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Research ArticleAccepted Article

Association between centromere and topoisomerase specific immune responses and the degree of microangiopathy in Systemic Sclerosis

Nina M. van Leeuwen, Corrie M. Wortel, Cynthia M. Fehres, Jaap. A Bakker, Hans. U. Scherer, René E.M Toes, Tom W.J Huizinga and Jeska K. de Vries-Bouwstra
The Journal of Rheumatology June 2020, jrheum.191331; DOI: https://doi.org/10.3899/jrheum.191331
Nina M. van Leeuwen
From the Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands; Department of Clinical Chemistry and Laboratory Medicine, Leiden University Medical Center, Leiden, the Netherlands. Address correspondence to Nina M. van Leeuwen, department of Rheumatology Leiden University Medical Center, C1-R, PO Box 9600, 2300 RC, Leiden, the Netherlands. E-mail: n.m.van_leeuwen@lumc.nl
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Corrie M. Wortel
From the Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands; Department of Clinical Chemistry and Laboratory Medicine, Leiden University Medical Center, Leiden, the Netherlands. Address correspondence to Nina M. van Leeuwen, department of Rheumatology Leiden University Medical Center, C1-R, PO Box 9600, 2300 RC, Leiden, the Netherlands. E-mail: n.m.van_leeuwen@lumc.nl
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Cynthia M. Fehres
From the Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands; Department of Clinical Chemistry and Laboratory Medicine, Leiden University Medical Center, Leiden, the Netherlands. Address correspondence to Nina M. van Leeuwen, department of Rheumatology Leiden University Medical Center, C1-R, PO Box 9600, 2300 RC, Leiden, the Netherlands. E-mail: n.m.van_leeuwen@lumc.nl
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Jaap. A Bakker
From the Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands; Department of Clinical Chemistry and Laboratory Medicine, Leiden University Medical Center, Leiden, the Netherlands. Address correspondence to Nina M. van Leeuwen, department of Rheumatology Leiden University Medical Center, C1-R, PO Box 9600, 2300 RC, Leiden, the Netherlands. E-mail: n.m.van_leeuwen@lumc.nl
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Hans. U. Scherer
From the Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands; Department of Clinical Chemistry and Laboratory Medicine, Leiden University Medical Center, Leiden, the Netherlands. Address correspondence to Nina M. van Leeuwen, department of Rheumatology Leiden University Medical Center, C1-R, PO Box 9600, 2300 RC, Leiden, the Netherlands. E-mail: n.m.van_leeuwen@lumc.nl
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René E.M Toes
From the Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands; Department of Clinical Chemistry and Laboratory Medicine, Leiden University Medical Center, Leiden, the Netherlands. Address correspondence to Nina M. van Leeuwen, department of Rheumatology Leiden University Medical Center, C1-R, PO Box 9600, 2300 RC, Leiden, the Netherlands. E-mail: n.m.van_leeuwen@lumc.nl
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Tom W.J Huizinga
From the Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands; Department of Clinical Chemistry and Laboratory Medicine, Leiden University Medical Center, Leiden, the Netherlands. Address correspondence to Nina M. van Leeuwen, department of Rheumatology Leiden University Medical Center, C1-R, PO Box 9600, 2300 RC, Leiden, the Netherlands. E-mail: n.m.van_leeuwen@lumc.nl
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Jeska K. de Vries-Bouwstra
From the Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands; Department of Clinical Chemistry and Laboratory Medicine, Leiden University Medical Center, Leiden, the Netherlands. Address correspondence to Nina M. van Leeuwen, department of Rheumatology Leiden University Medical Center, C1-R, PO Box 9600, 2300 RC, Leiden, the Netherlands. E-mail: n.m.van_leeuwen@lumc.nl
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Article Information

jrheum.191331
DOI 
https://doi.org/10.3899/jrheum.191331
PubMed 
32482649

Published By 
The Journal of Rheumatology
Print ISSN 
0315-162X
Online ISSN 
1499-2752
History 
  • Published online June 1, 2020.

Article Versions

  • You are currently viewing a Latest version of this article (June 1, 2020 - 04:00).
  • latest version (December 15, 2020 - 04:00).
  • View the most recent version of this article
Copyright & Usage 
© 2020 The Journal of Rheumatology

Author Information

  1. Nina M. van Leeuwen,
  2. Corrie M. Wortel,
  3. Cynthia M. Fehres,
  4. Jaap. A Bakker,
  5. Hans. U. Scherer,
  6. René E.M Toes,
  7. Tom W.J Huizinga and
  8. Jeska K. de Vries-Bouwstra
  1. From the Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands; Department of Clinical Chemistry and Laboratory Medicine, Leiden University Medical Center, Leiden, the Netherlands.
    Address correspondence to Nina M. van Leeuwen, department of Rheumatology Leiden University Medical Center, C1-R, PO Box 9600, 2300 RC, Leiden, the Netherlands. E-mail: n.m.van_leeuwen@lumc.nl

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The Journal of Rheumatology
Vol. 50, Issue 6
1 Jun 2023
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Accepted manuscript
Association between centromere and topoisomerase specific immune responses and the degree of microangiopathy in Systemic Sclerosis
Nina M. van Leeuwen, Corrie M. Wortel, Cynthia M. Fehres, Jaap. A Bakker, Hans. U. Scherer, René E.M Toes, Tom W.J Huizinga, Jeska K. de Vries-Bouwstra
The Journal of Rheumatology Jun 2020, jrheum.191331; DOI: 10.3899/jrheum.191331

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Accepted manuscript
Association between centromere and topoisomerase specific immune responses and the degree of microangiopathy in Systemic Sclerosis
Nina M. van Leeuwen, Corrie M. Wortel, Cynthia M. Fehres, Jaap. A Bakker, Hans. U. Scherer, René E.M Toes, Tom W.J Huizinga, Jeska K. de Vries-Bouwstra
The Journal of Rheumatology Jun 2020, jrheum.191331; DOI: 10.3899/jrheum.191331
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