Research ArticleArticle
Scope of Outcomes in Trials and Observational Studies of Interventions Targeting Medication Adherence in Rheumatic Conditions: A Systematic Review
Ayano Kelly, Luke Crimston-Smith, Allison Tong, Susan J. Bartlett, Charlotte L. Bekker, Robin Christensen, Mary A. De Vera, Maarten de Wit, Vicki Evans, Michael Gill, Lyn March, Karine Manera, Robby Nieuwlaat, Shahrzad Salmasi, Marieke Scholte-Voshaar, Jasvinder A. Singh, Daniel Sumpton, Karine Toupin-April, Peter Tugwell, Bart van den Bemt, Suzanne Verstappen and Kathleen Tymms
The Journal of Rheumatology December 2019, jrheum.190726; DOI: https://doi.org/10.3899/jrheum.190726
Ayano Kelly
From the College of Health and Medicine, Australian National University, Canberra, ACT; Canberra Rheumatology, Canberra, ACT; Centre for Kidney Research, The Children’s Hospital at Westmead, Sydney, NSW; Sydney School of Public Health, The University of Sydney, Sydney, NSW, Australia; Department of Medicine, McGill University and Research Institute, McGill University Health Centres, Montreal, Quebec, Canada; Division of Rheumatology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA; Department of Pharmacy, Radboud University Medical Centre, Nijmegen, the Netherlands; Musculoskeletal Statistics Unit, the Parker Institute, Copenhagen University Hospital, Copenhagen, Denmark; Research Unit of Rheumatology, Department of Clinical Research, University of Southern Denmark, Odense University Hospital, Odense, Denmark; Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver; Arthritis Research Canada, Richmond, British Columbia, Canada; OMERACT Patient Research Partner, the Netherlands; Clear Vision Consulting, and OMERACT Patient Research Partner, Canberra, ACT; Discipline of Optometry, University of Canberra, Canberra, ACT; Dragon Claw Website, and OMERACT Patient Research Partner, Sydney, NSW; Institute of Bone and Joint Research, Kolling Institute of Medical Research, Sydney, NSW; Department of Rheumatology, Royal North Shore Hospital, Sydney, NSW; Northern Clinical School, The University of Sydney, Sydney, NSW, Australia; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada; Department of Psychology, Health and Technology, University of Twente, Enschede, the Netherlands, and OMERACT Patient Research Partner; Medicine Service, VA Medical Center, Birmingham, Alabama; Department of Medicine, School of Medicine, and Division of Epidemiology, School of Public Health, University of Alabama, Birmingham, Alabama, USA; University of Alabama, Birmingham, Alabama, USA; Department of Rheumatology, Concord Hospital, Sydney, NSW, Australia; The Children’s Hospital of Eastern Ontario Research Institute, Ottawa; Department of Pediatrics and School of Rehabilitation Sciences, and Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada; Department of Pharmacy, Sint Maartenskliniek, Ubbergen, the Netherlands; Centre for Epidemiology Versus Arthritis, Centre for Musculoskeletal Research, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester; UK National Institute for Health Research (NIHR) Manchester Biomedical Research Centre, Manchester University Hospitals National Health Service (NHS) Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK; Department of Rheumatology, Canberra Hospital, Canberra, ACT, Australia. The work reported in this manuscript was supported by the 2018 Arthritis Australia Project Grant. AK is supported by the Australian Government Research Training Scholarship. SV is supported by Versus Arthritis (grant number 20385) and NIHR Manchester Biomedical Research Centre. RC (The Parker Institute, Copenhagen University Hospital) is supported by a core grant from the Oak Foundation (OCAY-13-309). The funders had no role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript. A. Kelly, MBBS, FRACP, College of Health and Medicine, Australian National University, and Canberra Rheumatology, and Centre for Kidney Research, The Children’s Hospital at Westmead; L. Crimston-Smith, BN, College of Health and Medicine, Australian National University, and Canberra Rheumatology; A. Tong, PhD, Professor, Centre for Kidney Research, The Children’s Hospital at Westmead, and Sydney School of Public Health, The University of Sydney; S.J. Bartlett, PhD, Professor, Department of Medicine, McGill University and Research Institute, McGill University Health Centres, and Division of Rheumatology, Johns Hopkins School of Medicine; C.L. Bekker, PhD, Department of Pharmacy, Radboud University Medical Centre; R. Christensen, Musculoskeletal Statistics Unit, the Parker Institute, Copenhagen University Hospital, and the Research Unit of Rheumatology, Department of Clinical Research, University of Southern Denmark, Odense University Hospital; M.A. De Vera, PhD, Assistant Professor, Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, The University of British Columbia, and Arthritis Research Canada; M. de Wit, PhD, OMERACT Patient Research Partner; V. Evans, PhD, Clear Vision Consulting, and OMERACT Patient Research Partner, and Discipline of Optometry, University of Canberra; M. Gill, BA, Dragon Claw Website, and OMERACT Patient Research Partner; L. March, PhD, Professor, Institute of Bone and Joint Research, Kolling Institute of Medical Research, and the Department of Rheumatology, Royal North Shore Hospital, and the Northern Clinical School, The University of Sydney; K. Manera, MIPH, Centre for Kidney Research, The Children’s Hospital at Westmead, and the Sydney School of Public Health, The University of Sydney; R. Nieuwlaat, PhD, Associate Professor, Department of Health Research Methods, Evidence, and Impact, McMaster University; S. Salmasi, MSc, Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, University of British Columbia, and Arthritis Research Canada; M. Scholte-Voshaar, MSc, Department of Psychology, Health and Technology, University of Twente, and OMERACT Patient Research Partner; J.A. Singh, MD, Professor, Medicine Service, VA Medical Center, and Department of Medicine, School of Medicine, and Division of Epidemiology, School of Public Health, University of Alabama; D. Sumpton, MBBS, FRACP, Centre for Kidney Research, The Children’s Hospital at Westmead, Sydney, and Sydney School of Public Health, The University of Sydney, and Department of Rheumatology, Concord Hospital; K. Toupin-April, PhD, Associate Scientist, The Children’s Hospital of Eastern Ontario Research Institute, and Assistant Professor, the Department of Pediatrics and School of Rehabilitation Sciences, University of Ottawa; P. Tugwell, MD, Professor, Department of Medicine, University of Ottawa; B. van den Bemt, PhD, Assistant Professor, Department of Pharmacy, Radboud University Medical Centre, and Department of Pharmacy, Sint Maartenskliniek; S. Verstappen, PhD, Reader, Centre for Epidemiology Versus Arthritis, Centre for Musculoskeletal Research, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, and NIHR Manchester Biomedical Research Centre, Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre; K. Tymms, MBBS, FRACP, Associate Professor, College of Health and Medicine, Australian National University, and Canberra Rheumatology, and Department of Rheumatology, Canberra Hospital. Address correspondence to A. Kelly, 40 Marcus Clarke St., Canberra City, ACT 2601, Australia. Email: ayano.kelly@anu.edu.au. Accepted for publication December 6, 2019.
Luke Crimston-Smith
From the College of Health and Medicine, Australian National University, Canberra, ACT; Canberra Rheumatology, Canberra, ACT; Centre for Kidney Research, The Children’s Hospital at Westmead, Sydney, NSW; Sydney School of Public Health, The University of Sydney, Sydney, NSW, Australia; Department of Medicine, McGill University and Research Institute, McGill University Health Centres, Montreal, Quebec, Canada; Division of Rheumatology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA; Department of Pharmacy, Radboud University Medical Centre, Nijmegen, the Netherlands; Musculoskeletal Statistics Unit, the Parker Institute, Copenhagen University Hospital, Copenhagen, Denmark; Research Unit of Rheumatology, Department of Clinical Research, University of Southern Denmark, Odense University Hospital, Odense, Denmark; Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver; Arthritis Research Canada, Richmond, British Columbia, Canada; OMERACT Patient Research Partner, the Netherlands; Clear Vision Consulting, and OMERACT Patient Research Partner, Canberra, ACT; Discipline of Optometry, University of Canberra, Canberra, ACT; Dragon Claw Website, and OMERACT Patient Research Partner, Sydney, NSW; Institute of Bone and Joint Research, Kolling Institute of Medical Research, Sydney, NSW; Department of Rheumatology, Royal North Shore Hospital, Sydney, NSW; Northern Clinical School, The University of Sydney, Sydney, NSW, Australia; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada; Department of Psychology, Health and Technology, University of Twente, Enschede, the Netherlands, and OMERACT Patient Research Partner; Medicine Service, VA Medical Center, Birmingham, Alabama; Department of Medicine, School of Medicine, and Division of Epidemiology, School of Public Health, University of Alabama, Birmingham, Alabama, USA; University of Alabama, Birmingham, Alabama, USA; Department of Rheumatology, Concord Hospital, Sydney, NSW, Australia; The Children’s Hospital of Eastern Ontario Research Institute, Ottawa; Department of Pediatrics and School of Rehabilitation Sciences, and Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada; Department of Pharmacy, Sint Maartenskliniek, Ubbergen, the Netherlands; Centre for Epidemiology Versus Arthritis, Centre for Musculoskeletal Research, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester; UK National Institute for Health Research (NIHR) Manchester Biomedical Research Centre, Manchester University Hospitals National Health Service (NHS) Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK; Department of Rheumatology, Canberra Hospital, Canberra, ACT, Australia. The work reported in this manuscript was supported by the 2018 Arthritis Australia Project Grant. AK is supported by the Australian Government Research Training Scholarship. SV is supported by Versus Arthritis (grant number 20385) and NIHR Manchester Biomedical Research Centre. RC (The Parker Institute, Copenhagen University Hospital) is supported by a core grant from the Oak Foundation (OCAY-13-309). The funders had no role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript. A. Kelly, MBBS, FRACP, College of Health and Medicine, Australian National University, and Canberra Rheumatology, and Centre for Kidney Research, The Children’s Hospital at Westmead; L. Crimston-Smith, BN, College of Health and Medicine, Australian National University, and Canberra Rheumatology; A. Tong, PhD, Professor, Centre for Kidney Research, The Children’s Hospital at Westmead, and Sydney School of Public Health, The University of Sydney; S.J. Bartlett, PhD, Professor, Department of Medicine, McGill University and Research Institute, McGill University Health Centres, and Division of Rheumatology, Johns Hopkins School of Medicine; C.L. Bekker, PhD, Department of Pharmacy, Radboud University Medical Centre; R. Christensen, Musculoskeletal Statistics Unit, the Parker Institute, Copenhagen University Hospital, and the Research Unit of Rheumatology, Department of Clinical Research, University of Southern Denmark, Odense University Hospital; M.A. De Vera, PhD, Assistant Professor, Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, The University of British Columbia, and Arthritis Research Canada; M. de Wit, PhD, OMERACT Patient Research Partner; V. Evans, PhD, Clear Vision Consulting, and OMERACT Patient Research Partner, and Discipline of Optometry, University of Canberra; M. Gill, BA, Dragon Claw Website, and OMERACT Patient Research Partner; L. March, PhD, Professor, Institute of Bone and Joint Research, Kolling Institute of Medical Research, and the Department of Rheumatology, Royal North Shore Hospital, and the Northern Clinical School, The University of Sydney; K. Manera, MIPH, Centre for Kidney Research, The Children’s Hospital at Westmead, and the Sydney School of Public Health, The University of Sydney; R. Nieuwlaat, PhD, Associate Professor, Department of Health Research Methods, Evidence, and Impact, McMaster University; S. Salmasi, MSc, Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, University of British Columbia, and Arthritis Research Canada; M. Scholte-Voshaar, MSc, Department of Psychology, Health and Technology, University of Twente, and OMERACT Patient Research Partner; J.A. Singh, MD, Professor, Medicine Service, VA Medical Center, and Department of Medicine, School of Medicine, and Division of Epidemiology, School of Public Health, University of Alabama; D. Sumpton, MBBS, FRACP, Centre for Kidney Research, The Children’s Hospital at Westmead, Sydney, and Sydney School of Public Health, The University of Sydney, and Department of Rheumatology, Concord Hospital; K. Toupin-April, PhD, Associate Scientist, The Children’s Hospital of Eastern Ontario Research Institute, and Assistant Professor, the Department of Pediatrics and School of Rehabilitation Sciences, University of Ottawa; P. Tugwell, MD, Professor, Department of Medicine, University of Ottawa; B. van den Bemt, PhD, Assistant Professor, Department of Pharmacy, Radboud University Medical Centre, and Department of Pharmacy, Sint Maartenskliniek; S. Verstappen, PhD, Reader, Centre for Epidemiology Versus Arthritis, Centre for Musculoskeletal Research, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, and NIHR Manchester Biomedical Research Centre, Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre; K. Tymms, MBBS, FRACP, Associate Professor, College of Health and Medicine, Australian National University, and Canberra Rheumatology, and Department of Rheumatology, Canberra Hospital. Address correspondence to A. Kelly, 40 Marcus Clarke St., Canberra City, ACT 2601, Australia. Email: ayano.kelly@anu.edu.au. Accepted for publication December 6, 2019.
Allison Tong
From the College of Health and Medicine, Australian National University, Canberra, ACT; Canberra Rheumatology, Canberra, ACT; Centre for Kidney Research, The Children’s Hospital at Westmead, Sydney, NSW; Sydney School of Public Health, The University of Sydney, Sydney, NSW, Australia; Department of Medicine, McGill University and Research Institute, McGill University Health Centres, Montreal, Quebec, Canada; Division of Rheumatology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA; Department of Pharmacy, Radboud University Medical Centre, Nijmegen, the Netherlands; Musculoskeletal Statistics Unit, the Parker Institute, Copenhagen University Hospital, Copenhagen, Denmark; Research Unit of Rheumatology, Department of Clinical Research, University of Southern Denmark, Odense University Hospital, Odense, Denmark; Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver; Arthritis Research Canada, Richmond, British Columbia, Canada; OMERACT Patient Research Partner, the Netherlands; Clear Vision Consulting, and OMERACT Patient Research Partner, Canberra, ACT; Discipline of Optometry, University of Canberra, Canberra, ACT; Dragon Claw Website, and OMERACT Patient Research Partner, Sydney, NSW; Institute of Bone and Joint Research, Kolling Institute of Medical Research, Sydney, NSW; Department of Rheumatology, Royal North Shore Hospital, Sydney, NSW; Northern Clinical School, The University of Sydney, Sydney, NSW, Australia; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada; Department of Psychology, Health and Technology, University of Twente, Enschede, the Netherlands, and OMERACT Patient Research Partner; Medicine Service, VA Medical Center, Birmingham, Alabama; Department of Medicine, School of Medicine, and Division of Epidemiology, School of Public Health, University of Alabama, Birmingham, Alabama, USA; University of Alabama, Birmingham, Alabama, USA; Department of Rheumatology, Concord Hospital, Sydney, NSW, Australia; The Children’s Hospital of Eastern Ontario Research Institute, Ottawa; Department of Pediatrics and School of Rehabilitation Sciences, and Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada; Department of Pharmacy, Sint Maartenskliniek, Ubbergen, the Netherlands; Centre for Epidemiology Versus Arthritis, Centre for Musculoskeletal Research, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester; UK National Institute for Health Research (NIHR) Manchester Biomedical Research Centre, Manchester University Hospitals National Health Service (NHS) Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK; Department of Rheumatology, Canberra Hospital, Canberra, ACT, Australia. The work reported in this manuscript was supported by the 2018 Arthritis Australia Project Grant. AK is supported by the Australian Government Research Training Scholarship. SV is supported by Versus Arthritis (grant number 20385) and NIHR Manchester Biomedical Research Centre. RC (The Parker Institute, Copenhagen University Hospital) is supported by a core grant from the Oak Foundation (OCAY-13-309). The funders had no role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript. A. Kelly, MBBS, FRACP, College of Health and Medicine, Australian National University, and Canberra Rheumatology, and Centre for Kidney Research, The Children’s Hospital at Westmead; L. Crimston-Smith, BN, College of Health and Medicine, Australian National University, and Canberra Rheumatology; A. Tong, PhD, Professor, Centre for Kidney Research, The Children’s Hospital at Westmead, and Sydney School of Public Health, The University of Sydney; S.J. Bartlett, PhD, Professor, Department of Medicine, McGill University and Research Institute, McGill University Health Centres, and Division of Rheumatology, Johns Hopkins School of Medicine; C.L. Bekker, PhD, Department of Pharmacy, Radboud University Medical Centre; R. Christensen, Musculoskeletal Statistics Unit, the Parker Institute, Copenhagen University Hospital, and the Research Unit of Rheumatology, Department of Clinical Research, University of Southern Denmark, Odense University Hospital; M.A. De Vera, PhD, Assistant Professor, Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, The University of British Columbia, and Arthritis Research Canada; M. de Wit, PhD, OMERACT Patient Research Partner; V. Evans, PhD, Clear Vision Consulting, and OMERACT Patient Research Partner, and Discipline of Optometry, University of Canberra; M. Gill, BA, Dragon Claw Website, and OMERACT Patient Research Partner; L. March, PhD, Professor, Institute of Bone and Joint Research, Kolling Institute of Medical Research, and the Department of Rheumatology, Royal North Shore Hospital, and the Northern Clinical School, The University of Sydney; K. Manera, MIPH, Centre for Kidney Research, The Children’s Hospital at Westmead, and the Sydney School of Public Health, The University of Sydney; R. Nieuwlaat, PhD, Associate Professor, Department of Health Research Methods, Evidence, and Impact, McMaster University; S. Salmasi, MSc, Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, University of British Columbia, and Arthritis Research Canada; M. Scholte-Voshaar, MSc, Department of Psychology, Health and Technology, University of Twente, and OMERACT Patient Research Partner; J.A. Singh, MD, Professor, Medicine Service, VA Medical Center, and Department of Medicine, School of Medicine, and Division of Epidemiology, School of Public Health, University of Alabama; D. Sumpton, MBBS, FRACP, Centre for Kidney Research, The Children’s Hospital at Westmead, Sydney, and Sydney School of Public Health, The University of Sydney, and Department of Rheumatology, Concord Hospital; K. Toupin-April, PhD, Associate Scientist, The Children’s Hospital of Eastern Ontario Research Institute, and Assistant Professor, the Department of Pediatrics and School of Rehabilitation Sciences, University of Ottawa; P. Tugwell, MD, Professor, Department of Medicine, University of Ottawa; B. van den Bemt, PhD, Assistant Professor, Department of Pharmacy, Radboud University Medical Centre, and Department of Pharmacy, Sint Maartenskliniek; S. Verstappen, PhD, Reader, Centre for Epidemiology Versus Arthritis, Centre for Musculoskeletal Research, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, and NIHR Manchester Biomedical Research Centre, Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre; K. Tymms, MBBS, FRACP, Associate Professor, College of Health and Medicine, Australian National University, and Canberra Rheumatology, and Department of Rheumatology, Canberra Hospital. Address correspondence to A. Kelly, 40 Marcus Clarke St., Canberra City, ACT 2601, Australia. Email: ayano.kelly@anu.edu.au. Accepted for publication December 6, 2019.
