Longterm Outcomes of Temporomandibular Joints in Juvenile Idiopathic Arthritis: 17 Years of Followup of a Nordic Juvenile Idiopathic Arthritis Cohort

From the Department of Pediatrics, Aarhus University Hospital; Section of Orthodontics, Aarhus University; Section of Oral Radiology, Department of Dentistry and Oral Health, Aarhus University, Aarhus, Denmark; Department of Pediatrics, University Hospital of North Norway, Tromsø; Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø; Department of Otorhinolaryngology and Department and Division of Oral and Maxillofacial Surgery, University Hospital North Norway and Public Dental Service Competence Center of North Norway, Tromsø; Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology (NTNU), Trondheim; Department of Pediatrics, Levanger Hospital, Nord-Trøndelag Hospital Trust, Levanger; Department of Pediatrics, St. Olavs Hospital, Trondheim; Department of Oral and Craniomaxillofacial Surgery, St. Olavs Hospital, Trondheim, Norway; Department of Pediatrics, Ryhov County Hospital, Jönköping; Department of Women’s and Children’s Health, Uppsala University, Uppsala; Department of Pediatrics, Sahlgrenska Academy, University of Gothenburg, Gothenburg; Department of Oral and Maxillofacial Surgery/Stomatognathic Physiology, The Institute for Postgraduate Dental Education, Jönköping, Sweden; Hospital for Children and Adolescents, University of Helsinki, Helsinki; Orthodontics, Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital, Helsinki, Finland; Department of Pediatrics, Copenhagen University Hospital, Copenhagen; Department of Pediatric Dentistry and Clinical Genetics, University of Copenhagen, Copenhagen; Department of Oral and Maxillofacial Surgery, Aarhus University Hospital, Aarhus, Denmark. M. Glerup, MD, Department of Pediatrics, Aarhus University Hospital; P. Stoustrup, Associate Professor, DDS, PhD, Section of Orthodontics, Aarhus University; L.H. Matzen, DDS, PhD, Associate Professor, Section of Oral Radiology, Department of Dentistry and Oral Health, Aarhus University; V. Rypdal, MD, Department of Pediatrics, University Hospital of North Norway, and Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway; E. Nordal, MD, PhD, Department of Pediatrics, University Hospital of North Norway, and Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway; P. Frid, DDS, Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, and Department of Otorhinolaryngology and Department and Division of Oral and Maxillofacial Surgery, University Hospital North Norway and Public Dental Service Competence Center of North Norway; E.D. Arnstad, MD, Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, NTNU, and Department of Pediatrics, Levanger Hospital, Nord-Trøndelag Hospital Trust; M. Rygg, MD, Professor, PhD, Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, NTNU, and Department of Pediatrics, St. Olavs Hospital; O. Thorarensen, DDS, Department of Oral and Craniomaxillofacial Surgery, St. Olavs Hospital; M. Ekelund, MD, Department of Pediatrics, Ryhov County Hospital, and Department of Women’s and Children’s Health, Uppsala University; L. Berntson, MD, PhD, Department of Women’s and Children’s Health, Uppsala University; A. Fasth, MD, PhD, Professor, Department of Pediatrics, Sahlgrenska Academy, University of Gothenburg; H. Nilsson, DDS, PhD, Dr. Odont, Department of Oral and Maxillofacial Surgery/Stomatognathic Physiology, The Institute for Postgraduate Dental Education; S. Peltoniemi, MD, Hospital for Children and Adolescents, University of Helsinki; K. Aalto, MD, PhD, Hospital for Children and Adolescents, University of Helsinki; S. Arte, DDS, PhD, Orthodontics, Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital; P. Toftedal, MD, PhD, Department of Pediatrics, Copenhagen University Hospital; S. Nielsen, MD, Department of Pediatrics, Copenhagen University Hospital; S. Kreiborg, Professor, DDS, PhD, Dr. Odont, Department of Pediatric Dentistry and Clinical Genetics, University of Copenhagen; T. Herlin, Professor, MD, DMSc, Department of Pediatrics, Aarhus University Hospital; T.K. Pedersen, Professor, DDS, PhD, Section of Orthodontics, Aarhus University, and Department of Oral and Maxillofacial Surgery, Aarhus University Hospital. Address correspondence to Dr. M. Glerup, Department of Pediatrics, Aarhus University Hospital, Skejby, Palle Juul-Jensens Blvd. 99, 8200 Aarhus N, Denmark. E-mail: miagleru@rm.dk. Accepted for publication September 3, 2019.

From the Department of Pediatrics, Aarhus University Hospital; Section of Orthodontics, Aarhus University; Section of Oral Radiology, Department of Dentistry and Oral Health, Aarhus University, Aarhus, Denmark; Department of Pediatrics, University Hospital of North Norway, Tromsø; Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø; Department of Otorhinolaryngology and Department and Division of Oral and Maxillofacial Surgery, University Hospital North Norway and Public Dental Service Competence Center of North Norway, Tromsø; Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology (NTNU), Trondheim; Department of Pediatrics, Levanger Hospital, Nord-Trøndelag Hospital Trust, Levanger; Department of Pediatrics, St. Olavs Hospital, Trondheim; Department of Oral and Craniomaxillofacial Surgery, St. Olavs Hospital, Trondheim, Norway; Department of Pediatrics, Ryhov County Hospital, Jönköping; Department of Women’s and Children’s Health, Uppsala University, Uppsala; Department of Pediatrics, Sahlgrenska Academy, University of Gothenburg, Gothenburg; Department of Oral and Maxillofacial Surgery/Stomatognathic Physiology, The Institute for Postgraduate Dental Education, Jönköping, Sweden; Hospital for Children and Adolescents, University of Helsinki, Helsinki; Orthodontics, Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital, Helsinki, Finland; Department of Pediatrics, Copenhagen University Hospital, Copenhagen; Department of Pediatric Dentistry and Clinical Genetics, University of Copenhagen, Copenhagen; Department of Oral and Maxillofacial Surgery, Aarhus University Hospital, Aarhus, Denmark. M. Glerup, MD, Department of Pediatrics, Aarhus University Hospital; P. Stoustrup, Associate Professor, DDS, PhD, Section of Orthodontics, Aarhus University; L.H. Matzen, DDS, PhD, Associate Professor, Section of Oral Radiology, Department of Dentistry and Oral Health, Aarhus University; V. Rypdal, MD, Department of Pediatrics, University Hospital of North Norway, and Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway; E. Nordal, MD, PhD, Department of Pediatrics, University Hospital of North Norway, and Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway; P. Frid, DDS, Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, and Department of Otorhinolaryngology and Department and Division of Oral and Maxillofacial Surgery, University Hospital North Norway and Public Dental Service Competence Center of North Norway; E.D. Arnstad, MD, Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, NTNU, and Department of Pediatrics, Levanger Hospital, Nord-Trøndelag Hospital Trust; M. Rygg, MD, Professor, PhD, Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, NTNU, and Department of Pediatrics, St. Olavs Hospital; O. Thorarensen, DDS, Department of Oral and Craniomaxillofacial Surgery, St. Olavs Hospital; M. Ekelund, MD, Department of Pediatrics, Ryhov County Hospital, and Department of Women’s and Children’s Health, Uppsala University; L. Berntson, MD, PhD, Department of Women’s and Children’s Health, Uppsala University; A. Fasth, MD, PhD, Professor, Department of Pediatrics, Sahlgrenska Academy, University of Gothenburg; H. Nilsson, DDS, PhD, Dr. Odont, Department of Oral and Maxillofacial Surgery/Stomatognathic Physiology, The Institute for Postgraduate Dental Education; S. Peltoniemi, MD, Hospital for Children and Adolescents, University of Helsinki; K. Aalto, MD, PhD, Hospital for Children and Adolescents, University of Helsinki; S. Arte, DDS, PhD, Orthodontics, Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital; P. Toftedal, MD, PhD, Department of Pediatrics, Copenhagen University Hospital; S. Nielsen, MD, Department of Pediatrics, Copenhagen University Hospital; S. Kreiborg, Professor, DDS, PhD, Dr. Odont, Department of Pediatric Dentistry and Clinical Genetics, University of Copenhagen; T. Herlin, Professor, MD, DMSc, Department of Pediatrics, Aarhus University Hospital; T.K. Pedersen, Professor, DDS, PhD, Section of Orthodontics, Aarhus University, and Department of Oral and Maxillofacial Surgery, Aarhus University Hospital. Address correspondence to Dr. M. Glerup, Department of Pediatrics, Aarhus University Hospital, Skejby, Palle Juul-Jensens Blvd. 99, 8200 Aarhus N, Denmark. E-mail: miagleru@rm.dk. Accepted for publication September 3, 2019.

