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Research ArticleAccepted Article

Prediction of work impact in axial spondylarthritis by the Work instability Scale, a prospective cohort study of 101 patients.

Irina Cucos, Sabrina Dadoun, Charlotte Jacquemin, Sarah Kreis, Stephanie Fabre, Christophe Hudry, Eduard Pertuiset, Bruno Fautrel and Laure Gossec
The Journal of Rheumatology September 2020, jrheum.191397; DOI: https://doi.org/10.3899/jrheum.191397
Irina Cucos
From the Rheumatology Department, Pitié-Salpêtrière Hospital, AP-HP, Paris, France. Address correspondence to Irina Cucos, Saint Mary Clincial Hospital, Rheumatology Department, 37-39, Ion Mihalache, Bucharest, 011172, Romania. Email: Irina.cucos@yahoo.com
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Sabrina Dadoun
From the Rheumatology Department, Pitié-Salpêtrière Hospital, AP-HP, Paris, France. Address correspondence to Irina Cucos, Saint Mary Clincial Hospital, Rheumatology Department, 37-39, Ion Mihalache, Bucharest, 011172, Romania. Email: Irina.cucos@yahoo.com
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Charlotte Jacquemin
From the Rheumatology Department, Pitié-Salpêtrière Hospital, AP-HP, Paris, France. Address correspondence to Irina Cucos, Saint Mary Clincial Hospital, Rheumatology Department, 37-39, Ion Mihalache, Bucharest, 011172, Romania. Email: Irina.cucos@yahoo.com
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Sarah Kreis
From the Rheumatology Department, Pitié-Salpêtrière Hospital, AP-HP, Paris, France. Address correspondence to Irina Cucos, Saint Mary Clincial Hospital, Rheumatology Department, 37-39, Ion Mihalache, Bucharest, 011172, Romania. Email: Irina.cucos@yahoo.com
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Stephanie Fabre
From the Rheumatology Department, Pitié-Salpêtrière Hospital, AP-HP, Paris, France. Address correspondence to Irina Cucos, Saint Mary Clincial Hospital, Rheumatology Department, 37-39, Ion Mihalache, Bucharest, 011172, Romania. Email: Irina.cucos@yahoo.com
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Christophe Hudry
From the Rheumatology Department, Pitié-Salpêtrière Hospital, AP-HP, Paris, France. Address correspondence to Irina Cucos, Saint Mary Clincial Hospital, Rheumatology Department, 37-39, Ion Mihalache, Bucharest, 011172, Romania. Email: Irina.cucos@yahoo.com
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Eduard Pertuiset
From the Rheumatology Department, Pitié-Salpêtrière Hospital, AP-HP, Paris, France. Address correspondence to Irina Cucos, Saint Mary Clincial Hospital, Rheumatology Department, 37-39, Ion Mihalache, Bucharest, 011172, Romania. Email: Irina.cucos@yahoo.com
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Bruno Fautrel
From the Rheumatology Department, Pitié-Salpêtrière Hospital, AP-HP, Paris, France. Address correspondence to Irina Cucos, Saint Mary Clincial Hospital, Rheumatology Department, 37-39, Ion Mihalache, Bucharest, 011172, Romania. Email: Irina.cucos@yahoo.com
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Laure Gossec
From the Rheumatology Department, Pitié-Salpêtrière Hospital, AP-HP, Paris, France. Address correspondence to Irina Cucos, Saint Mary Clincial Hospital, Rheumatology Department, 37-39, Ion Mihalache, Bucharest, 011172, Romania. Email: Irina.cucos@yahoo.com
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Abstract

Objective Axial spondyloarthritis (axSpA) may have an impact on work. The Ankylosing Spondylitis Work Instability Scale (AS-WIS) assesses difficulties at work. The objective of this study was to evaluate the predictive value of the AS WIS on work impact.

Methods Prospective cohort study with two timepoints (at baseline and after 1.5 years) including patients with axSpA and a paid professional activity. Patients completed the AS-WIS at baseline and work instability was scored as moderate/high if ≥11 (0-20 scale). At follow up, adverse work outcomes (AWO) were defined as short-term sick leave or severe AWO (long-term sick leave, disability, unemployment). Univariable and multivariable logistic regression analyses were performed to explain AWO.

Results Of 101 patients, mean age 45 (standard deviation (SD) 9) years, 52% male, disease duration was 14 (SD 8) years. The BASDAI and the BASFI were respectively 34 (SD 21) and 23 (SD 23), 69 (68%) received a TNF-inhibitor. At baseline, 46 (46%) patients had moderate/high AS-WIS. At 1.5 years of follow-up, 37 patients (36%) had AWO: 25 patients (25%) a short-term sick leave, and 12 patients (12%, 7/100 patient years) a severe AWO. Independent baseline factors associated with AWO were a moderate/high AS-WIS score (odds ratio 2.71 [95% confidence interval 1.04-7.22]) and shorter disease duration (0.94 [0.89-0.99]).

Conclusion In patients with axSpA, a moderate/high AS-WIS score was predictive of AWO in this population with well-controlled axSpA. This short questionnaire can be helpful to screen for future difficulties at work.

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The Journal of Rheumatology
Vol. 49, Issue 5
1 May 2022
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Accepted manuscript
Prediction of work impact in axial spondylarthritis by the Work instability Scale, a prospective cohort study of 101 patients.
Irina Cucos, Sabrina Dadoun, Charlotte Jacquemin, Sarah Kreis, Stephanie Fabre, Christophe Hudry, Eduard Pertuiset, Bruno Fautrel, Laure Gossec
The Journal of Rheumatology Sep 2020, jrheum.191397; DOI: 10.3899/jrheum.191397

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Accepted manuscript
Prediction of work impact in axial spondylarthritis by the Work instability Scale, a prospective cohort study of 101 patients.
Irina Cucos, Sabrina Dadoun, Charlotte Jacquemin, Sarah Kreis, Stephanie Fabre, Christophe Hudry, Eduard Pertuiset, Bruno Fautrel, Laure Gossec
The Journal of Rheumatology Sep 2020, jrheum.191397; DOI: 10.3899/jrheum.191397
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