Susan J. Bartlett
From the College of Health and Medicine, Australian National University, Canberra, ACT; Canberra Rheumatology, Canberra, ACT; Centre for Kidney Research, The Children’s Hospital at Westmead, Sydney, NSW; Sydney School of Public Health, The University of Sydney, Sydney, NSW, Australia; Department of Medicine, McGill University and Research Institute, McGill University Health Centres, Montreal, Quebec, Canada; Division of Rheumatology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA; Department of Pharmacy, Radboud University Medical Centre, Nijmegen, the Netherlands; Musculoskeletal Statistics Unit, the Parker Institute, Copenhagen University Hospital, Copenhagen, Denmark; Research Unit of Rheumatology, Department of Clinical Research, University of Southern Denmark, Odense University Hospital, Odense, Denmark; Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver; Arthritis Research Canada, Richmond, British Columbia, Canada; OMERACT Patient Research Partner, the Netherlands; Clear Vision Consulting, and OMERACT Patient Research Partner, Canberra, ACT; Discipline of Optometry, University of Canberra, Canberra, ACT; Dragon Claw Website, and OMERACT Patient Research Partner, Sydney, NSW; Institute of Bone and Joint Research, Kolling Institute of Medical Research, Sydney, NSW; Department of Rheumatology, Royal North Shore Hospital, Sydney, NSW; Northern Clinical School, The University of Sydney, Sydney, NSW, Australia; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada; Department of Psychology, Health and Technology, University of Twente, Enschede, the Netherlands, and OMERACT Patient Research Partner; Medicine Service, VA Medical Center, Birmingham, Alabama; Department of Medicine, School of Medicine, and Division of Epidemiology, School of Public Health, University of Alabama, Birmingham, Alabama, USA; University of Alabama, Birmingham, Alabama, USA; Department of Rheumatology, Concord Hospital, Sydney, NSW, Australia; The Children’s Hospital of Eastern Ontario Research Institute, Ottawa; Department of Pediatrics and School of Rehabilitation Sciences, and Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada; Department of Pharmacy, Sint Maartenskliniek, Ubbergen, the Netherlands; Centre for Epidemiology Versus Arthritis, Centre for Musculoskeletal Research, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester; UK National Institute for Health Research (NIHR) Manchester Biomedical Research Centre, Manchester University Hospitals National Health Service (NHS) Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK; Department of Rheumatology, Canberra Hospital, Canberra, ACT, Australia. The work reported in this manuscript was supported by the 2018 Arthritis Australia Project Grant. AK is supported by the Australian Government Research Training Scholarship. SV is supported by Versus Arthritis (grant number 20385) and NIHR Manchester Biomedical Research Centre. RC (The Parker Institute, Copenhagen University Hospital) is supported by a core grant from the Oak Foundation (OCAY-13-309). The funders had no role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript. A. Kelly, MBBS, FRACP, College of Health and Medicine, Australian National University, and Canberra Rheumatology, and Centre for Kidney Research, The Children’s Hospital at Westmead; L. Crimston-Smith, BN, College of Health and Medicine, Australian National University, and Canberra Rheumatology; A. Tong, PhD, Professor, Centre for Kidney Research, The Children’s Hospital at Westmead, and Sydney School of Public Health, The University of Sydney; S.J. Bartlett, PhD, Professor, Department of Medicine, McGill University and Research Institute, McGill University Health Centres, and Division of Rheumatology, Johns Hopkins School of Medicine; C.L. Bekker, PhD, Department of Pharmacy, Radboud University Medical Centre; R. Christensen, Musculoskeletal Statistics Unit, the Parker Institute, Copenhagen University Hospital, and the Research Unit of Rheumatology, Department of Clinical Research, University of Southern Denmark, Odense University Hospital; M.A. De Vera, PhD, Assistant Professor, Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, The University of British Columbia, and Arthritis Research Canada; M. de Wit, PhD, OMERACT Patient Research Partner; V. Evans, PhD, Clear Vision Consulting, and OMERACT Patient Research Partner, and Discipline of Optometry, University of Canberra; M. Gill, BA, Dragon Claw Website, and OMERACT Patient Research Partner; L. March, PhD, Professor, Institute of Bone and Joint Research, Kolling Institute of Medical Research, and the Department of Rheumatology, Royal North Shore Hospital, and the Northern Clinical School, The University of Sydney; K. Manera, MIPH, Centre for Kidney Research, The Children’s Hospital at Westmead, and the Sydney School of Public Health, The University of Sydney; R. Nieuwlaat, PhD, Associate Professor, Department of Health Research Methods, Evidence, and Impact, McMaster University; S. Salmasi, MSc, Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, University of British Columbia, and Arthritis Research Canada; M. Scholte-Voshaar, MSc, Department of Psychology, Health and Technology, University of Twente, and OMERACT Patient Research Partner; J.A. Singh, MD, Professor, Medicine Service, VA Medical Center, and Department of Medicine, School of Medicine, and Division of Epidemiology, School of Public Health, University of Alabama; D. Sumpton, MBBS, FRACP, Centre for Kidney Research, The Children’s Hospital at Westmead, Sydney, and Sydney School of Public Health, The University of Sydney, and Department of Rheumatology, Concord Hospital; K. Toupin-April, PhD, Associate Scientist, The Children’s Hospital of Eastern Ontario Research Institute, and Assistant Professor, the Department of Pediatrics and School of Rehabilitation Sciences, University of Ottawa; P. Tugwell, MD, Professor, Department of Medicine, University of Ottawa; B. van den Bemt, PhD, Assistant Professor, Department of Pharmacy, Radboud University Medical Centre, and Department of Pharmacy, Sint Maartenskliniek; S. Verstappen, PhD, Reader, Centre for Epidemiology Versus Arthritis, Centre for Musculoskeletal Research, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, and NIHR Manchester Biomedical Research Centre, Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre; K. Tymms, MBBS, FRACP, Associate Professor, College of Health and Medicine, Australian National University, and Canberra Rheumatology, and Department of Rheumatology, Canberra Hospital. Address correspondence to A. Kelly, 40 Marcus Clarke St., Canberra City, ACT 2601, Australia. Email: ayano.kelly@anu.edu.au. Accepted for publication December 6, 2019.
Charlotte L. Bekker
From the College of Health and Medicine, Australian National University, Canberra, ACT; Canberra Rheumatology, Canberra, ACT; Centre for Kidney Research, The Children’s Hospital at Westmead, Sydney, NSW; Sydney School of Public Health, The University of Sydney, Sydney, NSW, Australia; Department of Medicine, McGill University and Research Institute, McGill University Health Centres, Montreal, Quebec, Canada; Division of Rheumatology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA; Department of Pharmacy, Radboud University Medical Centre, Nijmegen, the Netherlands; Musculoskeletal Statistics Unit, the Parker Institute, Copenhagen University Hospital, Copenhagen, Denmark; Research Unit of Rheumatology, Department of Clinical Research, University of Southern Denmark, Odense University Hospital, Odense, Denmark; Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver; Arthritis Research Canada, Richmond, British Columbia, Canada; OMERACT Patient Research Partner, the Netherlands; Clear Vision Consulting, and OMERACT Patient Research Partner, Canberra, ACT; Discipline of Optometry, University of Canberra, Canberra, ACT; Dragon Claw Website, and OMERACT Patient Research Partner, Sydney, NSW; Institute of Bone and Joint Research, Kolling Institute of Medical Research, Sydney, NSW; Department of Rheumatology, Royal North Shore Hospital, Sydney, NSW; Northern Clinical School, The University of Sydney, Sydney, NSW, Australia; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada; Department of Psychology, Health and Technology, University of Twente, Enschede, the Netherlands, and OMERACT Patient Research Partner; Medicine Service, VA Medical Center, Birmingham, Alabama; Department of Medicine, School of Medicine, and Division of Epidemiology, School of Public Health, University of Alabama, Birmingham, Alabama, USA; University of Alabama, Birmingham, Alabama, USA; Department of Rheumatology, Concord Hospital, Sydney, NSW, Australia; The Children’s Hospital of Eastern Ontario Research Institute, Ottawa; Department of Pediatrics and School of Rehabilitation Sciences, and Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada; Department of Pharmacy, Sint Maartenskliniek, Ubbergen, the Netherlands; Centre for Epidemiology Versus Arthritis, Centre for Musculoskeletal Research, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester; UK National Institute for Health Research (NIHR) Manchester Biomedical Research Centre, Manchester University Hospitals National Health Service (NHS) Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK; Department of Rheumatology, Canberra Hospital, Canberra, ACT, Australia. The work reported in this manuscript was supported by the 2018 Arthritis Australia Project Grant. AK is supported by the Australian Government Research Training Scholarship. SV is supported by Versus Arthritis (grant number 20385) and NIHR Manchester Biomedical Research Centre. RC (The Parker Institute, Copenhagen University Hospital) is supported by a core grant from the Oak Foundation (OCAY-13-309). The funders had no role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript. A. Kelly, MBBS, FRACP, College of Health and Medicine, Australian National University, and Canberra Rheumatology, and Centre for Kidney Research, The Children’s Hospital at Westmead; L. Crimston-Smith, BN, College of Health and Medicine, Australian National University, and Canberra Rheumatology; A. Tong, PhD, Professor, Centre for Kidney Research, The Children’s Hospital at Westmead, and Sydney School of Public Health, The University of Sydney; S.J. Bartlett, PhD, Professor, Department of Medicine, McGill University and Research Institute, McGill University Health Centres, and Division of Rheumatology, Johns Hopkins School of Medicine; C.L. Bekker, PhD, Department of Pharmacy, Radboud University Medical Centre; R. Christensen, Musculoskeletal Statistics Unit, the Parker Institute, Copenhagen University Hospital, and the Research Unit of Rheumatology, Department of Clinical Research, University of Southern Denmark, Odense University Hospital; M.A. De Vera, PhD, Assistant Professor, Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, The University of British Columbia, and Arthritis Research Canada; M. de Wit, PhD, OMERACT Patient Research Partner; V. Evans, PhD, Clear Vision Consulting, and OMERACT Patient Research Partner, and Discipline of Optometry, University of Canberra; M. Gill, BA, Dragon Claw Website, and OMERACT Patient Research Partner; L. March, PhD, Professor, Institute of Bone and Joint Research, Kolling Institute of Medical Research, and the Department of Rheumatology, Royal North Shore Hospital, and the Northern Clinical School, The University of Sydney; K. Manera, MIPH, Centre for Kidney Research, The Children’s Hospital at Westmead, and the Sydney School of Public Health, The University of Sydney; R. Nieuwlaat, PhD, Associate Professor, Department of Health Research Methods, Evidence, and Impact, McMaster University; S. Salmasi, MSc, Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, University of British Columbia, and Arthritis Research Canada; M. Scholte-Voshaar, MSc, Department of Psychology, Health and Technology, University of Twente, and OMERACT Patient Research Partner; J.A. Singh, MD, Professor, Medicine Service, VA Medical Center, and Department of Medicine, School of Medicine, and Division of Epidemiology, School of Public Health, University of Alabama; D. Sumpton, MBBS, FRACP, Centre for Kidney Research, The Children’s Hospital at Westmead, Sydney, and Sydney School of Public Health, The University of Sydney, and Department of Rheumatology, Concord Hospital; K. Toupin-April, PhD, Associate Scientist, The Children’s Hospital of Eastern Ontario Research Institute, and Assistant Professor, the Department of Pediatrics and School of Rehabilitation Sciences, University of Ottawa; P. Tugwell, MD, Professor, Department of Medicine, University of Ottawa; B. van den Bemt, PhD, Assistant Professor, Department of Pharmacy, Radboud University Medical Centre, and Department of Pharmacy, Sint Maartenskliniek; S. Verstappen, PhD, Reader, Centre for Epidemiology Versus Arthritis, Centre for Musculoskeletal Research, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, and NIHR Manchester Biomedical Research Centre, Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre; K. Tymms, MBBS, FRACP, Associate Professor, College of Health and Medicine, Australian National University, and Canberra Rheumatology, and Department of Rheumatology, Canberra Hospital. Address correspondence to A. Kelly, 40 Marcus Clarke St., Canberra City, ACT 2601, Australia. Email: ayano.kelly@anu.edu.au. Accepted for publication December 6, 2019.