From the Department of Pediatrics, Aarhus University Hospital; Section of Orthodontics, Aarhus University; Section of Oral Radiology, Department of Dentistry and Oral Health, Aarhus University, Aarhus, Denmark; Department of Pediatrics, University Hospital of North Norway, Tromsø; Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø; Department of Otorhinolaryngology and Department and Division of Oral and Maxillofacial Surgery, University Hospital North Norway and Public Dental Service Competence Center of North Norway, Tromsø; Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology (NTNU), Trondheim; Department of Pediatrics, Levanger Hospital, Nord-Trøndelag Hospital Trust, Levanger; Department of Pediatrics, St. Olavs Hospital, Trondheim; Department of Oral and Craniomaxillofacial Surgery, St. Olavs Hospital, Trondheim, Norway; Department of Pediatrics, Ryhov County Hospital, Jönköping; Department of Women’s and Children’s Health, Uppsala University, Uppsala; Department of Pediatrics, Sahlgrenska Academy, University of Gothenburg, Gothenburg; Department of Oral and Maxillofacial Surgery/Stomatognathic Physiology, The Institute for Postgraduate Dental Education, Jönköping, Sweden; Hospital for Children and Adolescents, University of Helsinki, Helsinki; Orthodontics, Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital, Helsinki, Finland; Department of Pediatrics, Copenhagen University Hospital, Copenhagen; Department of Pediatric Dentistry and Clinical Genetics, University of Copenhagen, Copenhagen; Department of Oral and Maxillofacial Surgery, Aarhus University Hospital, Aarhus, Denmark. M. Glerup, MD, Department of Pediatrics, Aarhus University Hospital; P. Stoustrup, Associate Professor, DDS, PhD, Section of Orthodontics, Aarhus University; L.H. Matzen, DDS, PhD, Associate Professor, Section of Oral Radiology, Department of Dentistry and Oral Health, Aarhus University; V. Rypdal, MD, Department of Pediatrics, University Hospital of North Norway, and Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway; E. Nordal, MD, PhD, Department of Pediatrics, University Hospital of North Norway, and Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway; P. Frid, DDS, Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, and Department of Otorhinolaryngology and Department and Division of Oral and Maxillofacial Surgery, University Hospital North Norway and Public Dental Service Competence Center of North Norway; E.D. Arnstad, MD, Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, NTNU, and Department of Pediatrics, Levanger Hospital, Nord-Trøndelag Hospital Trust; M. Rygg, MD, Professor, PhD, Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, NTNU, and Department of Pediatrics, St. Olavs Hospital; O. Thorarensen, DDS, Department of Oral and Craniomaxillofacial Surgery, St. Olavs Hospital; M. Ekelund, MD, Department of Pediatrics, Ryhov County Hospital, and Department of Women’s and Children’s Health, Uppsala University; L. Berntson, MD, PhD, Department of Women’s and Children’s Health, Uppsala University; A. Fasth, MD, PhD, Professor, Department of Pediatrics, Sahlgrenska Academy, University of Gothenburg; H. Nilsson, DDS, PhD, Dr. Odont, Department of Oral and Maxillofacial Surgery/Stomatognathic Physiology, The Institute for Postgraduate Dental Education; S. Peltoniemi, MD, Hospital for Children and Adolescents, University of Helsinki; K. Aalto, MD, PhD, Hospital for Children and Adolescents, University of Helsinki; S. Arte, DDS, PhD, Orthodontics, Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital; P. Toftedal, MD, PhD, Department of Pediatrics, Copenhagen University Hospital; S. Nielsen, MD, Department of Pediatrics, Copenhagen University Hospital; S. Kreiborg, Professor, DDS, PhD, Dr. Odont, Department of Pediatric Dentistry and Clinical Genetics, University of Copenhagen; T. Herlin, Professor, MD, DMSc, Department of Pediatrics, Aarhus University Hospital; T.K. Pedersen, Professor, DDS, PhD, Section of Orthodontics, Aarhus University, and Department of Oral and Maxillofacial Surgery, Aarhus University Hospital. Address correspondence to Dr. M. Glerup, Department of Pediatrics, Aarhus University Hospital, Skejby, Palle Juul-Jensens Blvd. 99, 8200 Aarhus N, Denmark. E-mail: miagleru@rm.dk. Accepted for publication September 3, 2019.

From the Department of Pediatrics, Aarhus University Hospital; Section of Orthodontics, Aarhus University; Section of Oral Radiology, Department of Dentistry and Oral Health, Aarhus University, Aarhus, Denmark; Department of Pediatrics, University Hospital of North Norway, Tromsø; Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø; Department of Otorhinolaryngology and Department and Division of Oral and Maxillofacial Surgery, University Hospital North Norway and Public Dental Service Competence Center of North Norway, Tromsø; Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology (NTNU), Trondheim; Department of Pediatrics, Levanger Hospital, Nord-Trøndelag Hospital Trust, Levanger; Department of Pediatrics, St. Olavs Hospital, Trondheim; Department of Oral and Craniomaxillofacial Surgery, St. Olavs Hospital, Trondheim, Norway; Department of Pediatrics, Ryhov County Hospital, Jönköping; Department of Women’s and Children’s Health, Uppsala University, Uppsala; Department of Pediatrics, Sahlgrenska Academy, University of Gothenburg, Gothenburg; Department of Oral and Maxillofacial Surgery/Stomatognathic Physiology, The Institute for Postgraduate Dental Education, Jönköping, Sweden; Hospital for Children and Adolescents, University of Helsinki, Helsinki; Orthodontics, Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital, Helsinki, Finland; Department of Pediatrics, Copenhagen University Hospital, Copenhagen; Department of Pediatric Dentistry and Clinical Genetics, University of Copenhagen, Copenhagen; Department of Oral and Maxillofacial Surgery, Aarhus University Hospital, Aarhus, Denmark. M. Glerup, MD, Department of Pediatrics, Aarhus University Hospital; P. Stoustrup, Associate Professor, DDS, PhD, Section of Orthodontics, Aarhus University; L.H. Matzen, DDS, PhD, Associate Professor, Section of Oral Radiology, Department of Dentistry and Oral Health, Aarhus University; V. Rypdal, MD, Department of Pediatrics, University Hospital of North Norway, and Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway; E. Nordal, MD, PhD, Department of Pediatrics, University Hospital of North Norway, and Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway; P. Frid, DDS, Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, and Department of Otorhinolaryngology and Department and Division of Oral and Maxillofacial Surgery, University Hospital North Norway and Public Dental Service Competence Center of North Norway; E.D. Arnstad, MD, Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, NTNU, and Department of Pediatrics, Levanger Hospital, Nord-Trøndelag Hospital Trust; M. Rygg, MD, Professor, PhD, Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, NTNU, and Department of Pediatrics, St. Olavs Hospital; O. Thorarensen, DDS, Department of Oral and Craniomaxillofacial Surgery, St. Olavs Hospital; M. Ekelund, MD, Department of Pediatrics, Ryhov County Hospital, and Department of Women’s and Children’s Health, Uppsala University; L. Berntson, MD, PhD, Department of Women’s and Children’s Health, Uppsala University; A. Fasth, MD, PhD, Professor, Department of Pediatrics, Sahlgrenska Academy, University of Gothenburg; H. Nilsson, DDS, PhD, Dr. Odont, Department of Oral and Maxillofacial Surgery/Stomatognathic Physiology, The Institute for Postgraduate Dental Education; S. Peltoniemi, MD, Hospital for Children and Adolescents, University of Helsinki; K. Aalto, MD, PhD, Hospital for Children and Adolescents, University of Helsinki; S. Arte, DDS, PhD, Orthodontics, Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital; P. Toftedal, MD, PhD, Department of Pediatrics, Copenhagen University Hospital; S. Nielsen, MD, Department of Pediatrics, Copenhagen University Hospital; S. Kreiborg, Professor, DDS, PhD, Dr. Odont, Department of Pediatric Dentistry and Clinical Genetics, University of Copenhagen; T. Herlin, Professor, MD, DMSc, Department of Pediatrics, Aarhus University Hospital; T.K. Pedersen, Professor, DDS, PhD, Section of Orthodontics, Aarhus University, and Department of Oral and Maxillofacial Surgery, Aarhus University Hospital. Address correspondence to Dr. M. Glerup, Department of Pediatrics, Aarhus University Hospital, Skejby, Palle Juul-Jensens Blvd. 99, 8200 Aarhus N, Denmark. E-mail: miagleru@rm.dk. Accepted for publication September 3, 2019.

From the Department of Pediatrics, Aarhus University Hospital; Section of Orthodontics, Aarhus University; Section of Oral Radiology, Department of Dentistry and Oral Health, Aarhus University, Aarhus, Denmark; Department of Pediatrics, University Hospital of North Norway, Tromsø; Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø; Department of Otorhinolaryngology and Department and Division of Oral and Maxillofacial Surgery, University Hospital North Norway and Public Dental Service Competence Center of North Norway, Tromsø; Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology (NTNU), Trondheim; Department of Pediatrics, Levanger Hospital, Nord-Trøndelag Hospital Trust, Levanger; Department of Pediatrics, St. Olavs Hospital, Trondheim; Department of Oral and Craniomaxillofacial Surgery, St. Olavs Hospital, Trondheim, Norway; Department of Pediatrics, Ryhov County Hospital, Jönköping; Department of Women’s and Children’s Health, Uppsala University, Uppsala; Department of Pediatrics, Sahlgrenska Academy, University of Gothenburg, Gothenburg; Department of Oral and Maxillofacial Surgery/Stomatognathic Physiology, The Institute for Postgraduate Dental Education, Jönköping, Sweden; Hospital for Children and Adolescents, University of Helsinki, Helsinki; Orthodontics, Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital, Helsinki, Finland; Department of Pediatrics, Copenhagen University Hospital, Copenhagen; Department of Pediatric Dentistry and Clinical Genetics, University of Copenhagen, Copenhagen; Department of Oral and Maxillofacial Surgery, Aarhus University Hospital, Aarhus, Denmark. M. Glerup, MD, Department of Pediatrics, Aarhus University Hospital; P. Stoustrup, Associate Professor, DDS, PhD, Section of Orthodontics, Aarhus University; L.H. Matzen, DDS, PhD, Associate Professor, Section of Oral Radiology, Department of Dentistry and Oral Health, Aarhus University; V. Rypdal, MD, Department of Pediatrics, University Hospital of North Norway, and Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway; E. Nordal, MD, PhD, Department of Pediatrics, University Hospital of North Norway, and Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway; P. Frid, DDS, Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, and Department of Otorhinolaryngology and Department and Division of Oral and Maxillofacial Surgery, University Hospital North Norway and Public Dental Service Competence Center of North Norway; E.D. Arnstad, MD, Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, NTNU, and Department of Pediatrics, Levanger Hospital, Nord-Trøndelag Hospital Trust; M. Rygg, MD, Professor, PhD, Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, NTNU, and Department of Pediatrics, St. Olavs Hospital; O. Thorarensen, DDS, Department of Oral and Craniomaxillofacial Surgery, St. Olavs Hospital; M. Ekelund, MD, Department of Pediatrics, Ryhov County Hospital, and Department of Women’s and Children’s Health, Uppsala University; L. Berntson, MD, PhD, Department of Women’s and Children’s Health, Uppsala University; A. Fasth, MD, PhD, Professor, Department of Pediatrics, Sahlgrenska Academy, University of Gothenburg; H. Nilsson, DDS, PhD, Dr. Odont, Department of Oral and Maxillofacial Surgery/Stomatognathic Physiology, The Institute for Postgraduate Dental Education; S. Peltoniemi, MD, Hospital for Children and Adolescents, University of Helsinki; K. Aalto, MD, PhD, Hospital for Children and Adolescents, University of Helsinki; S. Arte, DDS, PhD, Orthodontics, Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital; P. Toftedal, MD, PhD, Department of Pediatrics, Copenhagen University Hospital; S. Nielsen, MD, Department of Pediatrics, Copenhagen University Hospital; S. Kreiborg, Professor, DDS, PhD, Dr. Odont, Department of Pediatric Dentistry and Clinical Genetics, University of Copenhagen; T. Herlin, Professor, MD, DMSc, Department of Pediatrics, Aarhus University Hospital; T.K. Pedersen, Professor, DDS, PhD, Section of Orthodontics, Aarhus University, and Department of Oral and Maxillofacial Surgery, Aarhus University Hospital. Address correspondence to Dr. M. Glerup, Department of Pediatrics, Aarhus University Hospital, Skejby, Palle Juul-Jensens Blvd. 99, 8200 Aarhus N, Denmark. E-mail: miagleru@rm.dk. Accepted for publication September 3, 2019.

