Biologic Switching among Non-Systemic Juvenile Idiopathic Arthritis Patients: A Cohort Study in the Childhood Arthritis and Rheumatology Research Alliance Registry

Division of Pediatric Rheumatology, University of Alabama at Birmingham, Birmingham, AL, USA; Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, USA; Department of Pediatrics, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, USA; Rutgers Center for Pharmacoepidemiology and Treatment Science, Institute for Health, Health Care Policy and Aging Research, New Brunswick, NJ, USA; Department of Biostatistics and Epidemiology, Rutgers School of Public Health, Piscataway, NJ, USA; Division of Pediatric Rheumatology, Seattle Children’s Hospital, Seattle, WA, USA; Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA; Duke Clinical Research Institute, Duke University, Durham, NC, USA. Grants: This project was supported by funding from the Childhood Arthritis and Rheumatology Research Alliance. Address correspondence to Melissa L Mannion, 1600 7th Ave South, CPPN G10, Birmingham, AL 35233. E-mail: mmannion@peds.uab.edu

Division of Pediatric Rheumatology, University of Alabama at Birmingham, Birmingham, AL, USA; Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, USA; Department of Pediatrics, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, USA; Rutgers Center for Pharmacoepidemiology and Treatment Science, Institute for Health, Health Care Policy and Aging Research, New Brunswick, NJ, USA; Department of Biostatistics and Epidemiology, Rutgers School of Public Health, Piscataway, NJ, USA; Division of Pediatric Rheumatology, Seattle Children’s Hospital, Seattle, WA, USA; Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA; Duke Clinical Research Institute, Duke University, Durham, NC, USA. Grants: This project was supported by funding from the Childhood Arthritis and Rheumatology Research Alliance. Address correspondence to Melissa L Mannion, 1600 7th Ave South, CPPN G10, Birmingham, AL 35233. E-mail: mmannion@peds.uab.edu

Division of Pediatric Rheumatology, University of Alabama at Birmingham, Birmingham, AL, USA; Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, USA; Department of Pediatrics, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, USA; Rutgers Center for Pharmacoepidemiology and Treatment Science, Institute for Health, Health Care Policy and Aging Research, New Brunswick, NJ, USA; Department of Biostatistics and Epidemiology, Rutgers School of Public Health, Piscataway, NJ, USA; Division of Pediatric Rheumatology, Seattle Children’s Hospital, Seattle, WA, USA; Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA; Duke Clinical Research Institute, Duke University, Durham, NC, USA. Grants: This project was supported by funding from the Childhood Arthritis and Rheumatology Research Alliance. Address correspondence to Melissa L Mannion, 1600 7th Ave South, CPPN G10, Birmingham, AL 35233. E-mail: mmannion@peds.uab.edu

Division of Pediatric Rheumatology, University of Alabama at Birmingham, Birmingham, AL, USA; Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, USA; Department of Pediatrics, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, USA; Rutgers Center for Pharmacoepidemiology and Treatment Science, Institute for Health, Health Care Policy and Aging Research, New Brunswick, NJ, USA; Department of Biostatistics and Epidemiology, Rutgers School of Public Health, Piscataway, NJ, USA; Division of Pediatric Rheumatology, Seattle Children’s Hospital, Seattle, WA, USA; Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA; Duke Clinical Research Institute, Duke University, Durham, NC, USA. Grants: This project was supported by funding from the Childhood Arthritis and Rheumatology Research Alliance. Address correspondence to Melissa L Mannion, 1600 7th Ave South, CPPN G10, Birmingham, AL 35233. E-mail: mmannion@peds.uab.edu

Division of Pediatric Rheumatology, University of Alabama at Birmingham, Birmingham, AL, USA; Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, USA; Department of Pediatrics, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, USA; Rutgers Center for Pharmacoepidemiology and Treatment Science, Institute for Health, Health Care Policy and Aging Research, New Brunswick, NJ, USA; Department of Biostatistics and Epidemiology, Rutgers School of Public Health, Piscataway, NJ, USA; Division of Pediatric Rheumatology, Seattle Children’s Hospital, Seattle, WA, USA; Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA; Duke Clinical Research Institute, Duke University, Durham, NC, USA. Grants: This project was supported by funding from the Childhood Arthritis and Rheumatology Research Alliance. Address correspondence to Melissa L Mannion, 1600 7th Ave South, CPPN G10, Birmingham, AL 35233. E-mail: mmannion@peds.uab.edu

Division of Pediatric Rheumatology, University of Alabama at Birmingham, Birmingham, AL, USA; Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, USA; Department of Pediatrics, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, USA; Rutgers Center for Pharmacoepidemiology and Treatment Science, Institute for Health, Health Care Policy and Aging Research, New Brunswick, NJ, USA; Department of Biostatistics and Epidemiology, Rutgers School of Public Health, Piscataway, NJ, USA; Division of Pediatric Rheumatology, Seattle Children’s Hospital, Seattle, WA, USA; Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA; Duke Clinical Research Institute, Duke University, Durham, NC, USA. Grants: This project was supported by funding from the Childhood Arthritis and Rheumatology Research Alliance. Address correspondence to Melissa L Mannion, 1600 7th Ave South, CPPN G10, Birmingham, AL 35233. E-mail: mmannion@peds.uab.edu

Division of Pediatric Rheumatology, University of Alabama at Birmingham, Birmingham, AL, USA; Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, USA; Department of Pediatrics, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, USA; Rutgers Center for Pharmacoepidemiology and Treatment Science, Institute for Health, Health Care Policy and Aging Research, New Brunswick, NJ, USA; Department of Biostatistics and Epidemiology, Rutgers School of Public Health, Piscataway, NJ, USA; Division of Pediatric Rheumatology, Seattle Children’s Hospital, Seattle, WA, USA; Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA; Duke Clinical Research Institute, Duke University, Durham, NC, USA. Grants: This project was supported by funding from the Childhood Arthritis and Rheumatology Research Alliance. Address correspondence to Melissa L Mannion, 1600 7th Ave South, CPPN G10, Birmingham, AL 35233. E-mail: mmannion@peds.uab.edu