Robin Christensen
From the College of Health and Medicine, Australian National University, Canberra, ACT; Canberra Rheumatology, Canberra, ACT; Centre for Kidney Research, The Children’s Hospital at Westmead, Sydney, NSW; Sydney School of Public Health, The University of Sydney, Sydney, NSW, Australia; Department of Medicine, McGill University and Research Institute, McGill University Health Centres, Montreal, Quebec, Canada; Division of Rheumatology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA; Department of Pharmacy, Radboud University Medical Centre, Nijmegen, the Netherlands; Musculoskeletal Statistics Unit, the Parker Institute, Copenhagen University Hospital, Copenhagen, Denmark; Research Unit of Rheumatology, Department of Clinical Research, University of Southern Denmark, Odense University Hospital, Odense, Denmark; Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver; Arthritis Research Canada, Richmond, British Columbia, Canada; OMERACT Patient Research Partner, the Netherlands; Clear Vision Consulting, and OMERACT Patient Research Partner, Canberra, ACT; Discipline of Optometry, University of Canberra, Canberra, ACT; Dragon Claw Website, and OMERACT Patient Research Partner, Sydney, NSW; Institute of Bone and Joint Research, Kolling Institute of Medical Research, Sydney, NSW; Department of Rheumatology, Royal North Shore Hospital, Sydney, NSW; Northern Clinical School, The University of Sydney, Sydney, NSW, Australia; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada; Department of Psychology, Health and Technology, University of Twente, Enschede, the Netherlands, and OMERACT Patient Research Partner; Medicine Service, VA Medical Center, Birmingham, Alabama; Department of Medicine, School of Medicine, and Division of Epidemiology, School of Public Health, University of Alabama, Birmingham, Alabama, USA; University of Alabama, Birmingham, Alabama, USA; Department of Rheumatology, Concord Hospital, Sydney, NSW, Australia; The Children’s Hospital of Eastern Ontario Research Institute, Ottawa; Department of Pediatrics and School of Rehabilitation Sciences, and Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada; Department of Pharmacy, Sint Maartenskliniek, Ubbergen, the Netherlands; Centre for Epidemiology Versus Arthritis, Centre for Musculoskeletal Research, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester; UK National Institute for Health Research (NIHR) Manchester Biomedical Research Centre, Manchester University Hospitals National Health Service (NHS) Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK; Department of Rheumatology, Canberra Hospital, Canberra, ACT, Australia. The work reported in this manuscript was supported by the 2018 Arthritis Australia Project Grant. AK is supported by the Australian Government Research Training Scholarship. SV is supported by Versus Arthritis (grant number 20385) and NIHR Manchester Biomedical Research Centre. RC (The Parker Institute, Copenhagen University Hospital) is supported by a core grant from the Oak Foundation (OCAY-13-309). The funders had no role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript. A. Kelly, MBBS, FRACP, College of Health and Medicine, Australian National University, and Canberra Rheumatology, and Centre for Kidney Research, The Children’s Hospital at Westmead; L. Crimston-Smith, BN, College of Health and Medicine, Australian National University, and Canberra Rheumatology; A. Tong, PhD, Professor, Centre for Kidney Research, The Children’s Hospital at Westmead, and Sydney School of Public Health, The University of Sydney; S.J. Bartlett, PhD, Professor, Department of Medicine, McGill University and Research Institute, McGill University Health Centres, and Division of Rheumatology, Johns Hopkins School of Medicine; C.L. Bekker, PhD, Department of Pharmacy, Radboud University Medical Centre; R. Christensen, Musculoskeletal Statistics Unit, the Parker Institute, Copenhagen University Hospital, and the Research Unit of Rheumatology, Department of Clinical Research, University of Southern Denmark, Odense University Hospital; M.A. De Vera, PhD, Assistant Professor, Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, The University of British Columbia, and Arthritis Research Canada; M. de Wit, PhD, OMERACT Patient Research Partner; V. Evans, PhD, Clear Vision Consulting, and OMERACT Patient Research Partner, and Discipline of Optometry, University of Canberra; M. Gill, BA, Dragon Claw Website, and OMERACT Patient Research Partner; L. March, PhD, Professor, Institute of Bone and Joint Research, Kolling Institute of Medical Research, and the Department of Rheumatology, Royal North Shore Hospital, and the Northern Clinical School, The University of Sydney; K. Manera, MIPH, Centre for Kidney Research, The Children’s Hospital at Westmead, and the Sydney School of Public Health, The University of Sydney; R. Nieuwlaat, PhD, Associate Professor, Department of Health Research Methods, Evidence, and Impact, McMaster University; S. Salmasi, MSc, Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, University of British Columbia, and Arthritis Research Canada; M. Scholte-Voshaar, MSc, Department of Psychology, Health and Technology, University of Twente, and OMERACT Patient Research Partner; J.A. Singh, MD, Professor, Medicine Service, VA Medical Center, and Department of Medicine, School of Medicine, and Division of Epidemiology, School of Public Health, University of Alabama; D. Sumpton, MBBS, FRACP, Centre for Kidney Research, The Children’s Hospital at Westmead, Sydney, and Sydney School of Public Health, The University of Sydney, and Department of Rheumatology, Concord Hospital; K. Toupin-April, PhD, Associate Scientist, The Children’s Hospital of Eastern Ontario Research Institute, and Assistant Professor, the Department of Pediatrics and School of Rehabilitation Sciences, University of Ottawa; P. Tugwell, MD, Professor, Department of Medicine, University of Ottawa; B. van den Bemt, PhD, Assistant Professor, Department of Pharmacy, Radboud University Medical Centre, and Department of Pharmacy, Sint Maartenskliniek; S. Verstappen, PhD, Reader, Centre for Epidemiology Versus Arthritis, Centre for Musculoskeletal Research, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, and NIHR Manchester Biomedical Research Centre, Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre; K. Tymms, MBBS, FRACP, Associate Professor, College of Health and Medicine, Australian National University, and Canberra Rheumatology, and Department of Rheumatology, Canberra Hospital. Address correspondence to A. Kelly, 40 Marcus Clarke St., Canberra City, ACT 2601, Australia. Email: ayano.kelly@anu.edu.au. Accepted for publication December 6, 2019.
Mary A. De Vera
From the College of Health and Medicine, Australian National University, Canberra, ACT; Canberra Rheumatology, Canberra, ACT; Centre for Kidney Research, The Children’s Hospital at Westmead, Sydney, NSW; Sydney School of Public Health, The University of Sydney, Sydney, NSW, Australia; Department of Medicine, McGill University and Research Institute, McGill University Health Centres, Montreal, Quebec, Canada; Division of Rheumatology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA; Department of Pharmacy, Radboud University Medical Centre, Nijmegen, the Netherlands; Musculoskeletal Statistics Unit, the Parker Institute, Copenhagen University Hospital, Copenhagen, Denmark; Research Unit of Rheumatology, Department of Clinical Research, University of Southern Denmark, Odense University Hospital, Odense, Denmark; Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver; Arthritis Research Canada, Richmond, British Columbia, Canada; OMERACT Patient Research Partner, the Netherlands; Clear Vision Consulting, and OMERACT Patient Research Partner, Canberra, ACT; Discipline of Optometry, University of Canberra, Canberra, ACT; Dragon Claw Website, and OMERACT Patient Research Partner, Sydney, NSW; Institute of Bone and Joint Research, Kolling Institute of Medical Research, Sydney, NSW; Department of Rheumatology, Royal North Shore Hospital, Sydney, NSW; Northern Clinical School, The University of Sydney, Sydney, NSW, Australia; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada; Department of Psychology, Health and Technology, University of Twente, Enschede, the Netherlands, and OMERACT Patient Research Partner; Medicine Service, VA Medical Center, Birmingham, Alabama; Department of Medicine, School of Medicine, and Division of Epidemiology, School of Public Health, University of Alabama, Birmingham, Alabama, USA; University of Alabama, Birmingham, Alabama, USA; Department of Rheumatology, Concord Hospital, Sydney, NSW, Australia; The Children’s Hospital of Eastern Ontario Research Institute, Ottawa; Department of Pediatrics and School of Rehabilitation Sciences, and Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada; Department of Pharmacy, Sint Maartenskliniek, Ubbergen, the Netherlands; Centre for Epidemiology Versus Arthritis, Centre for Musculoskeletal Research, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester; UK National Institute for Health Research (NIHR) Manchester Biomedical Research Centre, Manchester University Hospitals National Health Service (NHS) Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK; Department of Rheumatology, Canberra Hospital, Canberra, ACT, Australia. The work reported in this manuscript was supported by the 2018 Arthritis Australia Project Grant. AK is supported by the Australian Government Research Training Scholarship. SV is supported by Versus Arthritis (grant number 20385) and NIHR Manchester Biomedical Research Centre. RC (The Parker Institute, Copenhagen University Hospital) is supported by a core grant from the Oak Foundation (OCAY-13-309). The funders had no role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript. A. Kelly, MBBS, FRACP, College of Health and Medicine, Australian National University, and Canberra Rheumatology, and Centre for Kidney Research, The Children’s Hospital at Westmead; L. Crimston-Smith, BN, College of Health and Medicine, Australian National University, and Canberra Rheumatology; A. Tong, PhD, Professor, Centre for Kidney Research, The Children’s Hospital at Westmead, and Sydney School of Public Health, The University of Sydney; S.J. Bartlett, PhD, Professor, Department of Medicine, McGill University and Research Institute, McGill University Health Centres, and Division of Rheumatology, Johns Hopkins School of Medicine; C.L. Bekker, PhD, Department of Pharmacy, Radboud University Medical Centre; R. Christensen, Musculoskeletal Statistics Unit, the Parker Institute, Copenhagen University Hospital, and the Research Unit of Rheumatology, Department of Clinical Research, University of Southern Denmark, Odense University Hospital; M.A. De Vera, PhD, Assistant Professor, Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, The University of British Columbia, and Arthritis Research Canada; M. de Wit, PhD, OMERACT Patient Research Partner; V. Evans, PhD, Clear Vision Consulting, and OMERACT Patient Research Partner, and Discipline of Optometry, University of Canberra; M. Gill, BA, Dragon Claw Website, and OMERACT Patient Research Partner; L. March, PhD, Professor, Institute of Bone and Joint Research, Kolling Institute of Medical Research, and the Department of Rheumatology, Royal North Shore Hospital, and the Northern Clinical School, The University of Sydney; K. Manera, MIPH, Centre for Kidney Research, The Children’s Hospital at Westmead, and the Sydney School of Public Health, The University of Sydney; R. Nieuwlaat, PhD, Associate Professor, Department of Health Research Methods, Evidence, and Impact, McMaster University; S. Salmasi, MSc, Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, University of British Columbia, and Arthritis Research Canada; M. Scholte-Voshaar, MSc, Department of Psychology, Health and Technology, University of Twente, and OMERACT Patient Research Partner; J.A. Singh, MD, Professor, Medicine Service, VA Medical Center, and Department of Medicine, School of Medicine, and Division of Epidemiology, School of Public Health, University of Alabama; D. Sumpton, MBBS, FRACP, Centre for Kidney Research, The Children’s Hospital at Westmead, Sydney, and Sydney School of Public Health, The University of Sydney, and Department of Rheumatology, Concord Hospital; K. Toupin-April, PhD, Associate Scientist, The Children’s Hospital of Eastern Ontario Research Institute, and Assistant Professor, the Department of Pediatrics and School of Rehabilitation Sciences, University of Ottawa; P. Tugwell, MD, Professor, Department of Medicine, University of Ottawa; B. van den Bemt, PhD, Assistant Professor, Department of Pharmacy, Radboud University Medical Centre, and Department of Pharmacy, Sint Maartenskliniek; S. Verstappen, PhD, Reader, Centre for Epidemiology Versus Arthritis, Centre for Musculoskeletal Research, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, and NIHR Manchester Biomedical Research Centre, Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre; K. Tymms, MBBS, FRACP, Associate Professor, College of Health and Medicine, Australian National University, and Canberra Rheumatology, and Department of Rheumatology, Canberra Hospital. Address correspondence to A. Kelly, 40 Marcus Clarke St., Canberra City, ACT 2601, Australia. Email: ayano.kelly@anu.edu.au. Accepted for publication December 6, 2019.
Maarten de Wit
From the College of Health and Medicine, Australian National University, Canberra, ACT; Canberra Rheumatology, Canberra, ACT; Centre for Kidney Research, The Children’s Hospital at Westmead, Sydney, NSW; Sydney School of Public Health, The University of Sydney, Sydney, NSW, Australia; Department of Medicine, McGill University and Research Institute, McGill University Health Centres, Montreal, Quebec, Canada; Division of Rheumatology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA; Department of Pharmacy, Radboud University Medical Centre, Nijmegen, the Netherlands; Musculoskeletal Statistics Unit, the Parker Institute, Copenhagen University Hospital, Copenhagen, Denmark; Research Unit of Rheumatology, Department of Clinical Research, University of Southern Denmark, Odense University Hospital, Odense, Denmark; Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver; Arthritis Research Canada, Richmond, British Columbia, Canada; OMERACT Patient Research Partner, the Netherlands; Clear Vision Consulting, and OMERACT Patient Research Partner, Canberra, ACT; Discipline of Optometry, University of Canberra, Canberra, ACT; Dragon Claw Website, and OMERACT Patient Research Partner, Sydney, NSW; Institute of Bone and Joint Research, Kolling Institute of Medical Research, Sydney, NSW; Department of Rheumatology, Royal North Shore Hospital, Sydney, NSW; Northern Clinical School, The University of Sydney, Sydney, NSW, Australia; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada; Department of Psychology, Health and Technology, University of Twente, Enschede, the Netherlands, and OMERACT Patient Research Partner; Medicine Service, VA Medical Center, Birmingham, Alabama; Department of Medicine, School of Medicine, and Division of Epidemiology, School of Public Health, University of Alabama, Birmingham, Alabama, USA; University of Alabama, Birmingham, Alabama, USA; Department of Rheumatology, Concord Hospital, Sydney, NSW, Australia; The Children’s Hospital of Eastern Ontario Research Institute, Ottawa; Department of Pediatrics and School of Rehabilitation Sciences, and Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada; Department of Pharmacy, Sint Maartenskliniek, Ubbergen, the Netherlands; Centre for Epidemiology Versus Arthritis, Centre for Musculoskeletal Research, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester; UK National Institute for Health Research (NIHR) Manchester Biomedical Research Centre, Manchester University Hospitals National Health Service (NHS) Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK; Department of Rheumatology, Canberra Hospital, Canberra, ACT, Australia. The work reported in this manuscript was supported by the 2018 Arthritis Australia Project Grant. AK is supported by the Australian Government Research Training Scholarship. SV is supported by Versus Arthritis (grant number 20385) and NIHR Manchester Biomedical Research Centre. RC (The Parker Institute, Copenhagen University Hospital) is supported by a core grant from the Oak Foundation (OCAY-13-309). The funders had no role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript. A. Kelly, MBBS, FRACP, College of Health and Medicine, Australian National University, and Canberra Rheumatology, and Centre for Kidney Research, The Children’s Hospital at Westmead; L. Crimston-Smith, BN, College of Health and Medicine, Australian National University, and Canberra Rheumatology; A. Tong, PhD, Professor, Centre for Kidney Research, The Children’s Hospital at Westmead, and Sydney School of Public Health, The University of Sydney; S.J. Bartlett, PhD, Professor, Department of Medicine, McGill University and Research Institute, McGill University Health Centres, and Division of Rheumatology, Johns Hopkins School of Medicine; C.L. Bekker, PhD, Department of Pharmacy, Radboud University Medical Centre; R. Christensen, Musculoskeletal Statistics Unit, the Parker Institute, Copenhagen University Hospital, and the Research Unit of Rheumatology, Department of Clinical Research, University of Southern Denmark, Odense University Hospital; M.A. De Vera, PhD, Assistant Professor, Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, The University of British Columbia, and Arthritis Research Canada; M. de Wit, PhD, OMERACT Patient Research Partner; V. Evans, PhD, Clear Vision Consulting, and OMERACT Patient Research Partner, and Discipline of Optometry, University of Canberra; M. Gill, BA, Dragon Claw Website, and OMERACT Patient Research Partner; L. March, PhD, Professor, Institute of Bone and Joint Research, Kolling Institute of Medical Research, and the Department of Rheumatology, Royal North Shore Hospital, and the Northern Clinical School, The University of Sydney; K. Manera, MIPH, Centre for Kidney Research, The Children’s Hospital at Westmead, and the Sydney School of Public Health, The University of Sydney; R. Nieuwlaat, PhD, Associate Professor, Department of Health Research Methods, Evidence, and Impact, McMaster University; S. Salmasi, MSc, Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, University of British Columbia, and Arthritis Research Canada; M. Scholte-Voshaar, MSc, Department of Psychology, Health and Technology, University of Twente, and OMERACT Patient Research Partner; J.A. Singh, MD, Professor, Medicine Service, VA Medical Center, and Department of Medicine, School of Medicine, and Division of Epidemiology, School of Public Health, University of Alabama; D. Sumpton, MBBS, FRACP, Centre for Kidney Research, The Children’s Hospital at Westmead, Sydney, and Sydney School of Public Health, The University of Sydney, and Department of Rheumatology, Concord Hospital; K. Toupin-April, PhD, Associate Scientist, The Children’s Hospital of Eastern Ontario Research Institute, and Assistant Professor, the Department of Pediatrics and School of Rehabilitation Sciences, University of Ottawa; P. Tugwell, MD, Professor, Department of Medicine, University of Ottawa; B. van den Bemt, PhD, Assistant Professor, Department of Pharmacy, Radboud University Medical Centre, and Department of Pharmacy, Sint Maartenskliniek; S. Verstappen, PhD, Reader, Centre for Epidemiology Versus Arthritis, Centre for Musculoskeletal Research, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, and NIHR Manchester Biomedical Research Centre, Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre; K. Tymms, MBBS, FRACP, Associate Professor, College of Health and Medicine, Australian National University, and Canberra Rheumatology, and Department of Rheumatology, Canberra Hospital. Address correspondence to A. Kelly, 40 Marcus Clarke St., Canberra City, ACT 2601, Australia. Email: ayano.kelly@anu.edu.au. Accepted for publication December 6, 2019.
