Research ArticleAccepted Article
Ixekizumab Improves Functioning and Health in the Treatment of Radiographic Axial Spondyloarthritis: Week 52 Results from 2 pivotal studies
Uta Kiltz, James Cheng-Chung Wei, Désirée van der Heijde, Filip van den Bosch, Jessica A. Walsh, Annelies Boonen, Lianne S. Gensler, Theresa Hunter, Hilde Carlier, Yan Dong, Xiaoqi Li, Rebecca Bolce, Vibeke Strand and Juergen Braun
The Journal of Rheumatology July 2020, jrheum.200093; DOI: https://doi.org/10.3899/jrheum.200093
Uta Kiltz
Rheumazentrum Ruhrgebiet, Herne Germany; Ruhr-University Bochum, Bochum, Germany; Institute of Medicine, Chung Shan Medical University; Graduate Institute of Integrated Medicine, China Medical University, Taichung, Taiwan; Leiden University Medical Center, Leiden, the Netherlands; Department of Internal Medicine and Pediatrics, Ghent University, VIB Center for Inflammation Research, Ghent, Belgium; University of Utah School of Medicine and Salt Lake City Veterans Affairs Medical Center, Salt Lake City, UT, USA; Rheumatology, Maastricht University Medical Center, Maastricht, the Netherlands; Care and Public Health Research Institute, Maastricht University, Maastricht, the Netherlands; University of California San Francisco, San Francisco, CA, USA; Eli Lilly and Company, Indianapolis, IN, USA; Stanford University School of Medicine, Palo Alto, CA, USA. Address correspondence to Uta Kiltz, Rheumazentrum Ruhrgebiet, Claudiusstrasse 45, 44649 Herne, Germany. uta.kiltz@elisabethgruppe.de
James Cheng-Chung Wei
Rheumazentrum Ruhrgebiet, Herne Germany; Ruhr-University Bochum, Bochum, Germany; Institute of Medicine, Chung Shan Medical University; Graduate Institute of Integrated Medicine, China Medical University, Taichung, Taiwan; Leiden University Medical Center, Leiden, the Netherlands; Department of Internal Medicine and Pediatrics, Ghent University, VIB Center for Inflammation Research, Ghent, Belgium; University of Utah School of Medicine and Salt Lake City Veterans Affairs Medical Center, Salt Lake City, UT, USA; Rheumatology, Maastricht University Medical Center, Maastricht, the Netherlands; Care and Public Health Research Institute, Maastricht University, Maastricht, the Netherlands; University of California San Francisco, San Francisco, CA, USA; Eli Lilly and Company, Indianapolis, IN, USA; Stanford University School of Medicine, Palo Alto, CA, USA. Address correspondence to Uta Kiltz, Rheumazentrum Ruhrgebiet, Claudiusstrasse 45, 44649 Herne, Germany. uta.kiltz@elisabethgruppe.de
Désirée van der Heijde
Rheumazentrum Ruhrgebiet, Herne Germany; Ruhr-University Bochum, Bochum, Germany; Institute of Medicine, Chung Shan Medical University; Graduate Institute of Integrated Medicine, China Medical University, Taichung, Taiwan; Leiden University Medical Center, Leiden, the Netherlands; Department of Internal Medicine and Pediatrics, Ghent University, VIB Center for Inflammation Research, Ghent, Belgium; University of Utah School of Medicine and Salt Lake City Veterans Affairs Medical Center, Salt Lake City, UT, USA; Rheumatology, Maastricht University Medical Center, Maastricht, the Netherlands; Care and Public Health Research Institute, Maastricht University, Maastricht, the Netherlands; University of California San Francisco, San Francisco, CA, USA; Eli Lilly and Company, Indianapolis, IN, USA; Stanford University School of Medicine, Palo Alto, CA, USA. Address correspondence to Uta Kiltz, Rheumazentrum Ruhrgebiet, Claudiusstrasse 45, 44649 Herne, Germany. uta.kiltz@elisabethgruppe.de
Filip van den Bosch