From the Department of Pediatrics, Aarhus University Hospital; Section of Orthodontics, Aarhus University; Section of Oral Radiology, Department of Dentistry and Oral Health, Aarhus University, Aarhus, Denmark; Department of Pediatrics, University Hospital of North Norway, Tromsø; Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø; Department of Otorhinolaryngology and Department and Division of Oral and Maxillofacial Surgery, University Hospital North Norway and Public Dental Service Competence Center of North Norway, Tromsø; Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology (NTNU), Trondheim; Department of Pediatrics, Levanger Hospital, Nord-Trøndelag Hospital Trust, Levanger; Department of Pediatrics, St. Olavs Hospital, Trondheim; Department of Oral and Craniomaxillofacial Surgery, St. Olavs Hospital, Trondheim, Norway; Department of Pediatrics, Ryhov County Hospital, Jönköping; Department of Women’s and Children’s Health, Uppsala University, Uppsala; Department of Pediatrics, Sahlgrenska Academy, University of Gothenburg, Gothenburg; Department of Oral and Maxillofacial Surgery/Stomatognathic Physiology, The Institute for Postgraduate Dental Education, Jönköping, Sweden; Hospital for Children and Adolescents, University of Helsinki, Helsinki; Orthodontics, Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital, Helsinki, Finland; Department of Pediatrics, Copenhagen University Hospital, Copenhagen; Department of Pediatric Dentistry and Clinical Genetics, University of Copenhagen, Copenhagen; Department of Oral and Maxillofacial Surgery, Aarhus University Hospital, Aarhus, Denmark. M. Glerup, MD, Department of Pediatrics, Aarhus University Hospital; P. Stoustrup, Associate Professor, DDS, PhD, Section of Orthodontics, Aarhus University; L.H. Matzen, DDS, PhD, Associate Professor, Section of Oral Radiology, Department of Dentistry and Oral Health, Aarhus University; V. Rypdal, MD, Department of Pediatrics, University Hospital of North Norway, and Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway; E. Nordal, MD, PhD, Department of Pediatrics, University Hospital of North Norway, and Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway; P. Frid, DDS, Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, and Department of Otorhinolaryngology and Department and Division of Oral and Maxillofacial Surgery, University Hospital North Norway and Public Dental Service Competence Center of North Norway; E.D. Arnstad, MD, Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, NTNU, and Department of Pediatrics, Levanger Hospital, Nord-Trøndelag Hospital Trust; M. Rygg, MD, Professor, PhD, Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, NTNU, and Department of Pediatrics, St. Olavs Hospital; O. Thorarensen, DDS, Department of Oral and Craniomaxillofacial Surgery, St. Olavs Hospital; M. Ekelund, MD, Department of Pediatrics, Ryhov County Hospital, and Department of Women’s and Children’s Health, Uppsala University; L. Berntson, MD, PhD, Department of Women’s and Children’s Health, Uppsala University; A. Fasth, MD, PhD, Professor, Department of Pediatrics, Sahlgrenska Academy, University of Gothenburg; H. Nilsson, DDS, PhD, Dr. Odont, Department of Oral and Maxillofacial Surgery/Stomatognathic Physiology, The Institute for Postgraduate Dental Education; S. Peltoniemi, MD, Hospital for Children and Adolescents, University of Helsinki; K. Aalto, MD, PhD, Hospital for Children and Adolescents, University of Helsinki; S. Arte, DDS, PhD, Orthodontics, Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital; P. Toftedal, MD, PhD, Department of Pediatrics, Copenhagen University Hospital; S. Nielsen, MD, Department of Pediatrics, Copenhagen University Hospital; S. Kreiborg, Professor, DDS, PhD, Dr. Odont, Department of Pediatric Dentistry and Clinical Genetics, University of Copenhagen; T. Herlin, Professor, MD, DMSc, Department of Pediatrics, Aarhus University Hospital; T.K. Pedersen, Professor, DDS, PhD, Section of Orthodontics, Aarhus University, and Department of Oral and Maxillofacial Surgery, Aarhus University Hospital. Address correspondence to Dr. M. Glerup, Department of Pediatrics, Aarhus University Hospital, Skejby, Palle Juul-Jensens Blvd. 99, 8200 Aarhus N, Denmark. E-mail: miagleru@rm.dk. Accepted for publication September 3, 2019.

From the Department of Pediatrics, Aarhus University Hospital; Section of Orthodontics, Aarhus University; Section of Oral Radiology, Department of Dentistry and Oral Health, Aarhus University, Aarhus, Denmark; Department of Pediatrics, University Hospital of North Norway, Tromsø; Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø; Department of Otorhinolaryngology and Department and Division of Oral and Maxillofacial Surgery, University Hospital North Norway and Public Dental Service Competence Center of North Norway, Tromsø; Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology (NTNU), Trondheim; Department of Pediatrics, Levanger Hospital, Nord-Trøndelag Hospital Trust, Levanger; Department of Pediatrics, St. Olavs Hospital, Trondheim; Department of Oral and Craniomaxillofacial Surgery, St. Olavs Hospital, Trondheim, Norway; Department of Pediatrics, Ryhov County Hospital, Jönköping; Department of Women’s and Children’s Health, Uppsala University, Uppsala; Department of Pediatrics, Sahlgrenska Academy, University of Gothenburg, Gothenburg; Department of Oral and Maxillofacial Surgery/Stomatognathic Physiology, The Institute for Postgraduate Dental Education, Jönköping, Sweden; Hospital for Children and Adolescents, University of Helsinki, Helsinki; Orthodontics, Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital, Helsinki, Finland; Department of Pediatrics, Copenhagen University Hospital, Copenhagen; Department of Pediatric Dentistry and Clinical Genetics, University of Copenhagen, Copenhagen; Department of Oral and Maxillofacial Surgery, Aarhus University Hospital, Aarhus, Denmark. M. Glerup, MD, Department of Pediatrics, Aarhus University Hospital; P. Stoustrup, Associate Professor, DDS, PhD, Section of Orthodontics, Aarhus University; L.H. Matzen, DDS, PhD, Associate Professor, Section of Oral Radiology, Department of Dentistry and Oral Health, Aarhus University; V. Rypdal, MD, Department of Pediatrics, University Hospital of North Norway, and Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway; E. Nordal, MD, PhD, Department of Pediatrics, University Hospital of North Norway, and Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway; P. Frid, DDS, Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, and Department of Otorhinolaryngology and Department and Division of Oral and Maxillofacial Surgery, University Hospital North Norway and Public Dental Service Competence Center of North Norway; E.D. Arnstad, MD, Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, NTNU, and Department of Pediatrics, Levanger Hospital, Nord-Trøndelag Hospital Trust; M. Rygg, MD, Professor, PhD, Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, NTNU, and Department of Pediatrics, St. Olavs Hospital; O. Thorarensen, DDS, Department of Oral and Craniomaxillofacial Surgery, St. Olavs Hospital; M. Ekelund, MD, Department of Pediatrics, Ryhov County Hospital, and Department of Women’s and Children’s Health, Uppsala University; L. Berntson, MD, PhD, Department of Women’s and Children’s Health, Uppsala University; A. Fasth, MD, PhD, Professor, Department of Pediatrics, Sahlgrenska Academy, University of Gothenburg; H. Nilsson, DDS, PhD, Dr. Odont, Department of Oral and Maxillofacial Surgery/Stomatognathic Physiology, The Institute for Postgraduate Dental Education; S. Peltoniemi, MD, Hospital for Children and Adolescents, University of Helsinki; K. Aalto, MD, PhD, Hospital for Children and Adolescents, University of Helsinki; S. Arte, DDS, PhD, Orthodontics, Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital; P. Toftedal, MD, PhD, Department of Pediatrics, Copenhagen University Hospital; S. Nielsen, MD, Department of Pediatrics, Copenhagen University Hospital; S. Kreiborg, Professor, DDS, PhD, Dr. Odont, Department of Pediatric Dentistry and Clinical Genetics, University of Copenhagen; T. Herlin, Professor, MD, DMSc, Department of Pediatrics, Aarhus University Hospital; T.K. Pedersen, Professor, DDS, PhD, Section of Orthodontics, Aarhus University, and Department of Oral and Maxillofacial Surgery, Aarhus University Hospital. Address correspondence to Dr. M. Glerup, Department of Pediatrics, Aarhus University Hospital, Skejby, Palle Juul-Jensens Blvd. 99, 8200 Aarhus N, Denmark. E-mail: miagleru@rm.dk. Accepted for publication September 3, 2019.