Vicki Evans
From the College of Health and Medicine, Australian National University, Canberra, ACT; Canberra Rheumatology, Canberra, ACT; Centre for Kidney Research, The Children’s Hospital at Westmead, Sydney, NSW; Sydney School of Public Health, The University of Sydney, Sydney, NSW, Australia; Department of Medicine, McGill University and Research Institute, McGill University Health Centres, Montreal, Quebec, Canada; Division of Rheumatology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA; Department of Pharmacy, Radboud University Medical Centre, Nijmegen, the Netherlands; Musculoskeletal Statistics Unit, the Parker Institute, Copenhagen University Hospital, Copenhagen, Denmark; Research Unit of Rheumatology, Department of Clinical Research, University of Southern Denmark, Odense University Hospital, Odense, Denmark; Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver; Arthritis Research Canada, Richmond, British Columbia, Canada; OMERACT Patient Research Partner, the Netherlands; Clear Vision Consulting, and OMERACT Patient Research Partner, Canberra, ACT; Discipline of Optometry, University of Canberra, Canberra, ACT; Dragon Claw Website, and OMERACT Patient Research Partner, Sydney, NSW; Institute of Bone and Joint Research, Kolling Institute of Medical Research, Sydney, NSW; Department of Rheumatology, Royal North Shore Hospital, Sydney, NSW; Northern Clinical School, The University of Sydney, Sydney, NSW, Australia; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada; Department of Psychology, Health and Technology, University of Twente, Enschede, the Netherlands, and OMERACT Patient Research Partner; Medicine Service, VA Medical Center, Birmingham, Alabama; Department of Medicine, School of Medicine, and Division of Epidemiology, School of Public Health, University of Alabama, Birmingham, Alabama, USA; University of Alabama, Birmingham, Alabama, USA; Department of Rheumatology, Concord Hospital, Sydney, NSW, Australia; The Children’s Hospital of Eastern Ontario Research Institute, Ottawa; Department of Pediatrics and School of Rehabilitation Sciences, and Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada; Department of Pharmacy, Sint Maartenskliniek, Ubbergen, the Netherlands; Centre for Epidemiology Versus Arthritis, Centre for Musculoskeletal Research, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester; UK National Institute for Health Research (NIHR) Manchester Biomedical Research Centre, Manchester University Hospitals National Health Service (NHS) Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK; Department of Rheumatology, Canberra Hospital, Canberra, ACT, Australia. The work reported in this manuscript was supported by the 2018 Arthritis Australia Project Grant. AK is supported by the Australian Government Research Training Scholarship. SV is supported by Versus Arthritis (grant number 20385) and NIHR Manchester Biomedical Research Centre. RC (The Parker Institute, Copenhagen University Hospital) is supported by a core grant from the Oak Foundation (OCAY-13-309). The funders had no role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript. A. Kelly, MBBS, FRACP, College of Health and Medicine, Australian National University, and Canberra Rheumatology, and Centre for Kidney Research, The Children’s Hospital at Westmead; L. Crimston-Smith, BN, College of Health and Medicine, Australian National University, and Canberra Rheumatology; A. Tong, PhD, Professor, Centre for Kidney Research, The Children’s Hospital at Westmead, and Sydney School of Public Health, The University of Sydney; S.J. Bartlett, PhD, Professor, Department of Medicine, McGill University and Research Institute, McGill University Health Centres, and Division of Rheumatology, Johns Hopkins School of Medicine; C.L. Bekker, PhD, Department of Pharmacy, Radboud University Medical Centre; R. Christensen, Musculoskeletal Statistics Unit, the Parker Institute, Copenhagen University Hospital, and the Research Unit of Rheumatology, Department of Clinical Research, University of Southern Denmark, Odense University Hospital; M.A. De Vera, PhD, Assistant Professor, Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, The University of British Columbia, and Arthritis Research Canada; M. de Wit, PhD, OMERACT Patient Research Partner; V. Evans, PhD, Clear Vision Consulting, and OMERACT Patient Research Partner, and Discipline of Optometry, University of Canberra; M. Gill, BA, Dragon Claw Website, and OMERACT Patient Research Partner; L. March, PhD, Professor, Institute of Bone and Joint Research, Kolling Institute of Medical Research, and the Department of Rheumatology, Royal North Shore Hospital, and the Northern Clinical School, The University of Sydney; K. Manera, MIPH, Centre for Kidney Research, The Children’s Hospital at Westmead, and the Sydney School of Public Health, The University of Sydney; R. Nieuwlaat, PhD, Associate Professor, Department of Health Research Methods, Evidence, and Impact, McMaster University; S. Salmasi, MSc, Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, University of British Columbia, and Arthritis Research Canada; M. Scholte-Voshaar, MSc, Department of Psychology, Health and Technology, University of Twente, and OMERACT Patient Research Partner; J.A. Singh, MD, Professor, Medicine Service, VA Medical Center, and Department of Medicine, School of Medicine, and Division of Epidemiology, School of Public Health, University of Alabama; D. Sumpton, MBBS, FRACP, Centre for Kidney Research, The Children’s Hospital at Westmead, Sydney, and Sydney School of Public Health, The University of Sydney, and Department of Rheumatology, Concord Hospital; K. Toupin-April, PhD, Associate Scientist, The Children’s Hospital of Eastern Ontario Research Institute, and Assistant Professor, the Department of Pediatrics and School of Rehabilitation Sciences, University of Ottawa; P. Tugwell, MD, Professor, Department of Medicine, University of Ottawa; B. van den Bemt, PhD, Assistant Professor, Department of Pharmacy, Radboud University Medical Centre, and Department of Pharmacy, Sint Maartenskliniek; S. Verstappen, PhD, Reader, Centre for Epidemiology Versus Arthritis, Centre for Musculoskeletal Research, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, and NIHR Manchester Biomedical Research Centre, Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre; K. Tymms, MBBS, FRACP, Associate Professor, College of Health and Medicine, Australian National University, and Canberra Rheumatology, and Department of Rheumatology, Canberra Hospital. Address correspondence to A. Kelly, 40 Marcus Clarke St., Canberra City, ACT 2601, Australia. Email: ayano.kelly@anu.edu.au. Accepted for publication December 6, 2019.
Michael Gill
From the College of Health and Medicine, Australian National University, Canberra, ACT; Canberra Rheumatology, Canberra, ACT; Centre for Kidney Research, The Children’s Hospital at Westmead, Sydney, NSW; Sydney School of Public Health, The University of Sydney, Sydney, NSW, Australia; Department of Medicine, McGill University and Research Institute, McGill University Health Centres, Montreal, Quebec, Canada; Division of Rheumatology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA; Department of Pharmacy, Radboud University Medical Centre, Nijmegen, the Netherlands; Musculoskeletal Statistics Unit, the Parker Institute, Copenhagen University Hospital, Copenhagen, Denmark; Research Unit of Rheumatology, Department of Clinical Research, University of Southern Denmark, Odense University Hospital, Odense, Denmark; Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver; Arthritis Research Canada, Richmond, British Columbia, Canada; OMERACT Patient Research Partner, the Netherlands; Clear Vision Consulting, and OMERACT Patient Research Partner, Canberra, ACT; Discipline of Optometry, University of Canberra, Canberra, ACT; Dragon Claw Website, and OMERACT Patient Research Partner, Sydney, NSW; Institute of Bone and Joint Research, Kolling Institute of Medical Research, Sydney, NSW; Department of Rheumatology, Royal North Shore Hospital, Sydney, NSW; Northern Clinical School, The University of Sydney, Sydney, NSW, Australia; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada; Department of Psychology, Health and Technology, University of Twente, Enschede, the Netherlands, and OMERACT Patient Research Partner; Medicine Service, VA Medical Center, Birmingham, Alabama; Department of Medicine, School of Medicine, and Division of Epidemiology, School of Public Health, University of Alabama, Birmingham, Alabama, USA; University of Alabama, Birmingham, Alabama, USA; Department of Rheumatology, Concord Hospital, Sydney, NSW, Australia; The Children’s Hospital of Eastern Ontario Research Institute, Ottawa; Department of Pediatrics and School of Rehabilitation Sciences, and Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada; Department of Pharmacy, Sint Maartenskliniek, Ubbergen, the Netherlands; Centre for Epidemiology Versus Arthritis, Centre for Musculoskeletal Research, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester; UK National Institute for Health Research (NIHR) Manchester Biomedical Research Centre, Manchester University Hospitals National Health Service (NHS) Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK; Department of Rheumatology, Canberra Hospital, Canberra, ACT, Australia. The work reported in this manuscript was supported by the 2018 Arthritis Australia Project Grant. AK is supported by the Australian Government Research Training Scholarship. SV is supported by Versus Arthritis (grant number 20385) and NIHR Manchester Biomedical Research Centre. RC (The Parker Institute, Copenhagen University Hospital) is supported by a core grant from the Oak Foundation (OCAY-13-309). The funders had no role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript. A. Kelly, MBBS, FRACP, College of Health and Medicine, Australian National University, and Canberra Rheumatology, and Centre for Kidney Research, The Children’s Hospital at Westmead; L. Crimston-Smith, BN, College of Health and Medicine, Australian National University, and Canberra Rheumatology; A. Tong, PhD, Professor, Centre for Kidney Research, The Children’s Hospital at Westmead, and Sydney School of Public Health, The University of Sydney; S.J. Bartlett, PhD, Professor, Department of Medicine, McGill University and Research Institute, McGill University Health Centres, and Division of Rheumatology, Johns Hopkins School of Medicine; C.L. Bekker, PhD, Department of Pharmacy, Radboud University Medical Centre; R. Christensen, Musculoskeletal Statistics Unit, the Parker Institute, Copenhagen University Hospital, and the Research Unit of Rheumatology, Department of Clinical Research, University of Southern Denmark, Odense University Hospital; M.A. De Vera, PhD, Assistant Professor, Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, The University of British Columbia, and Arthritis Research Canada; M. de Wit, PhD, OMERACT Patient Research Partner; V. Evans, PhD, Clear Vision Consulting, and OMERACT Patient Research Partner, and Discipline of Optometry, University of Canberra; M. Gill, BA, Dragon Claw Website, and OMERACT Patient Research Partner; L. March, PhD, Professor, Institute of Bone and Joint Research, Kolling Institute of Medical Research, and the Department of Rheumatology, Royal North Shore Hospital, and the Northern Clinical School, The University of Sydney; K. Manera, MIPH, Centre for Kidney Research, The Children’s Hospital at Westmead, and the Sydney School of Public Health, The University of Sydney; R. Nieuwlaat, PhD, Associate Professor, Department of Health Research Methods, Evidence, and Impact, McMaster University; S. Salmasi, MSc, Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, University of British Columbia, and Arthritis Research Canada; M. Scholte-Voshaar, MSc, Department of Psychology, Health and Technology, University of Twente, and OMERACT Patient Research Partner; J.A. Singh, MD, Professor, Medicine Service, VA Medical Center, and Department of Medicine, School of Medicine, and Division of Epidemiology, School of Public Health, University of Alabama; D. Sumpton, MBBS, FRACP, Centre for Kidney Research, The Children’s Hospital at Westmead, Sydney, and Sydney School of Public Health, The University of Sydney, and Department of Rheumatology, Concord Hospital; K. Toupin-April, PhD, Associate Scientist, The Children’s Hospital of Eastern Ontario Research Institute, and Assistant Professor, the Department of Pediatrics and School of Rehabilitation Sciences, University of Ottawa; P. Tugwell, MD, Professor, Department of Medicine, University of Ottawa; B. van den Bemt, PhD, Assistant Professor, Department of Pharmacy, Radboud University Medical Centre, and Department of Pharmacy, Sint Maartenskliniek; S. Verstappen, PhD, Reader, Centre for Epidemiology Versus Arthritis, Centre for Musculoskeletal Research, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, and NIHR Manchester Biomedical Research Centre, Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre; K. Tymms, MBBS, FRACP, Associate Professor, College of Health and Medicine, Australian National University, and Canberra Rheumatology, and Department of Rheumatology, Canberra Hospital. Address correspondence to A. Kelly, 40 Marcus Clarke St., Canberra City, ACT 2601, Australia. Email: ayano.kelly@anu.edu.au. Accepted for publication December 6, 2019.
Lyn March
From the College of Health and Medicine, Australian National University, Canberra, ACT; Canberra Rheumatology, Canberra, ACT; Centre for Kidney Research, The Children’s Hospital at Westmead, Sydney, NSW; Sydney School of Public Health, The University of Sydney, Sydney, NSW, Australia; Department of Medicine, McGill University and Research Institute, McGill University Health Centres, Montreal, Quebec, Canada; Division of Rheumatology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA; Department of Pharmacy, Radboud University Medical Centre, Nijmegen, the Netherlands; Musculoskeletal Statistics Unit, the Parker Institute, Copenhagen University Hospital, Copenhagen, Denmark; Research Unit of Rheumatology, Department of Clinical Research, University of Southern Denmark, Odense University Hospital, Odense, Denmark; Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver; Arthritis Research Canada, Richmond, British Columbia, Canada; OMERACT Patient Research Partner, the Netherlands; Clear Vision Consulting, and OMERACT Patient Research Partner, Canberra, ACT; Discipline of Optometry, University of Canberra, Canberra, ACT; Dragon Claw Website, and OMERACT Patient Research Partner, Sydney, NSW; Institute of Bone and Joint Research, Kolling Institute of Medical Research, Sydney, NSW; Department of Rheumatology, Royal North Shore Hospital, Sydney, NSW; Northern Clinical School, The University of Sydney, Sydney, NSW, Australia; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada; Department of Psychology, Health and Technology, University of Twente, Enschede, the Netherlands, and OMERACT Patient Research Partner; Medicine Service, VA Medical Center, Birmingham, Alabama; Department of Medicine, School of Medicine, and Division of Epidemiology, School of Public Health, University of Alabama, Birmingham, Alabama, USA; University of Alabama, Birmingham, Alabama, USA; Department of Rheumatology, Concord Hospital, Sydney, NSW, Australia; The Children’s Hospital of Eastern Ontario Research Institute, Ottawa; Department of Pediatrics and School of Rehabilitation Sciences, and Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada; Department of Pharmacy, Sint Maartenskliniek, Ubbergen, the Netherlands; Centre for Epidemiology Versus Arthritis, Centre for Musculoskeletal Research, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester; UK National Institute for Health Research (NIHR) Manchester Biomedical Research Centre, Manchester University Hospitals National Health Service (NHS) Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK; Department of Rheumatology, Canberra Hospital, Canberra, ACT, Australia. The work reported in this manuscript was supported by the 2018 Arthritis Australia Project Grant. AK is supported by the Australian Government Research Training Scholarship. SV is supported by Versus Arthritis (grant number 20385) and NIHR Manchester Biomedical Research Centre. RC (The Parker Institute, Copenhagen University Hospital) is supported by a core grant from the Oak Foundation (OCAY-13-309). The funders had no role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript. A. Kelly, MBBS, FRACP, College of Health and Medicine, Australian National University, and Canberra Rheumatology, and Centre for Kidney Research, The Children’s Hospital at Westmead; L. Crimston-Smith, BN, College of Health and Medicine, Australian National University, and Canberra Rheumatology; A. Tong, PhD, Professor, Centre for Kidney Research, The Children’s Hospital at Westmead, and Sydney School of Public Health, The University of Sydney; S.J. Bartlett, PhD, Professor, Department of Medicine, McGill University and Research Institute, McGill University Health Centres, and Division of Rheumatology, Johns Hopkins School of Medicine; C.L. Bekker, PhD, Department of Pharmacy, Radboud University Medical Centre; R. Christensen, Musculoskeletal Statistics Unit, the Parker Institute, Copenhagen University Hospital, and the Research Unit of Rheumatology, Department of Clinical Research, University of Southern Denmark, Odense University Hospital; M.A. De Vera, PhD, Assistant Professor, Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, The University of British Columbia, and Arthritis Research Canada; M. de Wit, PhD, OMERACT Patient Research Partner; V. Evans, PhD, Clear Vision Consulting, and OMERACT Patient Research Partner, and Discipline of Optometry, University of Canberra; M. Gill, BA, Dragon Claw Website, and OMERACT Patient Research Partner; L. March, PhD, Professor, Institute of Bone and Joint Research, Kolling Institute of Medical Research, and the Department of Rheumatology, Royal North Shore Hospital, and the Northern Clinical School, The University of Sydney; K. Manera, MIPH, Centre for Kidney Research, The Children’s Hospital at Westmead, and the Sydney School of Public Health, The University of Sydney; R. Nieuwlaat, PhD, Associate Professor, Department of Health Research Methods, Evidence, and Impact, McMaster University; S. Salmasi, MSc, Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, University of British Columbia, and Arthritis Research Canada; M. Scholte-Voshaar, MSc, Department of Psychology, Health and Technology, University of Twente, and OMERACT Patient Research Partner; J.A. Singh, MD, Professor, Medicine Service, VA Medical Center, and Department of Medicine, School of Medicine, and Division of Epidemiology, School of Public Health, University of Alabama; D. Sumpton, MBBS, FRACP, Centre for Kidney Research, The Children’s Hospital at Westmead, Sydney, and Sydney School of Public Health, The University of Sydney, and Department of Rheumatology, Concord Hospital; K. Toupin-April, PhD, Associate Scientist, The Children’s Hospital of Eastern Ontario Research Institute, and Assistant Professor, the Department of Pediatrics and School of Rehabilitation Sciences, University of Ottawa; P. Tugwell, MD, Professor, Department of Medicine, University of Ottawa; B. van den Bemt, PhD, Assistant Professor, Department of Pharmacy, Radboud University Medical Centre, and Department of Pharmacy, Sint Maartenskliniek; S. Verstappen, PhD, Reader, Centre for Epidemiology Versus Arthritis, Centre for Musculoskeletal Research, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, and NIHR Manchester Biomedical Research Centre, Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre; K. Tymms, MBBS, FRACP, Associate Professor, College of Health and Medicine, Australian National University, and Canberra Rheumatology, and Department of Rheumatology, Canberra Hospital. Address correspondence to A. Kelly, 40 Marcus Clarke St., Canberra City, ACT 2601, Australia. Email: ayano.kelly@anu.edu.au. Accepted for publication December 6, 2019.