Rheumazentrum Ruhrgebiet, Herne Germany; Ruhr-University Bochum, Bochum, Germany; Institute of Medicine, Chung Shan Medical University; Graduate Institute of Integrated Medicine, China Medical University, Taichung, Taiwan; Leiden University Medical Center, Leiden, the Netherlands; Department of Internal Medicine and Pediatrics, Ghent University, VIB Center for Inflammation Research, Ghent, Belgium; University of Utah School of Medicine and Salt Lake City Veterans Affairs Medical Center, Salt Lake City, UT, USA; Rheumatology, Maastricht University Medical Center, Maastricht, the Netherlands; Care and Public Health Research Institute, Maastricht University, Maastricht, the Netherlands; University of California San Francisco, San Francisco, CA, USA; Eli Lilly and Company, Indianapolis, IN, USA; Stanford University School of Medicine, Palo Alto, CA, USA. Address correspondence to Uta Kiltz, Rheumazentrum Ruhrgebiet, Claudiusstrasse 45, 44649 Herne, Germany. uta.kiltz@elisabethgruppe.de
Jessica A. Walsh
Rheumazentrum Ruhrgebiet, Herne Germany; Ruhr-University Bochum, Bochum, Germany; Institute of Medicine, Chung Shan Medical University; Graduate Institute of Integrated Medicine, China Medical University, Taichung, Taiwan; Leiden University Medical Center, Leiden, the Netherlands; Department of Internal Medicine and Pediatrics, Ghent University, VIB Center for Inflammation Research, Ghent, Belgium; University of Utah School of Medicine and Salt Lake City Veterans Affairs Medical Center, Salt Lake City, UT, USA; Rheumatology, Maastricht University Medical Center, Maastricht, the Netherlands; Care and Public Health Research Institute, Maastricht University, Maastricht, the Netherlands; University of California San Francisco, San Francisco, CA, USA; Eli Lilly and Company, Indianapolis, IN, USA; Stanford University School of Medicine, Palo Alto, CA, USA. Address correspondence to Uta Kiltz, Rheumazentrum Ruhrgebiet, Claudiusstrasse 45, 44649 Herne, Germany. uta.kiltz@elisabethgruppe.de
Annelies Boonen
Rheumazentrum Ruhrgebiet, Herne Germany; Ruhr-University Bochum, Bochum, Germany; Institute of Medicine, Chung Shan Medical University; Graduate Institute of Integrated Medicine, China Medical University, Taichung, Taiwan; Leiden University Medical Center, Leiden, the Netherlands; Department of Internal Medicine and Pediatrics, Ghent University, VIB Center for Inflammation Research, Ghent, Belgium; University of Utah School of Medicine and Salt Lake City Veterans Affairs Medical Center, Salt Lake City, UT, USA; Rheumatology, Maastricht University Medical Center, Maastricht, the Netherlands; Care and Public Health Research Institute, Maastricht University, Maastricht, the Netherlands; University of California San Francisco, San Francisco, CA, USA; Eli Lilly and Company, Indianapolis, IN, USA; Stanford University School of Medicine, Palo Alto, CA, USA. Address correspondence to Uta Kiltz, Rheumazentrum Ruhrgebiet, Claudiusstrasse 45, 44649 Herne, Germany. uta.kiltz@elisabethgruppe.de
Lianne S. Gensler
Rheumazentrum Ruhrgebiet, Herne Germany; Ruhr-University Bochum, Bochum, Germany; Institute of Medicine, Chung Shan Medical University; Graduate Institute of Integrated Medicine, China Medical University, Taichung, Taiwan; Leiden University Medical Center, Leiden, the Netherlands; Department of Internal Medicine and Pediatrics, Ghent University, VIB Center for Inflammation Research, Ghent, Belgium; University of Utah School of Medicine and Salt Lake City Veterans Affairs Medical Center, Salt Lake City, UT, USA; Rheumatology, Maastricht University Medical Center, Maastricht, the Netherlands; Care and Public Health Research Institute, Maastricht University, Maastricht, the Netherlands; University of California San Francisco, San Francisco, CA, USA; Eli Lilly and Company, Indianapolis, IN, USA; Stanford University School of Medicine, Palo Alto, CA, USA. Address correspondence to Uta Kiltz, Rheumazentrum Ruhrgebiet, Claudiusstrasse 45, 44649 Herne, Germany. uta.kiltz@elisabethgruppe.de
Theresa Hunter