From the Department of Pediatrics, Aarhus University Hospital; Section of Orthodontics, Aarhus University; Section of Oral Radiology, Department of Dentistry and Oral Health, Aarhus University, Aarhus, Denmark; Department of Pediatrics, University Hospital of North Norway, Tromsø; Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø; Department of Otorhinolaryngology and Department and Division of Oral and Maxillofacial Surgery, University Hospital North Norway and Public Dental Service Competence Center of North Norway, Tromsø; Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology (NTNU), Trondheim; Department of Pediatrics, Levanger Hospital, Nord-Trøndelag Hospital Trust, Levanger; Department of Pediatrics, St. Olavs Hospital, Trondheim; Department of Oral and Craniomaxillofacial Surgery, St. Olavs Hospital, Trondheim, Norway; Department of Pediatrics, Ryhov County Hospital, Jönköping; Department of Women’s and Children’s Health, Uppsala University, Uppsala; Department of Pediatrics, Sahlgrenska Academy, University of Gothenburg, Gothenburg; Department of Oral and Maxillofacial Surgery/Stomatognathic Physiology, The Institute for Postgraduate Dental Education, Jönköping, Sweden; Hospital for Children and Adolescents, University of Helsinki, Helsinki; Orthodontics, Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital, Helsinki, Finland; Department of Pediatrics, Copenhagen University Hospital, Copenhagen; Department of Pediatric Dentistry and Clinical Genetics, University of Copenhagen, Copenhagen; Department of Oral and Maxillofacial Surgery, Aarhus University Hospital, Aarhus, Denmark. M. Glerup, MD, Department of Pediatrics, Aarhus University Hospital; P. Stoustrup, Associate Professor, DDS, PhD, Section of Orthodontics, Aarhus University; L.H. Matzen, DDS, PhD, Associate Professor, Section of Oral Radiology, Department of Dentistry and Oral Health, Aarhus University; V. Rypdal, MD, Department of Pediatrics, University Hospital of North Norway, and Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway; E. Nordal, MD, PhD, Department of Pediatrics, University Hospital of North Norway, and Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway; P. Frid, DDS, Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, and Department of Otorhinolaryngology and Department and Division of Oral and Maxillofacial Surgery, University Hospital North Norway and Public Dental Service Competence Center of North Norway; E.D. Arnstad, MD, Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, NTNU, and Department of Pediatrics, Levanger Hospital, Nord-Trøndelag Hospital Trust; M. Rygg, MD, Professor, PhD, Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, NTNU, and Department of Pediatrics, St. Olavs Hospital; O. Thorarensen, DDS, Department of Oral and Craniomaxillofacial Surgery, St. Olavs Hospital; M. Ekelund, MD, Department of Pediatrics, Ryhov County Hospital, and Department of Women’s and Children’s Health, Uppsala University; L. Berntson, MD, PhD, Department of Women’s and Children’s Health, Uppsala University; A. Fasth, MD, PhD, Professor, Department of Pediatrics, Sahlgrenska Academy, University of Gothenburg; H. Nilsson, DDS, PhD, Dr. Odont, Department of Oral and Maxillofacial Surgery/Stomatognathic Physiology, The Institute for Postgraduate Dental Education; S. Peltoniemi, MD, Hospital for Children and Adolescents, University of Helsinki; K. Aalto, MD, PhD, Hospital for Children and Adolescents, University of Helsinki; S. Arte, DDS, PhD, Orthodontics, Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital; P. Toftedal, MD, PhD, Department of Pediatrics, Copenhagen University Hospital; S. Nielsen, MD, Department of Pediatrics, Copenhagen University Hospital; S. Kreiborg, Professor, DDS, PhD, Dr. Odont, Department of Pediatric Dentistry and Clinical Genetics, University of Copenhagen; T. Herlin, Professor, MD, DMSc, Department of Pediatrics, Aarhus University Hospital; T.K. Pedersen, Professor, DDS, PhD, Section of Orthodontics, Aarhus University, and Department of Oral and Maxillofacial Surgery, Aarhus University Hospital. Address correspondence to Dr. M. Glerup, Department of Pediatrics, Aarhus University Hospital, Skejby, Palle Juul-Jensens Blvd. 99, 8200 Aarhus N, Denmark. E-mail: miagleru@rm.dk. Accepted for publication September 3, 2019.

From the Department of Pediatrics, Aarhus University Hospital; Section of Orthodontics, Aarhus University; Section of Oral Radiology, Department of Dentistry and Oral Health, Aarhus University, Aarhus, Denmark; Department of Pediatrics, University Hospital of North Norway, Tromsø; Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø; Department of Otorhinolaryngology and Department and Division of Oral and Maxillofacial Surgery, University Hospital North Norway and Public Dental Service Competence Center of North Norway, Tromsø; Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology (NTNU), Trondheim; Department of Pediatrics, Levanger Hospital, Nord-Trøndelag Hospital Trust, Levanger; Department of Pediatrics, St. Olavs Hospital, Trondheim; Department of Oral and Craniomaxillofacial Surgery, St. Olavs Hospital, Trondheim, Norway; Department of Pediatrics, Ryhov County Hospital, Jönköping; Department of Women’s and Children’s Health, Uppsala University, Uppsala; Department of Pediatrics, Sahlgrenska Academy, University of Gothenburg, Gothenburg; Department of Oral and Maxillofacial Surgery/Stomatognathic Physiology, The Institute for Postgraduate Dental Education, Jönköping, Sweden; Hospital for Children and Adolescents, University of Helsinki, Helsinki; Orthodontics, Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital, Helsinki, Finland; Department of Pediatrics, Copenhagen University Hospital, Copenhagen; Department of Pediatric Dentistry and Clinical Genetics, University of Copenhagen, Copenhagen; Department of Oral and Maxillofacial Surgery, Aarhus University Hospital, Aarhus, Denmark. M. Glerup, MD, Department of Pediatrics, Aarhus University Hospital; P. Stoustrup, Associate Professor, DDS, PhD, Section of Orthodontics, Aarhus University; L.H. Matzen, DDS, PhD, Associate Professor, Section of Oral Radiology, Department of Dentistry and Oral Health, Aarhus University; V. Rypdal, MD, Department of Pediatrics, University Hospital of North Norway, and Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway; E. Nordal, MD, PhD, Department of Pediatrics, University Hospital of North Norway, and Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway; P. Frid, DDS, Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, and Department of Otorhinolaryngology and Department and Division of Oral and Maxillofacial Surgery, University Hospital North Norway and Public Dental Service Competence Center of North Norway; E.D. Arnstad, MD, Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, NTNU, and Department of Pediatrics, Levanger Hospital, Nord-Trøndelag Hospital Trust; M. Rygg, MD, Professor, PhD, Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, NTNU, and Department of Pediatrics, St. Olavs Hospital; O. Thorarensen, DDS, Department of Oral and Craniomaxillofacial Surgery, St. Olavs Hospital; M. Ekelund, MD, Department of Pediatrics, Ryhov County Hospital, and Department of Women’s and Children’s Health, Uppsala University; L. Berntson, MD, PhD, Department of Women’s and Children’s Health, Uppsala University; A. Fasth, MD, PhD, Professor, Department of Pediatrics, Sahlgrenska Academy, University of Gothenburg; H. Nilsson, DDS, PhD, Dr. Odont, Department of Oral and Maxillofacial Surgery/Stomatognathic Physiology, The Institute for Postgraduate Dental Education; S. Peltoniemi, MD, Hospital for Children and Adolescents, University of Helsinki; K. Aalto, MD, PhD, Hospital for Children and Adolescents, University of Helsinki; S. Arte, DDS, PhD, Orthodontics, Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital; P. Toftedal, MD, PhD, Department of Pediatrics, Copenhagen University Hospital; S. Nielsen, MD, Department of Pediatrics, Copenhagen University Hospital; S. Kreiborg, Professor, DDS, PhD, Dr. Odont, Department of Pediatric Dentistry and Clinical Genetics, University of Copenhagen; T. Herlin, Professor, MD, DMSc, Department of Pediatrics, Aarhus University Hospital; T.K. Pedersen, Professor, DDS, PhD, Section of Orthodontics, Aarhus University, and Department of Oral and Maxillofacial Surgery, Aarhus University Hospital. Address correspondence to Dr. M. Glerup, Department of Pediatrics, Aarhus University Hospital, Skejby, Palle Juul-Jensens Blvd. 99, 8200 Aarhus N, Denmark. E-mail: miagleru@rm.dk. Accepted for publication September 3, 2019.

From the Department of Pediatrics, Aarhus University Hospital; Section of Orthodontics, Aarhus University; Section of Oral Radiology, Department of Dentistry and Oral Health, Aarhus University, Aarhus, Denmark; Department of Pediatrics, University Hospital of North Norway, Tromsø; Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø; Department of Otorhinolaryngology and Department and Division of Oral and Maxillofacial Surgery, University Hospital North Norway and Public Dental Service Competence Center of North Norway, Tromsø; Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology (NTNU), Trondheim; Department of Pediatrics, Levanger Hospital, Nord-Trøndelag Hospital Trust, Levanger; Department of Pediatrics, St. Olavs Hospital, Trondheim; Department of Oral and Craniomaxillofacial Surgery, St. Olavs Hospital, Trondheim, Norway; Department of Pediatrics, Ryhov County Hospital, Jönköping; Department of Women’s and Children’s Health, Uppsala University, Uppsala; Department of Pediatrics, Sahlgrenska Academy, University of Gothenburg, Gothenburg; Department of Oral and Maxillofacial Surgery/Stomatognathic Physiology, The Institute for Postgraduate Dental Education, Jönköping, Sweden; Hospital for Children and Adolescents, University of Helsinki, Helsinki; Orthodontics, Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital, Helsinki, Finland; Department of Pediatrics, Copenhagen University Hospital, Copenhagen; Department of Pediatric Dentistry and Clinical Genetics, University of Copenhagen, Copenhagen; Department of Oral and Maxillofacial Surgery, Aarhus University Hospital, Aarhus, Denmark. M. Glerup, MD, Department of Pediatrics, Aarhus University Hospital; P. Stoustrup, Associate Professor, DDS, PhD, Section of Orthodontics, Aarhus University; L.H. Matzen, DDS, PhD, Associate Professor, Section of Oral Radiology, Department of Dentistry and Oral Health, Aarhus University; V. Rypdal, MD, Department of Pediatrics, University Hospital of North Norway, and Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway; E. Nordal, MD, PhD, Department of Pediatrics, University Hospital of North Norway, and Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway; P. Frid, DDS, Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, and Department of Otorhinolaryngology and Department and Division of Oral and Maxillofacial Surgery, University Hospital North Norway and Public Dental Service Competence Center of North Norway; E.D. Arnstad, MD, Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, NTNU, and Department of Pediatrics, Levanger Hospital, Nord-Trøndelag Hospital Trust; M. Rygg, MD, Professor, PhD, Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, NTNU, and Department of Pediatrics, St. Olavs Hospital; O. Thorarensen, DDS, Department of Oral and Craniomaxillofacial Surgery, St. Olavs Hospital; M. Ekelund, MD, Department of Pediatrics, Ryhov County Hospital, and Department of Women’s and Children’s Health, Uppsala University; L. Berntson, MD, PhD, Department of Women’s and Children’s Health, Uppsala University; A. Fasth, MD, PhD, Professor, Department of Pediatrics, Sahlgrenska Academy, University of Gothenburg; H. Nilsson, DDS, PhD, Dr. Odont, Department of Oral and Maxillofacial Surgery/Stomatognathic Physiology, The Institute for Postgraduate Dental Education; S. Peltoniemi, MD, Hospital for Children and Adolescents, University of Helsinki; K. Aalto, MD, PhD, Hospital for Children and Adolescents, University of Helsinki; S. Arte, DDS, PhD, Orthodontics, Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital; P. Toftedal, MD, PhD, Department of Pediatrics, Copenhagen University Hospital; S. Nielsen, MD, Department of Pediatrics, Copenhagen University Hospital; S. Kreiborg, Professor, DDS, PhD, Dr. Odont, Department of Pediatric Dentistry and Clinical Genetics, University of Copenhagen; T. Herlin, Professor, MD, DMSc, Department of Pediatrics, Aarhus University Hospital; T.K. Pedersen, Professor, DDS, PhD, Section of Orthodontics, Aarhus University, and Department of Oral and Maxillofacial Surgery, Aarhus University Hospital. Address correspondence to Dr. M. Glerup, Department of Pediatrics, Aarhus University Hospital, Skejby, Palle Juul-Jensens Blvd. 99, 8200 Aarhus N, Denmark. E-mail: miagleru@rm.dk. Accepted for publication September 3, 2019.