Karine Manera
From the College of Health and Medicine, Australian National University, Canberra, ACT; Canberra Rheumatology, Canberra, ACT; Centre for Kidney Research, The Children’s Hospital at Westmead, Sydney, NSW; Sydney School of Public Health, The University of Sydney, Sydney, NSW, Australia; Department of Medicine, McGill University and Research Institute, McGill University Health Centres, Montreal, Quebec, Canada; Division of Rheumatology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA; Department of Pharmacy, Radboud University Medical Centre, Nijmegen, the Netherlands; Musculoskeletal Statistics Unit, the Parker Institute, Copenhagen University Hospital, Copenhagen, Denmark; Research Unit of Rheumatology, Department of Clinical Research, University of Southern Denmark, Odense University Hospital, Odense, Denmark; Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver; Arthritis Research Canada, Richmond, British Columbia, Canada; OMERACT Patient Research Partner, the Netherlands; Clear Vision Consulting, and OMERACT Patient Research Partner, Canberra, ACT; Discipline of Optometry, University of Canberra, Canberra, ACT; Dragon Claw Website, and OMERACT Patient Research Partner, Sydney, NSW; Institute of Bone and Joint Research, Kolling Institute of Medical Research, Sydney, NSW; Department of Rheumatology, Royal North Shore Hospital, Sydney, NSW; Northern Clinical School, The University of Sydney, Sydney, NSW, Australia; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada; Department of Psychology, Health and Technology, University of Twente, Enschede, the Netherlands, and OMERACT Patient Research Partner; Medicine Service, VA Medical Center, Birmingham, Alabama; Department of Medicine, School of Medicine, and Division of Epidemiology, School of Public Health, University of Alabama, Birmingham, Alabama, USA; University of Alabama, Birmingham, Alabama, USA; Department of Rheumatology, Concord Hospital, Sydney, NSW, Australia; The Children’s Hospital of Eastern Ontario Research Institute, Ottawa; Department of Pediatrics and School of Rehabilitation Sciences, and Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada; Department of Pharmacy, Sint Maartenskliniek, Ubbergen, the Netherlands; Centre for Epidemiology Versus Arthritis, Centre for Musculoskeletal Research, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester; UK National Institute for Health Research (NIHR) Manchester Biomedical Research Centre, Manchester University Hospitals National Health Service (NHS) Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK; Department of Rheumatology, Canberra Hospital, Canberra, ACT, Australia. The work reported in this manuscript was supported by the 2018 Arthritis Australia Project Grant. AK is supported by the Australian Government Research Training Scholarship. SV is supported by Versus Arthritis (grant number 20385) and NIHR Manchester Biomedical Research Centre. RC (The Parker Institute, Copenhagen University Hospital) is supported by a core grant from the Oak Foundation (OCAY-13-309). The funders had no role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript. A. Kelly, MBBS, FRACP, College of Health and Medicine, Australian National University, and Canberra Rheumatology, and Centre for Kidney Research, The Children’s Hospital at Westmead; L. Crimston-Smith, BN, College of Health and Medicine, Australian National University, and Canberra Rheumatology; A. Tong, PhD, Professor, Centre for Kidney Research, The Children’s Hospital at Westmead, and Sydney School of Public Health, The University of Sydney; S.J. Bartlett, PhD, Professor, Department of Medicine, McGill University and Research Institute, McGill University Health Centres, and Division of Rheumatology, Johns Hopkins School of Medicine; C.L. Bekker, PhD, Department of Pharmacy, Radboud University Medical Centre; R. Christensen, Musculoskeletal Statistics Unit, the Parker Institute, Copenhagen University Hospital, and the Research Unit of Rheumatology, Department of Clinical Research, University of Southern Denmark, Odense University Hospital; M.A. De Vera, PhD, Assistant Professor, Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, The University of British Columbia, and Arthritis Research Canada; M. de Wit, PhD, OMERACT Patient Research Partner; V. Evans, PhD, Clear Vision Consulting, and OMERACT Patient Research Partner, and Discipline of Optometry, University of Canberra; M. Gill, BA, Dragon Claw Website, and OMERACT Patient Research Partner; L. March, PhD, Professor, Institute of Bone and Joint Research, Kolling Institute of Medical Research, and the Department of Rheumatology, Royal North Shore Hospital, and the Northern Clinical School, The University of Sydney; K. Manera, MIPH, Centre for Kidney Research, The Children’s Hospital at Westmead, and the Sydney School of Public Health, The University of Sydney; R. Nieuwlaat, PhD, Associate Professor, Department of Health Research Methods, Evidence, and Impact, McMaster University; S. Salmasi, MSc, Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, University of British Columbia, and Arthritis Research Canada; M. Scholte-Voshaar, MSc, Department of Psychology, Health and Technology, University of Twente, and OMERACT Patient Research Partner; J.A. Singh, MD, Professor, Medicine Service, VA Medical Center, and Department of Medicine, School of Medicine, and Division of Epidemiology, School of Public Health, University of Alabama; D. Sumpton, MBBS, FRACP, Centre for Kidney Research, The Children’s Hospital at Westmead, Sydney, and Sydney School of Public Health, The University of Sydney, and Department of Rheumatology, Concord Hospital; K. Toupin-April, PhD, Associate Scientist, The Children’s Hospital of Eastern Ontario Research Institute, and Assistant Professor, the Department of Pediatrics and School of Rehabilitation Sciences, University of Ottawa; P. Tugwell, MD, Professor, Department of Medicine, University of Ottawa; B. van den Bemt, PhD, Assistant Professor, Department of Pharmacy, Radboud University Medical Centre, and Department of Pharmacy, Sint Maartenskliniek; S. Verstappen, PhD, Reader, Centre for Epidemiology Versus Arthritis, Centre for Musculoskeletal Research, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, and NIHR Manchester Biomedical Research Centre, Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre; K. Tymms, MBBS, FRACP, Associate Professor, College of Health and Medicine, Australian National University, and Canberra Rheumatology, and Department of Rheumatology, Canberra Hospital. Address correspondence to A. Kelly, 40 Marcus Clarke St., Canberra City, ACT 2601, Australia. Email: ayano.kelly@anu.edu.au. Accepted for publication December 6, 2019.
Robby Nieuwlaat
From the College of Health and Medicine, Australian National University, Canberra, ACT; Canberra Rheumatology, Canberra, ACT; Centre for Kidney Research, The Children’s Hospital at Westmead, Sydney, NSW; Sydney School of Public Health, The University of Sydney, Sydney, NSW, Australia; Department of Medicine, McGill University and Research Institute, McGill University Health Centres, Montreal, Quebec, Canada; Division of Rheumatology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA; Department of Pharmacy, Radboud University Medical Centre, Nijmegen, the Netherlands; Musculoskeletal Statistics Unit, the Parker Institute, Copenhagen University Hospital, Copenhagen, Denmark; Research Unit of Rheumatology, Department of Clinical Research, University of Southern Denmark, Odense University Hospital, Odense, Denmark; Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver; Arthritis Research Canada, Richmond, British Columbia, Canada; OMERACT Patient Research Partner, the Netherlands; Clear Vision Consulting, and OMERACT Patient Research Partner, Canberra, ACT; Discipline of Optometry, University of Canberra, Canberra, ACT; Dragon Claw Website, and OMERACT Patient Research Partner, Sydney, NSW; Institute of Bone and Joint Research, Kolling Institute of Medical Research, Sydney, NSW; Department of Rheumatology, Royal North Shore Hospital, Sydney, NSW; Northern Clinical School, The University of Sydney, Sydney, NSW, Australia; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada; Department of Psychology, Health and Technology, University of Twente, Enschede, the Netherlands, and OMERACT Patient Research Partner; Medicine Service, VA Medical Center, Birmingham, Alabama; Department of Medicine, School of Medicine, and Division of Epidemiology, School of Public Health, University of Alabama, Birmingham, Alabama, USA; University of Alabama, Birmingham, Alabama, USA; Department of Rheumatology, Concord Hospital, Sydney, NSW, Australia; The Children’s Hospital of Eastern Ontario Research Institute, Ottawa; Department of Pediatrics and School of Rehabilitation Sciences, and Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada; Department of Pharmacy, Sint Maartenskliniek, Ubbergen, the Netherlands; Centre for Epidemiology Versus Arthritis, Centre for Musculoskeletal Research, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester; UK National Institute for Health Research (NIHR) Manchester Biomedical Research Centre, Manchester University Hospitals National Health Service (NHS) Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK; Department of Rheumatology, Canberra Hospital, Canberra, ACT, Australia. The work reported in this manuscript was supported by the 2018 Arthritis Australia Project Grant. AK is supported by the Australian Government Research Training Scholarship. SV is supported by Versus Arthritis (grant number 20385) and NIHR Manchester Biomedical Research Centre. RC (The Parker Institute, Copenhagen University Hospital) is supported by a core grant from the Oak Foundation (OCAY-13-309). The funders had no role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript. A. Kelly, MBBS, FRACP, College of Health and Medicine, Australian National University, and Canberra Rheumatology, and Centre for Kidney Research, The Children’s Hospital at Westmead; L. Crimston-Smith, BN, College of Health and Medicine, Australian National University, and Canberra Rheumatology; A. Tong, PhD, Professor, Centre for Kidney Research, The Children’s Hospital at Westmead, and Sydney School of Public Health, The University of Sydney; S.J. Bartlett, PhD, Professor, Department of Medicine, McGill University and Research Institute, McGill University Health Centres, and Division of Rheumatology, Johns Hopkins School of Medicine; C.L. Bekker, PhD, Department of Pharmacy, Radboud University Medical Centre; R. Christensen, Musculoskeletal Statistics Unit, the Parker Institute, Copenhagen University Hospital, and the Research Unit of Rheumatology, Department of Clinical Research, University of Southern Denmark, Odense University Hospital; M.A. De Vera, PhD, Assistant Professor, Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, The University of British Columbia, and Arthritis Research Canada; M. de Wit, PhD, OMERACT Patient Research Partner; V. Evans, PhD, Clear Vision Consulting, and OMERACT Patient Research Partner, and Discipline of Optometry, University of Canberra; M. Gill, BA, Dragon Claw Website, and OMERACT Patient Research Partner; L. March, PhD, Professor, Institute of Bone and Joint Research, Kolling Institute of Medical Research, and the Department of Rheumatology, Royal North Shore Hospital, and the Northern Clinical School, The University of Sydney; K. Manera, MIPH, Centre for Kidney Research, The Children’s Hospital at Westmead, and the Sydney School of Public Health, The University of Sydney; R. Nieuwlaat, PhD, Associate Professor, Department of Health Research Methods, Evidence, and Impact, McMaster University; S. Salmasi, MSc, Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, University of British Columbia, and Arthritis Research Canada; M. Scholte-Voshaar, MSc, Department of Psychology, Health and Technology, University of Twente, and OMERACT Patient Research Partner; J.A. Singh, MD, Professor, Medicine Service, VA Medical Center, and Department of Medicine, School of Medicine, and Division of Epidemiology, School of Public Health, University of Alabama; D. Sumpton, MBBS, FRACP, Centre for Kidney Research, The Children’s Hospital at Westmead, Sydney, and Sydney School of Public Health, The University of Sydney, and Department of Rheumatology, Concord Hospital; K. Toupin-April, PhD, Associate Scientist, The Children’s Hospital of Eastern Ontario Research Institute, and Assistant Professor, the Department of Pediatrics and School of Rehabilitation Sciences, University of Ottawa; P. Tugwell, MD, Professor, Department of Medicine, University of Ottawa; B. van den Bemt, PhD, Assistant Professor, Department of Pharmacy, Radboud University Medical Centre, and Department of Pharmacy, Sint Maartenskliniek; S. Verstappen, PhD, Reader, Centre for Epidemiology Versus Arthritis, Centre for Musculoskeletal Research, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, and NIHR Manchester Biomedical Research Centre, Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre; K. Tymms, MBBS, FRACP, Associate Professor, College of Health and Medicine, Australian National University, and Canberra Rheumatology, and Department of Rheumatology, Canberra Hospital. Address correspondence to A. Kelly, 40 Marcus Clarke St., Canberra City, ACT 2601, Australia. Email: ayano.kelly@anu.edu.au. Accepted for publication December 6, 2019.
Shahrzad Salmasi
From the College of Health and Medicine, Australian National University, Canberra, ACT; Canberra Rheumatology, Canberra, ACT; Centre for Kidney Research, The Children’s Hospital at Westmead, Sydney, NSW; Sydney School of Public Health, The University of Sydney, Sydney, NSW, Australia; Department of Medicine, McGill University and Research Institute, McGill University Health Centres, Montreal, Quebec, Canada; Division of Rheumatology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA; Department of Pharmacy, Radboud University Medical Centre, Nijmegen, the Netherlands; Musculoskeletal Statistics Unit, the Parker Institute, Copenhagen University Hospital, Copenhagen, Denmark; Research Unit of Rheumatology, Department of Clinical Research, University of Southern Denmark, Odense University Hospital, Odense, Denmark; Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver; Arthritis Research Canada, Richmond, British Columbia, Canada; OMERACT Patient Research Partner, the Netherlands; Clear Vision Consulting, and OMERACT Patient Research Partner, Canberra, ACT; Discipline of Optometry, University of Canberra, Canberra, ACT; Dragon Claw Website, and OMERACT Patient Research Partner, Sydney, NSW; Institute of Bone and Joint Research, Kolling Institute of Medical Research, Sydney, NSW; Department of Rheumatology, Royal North Shore Hospital, Sydney, NSW; Northern Clinical School, The University of Sydney, Sydney, NSW, Australia; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada; Department of Psychology, Health and Technology, University of Twente, Enschede, the Netherlands, and OMERACT Patient Research Partner; Medicine Service, VA Medical Center, Birmingham, Alabama; Department of Medicine, School of Medicine, and Division of Epidemiology, School of Public Health, University of Alabama, Birmingham, Alabama, USA; University of Alabama, Birmingham, Alabama, USA; Department of Rheumatology, Concord Hospital, Sydney, NSW, Australia; The Children’s Hospital of Eastern Ontario Research Institute, Ottawa; Department of Pediatrics and School of Rehabilitation Sciences, and Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada; Department of Pharmacy, Sint Maartenskliniek, Ubbergen, the Netherlands; Centre for Epidemiology Versus Arthritis, Centre for Musculoskeletal Research, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester; UK National Institute for Health Research (NIHR) Manchester Biomedical Research Centre, Manchester University Hospitals National Health Service (NHS) Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK; Department of Rheumatology, Canberra Hospital, Canberra, ACT, Australia. The work reported in this manuscript was supported by the 2018 Arthritis Australia Project Grant. AK is supported by the Australian Government Research Training Scholarship. SV is supported by Versus Arthritis (grant number 20385) and NIHR Manchester Biomedical Research Centre. RC (The Parker Institute, Copenhagen University Hospital) is supported by a core grant from the Oak Foundation (OCAY-13-309). The funders had no role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript. A. Kelly, MBBS, FRACP, College of Health and Medicine, Australian National University, and Canberra Rheumatology, and Centre for Kidney Research, The Children’s Hospital at Westmead; L. Crimston-Smith, BN, College of Health and Medicine, Australian National University, and Canberra Rheumatology; A. Tong, PhD, Professor, Centre for Kidney Research, The Children’s Hospital at Westmead, and Sydney School of Public Health, The University of Sydney; S.J. Bartlett, PhD, Professor, Department of Medicine, McGill University and Research Institute, McGill University Health Centres, and Division of Rheumatology, Johns Hopkins School of Medicine; C.L. Bekker, PhD, Department of Pharmacy, Radboud University Medical Centre; R. Christensen, Musculoskeletal Statistics Unit, the Parker Institute, Copenhagen University Hospital, and the Research Unit of Rheumatology, Department of Clinical Research, University of Southern Denmark, Odense University Hospital; M.A. De Vera, PhD, Assistant Professor, Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, The University of British Columbia, and Arthritis Research Canada; M. de Wit, PhD, OMERACT Patient Research Partner; V. Evans, PhD, Clear Vision Consulting, and OMERACT Patient Research Partner, and Discipline of Optometry, University of Canberra; M. Gill, BA, Dragon Claw Website, and OMERACT Patient Research Partner; L. March, PhD, Professor, Institute of Bone and Joint Research, Kolling Institute of Medical Research, and the Department of Rheumatology, Royal North Shore Hospital, and the Northern Clinical School, The University of Sydney; K. Manera, MIPH, Centre for Kidney Research, The Children’s Hospital at Westmead, and the Sydney School of Public Health, The University of Sydney; R. Nieuwlaat, PhD, Associate Professor, Department of Health Research Methods, Evidence, and Impact, McMaster University; S. Salmasi, MSc, Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, University of British Columbia, and Arthritis Research Canada; M. Scholte-Voshaar, MSc, Department of Psychology, Health and Technology, University of Twente, and OMERACT Patient Research Partner; J.A. Singh, MD, Professor, Medicine Service, VA Medical Center, and Department of Medicine, School of Medicine, and Division of Epidemiology, School of Public Health, University of Alabama; D. Sumpton, MBBS, FRACP, Centre for Kidney Research, The Children’s Hospital at Westmead, Sydney, and Sydney School of Public Health, The University of Sydney, and Department of Rheumatology, Concord Hospital; K. Toupin-April, PhD, Associate Scientist, The Children’s Hospital of Eastern Ontario Research Institute, and Assistant Professor, the Department of Pediatrics and School of Rehabilitation Sciences, University of Ottawa; P. Tugwell, MD, Professor, Department of Medicine, University of Ottawa; B. van den Bemt, PhD, Assistant Professor, Department of Pharmacy, Radboud University Medical Centre, and Department of Pharmacy, Sint Maartenskliniek; S. Verstappen, PhD, Reader, Centre for Epidemiology Versus Arthritis, Centre for Musculoskeletal Research, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, and NIHR Manchester Biomedical Research Centre, Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre; K. Tymms, MBBS, FRACP, Associate Professor, College of Health and Medicine, Australian National University, and Canberra Rheumatology, and Department of Rheumatology, Canberra Hospital. Address correspondence to A. Kelly, 40 Marcus Clarke St., Canberra City, ACT 2601, Australia. Email: ayano.kelly@anu.edu.au. Accepted for publication December 6, 2019.