Rheumazentrum Ruhrgebiet, Herne Germany; Ruhr-University Bochum, Bochum, Germany; Institute of Medicine, Chung Shan Medical University; Graduate Institute of Integrated Medicine, China Medical University, Taichung, Taiwan; Leiden University Medical Center, Leiden, the Netherlands; Department of Internal Medicine and Pediatrics, Ghent University, VIB Center for Inflammation Research, Ghent, Belgium; University of Utah School of Medicine and Salt Lake City Veterans Affairs Medical Center, Salt Lake City, UT, USA; Rheumatology, Maastricht University Medical Center, Maastricht, the Netherlands; Care and Public Health Research Institute, Maastricht University, Maastricht, the Netherlands; University of California San Francisco, San Francisco, CA, USA; Eli Lilly and Company, Indianapolis, IN, USA; Stanford University School of Medicine, Palo Alto, CA, USA. Address correspondence to Uta Kiltz, Rheumazentrum Ruhrgebiet, Claudiusstrasse 45, 44649 Herne, Germany. uta.kiltz@elisabethgruppe.de
Hilde Carlier
Rheumazentrum Ruhrgebiet, Herne Germany; Ruhr-University Bochum, Bochum, Germany; Institute of Medicine, Chung Shan Medical University; Graduate Institute of Integrated Medicine, China Medical University, Taichung, Taiwan; Leiden University Medical Center, Leiden, the Netherlands; Department of Internal Medicine and Pediatrics, Ghent University, VIB Center for Inflammation Research, Ghent, Belgium; University of Utah School of Medicine and Salt Lake City Veterans Affairs Medical Center, Salt Lake City, UT, USA; Rheumatology, Maastricht University Medical Center, Maastricht, the Netherlands; Care and Public Health Research Institute, Maastricht University, Maastricht, the Netherlands; University of California San Francisco, San Francisco, CA, USA; Eli Lilly and Company, Indianapolis, IN, USA; Stanford University School of Medicine, Palo Alto, CA, USA. Address correspondence to Uta Kiltz, Rheumazentrum Ruhrgebiet, Claudiusstrasse 45, 44649 Herne, Germany. uta.kiltz@elisabethgruppe.de
Yan Dong
Rheumazentrum Ruhrgebiet, Herne Germany; Ruhr-University Bochum, Bochum, Germany; Institute of Medicine, Chung Shan Medical University; Graduate Institute of Integrated Medicine, China Medical University, Taichung, Taiwan; Leiden University Medical Center, Leiden, the Netherlands; Department of Internal Medicine and Pediatrics, Ghent University, VIB Center for Inflammation Research, Ghent, Belgium; University of Utah School of Medicine and Salt Lake City Veterans Affairs Medical Center, Salt Lake City, UT, USA; Rheumatology, Maastricht University Medical Center, Maastricht, the Netherlands; Care and Public Health Research Institute, Maastricht University, Maastricht, the Netherlands; University of California San Francisco, San Francisco, CA, USA; Eli Lilly and Company, Indianapolis, IN, USA; Stanford University School of Medicine, Palo Alto, CA, USA. Address correspondence to Uta Kiltz, Rheumazentrum Ruhrgebiet, Claudiusstrasse 45, 44649 Herne, Germany. uta.kiltz@elisabethgruppe.de
Xiaoqi Li
Rheumazentrum Ruhrgebiet, Herne Germany; Ruhr-University Bochum, Bochum, Germany; Institute of Medicine, Chung Shan Medical University; Graduate Institute of Integrated Medicine, China Medical University, Taichung, Taiwan; Leiden University Medical Center, Leiden, the Netherlands; Department of Internal Medicine and Pediatrics, Ghent University, VIB Center for Inflammation Research, Ghent, Belgium; University of Utah School of Medicine and Salt Lake City Veterans Affairs Medical Center, Salt Lake City, UT, USA; Rheumatology, Maastricht University Medical Center, Maastricht, the Netherlands; Care and Public Health Research Institute, Maastricht University, Maastricht, the Netherlands; University of California San Francisco, San Francisco, CA, USA; Eli Lilly and Company, Indianapolis, IN, USA; Stanford University School of Medicine, Palo Alto, CA, USA. Address correspondence to Uta Kiltz, Rheumazentrum Ruhrgebiet, Claudiusstrasse 45, 44649 Herne, Germany. uta.kiltz@elisabethgruppe.de
Rebecca Bolce
