on Immunomodulatory Medications
  • Clinimetric Validation of the Assessment of Spondyloarthritis International Society Health Index in Patients With Radiographic Axial Spondyloarthritis in Ixekizumab Trials
  • Sex-Specific Differences in Patients With Psoriatic Arthritis: A Systematic Review
Show more Articles

Similar Articles

Content

  • First Release
  • Current
  • Archives
  • Collections
  • Audiovisual Rheum
  • COVID-19 and Rheumatology

Resources

  • Guide for Authors
  • Submit Manuscript
  • Author Payment
  • Reviewers
  • Advertisers
  • Classified Ads
  • Reprints and Translations
  • Permissions
  • Meetings
  • FAQ
  • Policies

Subscribers

  • Subscription Information
  • Purchase Subscription
  • Your Account
  • Terms and Conditions

More

  • About Us
  • Contact Us
  • My Alerts
  • My Folders
  • Privacy/GDPR Policy
  • RSS Feeds
The Journal of Rheumatology
The content of this site is intended for health care professionals.
Copyright © 2022 by The Journal of Rheumatology Publishing Co. Ltd.
Print ISSN: 0315-162X; Online ISSN: 1499-2752
Powered by HighWire