From the Department of Pediatrics, Aarhus University Hospital; Section of Orthodontics, Aarhus University; Section of Oral Radiology, Department of Dentistry and Oral Health, Aarhus University, Aarhus, Denmark; Department of Pediatrics, University Hospital of North Norway, Tromsø; Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø; Department of Otorhinolaryngology and Department and Division of Oral and Maxillofacial Surgery, University Hospital North Norway and Public Dental Service Competence Center of North Norway, Tromsø; Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology (NTNU), Trondheim; Department of Pediatrics, Levanger Hospital, Nord-Trøndelag Hospital Trust, Levanger; Department of Pediatrics, St. Olavs Hospital, Trondheim; Department of Oral and Craniomaxillofacial Surgery, St. Olavs Hospital, Trondheim, Norway; Department of Pediatrics, Ryhov County Hospital, Jönköping; Department of Women’s and Children’s Health, Uppsala University, Uppsala; Department of Pediatrics, Sahlgrenska Academy, University of Gothenburg, Gothenburg; Department of Oral and Maxillofacial Surgery/Stomatognathic Physiology, The Institute for Postgraduate Dental Education, Jönköping, Sweden; Hospital for Children and Adolescents, University of Helsinki, Helsinki; Orthodontics, Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital, Helsinki, Finland; Department of Pediatrics, Copenhagen University Hospital, Copenhagen; Department of Pediatric Dentistry and Clinical Genetics, University of Copenhagen, Copenhagen; Department of Oral and Maxillofacial Surgery, Aarhus University Hospital, Aarhus, Denmark. M. Glerup, MD, Department of Pediatrics, Aarhus University Hospital; P. Stoustrup, Associate Professor, DDS, PhD, Section of Orthodontics, Aarhus University; L.H. Matzen, DDS, PhD, Associate Professor, Section of Oral Radiology, Department of Dentistry and Oral Health, Aarhus University; V. Rypdal, MD, Department of Pediatrics, University Hospital of North Norway, and Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway; E. Nordal, MD, PhD, Department of Pediatrics, University Hospital of North Norway, and Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway; P. Frid, DDS, Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, and Department of Otorhinolaryngology and Department and Division of Oral and Maxillofacial Surgery, University Hospital North Norway and Public Dental Service Competence Center of North Norway; E.D. Arnstad, MD, Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, NTNU, and Department of Pediatrics, Levanger Hospital, Nord-Trøndelag Hospital Trust; M. Rygg, MD, Professor, PhD, Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, NTNU, and Department of Pediatrics, St. Olavs Hospital; O. Thorarensen, DDS, Department of Oral and Craniomaxillofacial Surgery, St. Olavs Hospital; M. Ekelund, MD, Department of Pediatrics, Ryhov County Hospital, and Department of Women’s and Children’s Health, Uppsala University; L. Berntson, MD, PhD, Department of Women’s and Children’s Health, Uppsala University; A. Fasth, MD, PhD, Professor, Department of Pediatrics, Sahlgrenska Academy, University of Gothenburg; H. Nilsson, DDS, PhD, Dr. Odont, Department of Oral and Maxillofacial Surgery/Stomatognathic Physiology, The Institute for Postgraduate Dental Education; S. Peltoniemi, MD, Hospital for Children and Adolescents, University of Helsinki; K. Aalto, MD, PhD, Hospital for Children and Adolescents, University of Helsinki; S. Arte, DDS, PhD, Orthodontics, Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital; P. Toftedal, MD, PhD, Department of Pediatrics, Copenhagen University Hospital; S. Nielsen, MD, Department of Pediatrics, Copenhagen University Hospital; S. Kreiborg, Professor, DDS, PhD, Dr. Odont, Department of Pediatric Dentistry and Clinical Genetics, University of Copenhagen; T. Herlin, Professor, MD, DMSc, Department of Pediatrics, Aarhus University Hospital; T.K. Pedersen, Professor, DDS, PhD, Section of Orthodontics, Aarhus University, and Department of Oral and Maxillofacial Surgery, Aarhus University Hospital. Address correspondence to Dr. M. Glerup, Department of Pediatrics, Aarhus University Hospital, Skejby, Palle Juul-Jensens Blvd. 99, 8200 Aarhus N, Denmark. E-mail: miagleru@rm.dk. Accepted for publication September 3, 2019.

From the Department of Pediatrics, Aarhus University Hospital; Section of Orthodontics, Aarhus University; Section of Oral Radiology, Department of Dentistry and Oral Health, Aarhus University, Aarhus, Denmark; Department of Pediatrics, University Hospital of North Norway, Tromsø; Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø; Department of Otorhinolaryngology and Department and Division of Oral and Maxillofacial Surgery, University Hospital North Norway and Public Dental Service Competence Center of North Norway, Tromsø; Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology (NTNU), Trondheim; Department of Pediatrics, Levanger Hospital, Nord-Trøndelag Hospital Trust, Levanger; Department of Pediatrics, St. Olavs Hospital, Trondheim; Department of Oral and Craniomaxillofacial Surgery, St. Olavs Hospital, Trondheim, Norway; Department of Pediatrics, Ryhov County Hospital, Jönköping; Department of Women’s and Children’s Health, Uppsala University, Uppsala; Department of Pediatrics, Sahlgrenska Academy, University of Gothenburg, Gothenburg; Department of Oral and Maxillofacial Surgery/Stomatognathic Physiology, The Institute for Postgraduate Dental Education, Jönköping, Sweden; Hospital for Children and Adolescents, University of Helsinki, Helsinki; Orthodontics, Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital, Helsinki, Finland; Department of Pediatrics, Copenhagen University Hospital, Copenhagen; Department of Pediatric Dentistry and Clinical Genetics, University of Copenhagen, Copenhagen; Department of Oral and Maxillofacial Surgery, Aarhus University Hospital, Aarhus, Denmark. M. Glerup, MD, Department of Pediatrics, Aarhus University Hospital; P. Stoustrup, Associate Professor, DDS, PhD, Section of Orthodontics, Aarhus University; L.H. Matzen, DDS, PhD, Associate Professor, Section of Oral Radiology, Department of Dentistry and Oral Health, Aarhus University; V. Rypdal, MD, Department of Pediatrics, University Hospital of North Norway, and Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway; E. Nordal, MD, PhD, Department of Pediatrics, University Hospital of North Norway, and Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway; P. Frid, DDS, Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, and Department of Otorhinolaryngology and Department and Division of Oral and Maxillofacial Surgery, University Hospital North Norway and Public Dental Service Competence Center of North Norway; E.D. Arnstad, MD, Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, NTNU, and Department of Pediatrics, Levanger Hospital, Nord-Trøndelag Hospital Trust; M. Rygg, MD, Professor, PhD, Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, NTNU, and Department of Pediatrics, St. Olavs Hospital; O. Thorarensen, DDS, Department of Oral and Craniomaxillofacial Surgery, St. Olavs Hospital; M. Ekelund, MD, Department of Pediatrics, Ryhov County Hospital, and Department of Women’s and Children’s Health, Uppsala University; L. Berntson, MD, PhD, Department of Women’s and Children’s Health, Uppsala University; A. Fasth, MD, PhD, Professor, Department of Pediatrics, Sahlgrenska Academy, University of Gothenburg; H. Nilsson, DDS, PhD, Dr. Odont, Department of Oral and Maxillofacial Surgery/Stomatognathic Physiology, The Institute for Postgraduate Dental Education; S. Peltoniemi, MD, Hospital for Children and Adolescents, University of Helsinki; K. Aalto, MD, PhD, Hospital for Children and Adolescents, University of Helsinki; S. Arte, DDS, PhD, Orthodontics, Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital; P. Toftedal, MD, PhD, Department of Pediatrics, Copenhagen University Hospital; S. Nielsen, MD, Department of Pediatrics, Copenhagen University Hospital; S. Kreiborg, Professor, DDS, PhD, Dr. Odont, Department of Pediatric Dentistry and Clinical Genetics, University of Copenhagen; T. Herlin, Professor, MD, DMSc, Department of Pediatrics, Aarhus University Hospital; T.K. Pedersen, Professor, DDS, PhD, Section of Orthodontics, Aarhus University, and Department of Oral and Maxillofacial Surgery, Aarhus University Hospital. Address correspondence to Dr. M. Glerup, Department of Pediatrics, Aarhus University Hospital, Skejby, Palle Juul-Jensens Blvd. 99, 8200 Aarhus N, Denmark. E-mail: miagleru@rm.dk. Accepted for publication September 3, 2019.