Marieke Scholte-Voshaar
From the College of Health and Medicine, Australian National University, Canberra, ACT; Canberra Rheumatology, Canberra, ACT; Centre for Kidney Research, The Children’s Hospital at Westmead, Sydney, NSW; Sydney School of Public Health, The University of Sydney, Sydney, NSW, Australia; Department of Medicine, McGill University and Research Institute, McGill University Health Centres, Montreal, Quebec, Canada; Division of Rheumatology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA; Department of Pharmacy, Radboud University Medical Centre, Nijmegen, the Netherlands; Musculoskeletal Statistics Unit, the Parker Institute, Copenhagen University Hospital, Copenhagen, Denmark; Research Unit of Rheumatology, Department of Clinical Research, University of Southern Denmark, Odense University Hospital, Odense, Denmark; Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver; Arthritis Research Canada, Richmond, British Columbia, Canada; OMERACT Patient Research Partner, the Netherlands; Clear Vision Consulting, and OMERACT Patient Research Partner, Canberra, ACT; Discipline of Optometry, University of Canberra, Canberra, ACT; Dragon Claw Website, and OMERACT Patient Research Partner, Sydney, NSW; Institute of Bone and Joint Research, Kolling Institute of Medical Research, Sydney, NSW; Department of Rheumatology, Royal North Shore Hospital, Sydney, NSW; Northern Clinical School, The University of Sydney, Sydney, NSW, Australia; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada; Department of Psychology, Health and Technology, University of Twente, Enschede, the Netherlands, and OMERACT Patient Research Partner; Medicine Service, VA Medical Center, Birmingham, Alabama; Department of Medicine, School of Medicine, and Division of Epidemiology, School of Public Health, University of Alabama, Birmingham, Alabama, USA; University of Alabama, Birmingham, Alabama, USA; Department of Rheumatology, Concord Hospital, Sydney, NSW, Australia; The Children’s Hospital of Eastern Ontario Research Institute, Ottawa; Department of Pediatrics and School of Rehabilitation Sciences, and Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada; Department of Pharmacy, Sint Maartenskliniek, Ubbergen, the Netherlands; Centre for Epidemiology Versus Arthritis, Centre for Musculoskeletal Research, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester; UK National Institute for Health Research (NIHR) Manchester Biomedical Research Centre, Manchester University Hospitals National Health Service (NHS) Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK; Department of Rheumatology, Canberra Hospital, Canberra, ACT, Australia. The work reported in this manuscript was supported by the 2018 Arthritis Australia Project Grant. AK is supported by the Australian Government Research Training Scholarship. SV is supported by Versus Arthritis (grant number 20385) and NIHR Manchester Biomedical Research Centre. RC (The Parker Institute, Copenhagen University Hospital) is supported by a core grant from the Oak Foundation (OCAY-13-309). The funders had no role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript. A. Kelly, MBBS, FRACP, College of Health and Medicine, Australian National University, and Canberra Rheumatology, and Centre for Kidney Research, The Children’s Hospital at Westmead; L. Crimston-Smith, BN, College of Health and Medicine, Australian National University, and Canberra Rheumatology; A. Tong, PhD, Professor, Centre for Kidney Research, The Children’s Hospital at Westmead, and Sydney School of Public Health, The University of Sydney; S.J. Bartlett, PhD, Professor, Department of Medicine, McGill University and Research Institute, McGill University Health Centres, and Division of Rheumatology, Johns Hopkins School of Medicine; C.L. Bekker, PhD, Department of Pharmacy, Radboud University Medical Centre; R. Christensen, Musculoskeletal Statistics Unit, the Parker Institute, Copenhagen University Hospital, and the Research Unit of Rheumatology, Department of Clinical Research, University of Southern Denmark, Odense University Hospital; M.A. De Vera, PhD, Assistant Professor, Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, The University of British Columbia, and Arthritis Research Canada; M. de Wit, PhD, OMERACT Patient Research Partner; V. Evans, PhD, Clear Vision Consulting, and OMERACT Patient Research Partner, and Discipline of Optometry, University of Canberra; M. Gill, BA, Dragon Claw Website, and OMERACT Patient Research Partner; L. March, PhD, Professor, Institute of Bone and Joint Research, Kolling Institute of Medical Research, and the Department of Rheumatology, Royal North Shore Hospital, and the Northern Clinical School, The University of Sydney; K. Manera, MIPH, Centre for Kidney Research, The Children’s Hospital at Westmead, and the Sydney School of Public Health, The University of Sydney; R. Nieuwlaat, PhD, Associate Professor, Department of Health Research Methods, Evidence, and Impact, McMaster University; S. Salmasi, MSc, Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, University of British Columbia, and Arthritis Research Canada; M. Scholte-Voshaar, MSc, Department of Psychology, Health and Technology, University of Twente, and OMERACT Patient Research Partner; J.A. Singh, MD, Professor, Medicine Service, VA Medical Center, and Department of Medicine, School of Medicine, and Division of Epidemiology, School of Public Health, University of Alabama; D. Sumpton, MBBS, FRACP, Centre for Kidney Research, The Children’s Hospital at Westmead, Sydney, and Sydney School of Public Health, The University of Sydney, and Department of Rheumatology, Concord Hospital; K. Toupin-April, PhD, Associate Scientist, The Children’s Hospital of Eastern Ontario Research Institute, and Assistant Professor, the Department of Pediatrics and School of Rehabilitation Sciences, University of Ottawa; P. Tugwell, MD, Professor, Department of Medicine, University of Ottawa; B. van den Bemt, PhD, Assistant Professor, Department of Pharmacy, Radboud University Medical Centre, and Department of Pharmacy, Sint Maartenskliniek; S. Verstappen, PhD, Reader, Centre for Epidemiology Versus Arthritis, Centre for Musculoskeletal Research, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, and NIHR Manchester Biomedical Research Centre, Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre; K. Tymms, MBBS, FRACP, Associate Professor, College of Health and Medicine, Australian National University, and Canberra Rheumatology, and Department of Rheumatology, Canberra Hospital. Address correspondence to A. Kelly, 40 Marcus Clarke St., Canberra City, ACT 2601, Australia. Email: ayano.kelly@anu.edu.au. Accepted for publication December 6, 2019.
Jasvinder A. Singh
From the College of Health and Medicine, Australian National University, Canberra, ACT; Canberra Rheumatology, Canberra, ACT; Centre for Kidney Research, The Children’s Hospital at Westmead, Sydney, NSW; Sydney School of Public Health, The University of Sydney, Sydney, NSW, Australia; Department of Medicine, McGill University and Research Institute, McGill University Health Centres, Montreal, Quebec, Canada; Division of Rheumatology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA; Department of Pharmacy, Radboud University Medical Centre, Nijmegen, the Netherlands; Musculoskeletal Statistics Unit, the Parker Institute, Copenhagen University Hospital, Copenhagen, Denmark; Research Unit of Rheumatology, Department of Clinical Research, University of Southern Denmark, Odense University Hospital, Odense, Denmark; Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver; Arthritis Research Canada, Richmond, British Columbia, Canada; OMERACT Patient Research Partner, the Netherlands; Clear Vision Consulting, and OMERACT Patient Research Partner, Canberra, ACT; Discipline of Optometry, University of Canberra, Canberra, ACT; Dragon Claw Website, and OMERACT Patient Research Partner, Sydney, NSW; Institute of Bone and Joint Research, Kolling Institute of Medical Research, Sydney, NSW; Department of Rheumatology, Royal North Shore Hospital, Sydney, NSW; Northern Clinical School, The University of Sydney, Sydney, NSW, Australia; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada; Department of Psychology, Health and Technology, University of Twente, Enschede, the Netherlands, and OMERACT Patient Research Partner; Medicine Service, VA Medical Center, Birmingham, Alabama; Department of Medicine, School of Medicine, and Division of Epidemiology, School of Public Health, University of Alabama, Birmingham, Alabama, USA; University of Alabama, Birmingham, Alabama, USA; Department of Rheumatology, Concord Hospital, Sydney, NSW, Australia; The Children’s Hospital of Eastern Ontario Research Institute, Ottawa; Department of Pediatrics and School of Rehabilitation Sciences, and Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada; Department of Pharmacy, Sint Maartenskliniek, Ubbergen, the Netherlands; Centre for Epidemiology Versus Arthritis, Centre for Musculoskeletal Research, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester; UK National Institute for Health Research (NIHR) Manchester Biomedical Research Centre, Manchester University Hospitals National Health Service (NHS) Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK; Department of Rheumatology, Canberra Hospital, Canberra, ACT, Australia. The work reported in this manuscript was supported by the 2018 Arthritis Australia Project Grant. AK is supported by the Australian Government Research Training Scholarship. SV is supported by Versus Arthritis (grant number 20385) and NIHR Manchester Biomedical Research Centre. RC (The Parker Institute, Copenhagen University Hospital) is supported by a core grant from the Oak Foundation (OCAY-13-309). The funders had no role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript. A. Kelly, MBBS, FRACP, College of Health and Medicine, Australian National University, and Canberra Rheumatology, and Centre for Kidney Research, The Children’s Hospital at Westmead; L. Crimston-Smith, BN, College of Health and Medicine, Australian National University, and Canberra Rheumatology; A. Tong, PhD, Professor, Centre for Kidney Research, The Children’s Hospital at Westmead, and Sydney School of Public Health, The University of Sydney; S.J. Bartlett, PhD, Professor, Department of Medicine, McGill University and Research Institute, McGill University Health Centres, and Division of Rheumatology, Johns Hopkins School of Medicine; C.L. Bekker, PhD, Department of Pharmacy, Radboud University Medical Centre; R. Christensen, Musculoskeletal Statistics Unit, the Parker Institute, Copenhagen University Hospital, and the Research Unit of Rheumatology, Department of Clinical Research, University of Southern Denmark, Odense University Hospital; M.A. De Vera, PhD, Assistant Professor, Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, The University of British Columbia, and Arthritis Research Canada; M. de Wit, PhD, OMERACT Patient Research Partner; V. Evans, PhD, Clear Vision Consulting, and OMERACT Patient Research Partner, and Discipline of Optometry, University of Canberra; M. Gill, BA, Dragon Claw Website, and OMERACT Patient Research Partner; L. March, PhD, Professor, Institute of Bone and Joint Research, Kolling Institute of Medical Research, and the Department of Rheumatology, Royal North Shore Hospital, and the Northern Clinical School, The University of Sydney; K. Manera, MIPH, Centre for Kidney Research, The Children’s Hospital at Westmead, and the Sydney School of Public Health, The University of Sydney; R. Nieuwlaat, PhD, Associate Professor, Department of Health Research Methods, Evidence, and Impact, McMaster University; S. Salmasi, MSc, Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, University of British Columbia, and Arthritis Research Canada; M. Scholte-Voshaar, MSc, Department of Psychology, Health and Technology, University of Twente, and OMERACT Patient Research Partner; J.A. Singh, MD, Professor, Medicine Service, VA Medical Center, and Department of Medicine, School of Medicine, and Division of Epidemiology, School of Public Health, University of Alabama; D. Sumpton, MBBS, FRACP, Centre for Kidney Research, The Children’s Hospital at Westmead, Sydney, and Sydney School of Public Health, The University of Sydney, and Department of Rheumatology, Concord Hospital; K. Toupin-April, PhD, Associate Scientist, The Children’s Hospital of Eastern Ontario Research Institute, and Assistant Professor, the Department of Pediatrics and School of Rehabilitation Sciences, University of Ottawa; P. Tugwell, MD, Professor, Department of Medicine, University of Ottawa; B. van den Bemt, PhD, Assistant Professor, Department of Pharmacy, Radboud University Medical Centre, and Department of Pharmacy, Sint Maartenskliniek; S. Verstappen, PhD, Reader, Centre for Epidemiology Versus Arthritis, Centre for Musculoskeletal Research, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, and NIHR Manchester Biomedical Research Centre, Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre; K. Tymms, MBBS, FRACP, Associate Professor, College of Health and Medicine, Australian National University, and Canberra Rheumatology, and Department of Rheumatology, Canberra Hospital. Address correspondence to A. Kelly, 40 Marcus Clarke St., Canberra City, ACT 2601, Australia. Email: ayano.kelly@anu.edu.au. Accepted for publication December 6, 2019.
Daniel Sumpton
From the College of Health and Medicine, Australian National University, Canberra, ACT; Canberra Rheumatology, Canberra, ACT; Centre for Kidney Research, The Children’s Hospital at Westmead, Sydney, NSW; Sydney School of Public Health, The University of Sydney, Sydney, NSW, Australia; Department of Medicine, McGill University and Research Institute, McGill University Health Centres, Montreal, Quebec, Canada; Division of Rheumatology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA; Department of Pharmacy, Radboud University Medical Centre, Nijmegen, the Netherlands; Musculoskeletal Statistics Unit, the Parker Institute, Copenhagen University Hospital, Copenhagen, Denmark; Research Unit of Rheumatology, Department of Clinical Research, University of Southern Denmark, Odense University Hospital, Odense, Denmark; Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver; Arthritis Research Canada, Richmond, British Columbia, Canada; OMERACT Patient Research Partner, the Netherlands; Clear Vision Consulting, and OMERACT Patient Research Partner, Canberra, ACT; Discipline of Optometry, University of Canberra, Canberra, ACT; Dragon Claw Website, and OMERACT Patient Research Partner, Sydney, NSW; Institute of Bone and Joint Research, Kolling Institute of Medical Research, Sydney, NSW; Department of Rheumatology, Royal North Shore Hospital, Sydney, NSW; Northern Clinical School, The University of Sydney, Sydney, NSW, Australia; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada; Department of Psychology, Health and Technology, University of Twente, Enschede, the Netherlands, and OMERACT Patient Research Partner; Medicine Service, VA Medical Center, Birmingham, Alabama; Department of Medicine, School of Medicine, and Division of Epidemiology, School of Public Health, University of Alabama, Birmingham, Alabama, USA; University of Alabama, Birmingham, Alabama, USA; Department of Rheumatology, Concord Hospital, Sydney, NSW, Australia; The Children’s Hospital of Eastern Ontario Research Institute, Ottawa; Department of Pediatrics and School of Rehabilitation Sciences, and Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada; Department of Pharmacy, Sint Maartenskliniek, Ubbergen, the Netherlands; Centre for Epidemiology Versus Arthritis, Centre for Musculoskeletal Research, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester; UK National Institute for Health Research (NIHR) Manchester Biomedical Research Centre, Manchester University Hospitals National Health Service (NHS) Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK; Department of Rheumatology, Canberra Hospital, Canberra, ACT, Australia. The work reported in this manuscript was supported by the 2018 Arthritis Australia Project Grant. AK is supported by the Australian Government Research Training Scholarship. SV is supported by Versus Arthritis (grant number 20385) and NIHR Manchester Biomedical Research Centre. RC (The Parker Institute, Copenhagen University Hospital) is supported by a core grant from the Oak Foundation (OCAY-13-309). The funders had no role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript. A. Kelly, MBBS, FRACP, College of Health and Medicine, Australian National University, and Canberra Rheumatology, and Centre for Kidney Research, The Children’s Hospital at Westmead; L. Crimston-Smith, BN, College of Health and Medicine, Australian National University, and Canberra Rheumatology; A. Tong, PhD, Professor, Centre for Kidney Research, The Children’s Hospital at Westmead, and Sydney School of Public Health, The University of Sydney; S.J. Bartlett, PhD, Professor, Department of Medicine, McGill University and Research Institute, McGill University Health Centres, and Division of Rheumatology, Johns Hopkins School of Medicine; C.L. Bekker, PhD, Department of Pharmacy, Radboud University Medical Centre; R. Christensen, Musculoskeletal Statistics Unit, the Parker Institute, Copenhagen University Hospital, and the Research Unit of Rheumatology, Department of Clinical Research, University of Southern Denmark, Odense University Hospital; M.A. De Vera, PhD, Assistant Professor, Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, The University of British Columbia, and Arthritis Research Canada; M. de Wit, PhD, OMERACT Patient Research Partner; V. Evans, PhD, Clear Vision Consulting, and OMERACT Patient Research Partner, and Discipline of Optometry, University of Canberra; M. Gill, BA, Dragon Claw Website, and OMERACT Patient Research Partner; L. March, PhD, Professor, Institute of Bone and Joint Research, Kolling Institute of Medical Research, and the Department of Rheumatology, Royal North Shore Hospital, and the Northern Clinical School, The University of Sydney; K. Manera, MIPH, Centre for Kidney Research, The Children’s Hospital at Westmead, and the Sydney School of Public Health, The University of Sydney; R. Nieuwlaat, PhD, Associate Professor, Department of Health Research Methods, Evidence, and Impact, McMaster University; S. Salmasi, MSc, Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, University of British Columbia, and Arthritis Research Canada; M. Scholte-Voshaar, MSc, Department of Psychology, Health and Technology, University of Twente, and OMERACT Patient Research Partner; J.A. Singh, MD, Professor, Medicine Service, VA Medical Center, and Department of Medicine, School of Medicine, and Division of Epidemiology, School of Public Health, University of Alabama; D. Sumpton, MBBS, FRACP, Centre for Kidney Research, The Children’s Hospital at Westmead, Sydney, and Sydney School of Public Health, The University of Sydney, and Department of Rheumatology, Concord Hospital; K. Toupin-April, PhD, Associate Scientist, The Children’s Hospital of Eastern Ontario Research Institute, and Assistant Professor, the Department of Pediatrics and School of Rehabilitation Sciences, University of Ottawa; P. Tugwell, MD, Professor, Department of Medicine, University of Ottawa; B. van den Bemt, PhD, Assistant Professor, Department of Pharmacy, Radboud University Medical Centre, and Department of Pharmacy, Sint Maartenskliniek; S. Verstappen, PhD, Reader, Centre for Epidemiology Versus Arthritis, Centre for Musculoskeletal Research, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, and NIHR Manchester Biomedical Research Centre, Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre; K. Tymms, MBBS, FRACP, Associate Professor, College of Health and Medicine, Australian National University, and Canberra Rheumatology, and Department of Rheumatology, Canberra Hospital. Address correspondence to A. Kelly, 40 Marcus Clarke St., Canberra City, ACT 2601, Australia. Email: ayano.kelly@anu.edu.au. Accepted for publication December 6, 2019.