Rheumazentrum Ruhrgebiet, Herne Germany; Ruhr-University Bochum, Bochum, Germany; Institute of Medicine, Chung Shan Medical University; Graduate Institute of Integrated Medicine, China Medical University, Taichung, Taiwan; Leiden University Medical Center, Leiden, the Netherlands; Department of Internal Medicine and Pediatrics, Ghent University, VIB Center for Inflammation Research, Ghent, Belgium; University of Utah School of Medicine and Salt Lake City Veterans Affairs Medical Center, Salt Lake City, UT, USA; Rheumatology, Maastricht University Medical Center, Maastricht, the Netherlands; Care and Public Health Research Institute, Maastricht University, Maastricht, the Netherlands; University of California San Francisco, San Francisco, CA, USA; Eli Lilly and Company, Indianapolis, IN, USA; Stanford University School of Medicine, Palo Alto, CA, USA. Address correspondence to Uta Kiltz, Rheumazentrum Ruhrgebiet, Claudiusstrasse 45, 44649 Herne, Germany. uta.kiltz@elisabethgruppe.de
Vibeke Strand
Rheumazentrum Ruhrgebiet, Herne Germany; Ruhr-University Bochum, Bochum, Germany; Institute of Medicine, Chung Shan Medical University; Graduate Institute of Integrated Medicine, China Medical University, Taichung, Taiwan; Leiden University Medical Center, Leiden, the Netherlands; Department of Internal Medicine and Pediatrics, Ghent University, VIB Center for Inflammation Research, Ghent, Belgium; University of Utah School of Medicine and Salt Lake City Veterans Affairs Medical Center, Salt Lake City, UT, USA; Rheumatology, Maastricht University Medical Center, Maastricht, the Netherlands; Care and Public Health Research Institute, Maastricht University, Maastricht, the Netherlands; University of California San Francisco, San Francisco, CA, USA; Eli Lilly and Company, Indianapolis, IN, USA; Stanford University School of Medicine, Palo Alto, CA, USA. Address correspondence to Uta Kiltz, Rheumazentrum Ruhrgebiet, Claudiusstrasse 45, 44649 Herne, Germany. uta.kiltz@elisabethgruppe.de
Juergen Braun
Rheumazentrum Ruhrgebiet, Herne Germany; Ruhr-University Bochum, Bochum, Germany; Institute of Medicine, Chung Shan Medical University; Graduate Institute of Integrated Medicine, China Medical University, Taichung, Taiwan; Leiden University Medical Center, Leiden, the Netherlands; Department of Internal Medicine and Pediatrics, Ghent University, VIB Center for Inflammation Research, Ghent, Belgium; University of Utah School of Medicine and Salt Lake City Veterans Affairs Medical Center, Salt Lake City, UT, USA; Rheumatology, Maastricht University Medical Center, Maastricht, the Netherlands; Care and Public Health Research Institute, Maastricht University, Maastricht, the Netherlands; University of California San Francisco, San Francisco, CA, USA; Eli Lilly and Company, Indianapolis, IN, USA; Stanford University School of Medicine, Palo Alto, CA, USA. Address correspondence to Uta Kiltz, Rheumazentrum Ruhrgebiet, Claudiusstrasse 45, 44649 Herne, Germany. uta.kiltz@elisabethgruppe.de
In this issue
The Journal of Rheumatology
Vol. 51, Issue 4
1 Apr 2024
Accepted manuscript
Ixekizumab Improves Functioning and Health in the Treatment of Radiographic Axial Spondyloarthritis: Week 52 Results from 2 pivotal studies
Uta Kiltz, James Cheng-Chung Wei, Désirée van der Heijde, Filip van den Bosch, Jessica A. Walsh, Annelies Boonen, Lianne S. Gensler, Theresa Hunter, Hilde Carlier, Yan Dong, Xiaoqi Li, Rebecca Bolce, Vibeke Strand, Juergen Braun
The Journal of Rheumatology Jul 2020, jrheum.200093; DOI: 10.3899/jrheum.200093
Accepted manuscript
Ixekizumab Improves Functioning and Health in the Treatment of Radiographic Axial Spondyloarthritis: Week 52 Results from 2 pivotal studies
Uta Kiltz, James Cheng-Chung Wei, Désirée van der Heijde, Filip van den Bosch, Jessica A. Walsh, Annelies Boonen, Lianne S. Gensler, Theresa Hunter, Hilde Carlier, Yan Dong, Xiaoqi Li, Rebecca Bolce, Vibeke Strand, Juergen Braun
The Journal of Rheumatology Jul 2020, jrheum.200093; DOI: 10.3899/jrheum.200093