From the Department of Pediatrics, Aarhus University Hospital; Section of Orthodontics, Aarhus University; Section of Oral Radiology, Department of Dentistry and Oral Health, Aarhus University, Aarhus, Denmark; Department of Pediatrics, University Hospital of North Norway, Tromsø; Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø; Department of Otorhinolaryngology and Department and Division of Oral and Maxillofacial Surgery, University Hospital North Norway and Public Dental Service Competence Center of North Norway, Tromsø; Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology (NTNU), Trondheim; Department of Pediatrics, Levanger Hospital, Nord-Trøndelag Hospital Trust, Levanger; Department of Pediatrics, St. Olavs Hospital, Trondheim; Department of Oral and Craniomaxillofacial Surgery, St. Olavs Hospital, Trondheim, Norway; Department of Pediatrics, Ryhov County Hospital, Jönköping; Department of Women’s and Children’s Health, Uppsala University, Uppsala; Department of Pediatrics, Sahlgrenska Academy, University of Gothenburg, Gothenburg; Department of Oral and Maxillofacial Surgery/Stomatognathic Physiology, The Institute for Postgraduate Dental Education, Jönköping, Sweden; Hospital for Children and Adolescents, University of Helsinki, Helsinki; Orthodontics, Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital, Helsinki, Finland; Department of Pediatrics, Copenhagen University Hospital, Copenhagen; Department of Pediatric Dentistry and Clinical Genetics, University of Copenhagen, Copenhagen; Department of Oral and Maxillofacial Surgery, Aarhus University Hospital, Aarhus, Denmark. M. Glerup, MD, Department of Pediatrics, Aarhus University Hospital; P. Stoustrup, Associate Professor, DDS, PhD, Section of Orthodontics, Aarhus University; L.H. Matzen, DDS, PhD, Associate Professor, Section of Oral Radiology, Department of Dentistry and Oral Health, Aarhus University; V. Rypdal, MD, Department of Pediatrics, University Hospital of North Norway, and Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway; E. Nordal, MD, PhD, Department of Pediatrics, University Hospital of North Norway, and Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway; P. Frid, DDS, Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, and Department of Otorhinolaryngology and Department and Division of Oral and Maxillofacial Surgery, University Hospital North Norway and Public Dental Service Competence Center of North Norway; E.D. Arnstad, MD, Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, NTNU, and Department of Pediatrics, Levanger Hospital, Nord-Trøndelag Hospital Trust; M. Rygg, MD, Professor, PhD, Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, NTNU, and Department of Pediatrics, St. Olavs Hospital; O. Thorarensen, DDS, Department of Oral and Craniomaxillofacial Surgery, St. Olavs Hospital; M. Ekelund, MD, Department of Pediatrics, Ryhov County Hospital, and Department of Women’s and Children’s Health, Uppsala University; L. Berntson, MD, PhD, Department of Women’s and Children’s Health, Uppsala University; A. Fasth, MD, PhD, Professor, Department of Pediatrics, Sahlgrenska Academy, University of Gothenburg; H. Nilsson, DDS, PhD, Dr. Odont, Department of Oral and Maxillofacial Surgery/Stomatognathic Physiology, The Institute for Postgraduate Dental Education; S. Peltoniemi, MD, Hospital for Children and Adolescents, University of Helsinki; K. Aalto, MD, PhD, Hospital for Children and Adolescents, University of Helsinki; S. Arte, DDS, PhD, Orthodontics, Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital; P. Toftedal, MD, PhD, Department of Pediatrics, Copenhagen University Hospital; S. Nielsen, MD, Department of Pediatrics, Copenhagen University Hospital; S. Kreiborg, Professor, DDS, PhD, Dr. Odont, Department of Pediatric Dentistry and Clinical Genetics, University of Copenhagen; T. Herlin, Professor, MD, DMSc, Department of Pediatrics, Aarhus University Hospital; T.K. Pedersen, Professor, DDS, PhD, Section of Orthodontics, Aarhus University, and Department of Oral and Maxillofacial Surgery, Aarhus University Hospital. Address correspondence to Dr. M. Glerup, Department of Pediatrics, Aarhus University Hospital, Skejby, Palle Juul-Jensens Blvd. 99, 8200 Aarhus N, Denmark. E-mail: miagleru@rm.dk. Accepted for publication September 3, 2019.

From the Department of Pediatrics, Aarhus University Hospital; Section of Orthodontics, Aarhus University; Section of Oral Radiology, Department of Dentistry and Oral Health, Aarhus University, Aarhus, Denmark; Department of Pediatrics, University Hospital of North Norway, Tromsø; Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø; Department of Otorhinolaryngology and Department and Division of Oral and Maxillofacial Surgery, University Hospital North Norway and Public Dental Service Competence Center of North Norway, Tromsø; Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology (NTNU), Trondheim; Department of Pediatrics, Levanger Hospital, Nord-Trøndelag Hospital Trust, Levanger; Department of Pediatrics, St. Olavs Hospital, Trondheim; Department of Oral and Craniomaxillofacial Surgery, St. Olavs Hospital, Trondheim, Norway; Department of Pediatrics, Ryhov County Hospital, Jönköping; Department of Women’s and Children’s Health, Uppsala University, Uppsala; Department of Pediatrics, Sahlgrenska Academy, University of Gothenburg, Gothenburg; Department of Oral and Maxillofacial Surgery/Stomatognathic Physiology, The Institute for Postgraduate Dental Education, Jönköping, Sweden; Hospital for Children and Adolescents, University of Helsinki, Helsinki; Orthodontics, Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital, Helsinki, Finland; Department of Pediatrics, Copenhagen University Hospital, Copenhagen; Department of Pediatric Dentistry and Clinical Genetics, University of Copenhagen, Copenhagen; Department of Oral and Maxillofacial Surgery, Aarhus University Hospital, Aarhus, Denmark. M. Glerup, MD, Department of Pediatrics, Aarhus University Hospital; P. Stoustrup, Associate Professor, DDS, PhD, Section of Orthodontics, Aarhus University; L.H. Matzen, DDS, PhD, Associate Professor, Section of Oral Radiology, Department of Dentistry and Oral Health, Aarhus University; V. Rypdal, MD, Department of Pediatrics, University Hospital of North Norway, and Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway; E. Nordal, MD, PhD, Department of Pediatrics, University Hospital of North Norway, and Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway; P. Frid, DDS, Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, and Department of Otorhinolaryngology and Department and Division of Oral and Maxillofacial Surgery, University Hospital North Norway and Public Dental Service Competence Center of North Norway; E.D. Arnstad, MD, Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, NTNU, and Department of Pediatrics, Levanger Hospital, Nord-Trøndelag Hospital Trust; M. Rygg, MD, Professor, PhD, Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, NTNU, and Department of Pediatrics, St. Olavs Hospital; O. Thorarensen, DDS, Department of Oral and Craniomaxillofacial Surgery, St. Olavs Hospital; M. Ekelund, MD, Department of Pediatrics, Ryhov County Hospital, and Department of Women’s and Children’s Health, Uppsala University; L. Berntson, MD, PhD, Department of Women’s and Children’s Health, Uppsala University; A. Fasth, MD, PhD, Professor, Department of Pediatrics, Sahlgrenska Academy, University of Gothenburg; H. Nilsson, DDS, PhD, Dr. Odont, Department of Oral and Maxillofacial Surgery/Stomatognathic Physiology, The Institute for Postgraduate Dental Education; S. Peltoniemi, MD, Hospital for Children and Adolescents, University of Helsinki; K. Aalto, MD, PhD, Hospital for Children and Adolescents, University of Helsinki; S. Arte, DDS, PhD, Orthodontics, Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital; P. Toftedal, MD, PhD, Department of Pediatrics, Copenhagen University Hospital; S. Nielsen, MD, Department of Pediatrics, Copenhagen University Hospital; S. Kreiborg, Professor, DDS, PhD, Dr. Odont, Department of Pediatric Dentistry and Clinical Genetics, University of Copenhagen; T. Herlin, Professor, MD, DMSc, Department of Pediatrics, Aarhus University Hospital; T.K. Pedersen, Professor, DDS, PhD, Section of Orthodontics, Aarhus University, and Department of Oral and Maxillofacial Surgery, Aarhus University Hospital. Address correspondence to Dr. M. Glerup, Department of Pediatrics, Aarhus University Hospital, Skejby, Palle Juul-Jensens Blvd. 99, 8200 Aarhus N, Denmark. E-mail: miagleru@rm.dk. Accepted for publication September 3, 2019.

From the Department of Pediatrics, Aarhus University Hospital; Section of Orthodontics, Aarhus University; Section of Oral Radiology, Department of Dentistry and Oral Health, Aarhus University, Aarhus, Denmark; Department of Pediatrics, University Hospital of North Norway, Tromsø; Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø; Department of Otorhinolaryngology and Department and Division of Oral and Maxillofacial Surgery, University Hospital North Norway and Public Dental Service Competence Center of North Norway, Tromsø; Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology (NTNU), Trondheim; Department of Pediatrics, Levanger Hospital, Nord-Trøndelag Hospital Trust, Levanger; Department of Pediatrics, St. Olavs Hospital, Trondheim; Department of Oral and Craniomaxillofacial Surgery, St. Olavs Hospital, Trondheim, Norway; Department of Pediatrics, Ryhov County Hospital, Jönköping; Department of Women’s and Children’s Health, Uppsala University, Uppsala; Department of Pediatrics, Sahlgrenska Academy, University of Gothenburg, Gothenburg; Department of Oral and Maxillofacial Surgery/Stomatognathic Physiology, The Institute for Postgraduate Dental Education, Jönköping, Sweden; Hospital for Children and Adolescents, University of Helsinki, Helsinki; Orthodontics, Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital, Helsinki, Finland; Department of Pediatrics, Copenhagen University Hospital, Copenhagen; Department of Pediatric Dentistry and Clinical Genetics, University of Copenhagen, Copenhagen; Department of Oral and Maxillofacial Surgery, Aarhus University Hospital, Aarhus, Denmark. M. Glerup, MD, Department of Pediatrics, Aarhus University Hospital; P. Stoustrup, Associate Professor, DDS, PhD, Section of Orthodontics, Aarhus University; L.H. Matzen, DDS, PhD, Associate Professor, Section of Oral Radiology, Department of Dentistry and Oral Health, Aarhus University; V. Rypdal, MD, Department of Pediatrics, University Hospital of North Norway, and Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway; E. Nordal, MD, PhD, Department of Pediatrics, University Hospital of North Norway, and Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway; P. Frid, DDS, Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, and Department of Otorhinolaryngology and Department and Division of Oral and Maxillofacial Surgery, University Hospital North Norway and Public Dental Service Competence Center of North Norway; E.D. Arnstad, MD, Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, NTNU, and Department of Pediatrics, Levanger Hospital, Nord-Trøndelag Hospital Trust; M. Rygg, MD, Professor, PhD, Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, NTNU, and Department of Pediatrics, St. Olavs Hospital; O. Thorarensen, DDS, Department of Oral and Craniomaxillofacial Surgery, St. Olavs Hospital; M. Ekelund, MD, Department of Pediatrics, Ryhov County Hospital, and Department of Women’s and Children’s Health, Uppsala University; L. Berntson, MD, PhD, Department of Women’s and Children’s Health, Uppsala University; A. Fasth, MD, PhD, Professor, Department of Pediatrics, Sahlgrenska Academy, University of Gothenburg; H. Nilsson, DDS, PhD, Dr. Odont, Department of Oral and Maxillofacial Surgery/Stomatognathic Physiology, The Institute for Postgraduate Dental Education; S. Peltoniemi, MD, Hospital for Children and Adolescents, University of Helsinki; K. Aalto, MD, PhD, Hospital for Children and Adolescents, University of Helsinki; S. Arte, DDS, PhD, Orthodontics, Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital; P. Toftedal, MD, PhD, Department of Pediatrics, Copenhagen University Hospital; S. Nielsen, MD, Department of Pediatrics, Copenhagen University Hospital; S. Kreiborg, Professor, DDS, PhD, Dr. Odont, Department of Pediatric Dentistry and Clinical Genetics, University of Copenhagen; T. Herlin, Professor, MD, DMSc, Department of Pediatrics, Aarhus University Hospital; T.K. Pedersen, Professor, DDS, PhD, Section of Orthodontics, Aarhus University, and Department of Oral and Maxillofacial Surgery, Aarhus University Hospital. Address correspondence to Dr. M. Glerup, Department of Pediatrics, Aarhus University Hospital, Skejby, Palle Juul-Jensens Blvd. 99, 8200 Aarhus N, Denmark. E-mail: miagleru@rm.dk. Accepted for publication September 3, 2019.