Karine Toupin-April
From the College of Health and Medicine, Australian National University, Canberra, ACT; Canberra Rheumatology, Canberra, ACT; Centre for Kidney Research, The Children’s Hospital at Westmead, Sydney, NSW; Sydney School of Public Health, The University of Sydney, Sydney, NSW, Australia; Department of Medicine, McGill University and Research Institute, McGill University Health Centres, Montreal, Quebec, Canada; Division of Rheumatology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA; Department of Pharmacy, Radboud University Medical Centre, Nijmegen, the Netherlands; Musculoskeletal Statistics Unit, the Parker Institute, Copenhagen University Hospital, Copenhagen, Denmark; Research Unit of Rheumatology, Department of Clinical Research, University of Southern Denmark, Odense University Hospital, Odense, Denmark; Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver; Arthritis Research Canada, Richmond, British Columbia, Canada; OMERACT Patient Research Partner, the Netherlands; Clear Vision Consulting, and OMERACT Patient Research Partner, Canberra, ACT; Discipline of Optometry, University of Canberra, Canberra, ACT; Dragon Claw Website, and OMERACT Patient Research Partner, Sydney, NSW; Institute of Bone and Joint Research, Kolling Institute of Medical Research, Sydney, NSW; Department of Rheumatology, Royal North Shore Hospital, Sydney, NSW; Northern Clinical School, The University of Sydney, Sydney, NSW, Australia; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada; Department of Psychology, Health and Technology, University of Twente, Enschede, the Netherlands, and OMERACT Patient Research Partner; Medicine Service, VA Medical Center, Birmingham, Alabama; Department of Medicine, School of Medicine, and Division of Epidemiology, School of Public Health, University of Alabama, Birmingham, Alabama, USA; University of Alabama, Birmingham, Alabama, USA; Department of Rheumatology, Concord Hospital, Sydney, NSW, Australia; The Children’s Hospital of Eastern Ontario Research Institute, Ottawa; Department of Pediatrics and School of Rehabilitation Sciences, and Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada; Department of Pharmacy, Sint Maartenskliniek, Ubbergen, the Netherlands; Centre for Epidemiology Versus Arthritis, Centre for Musculoskeletal Research, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester; UK National Institute for Health Research (NIHR) Manchester Biomedical Research Centre, Manchester University Hospitals National Health Service (NHS) Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK; Department of Rheumatology, Canberra Hospital, Canberra, ACT, Australia. The work reported in this manuscript was supported by the 2018 Arthritis Australia Project Grant. AK is supported by the Australian Government Research Training Scholarship. SV is supported by Versus Arthritis (grant number 20385) and NIHR Manchester Biomedical Research Centre. RC (The Parker Institute, Copenhagen University Hospital) is supported by a core grant from the Oak Foundation (OCAY-13-309). The funders had no role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript. A. Kelly, MBBS, FRACP, College of Health and Medicine, Australian National University, and Canberra Rheumatology, and Centre for Kidney Research, The Children’s Hospital at Westmead; L. Crimston-Smith, BN, College of Health and Medicine, Australian National University, and Canberra Rheumatology; A. Tong, PhD, Professor, Centre for Kidney Research, The Children’s Hospital at Westmead, and Sydney School of Public Health, The University of Sydney; S.J. Bartlett, PhD, Professor, Department of Medicine, McGill University and Research Institute, McGill University Health Centres, and Division of Rheumatology, Johns Hopkins School of Medicine; C.L. Bekker, PhD, Department of Pharmacy, Radboud University Medical Centre; R. Christensen, Musculoskeletal Statistics Unit, the Parker Institute, Copenhagen University Hospital, and the Research Unit of Rheumatology, Department of Clinical Research, University of Southern Denmark, Odense University Hospital; M.A. De Vera, PhD, Assistant Professor, Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, The University of British Columbia, and Arthritis Research Canada; M. de Wit, PhD, OMERACT Patient Research Partner; V. Evans, PhD, Clear Vision Consulting, and OMERACT Patient Research Partner, and Discipline of Optometry, University of Canberra; M. Gill, BA, Dragon Claw Website, and OMERACT Patient Research Partner; L. March, PhD, Professor, Institute of Bone and Joint Research, Kolling Institute of Medical Research, and the Department of Rheumatology, Royal North Shore Hospital, and the Northern Clinical School, The University of Sydney; K. Manera, MIPH, Centre for Kidney Research, The Children’s Hospital at Westmead, and the Sydney School of Public Health, The University of Sydney; R. Nieuwlaat, PhD, Associate Professor, Department of Health Research Methods, Evidence, and Impact, McMaster University; S. Salmasi, MSc, Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, University of British Columbia, and Arthritis Research Canada; M. Scholte-Voshaar, MSc, Department of Psychology, Health and Technology, University of Twente, and OMERACT Patient Research Partner; J.A. Singh, MD, Professor, Medicine Service, VA Medical Center, and Department of Medicine, School of Medicine, and Division of Epidemiology, School of Public Health, University of Alabama; D. Sumpton, MBBS, FRACP, Centre for Kidney Research, The Children’s Hospital at Westmead, Sydney, and Sydney School of Public Health, The University of Sydney, and Department of Rheumatology, Concord Hospital; K. Toupin-April, PhD, Associate Scientist, The Children’s Hospital of Eastern Ontario Research Institute, and Assistant Professor, the Department of Pediatrics and School of Rehabilitation Sciences, University of Ottawa; P. Tugwell, MD, Professor, Department of Medicine, University of Ottawa; B. van den Bemt, PhD, Assistant Professor, Department of Pharmacy, Radboud University Medical Centre, and Department of Pharmacy, Sint Maartenskliniek; S. Verstappen, PhD, Reader, Centre for Epidemiology Versus Arthritis, Centre for Musculoskeletal Research, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, and NIHR Manchester Biomedical Research Centre, Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre; K. Tymms, MBBS, FRACP, Associate Professor, College of Health and Medicine, Australian National University, and Canberra Rheumatology, and Department of Rheumatology, Canberra Hospital. Address correspondence to A. Kelly, 40 Marcus Clarke St., Canberra City, ACT 2601, Australia. Email: ayano.kelly@anu.edu.au. Accepted for publication December 6, 2019.
Peter Tugwell
From the College of Health and Medicine, Australian National University, Canberra, ACT; Canberra Rheumatology, Canberra, ACT; Centre for Kidney Research, The Children’s Hospital at Westmead, Sydney, NSW; Sydney School of Public Health, The University of Sydney, Sydney, NSW, Australia; Department of Medicine, McGill University and Research Institute, McGill University Health Centres, Montreal, Quebec, Canada; Division of Rheumatology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA; Department of Pharmacy, Radboud University Medical Centre, Nijmegen, the Netherlands; Musculoskeletal Statistics Unit, the Parker Institute, Copenhagen University Hospital, Copenhagen, Denmark; Research Unit of Rheumatology, Department of Clinical Research, University of Southern Denmark, Odense University Hospital, Odense, Denmark; Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver; Arthritis Research Canada, Richmond, British Columbia, Canada; OMERACT Patient Research Partner, the Netherlands; Clear Vision Consulting, and OMERACT Patient Research Partner, Canberra, ACT; Discipline of Optometry, University of Canberra, Canberra, ACT; Dragon Claw Website, and OMERACT Patient Research Partner, Sydney, NSW; Institute of Bone and Joint Research, Kolling Institute of Medical Research, Sydney, NSW; Department of Rheumatology, Royal North Shore Hospital, Sydney, NSW; Northern Clinical School, The University of Sydney, Sydney, NSW, Australia; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada; Department of Psychology, Health and Technology, University of Twente, Enschede, the Netherlands, and OMERACT Patient Research Partner; Medicine Service, VA Medical Center, Birmingham, Alabama; Department of Medicine, School of Medicine, and Division of Epidemiology, School of Public Health, University of Alabama, Birmingham, Alabama, USA; University of Alabama, Birmingham, Alabama, USA; Department of Rheumatology, Concord Hospital, Sydney, NSW, Australia; The Children’s Hospital of Eastern Ontario Research Institute, Ottawa; Department of Pediatrics and School of Rehabilitation Sciences, and Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada; Department of Pharmacy, Sint Maartenskliniek, Ubbergen, the Netherlands; Centre for Epidemiology Versus Arthritis, Centre for Musculoskeletal Research, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester; UK National Institute for Health Research (NIHR) Manchester Biomedical Research Centre, Manchester University Hospitals National Health Service (NHS) Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK; Department of Rheumatology, Canberra Hospital, Canberra, ACT, Australia. The work reported in this manuscript was supported by the 2018 Arthritis Australia Project Grant. AK is supported by the Australian Government Research Training Scholarship. SV is supported by Versus Arthritis (grant number 20385) and NIHR Manchester Biomedical Research Centre. RC (The Parker Institute, Copenhagen University Hospital) is supported by a core grant from the Oak Foundation (OCAY-13-309). The funders had no role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript. A. Kelly, MBBS, FRACP, College of Health and Medicine, Australian National University, and Canberra Rheumatology, and Centre for Kidney Research, The Children’s Hospital at Westmead; L. Crimston-Smith, BN, College of Health and Medicine, Australian National University, and Canberra Rheumatology; A. Tong, PhD, Professor, Centre for Kidney Research, The Children’s Hospital at Westmead, and Sydney School of Public Health, The University of Sydney; S.J. Bartlett, PhD, Professor, Department of Medicine, McGill University and Research Institute, McGill University Health Centres, and Division of Rheumatology, Johns Hopkins School of Medicine; C.L. Bekker, PhD, Department of Pharmacy, Radboud University Medical Centre; R. Christensen, Musculoskeletal Statistics Unit, the Parker Institute, Copenhagen University Hospital, and the Research Unit of Rheumatology, Department of Clinical Research, University of Southern Denmark, Odense University Hospital; M.A. De Vera, PhD, Assistant Professor, Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, The University of British Columbia, and Arthritis Research Canada; M. de Wit, PhD, OMERACT Patient Research Partner; V. Evans, PhD, Clear Vision Consulting, and OMERACT Patient Research Partner, and Discipline of Optometry, University of Canberra; M. Gill, BA, Dragon Claw Website, and OMERACT Patient Research Partner; L. March, PhD, Professor, Institute of Bone and Joint Research, Kolling Institute of Medical Research, and the Department of Rheumatology, Royal North Shore Hospital, and the Northern Clinical School, The University of Sydney; K. Manera, MIPH, Centre for Kidney Research, The Children’s Hospital at Westmead, and the Sydney School of Public Health, The University of Sydney; R. Nieuwlaat, PhD, Associate Professor, Department of Health Research Methods, Evidence, and Impact, McMaster University; S. Salmasi, MSc, Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, University of British Columbia, and Arthritis Research Canada; M. Scholte-Voshaar, MSc, Department of Psychology, Health and Technology, University of Twente, and OMERACT Patient Research Partner; J.A. Singh, MD, Professor, Medicine Service, VA Medical Center, and Department of Medicine, School of Medicine, and Division of Epidemiology, School of Public Health, University of Alabama; D. Sumpton, MBBS, FRACP, Centre for Kidney Research, The Children’s Hospital at Westmead, Sydney, and Sydney School of Public Health, The University of Sydney, and Department of Rheumatology, Concord Hospital; K. Toupin-April, PhD, Associate Scientist, The Children’s Hospital of Eastern Ontario Research Institute, and Assistant Professor, the Department of Pediatrics and School of Rehabilitation Sciences, University of Ottawa; P. Tugwell, MD, Professor, Department of Medicine, University of Ottawa; B. van den Bemt, PhD, Assistant Professor, Department of Pharmacy, Radboud University Medical Centre, and Department of Pharmacy, Sint Maartenskliniek; S. Verstappen, PhD, Reader, Centre for Epidemiology Versus Arthritis, Centre for Musculoskeletal Research, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, and NIHR Manchester Biomedical Research Centre, Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre; K. Tymms, MBBS, FRACP, Associate Professor, College of Health and Medicine, Australian National University, and Canberra Rheumatology, and Department of Rheumatology, Canberra Hospital. Address correspondence to A. Kelly, 40 Marcus Clarke St., Canberra City, ACT 2601, Australia. Email: ayano.kelly@anu.edu.au. Accepted for publication December 6, 2019.
