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LetterAccepted Article
Open Access

Incidence and clinical course of COVID-19 in patients with connective tissue diseases: a descriptive observational analysis

Ennio Giulio Favalli, Elena Agape and Roberto Caporali
The Journal of Rheumatology April 2020, jrheum.200507; DOI: https://doi.org/10.3899/jrheum.200507
Ennio Giulio Favalli
From the Division of Clinical Rheumatology, ASST Gaetano Pini-CTO Institute, Milan, Italy; the Department of Clinical Sciences and Community Health, Research Center for Adult and Pediatric Rheumatic Diseases, Università degli Studi di Milano, Milano, Italy. Address correspondence to Ennio Giulio Favalli, MD, Division of Clinical Rheumatology, ASST Gaetano Pini-CTO Institute, Milan, Via Gaetano Pini, 9, 20122 Milan - Italy. E-mail: enniofavalli@me.com
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Elena Agape
From the Division of Clinical Rheumatology, ASST Gaetano Pini-CTO Institute, Milan, Italy; the Department of Clinical Sciences and Community Health, Research Center for Adult and Pediatric Rheumatic Diseases, Università degli Studi di Milano, Milano, Italy. Address correspondence to Ennio Giulio Favalli, MD, Division of Clinical Rheumatology, ASST Gaetano Pini-CTO Institute, Milan, Via Gaetano Pini, 9, 20122 Milan - Italy. E-mail: enniofavalli@me.com
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Roberto Caporali
From the Division of Clinical Rheumatology, ASST Gaetano Pini-CTO Institute, Milan, Italy; the Department of Clinical Sciences and Community Health, Research Center for Adult and Pediatric Rheumatic Diseases, Università degli Studi di Milano, Milano, Italy. Address correspondence to Ennio Giulio Favalli, MD, Division of Clinical Rheumatology, ASST Gaetano Pini-CTO Institute, Milan, Via Gaetano Pini, 9, 20122 Milan - Italy. E-mail: enniofavalli@me.com
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Abstract

The outbreak of COVID-19 in December 2019 in China has very quickly become a global health emergency with almost two million of infected patients worldwide.[1] Along with the spread of the pandemic, there has been a growing concern about the management of fragile rheumatic patients, for whom there is still very little data available. In particular, subjects affected by connective tissue diseases (CTD) are known to have an increased infectious risk compared to the healthy population due to a general impairment of the immune system intrinsic to the autoimmune disease itself, the iatrogenic effect linked to the use of immunosuppressive drugs, and the high number of comorbidities that often complicate the clinical picture.[2,3]

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The Journal of Rheumatology
Vol. 50, Issue 6
1 Jun 2023
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Accepted manuscript
Incidence and clinical course of COVID-19 in patients with connective tissue diseases: a descriptive observational analysis
Ennio Giulio Favalli, Elena Agape, Roberto Caporali
The Journal of Rheumatology Apr 2020, jrheum.200507; DOI: 10.3899/jrheum.200507

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Accepted manuscript
Incidence and clinical course of COVID-19 in patients with connective tissue diseases: a descriptive observational analysis
Ennio Giulio Favalli, Elena Agape, Roberto Caporali
The Journal of Rheumatology Apr 2020, jrheum.200507; DOI: 10.3899/jrheum.200507
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