From the Department of Pediatrics, Aarhus University Hospital; Section of Orthodontics, Aarhus University; Section of Oral Radiology, Department of Dentistry and Oral Health, Aarhus University, Aarhus, Denmark; Department of Pediatrics, University Hospital of North Norway, Tromsø; Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø; Department of Otorhinolaryngology and Department and Division of Oral and Maxillofacial Surgery, University Hospital North Norway and Public Dental Service Competence Center of North Norway, Tromsø; Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology (NTNU), Trondheim; Department of Pediatrics, Levanger Hospital, Nord-Trøndelag Hospital Trust, Levanger; Department of Pediatrics, St. Olavs Hospital, Trondheim; Department of Oral and Craniomaxillofacial Surgery, St. Olavs Hospital, Trondheim, Norway; Department of Pediatrics, Ryhov County Hospital, Jönköping; Department of Women’s and Children’s Health, Uppsala University, Uppsala; Department of Pediatrics, Sahlgrenska Academy, University of Gothenburg, Gothenburg; Department of Oral and Maxillofacial Surgery/Stomatognathic Physiology, The Institute for Postgraduate Dental Education, Jönköping, Sweden; Hospital for Children and Adolescents, University of Helsinki, Helsinki; Orthodontics, Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital, Helsinki, Finland; Department of Pediatrics, Copenhagen University Hospital, Copenhagen; Department of Pediatric Dentistry and Clinical Genetics, University of Copenhagen, Copenhagen; Department of Oral and Maxillofacial Surgery, Aarhus University Hospital, Aarhus, Denmark. M. Glerup, MD, Department of Pediatrics, Aarhus University Hospital; P. Stoustrup, Associate Professor, DDS, PhD, Section of Orthodontics, Aarhus University; L.H. Matzen, DDS, PhD, Associate Professor, Section of Oral Radiology, Department of Dentistry and Oral Health, Aarhus University; V. Rypdal, MD, Department of Pediatrics, University Hospital of North Norway, and Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway; E. Nordal, MD, PhD, Department of Pediatrics, University Hospital of North Norway, and Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway; P. Frid, DDS, Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, and Department of Otorhinolaryngology and Department and Division of Oral and Maxillofacial Surgery, University Hospital North Norway and Public Dental Service Competence Center of North Norway; E.D. Arnstad, MD, Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, NTNU, and Department of Pediatrics, Levanger Hospital, Nord-Trøndelag Hospital Trust; M. Rygg, MD, Professor, PhD, Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, NTNU, and Department of Pediatrics, St. Olavs Hospital; O. Thorarensen, DDS, Department of Oral and Craniomaxillofacial Surgery, St. Olavs Hospital; M. Ekelund, MD, Department of Pediatrics, Ryhov County Hospital, and Department of Women’s and Children’s Health, Uppsala University; L. Berntson, MD, PhD, Department of Women’s and Children’s Health, Uppsala University; A. Fasth, MD, PhD, Professor, Department of Pediatrics, Sahlgrenska Academy, University of Gothenburg; H. Nilsson, DDS, PhD, Dr. Odont, Department of Oral and Maxillofacial Surgery/Stomatognathic Physiology, The Institute for Postgraduate Dental Education; S. Peltoniemi, MD, Hospital for Children and Adolescents, University of Helsinki; K. Aalto, MD, PhD, Hospital for Children and Adolescents, University of Helsinki; S. Arte, DDS, PhD, Orthodontics, Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital; P. Toftedal, MD, PhD, Department of Pediatrics, Copenhagen University Hospital; S. Nielsen, MD, Department of Pediatrics, Copenhagen University Hospital; S. Kreiborg, Professor, DDS, PhD, Dr. Odont, Department of Pediatric Dentistry and Clinical Genetics, University of Copenhagen; T. Herlin, Professor, MD, DMSc, Department of Pediatrics, Aarhus University Hospital; T.K. Pedersen, Professor, DDS, PhD, Section of Orthodontics, Aarhus University, and Department of Oral and Maxillofacial Surgery, Aarhus University Hospital. Address correspondence to Dr. M. Glerup, Department of Pediatrics, Aarhus University Hospital, Skejby, Palle Juul-Jensens Blvd. 99, 8200 Aarhus N, Denmark. E-mail: miagleru@rm.dk. Accepted for publication September 3, 2019.

From the Department of Pediatrics, Aarhus University Hospital; Section of Orthodontics, Aarhus University; Section of Oral Radiology, Department of Dentistry and Oral Health, Aarhus University, Aarhus, Denmark; Department of Pediatrics, University Hospital of North Norway, Tromsø; Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø; Department of Otorhinolaryngology and Department and Division of Oral and Maxillofacial Surgery, University Hospital North Norway and Public Dental Service Competence Center of North Norway, Tromsø; Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology (NTNU), Trondheim; Department of Pediatrics, Levanger Hospital, Nord-Trøndelag Hospital Trust, Levanger; Department of Pediatrics, St. Olavs Hospital, Trondheim; Department of Oral and Craniomaxillofacial Surgery, St. Olavs Hospital, Trondheim, Norway; Department of Pediatrics, Ryhov County Hospital, Jönköping; Department of Women’s and Children’s Health, Uppsala University, Uppsala; Department of Pediatrics, Sahlgrenska Academy, University of Gothenburg, Gothenburg; Department of Oral and Maxillofacial Surgery/Stomatognathic Physiology, The Institute for Postgraduate Dental Education, Jönköping, Sweden; Hospital for Children and Adolescents, University of Helsinki, Helsinki; Orthodontics, Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital, Helsinki, Finland; Department of Pediatrics, Copenhagen University Hospital, Copenhagen; Department of Pediatric Dentistry and Clinical Genetics, University of Copenhagen, Copenhagen; Department of Oral and Maxillofacial Surgery, Aarhus University Hospital, Aarhus, Denmark. M. Glerup, MD, Department of Pediatrics, Aarhus University Hospital; P. Stoustrup, Associate Professor, DDS, PhD, Section of Orthodontics, Aarhus University; L.H. Matzen, DDS, PhD, Associate Professor, Section of Oral Radiology, Department of Dentistry and Oral Health, Aarhus University; V. Rypdal, MD, Department of Pediatrics, University Hospital of North Norway, and Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway; E. Nordal, MD, PhD, Department of Pediatrics, University Hospital of North Norway, and Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway; P. Frid, DDS, Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, and Department of Otorhinolaryngology and Department and Division of Oral and Maxillofacial Surgery, University Hospital North Norway and Public Dental Service Competence Center of North Norway; E.D. Arnstad, MD, Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, NTNU, and Department of Pediatrics, Levanger Hospital, Nord-Trøndelag Hospital Trust; M. Rygg, MD, Professor, PhD, Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, NTNU, and Department of Pediatrics, St. Olavs Hospital; O. Thorarensen, DDS, Department of Oral and Craniomaxillofacial Surgery, St. Olavs Hospital; M. Ekelund, MD, Department of Pediatrics, Ryhov County Hospital, and Department of Women’s and Children’s Health, Uppsala University; L. Berntson, MD, PhD, Department of Women’s and Children’s Health, Uppsala University; A. Fasth, MD, PhD, Professor, Department of Pediatrics, Sahlgrenska Academy, University of Gothenburg; H. Nilsson, DDS, PhD, Dr. Odont, Department of Oral and Maxillofacial Surgery/Stomatognathic Physiology, The Institute for Postgraduate Dental Education; S. Peltoniemi, MD, Hospital for Children and Adolescents, University of Helsinki; K. Aalto, MD, PhD, Hospital for Children and Adolescents, University of Helsinki; S. Arte, DDS, PhD, Orthodontics, Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital; P. Toftedal, MD, PhD, Department of Pediatrics, Copenhagen University Hospital; S. Nielsen, MD, Department of Pediatrics, Copenhagen University Hospital; S. Kreiborg, Professor, DDS, PhD, Dr. Odont, Department of Pediatric Dentistry and Clinical Genetics, University of Copenhagen; T. Herlin, Professor, MD, DMSc, Department of Pediatrics, Aarhus University Hospital; T.K. Pedersen, Professor, DDS, PhD, Section of Orthodontics, Aarhus University, and Department of Oral and Maxillofacial Surgery, Aarhus University Hospital. Address correspondence to Dr. M. Glerup, Department of Pediatrics, Aarhus University Hospital, Skejby, Palle Juul-Jensens Blvd. 99, 8200 Aarhus N, Denmark. E-mail: miagleru@rm.dk. Accepted for publication September 3, 2019.