Bart van den Bemt
From the College of Health and Medicine, Australian National University, Canberra, ACT; Canberra Rheumatology, Canberra, ACT; Centre for Kidney Research, The Children’s Hospital at Westmead, Sydney, NSW; Sydney School of Public Health, The University of Sydney, Sydney, NSW, Australia; Department of Medicine, McGill University and Research Institute, McGill University Health Centres, Montreal, Quebec, Canada; Division of Rheumatology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA; Department of Pharmacy, Radboud University Medical Centre, Nijmegen, the Netherlands; Musculoskeletal Statistics Unit, the Parker Institute, Copenhagen University Hospital, Copenhagen, Denmark; Research Unit of Rheumatology, Department of Clinical Research, University of Southern Denmark, Odense University Hospital, Odense, Denmark; Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver; Arthritis Research Canada, Richmond, British Columbia, Canada; OMERACT Patient Research Partner, the Netherlands; Clear Vision Consulting, and OMERACT Patient Research Partner, Canberra, ACT; Discipline of Optometry, University of Canberra, Canberra, ACT; Dragon Claw Website, and OMERACT Patient Research Partner, Sydney, NSW; Institute of Bone and Joint Research, Kolling Institute of Medical Research, Sydney, NSW; Department of Rheumatology, Royal North Shore Hospital, Sydney, NSW; Northern Clinical School, The University of Sydney, Sydney, NSW, Australia; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada; Department of Psychology, Health and Technology, University of Twente, Enschede, the Netherlands, and OMERACT Patient Research Partner; Medicine Service, VA Medical Center, Birmingham, Alabama; Department of Medicine, School of Medicine, and Division of Epidemiology, School of Public Health, University of Alabama, Birmingham, Alabama, USA; University of Alabama, Birmingham, Alabama, USA; Department of Rheumatology, Concord Hospital, Sydney, NSW, Australia; The Children’s Hospital of Eastern Ontario Research Institute, Ottawa; Department of Pediatrics and School of Rehabilitation Sciences, and Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada; Department of Pharmacy, Sint Maartenskliniek, Ubbergen, the Netherlands; Centre for Epidemiology Versus Arthritis, Centre for Musculoskeletal Research, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester; UK National Institute for Health Research (NIHR) Manchester Biomedical Research Centre, Manchester University Hospitals National Health Service (NHS) Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK; Department of Rheumatology, Canberra Hospital, Canberra, ACT, Australia. The work reported in this manuscript was supported by the 2018 Arthritis Australia Project Grant. AK is supported by the Australian Government Research Training Scholarship. SV is supported by Versus Arthritis (grant number 20385) and NIHR Manchester Biomedical Research Centre. RC (The Parker Institute, Copenhagen University Hospital) is supported by a core grant from the Oak Foundation (OCAY-13-309). The funders had no role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript. A. Kelly, MBBS, FRACP, College of Health and Medicine, Australian National University, and Canberra Rheumatology, and Centre for Kidney Research, The Children’s Hospital at Westmead; L. Crimston-Smith, BN, College of Health and Medicine, Australian National University, and Canberra Rheumatology; A. Tong, PhD, Professor, Centre for Kidney Research, The Children’s Hospital at Westmead, and Sydney School of Public Health, The University of Sydney; S.J. Bartlett, PhD, Professor, Department of Medicine, McGill University and Research Institute, McGill University Health Centres, and Division of Rheumatology, Johns Hopkins School of Medicine; C.L. Bekker, PhD, Department of Pharmacy, Radboud University Medical Centre; R. Christensen, Musculoskeletal Statistics Unit, the Parker Institute, Copenhagen University Hospital, and the Research Unit of Rheumatology, Department of Clinical Research, University of Southern Denmark, Odense University Hospital; M.A. De Vera, PhD, Assistant Professor, Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, The University of British Columbia, and Arthritis Research Canada; M. de Wit, PhD, OMERACT Patient Research Partner; V. Evans, PhD, Clear Vision Consulting, and OMERACT Patient Research Partner, and Discipline of Optometry, University of Canberra; M. Gill, BA, Dragon Claw Website, and OMERACT Patient Research Partner; L. March, PhD, Professor, Institute of Bone and Joint Research, Kolling Institute of Medical Research, and the Department of Rheumatology, Royal North Shore Hospital, and the Northern Clinical School, The University of Sydney; K. Manera, MIPH, Centre for Kidney Research, The Children’s Hospital at Westmead, and the Sydney School of Public Health, The University of Sydney; R. Nieuwlaat, PhD, Associate Professor, Department of Health Research Methods, Evidence, and Impact, McMaster University; S. Salmasi, MSc, Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, University of British Columbia, and Arthritis Research Canada; M. Scholte-Voshaar, MSc, Department of Psychology, Health and Technology, University of Twente, and OMERACT Patient Research Partner; J.A. Singh, MD, Professor, Medicine Service, VA Medical Center, and Department of Medicine, School of Medicine, and Division of Epidemiology, School of Public Health, University of Alabama; D. Sumpton, MBBS, FRACP, Centre for Kidney Research, The Children’s Hospital at Westmead, Sydney, and Sydney School of Public Health, The University of Sydney, and Department of Rheumatology, Concord Hospital; K. Toupin-April, PhD, Associate Scientist, The Children’s Hospital of Eastern Ontario Research Institute, and Assistant Professor, the Department of Pediatrics and School of Rehabilitation Sciences, University of Ottawa; P. Tugwell, MD, Professor, Department of Medicine, University of Ottawa; B. van den Bemt, PhD, Assistant Professor, Department of Pharmacy, Radboud University Medical Centre, and Department of Pharmacy, Sint Maartenskliniek; S. Verstappen, PhD, Reader, Centre for Epidemiology Versus Arthritis, Centre for Musculoskeletal Research, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, and NIHR Manchester Biomedical Research Centre, Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre; K. Tymms, MBBS, FRACP, Associate Professor, College of Health and Medicine, Australian National University, and Canberra Rheumatology, and Department of Rheumatology, Canberra Hospital. Address correspondence to A. Kelly, 40 Marcus Clarke St., Canberra City, ACT 2601, Australia. Email: ayano.kelly@anu.edu.au. Accepted for publication December 6, 2019.
Suzanne Verstappen
From the College of Health and Medicine, Australian National University, Canberra, ACT; Canberra Rheumatology, Canberra, ACT; Centre for Kidney Research, The Children’s Hospital at Westmead, Sydney, NSW; Sydney School of Public Health, The University of Sydney, Sydney, NSW, Australia; Department of Medicine, McGill University and Research Institute, McGill University Health Centres, Montreal, Quebec, Canada; Division of Rheumatology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA; Department of Pharmacy, Radboud University Medical Centre, Nijmegen, the Netherlands; Musculoskeletal Statistics Unit, the Parker Institute, Copenhagen University Hospital, Copenhagen, Denmark; Research Unit of Rheumatology, Department of Clinical Research, University of Southern Denmark, Odense University Hospital, Odense, Denmark; Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver; Arthritis Research Canada, Richmond, British Columbia, Canada; OMERACT Patient Research Partner, the Netherlands; Clear Vision Consulting, and OMERACT Patient Research Partner, Canberra, ACT; Discipline of Optometry, University of Canberra, Canberra, ACT; Dragon Claw Website, and OMERACT Patient Research Partner, Sydney, NSW; Institute of Bone and Joint Research, Kolling Institute of Medical Research, Sydney, NSW; Department of Rheumatology, Royal North Shore Hospital, Sydney, NSW; Northern Clinical School, The University of Sydney, Sydney, NSW, Australia; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada; Department of Psychology, Health and Technology, University of Twente, Enschede, the Netherlands, and OMERACT Patient Research Partner; Medicine Service, VA Medical Center, Birmingham, Alabama; Department of Medicine, School of Medicine, and Division of Epidemiology, School of Public Health, University of Alabama, Birmingham, Alabama, USA; University of Alabama, Birmingham, Alabama, USA; Department of Rheumatology, Concord Hospital, Sydney, NSW, Australia; The Children’s Hospital of Eastern Ontario Research Institute, Ottawa; Department of Pediatrics and School of Rehabilitation Sciences, and Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada; Department of Pharmacy, Sint Maartenskliniek, Ubbergen, the Netherlands; Centre for Epidemiology Versus Arthritis, Centre for Musculoskeletal Research, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester; UK National Institute for Health Research (NIHR) Manchester Biomedical Research Centre, Manchester University Hospitals National Health Service (NHS) Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK; Department of Rheumatology, Canberra Hospital, Canberra, ACT, Australia. The work reported in this manuscript was supported by the 2018 Arthritis Australia Project Grant. AK is supported by the Australian Government Research Training Scholarship. SV is supported by Versus Arthritis (grant number 20385) and NIHR Manchester Biomedical Research Centre. RC (The Parker Institute, Copenhagen University Hospital) is supported by a core grant from the Oak Foundation (OCAY-13-309). The funders had no role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript. A. Kelly, MBBS, FRACP, College of Health and Medicine, Australian National University, and Canberra Rheumatology, and Centre for Kidney Research, The Children’s Hospital at Westmead; L. Crimston-Smith, BN, College of Health and Medicine, Australian National University, and Canberra Rheumatology; A. Tong, PhD, Professor, Centre for Kidney Research, The Children’s Hospital at Westmead, and Sydney School of Public Health, The University of Sydney; S.J. Bartlett, PhD, Professor, Department of Medicine, McGill University and Research Institute, McGill University Health Centres, and Division of Rheumatology, Johns Hopkins School of Medicine; C.L. Bekker, PhD, Department of Pharmacy, Radboud University Medical Centre; R. Christensen, Musculoskeletal Statistics Unit, the Parker Institute, Copenhagen University Hospital, and the Research Unit of Rheumatology, Department of Clinical Research, University of Southern Denmark, Odense University Hospital; M.A. De Vera, PhD, Assistant Professor, Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, The University of British Columbia, and Arthritis Research Canada; M. de Wit, PhD, OMERACT Patient Research Partner; V. Evans, PhD, Clear Vision Consulting, and OMERACT Patient Research Partner, and Discipline of Optometry, University of Canberra; M. Gill, BA, Dragon Claw Website, and OMERACT Patient Research Partner; L. March, PhD, Professor, Institute of Bone and Joint Research, Kolling Institute of Medical Research, and the Department of Rheumatology, Royal North Shore Hospital, and the Northern Clinical School, The University of Sydney; K. Manera, MIPH, Centre for Kidney Research, The Children’s Hospital at Westmead, and the Sydney School of Public Health, The University of Sydney; R. Nieuwlaat, PhD, Associate Professor, Department of Health Research Methods, Evidence, and Impact, McMaster University; S. Salmasi, MSc, Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, University of British Columbia, and Arthritis Research Canada; M. Scholte-Voshaar, MSc, Department of Psychology, Health and Technology, University of Twente, and OMERACT Patient Research Partner; J.A. Singh, MD, Professor, Medicine Service, VA Medical Center, and Department of Medicine, School of Medicine, and Division of Epidemiology, School of Public Health, University of Alabama; D. Sumpton, MBBS, FRACP, Centre for Kidney Research, The Children’s Hospital at Westmead, Sydney, and Sydney School of Public Health, The University of Sydney, and Department of Rheumatology, Concord Hospital; K. Toupin-April, PhD, Associate Scientist, The Children’s Hospital of Eastern Ontario Research Institute, and Assistant Professor, the Department of Pediatrics and School of Rehabilitation Sciences, University of Ottawa; P. Tugwell, MD, Professor, Department of Medicine, University of Ottawa; B. van den Bemt, PhD, Assistant Professor, Department of Pharmacy, Radboud University Medical Centre, and Department of Pharmacy, Sint Maartenskliniek; S. Verstappen, PhD, Reader, Centre for Epidemiology Versus Arthritis, Centre for Musculoskeletal Research, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, and NIHR Manchester Biomedical Research Centre, Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre; K. Tymms, MBBS, FRACP, Associate Professor, College of Health and Medicine, Australian National University, and Canberra Rheumatology, and Department of Rheumatology, Canberra Hospital. Address correspondence to A. Kelly, 40 Marcus Clarke St., Canberra City, ACT 2601, Australia. Email: ayano.kelly@anu.edu.au. Accepted for publication December 6, 2019.
Kathleen Tymms
From the College of Health and Medicine, Australian National University, Canberra, ACT; Canberra Rheumatology, Canberra, ACT; Centre for Kidney Research, The Children’s Hospital at Westmead, Sydney, NSW; Sydney School of Public Health, The University of Sydney, Sydney, NSW, Australia; Department of Medicine, McGill University and Research Institute, McGill University Health Centres, Montreal, Quebec, Canada; Division of Rheumatology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA; Department of Pharmacy, Radboud University Medical Centre, Nijmegen, the Netherlands; Musculoskeletal Statistics Unit, the Parker Institute, Copenhagen University Hospital, Copenhagen, Denmark; Research Unit of Rheumatology, Department of Clinical Research, University of Southern Denmark, Odense University Hospital, Odense, Denmark; Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver; Arthritis Research Canada, Richmond, British Columbia, Canada; OMERACT Patient Research Partner, the Netherlands; Clear Vision Consulting, and OMERACT Patient Research Partner, Canberra, ACT; Discipline of Optometry, University of Canberra, Canberra, ACT; Dragon Claw Website, and OMERACT Patient Research Partner, Sydney, NSW; Institute of Bone and Joint Research, Kolling Institute of Medical Research, Sydney, NSW; Department of Rheumatology, Royal North Shore Hospital, Sydney, NSW; Northern Clinical School, The University of Sydney, Sydney, NSW, Australia; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada; Department of Psychology, Health and Technology, University of Twente, Enschede, the Netherlands, and OMERACT Patient Research Partner; Medicine Service, VA Medical Center, Birmingham, Alabama; Department of Medicine, School of Medicine, and Division of Epidemiology, School of Public Health, University of Alabama, Birmingham, Alabama, USA; University of Alabama, Birmingham, Alabama, USA; Department of Rheumatology, Concord Hospital, Sydney, NSW, Australia; The Children’s Hospital of Eastern Ontario Research Institute, Ottawa; Department of Pediatrics and School of Rehabilitation Sciences, and Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada; Department of Pharmacy, Sint Maartenskliniek, Ubbergen, the Netherlands; Centre for Epidemiology Versus Arthritis, Centre for Musculoskeletal Research, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester; UK National Institute for Health Research (NIHR) Manchester Biomedical Research Centre, Manchester University Hospitals National Health Service (NHS) Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK; Department of Rheumatology, Canberra Hospital, Canberra, ACT, Australia. The work reported in this manuscript was supported by the 2018 Arthritis Australia Project Grant. AK is supported by the Australian Government Research Training Scholarship. SV is supported by Versus Arthritis (grant number 20385) and NIHR Manchester Biomedical Research Centre. RC (The Parker Institute, Copenhagen University Hospital) is supported by a core grant from the Oak Foundation (OCAY-13-309). The funders had no role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript. A. Kelly, MBBS, FRACP, College of Health and Medicine, Australian National University, and Canberra Rheumatology, and Centre for Kidney Research, The Children’s Hospital at Westmead; L. Crimston-Smith, BN, College of Health and Medicine, Australian National University, and Canberra Rheumatology; A. Tong, PhD, Professor, Centre for Kidney Research, The Children’s Hospital at Westmead, and Sydney School of Public Health, The University of Sydney; S.J. Bartlett, PhD, Professor, Department of Medicine, McGill University and Research Institute, McGill University Health Centres, and Division of Rheumatology, Johns Hopkins School of Medicine; C.L. Bekker, PhD, Department of Pharmacy, Radboud University Medical Centre; R. Christensen, Musculoskeletal Statistics Unit, the Parker Institute, Copenhagen University Hospital, and the Research Unit of Rheumatology, Department of Clinical Research, University of Southern Denmark, Odense University Hospital; M.A. De Vera, PhD, Assistant Professor, Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, The University of British Columbia, and Arthritis Research Canada; M. de Wit, PhD, OMERACT Patient Research Partner; V. Evans, PhD, Clear Vision Consulting, and OMERACT Patient Research Partner, and Discipline of Optometry, University of Canberra; M. Gill, BA, Dragon Claw Website, and OMERACT Patient Research Partner; L. March, PhD, Professor, Institute of Bone and Joint Research, Kolling Institute of Medical Research, and the Department of Rheumatology, Royal North Shore Hospital, and the Northern Clinical School, The University of Sydney; K. Manera, MIPH, Centre for Kidney Research, The Children’s Hospital at Westmead, and the Sydney School of Public Health, The University of Sydney; R. Nieuwlaat, PhD, Associate Professor, Department of Health Research Methods, Evidence, and Impact, McMaster University; S. Salmasi, MSc, Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, University of British Columbia, and Arthritis Research Canada; M. Scholte-Voshaar, MSc, Department of Psychology, Health and Technology, University of Twente, and OMERACT Patient Research Partner; J.A. Singh, MD, Professor, Medicine Service, VA Medical Center, and Department of Medicine, School of Medicine, and Division of Epidemiology, School of Public Health, University of Alabama; D. Sumpton, MBBS, FRACP, Centre for Kidney Research, The Children’s Hospital at Westmead, Sydney, and Sydney School of Public Health, The University of Sydney, and Department of Rheumatology, Concord Hospital; K. Toupin-April, PhD, Associate Scientist, The Children’s Hospital of Eastern Ontario Research Institute, and Assistant Professor, the Department of Pediatrics and School of Rehabilitation Sciences, University of Ottawa; P. Tugwell, MD, Professor, Department of Medicine, University of Ottawa; B. van den Bemt, PhD, Assistant Professor, Department of Pharmacy, Radboud University Medical Centre, and Department of Pharmacy, Sint Maartenskliniek; S. Verstappen, PhD, Reader, Centre for Epidemiology Versus Arthritis, Centre for Musculoskeletal Research, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, and NIHR Manchester Biomedical Research Centre, Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre; K. Tymms, MBBS, FRACP, Associate Professor, College of Health and Medicine, Australian National University, and Canberra Rheumatology, and Department of Rheumatology, Canberra Hospital. Address correspondence to A. Kelly, 40 Marcus Clarke St., Canberra City, ACT 2601, Australia. Email: ayano.kelly@anu.edu.au. Accepted for publication December 6, 2019.
In this issue
The Journal of Rheumatology
Vol. 51, Issue 4
1 Apr 2024
Scope of Outcomes in Trials and Observational Studies of Interventions Targeting Medication Adherence in Rheumatic Conditions: A Systematic Review
Ayano Kelly, Luke Crimston-Smith, Allison Tong, Susan J. Bartlett, Charlotte L. Bekker, Robin Christensen, Mary A. De Vera, Maarten de Wit, Vicki Evans, Michael Gill, Lyn March, Karine Manera, Robby Nieuwlaat, Shahrzad Salmasi, Marieke Scholte-Voshaar, Jasvinder A. Singh, Daniel Sumpton, Karine Toupin-April, Peter Tugwell, Bart van den Bemt, Suzanne Verstappen, Kathleen Tymms
The Journal of Rheumatology Dec 2019, jrheum.190726; DOI: 10.3899/jrheum.190726
Scope of Outcomes in Trials and Observational Studies of Interventions Targeting Medication Adherence in Rheumatic Conditions: A Systematic Review
Ayano Kelly, Luke Crimston-Smith, Allison Tong, Susan J. Bartlett, Charlotte L. Bekker, Robin Christensen, Mary A. De Vera, Maarten de Wit, Vicki Evans, Michael Gill, Lyn March, Karine Manera, Robby Nieuwlaat, Shahrzad Salmasi, Marieke Scholte-Voshaar, Jasvinder A. Singh, Daniel Sumpton, Karine Toupin-April, Peter Tugwell, Bart van den Bemt, Suzanne Verstappen, Kathleen Tymms
The Journal of Rheumatology Dec 2019, jrheum.190726; DOI: 10.3899/jrheum.190726