From the Department of Pediatrics, Aarhus University Hospital; Section of Orthodontics, Aarhus University; Section of Oral Radiology, Department of Dentistry and Oral Health, Aarhus University, Aarhus, Denmark; Department of Pediatrics, University Hospital of North Norway, Tromsø; Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø; Department of Otorhinolaryngology and Department and Division of Oral and Maxillofacial Surgery, University Hospital North Norway and Public Dental Service Competence Center of North Norway, Tromsø; Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology (NTNU), Trondheim; Department of Pediatrics, Levanger Hospital, Nord-Trøndelag Hospital Trust, Levanger; Department of Pediatrics, St. Olavs Hospital, Trondheim; Department of Oral and Craniomaxillofacial Surgery, St. Olavs Hospital, Trondheim, Norway; Department of Pediatrics, Ryhov County Hospital, Jönköping; Department of Women’s and Children’s Health, Uppsala University, Uppsala; Department of Pediatrics, Sahlgrenska Academy, University of Gothenburg, Gothenburg; Department of Oral and Maxillofacial Surgery/Stomatognathic Physiology, The Institute for Postgraduate Dental Education, Jönköping, Sweden; Hospital for Children and Adolescents, University of Helsinki, Helsinki; Orthodontics, Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital, Helsinki, Finland; Department of Pediatrics, Copenhagen University Hospital, Copenhagen; Department of Pediatric Dentistry and Clinical Genetics, University of Copenhagen, Copenhagen; Department of Oral and Maxillofacial Surgery, Aarhus University Hospital, Aarhus, Denmark. M. Glerup, MD, Department of Pediatrics, Aarhus University Hospital; P. Stoustrup, Associate Professor, DDS, PhD, Section of Orthodontics, Aarhus University; L.H. Matzen, DDS, PhD, Associate Professor, Section of Oral Radiology, Department of Dentistry and Oral Health, Aarhus University; V. Rypdal, MD, Department of Pediatrics, University Hospital of North Norway, and Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway; E. Nordal, MD, PhD, Department of Pediatrics, University Hospital of North Norway, and Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway; P. Frid, DDS, Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, and Department of Otorhinolaryngology and Department and Division of Oral and Maxillofacial Surgery, University Hospital North Norway and Public Dental Service Competence Center of North Norway; E.D. Arnstad, MD, Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, NTNU, and Department of Pediatrics, Levanger Hospital, Nord-Trøndelag Hospital Trust; M. Rygg, MD, Professor, PhD, Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, NTNU, and Department of Pediatrics, St. Olavs Hospital; O. Thorarensen, DDS, Department of Oral and Craniomaxillofacial Surgery, St. Olavs Hospital; M. Ekelund, MD, Department of Pediatrics, Ryhov County Hospital, and Department of Women’s and Children’s Health, Uppsala University; L. Berntson, MD, PhD, Department of Women’s and Children’s Health, Uppsala University; A. Fasth, MD, PhD, Professor, Department of Pediatrics, Sahlgrenska Academy, University of Gothenburg; H. Nilsson, DDS, PhD, Dr. Odont, Department of Oral and Maxillofacial Surgery/Stomatognathic Physiology, The Institute for Postgraduate Dental Education; S. Peltoniemi, MD, Hospital for Children and Adolescents, University of Helsinki; K. Aalto, MD, PhD, Hospital for Children and Adolescents, University of Helsinki; S. Arte, DDS, PhD, Orthodontics, Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital; P. Toftedal, MD, PhD, Department of Pediatrics, Copenhagen University Hospital; S. Nielsen, MD, Department of Pediatrics, Copenhagen University Hospital; S. Kreiborg, Professor, DDS, PhD, Dr. Odont, Department of Pediatric Dentistry and Clinical Genetics, University of Copenhagen; T. Herlin, Professor, MD, DMSc, Department of Pediatrics, Aarhus University Hospital; T.K. Pedersen, Professor, DDS, PhD, Section of Orthodontics, Aarhus University, and Department of Oral and Maxillofacial Surgery, Aarhus University Hospital. Address correspondence to Dr. M. Glerup, Department of Pediatrics, Aarhus University Hospital, Skejby, Palle Juul-Jensens Blvd. 99, 8200 Aarhus N, Denmark. E-mail: miagleru@rm.dk. Accepted for publication September 3, 2019.

From the Department of Pediatrics, Aarhus University Hospital; Section of Orthodontics, Aarhus University; Section of Oral Radiology, Department of Dentistry and Oral Health, Aarhus University, Aarhus, Denmark; Department of Pediatrics, University Hospital of North Norway, Tromsø; Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø; Department of Otorhinolaryngology and Department and Division of Oral and Maxillofacial Surgery, University Hospital North Norway and Public Dental Service Competence Center of North Norway, Tromsø; Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology (NTNU), Trondheim; Department of Pediatrics, Levanger Hospital, Nord-Trøndelag Hospital Trust, Levanger; Department of Pediatrics, St. Olavs Hospital, Trondheim; Department of Oral and Craniomaxillofacial Surgery, St. Olavs Hospital, Trondheim, Norway; Department of Pediatrics, Ryhov County Hospital, Jönköping; Department of Women’s and Children’s Health, Uppsala University, Uppsala; Department of Pediatrics, Sahlgrenska Academy, University of Gothenburg, Gothenburg; Department of Oral and Maxillofacial Surgery/Stomatognathic Physiology, The Institute for Postgraduate Dental Education, Jönköping, Sweden; Hospital for Children and Adolescents, University of Helsinki, Helsinki; Orthodontics, Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital, Helsinki, Finland; Department of Pediatrics, Copenhagen University Hospital, Copenhagen; Department of Pediatric Dentistry and Clinical Genetics, University of Copenhagen, Copenhagen; Department of Oral and Maxillofacial Surgery, Aarhus University Hospital, Aarhus, Denmark. M. Glerup, MD, Department of Pediatrics, Aarhus University Hospital; P. Stoustrup, Associate Professor, DDS, PhD, Section of Orthodontics, Aarhus University; L.H. Matzen, DDS, PhD, Associate Professor, Section of Oral Radiology, Department of Dentistry and Oral Health, Aarhus University; V. Rypdal, MD, Department of Pediatrics, University Hospital of North Norway, and Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway; E. Nordal, MD, PhD, Department of Pediatrics, University Hospital of North Norway, and Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway; P. Frid, DDS, Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, and Department of Otorhinolaryngology and Department and Division of Oral and Maxillofacial Surgery, University Hospital North Norway and Public Dental Service Competence Center of North Norway; E.D. Arnstad, MD, Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, NTNU, and Department of Pediatrics, Levanger Hospital, Nord-Trøndelag Hospital Trust; M. Rygg, MD, Professor, PhD, Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, NTNU, and Department of Pediatrics, St. Olavs Hospital; O. Thorarensen, DDS, Department of Oral and Craniomaxillofacial Surgery, St. Olavs Hospital; M. Ekelund, MD, Department of Pediatrics, Ryhov County Hospital, and Department of Women’s and Children’s Health, Uppsala University; L. Berntson, MD, PhD, Department of Women’s and Children’s Health, Uppsala University; A. Fasth, MD, PhD, Professor, Department of Pediatrics, Sahlgrenska Academy, University of Gothenburg; H. Nilsson, DDS, PhD, Dr. Odont, Department of Oral and Maxillofacial Surgery/Stomatognathic Physiology, The Institute for Postgraduate Dental Education; S. Peltoniemi, MD, Hospital for Children and Adolescents, University of Helsinki; K. Aalto, MD, PhD, Hospital for Children and Adolescents, University of Helsinki; S. Arte, DDS, PhD, Orthodontics, Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital; P. Toftedal, MD, PhD, Department of Pediatrics, Copenhagen University Hospital; S. Nielsen, MD, Department of Pediatrics, Copenhagen University Hospital; S. Kreiborg, Professor, DDS, PhD, Dr. Odont, Department of Pediatric Dentistry and Clinical Genetics, University of Copenhagen; T. Herlin, Professor, MD, DMSc, Department of Pediatrics, Aarhus University Hospital; T.K. Pedersen, Professor, DDS, PhD, Section of Orthodontics, Aarhus University, and Department of Oral and Maxillofacial Surgery, Aarhus University Hospital. Address correspondence to Dr. M. Glerup, Department of Pediatrics, Aarhus University Hospital, Skejby, Palle Juul-Jensens Blvd. 99, 8200 Aarhus N, Denmark. E-mail: miagleru@rm.dk. Accepted for publication September 3, 2019.

From the Department of Pediatrics, Aarhus University Hospital; Section of Orthodontics, Aarhus University; Section of Oral Radiology, Department of Dentistry and Oral Health, Aarhus University, Aarhus, Denmark; Department of Pediatrics, University Hospital of North Norway, Tromsø; Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø; Department of Otorhinolaryngology and Department and Division of Oral and Maxillofacial Surgery, University Hospital North Norway and Public Dental Service Competence Center of North Norway, Tromsø; Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology (NTNU), Trondheim; Department of Pediatrics, Levanger Hospital, Nord-Trøndelag Hospital Trust, Levanger; Department of Pediatrics, St. Olavs Hospital, Trondheim; Department of Oral and Craniomaxillofacial Surgery, St. Olavs Hospital, Trondheim, Norway; Department of Pediatrics, Ryhov County Hospital, Jönköping; Department of Women’s and Children’s Health, Uppsala University, Uppsala; Department of Pediatrics, Sahlgrenska Academy, University of Gothenburg, Gothenburg; Department of Oral and Maxillofacial Surgery/Stomatognathic Physiology, The Institute for Postgraduate Dental Education, Jönköping, Sweden; Hospital for Children and Adolescents, University of Helsinki, Helsinki; Orthodontics, Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital, Helsinki, Finland; Department of Pediatrics, Copenhagen University Hospital, Copenhagen; Department of Pediatric Dentistry and Clinical Genetics, University of Copenhagen, Copenhagen; Department of Oral and Maxillofacial Surgery, Aarhus University Hospital, Aarhus, Denmark. M. Glerup, MD, Department of Pediatrics, Aarhus University Hospital; P. Stoustrup, Associate Professor, DDS, PhD, Section of Orthodontics, Aarhus University; L.H. Matzen, DDS, PhD, Associate Professor, Section of Oral Radiology, Department of Dentistry and Oral Health, Aarhus University; V. Rypdal, MD, Department of Pediatrics, University Hospital of North Norway, and Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway; E. Nordal, MD, PhD, Department of Pediatrics, University Hospital of North Norway, and Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway; P. Frid, DDS, Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, and Department of Otorhinolaryngology and Department and Division of Oral and Maxillofacial Surgery, University Hospital North Norway and Public Dental Service Competence Center of North Norway; E.D. Arnstad, MD, Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, NTNU, and Department of Pediatrics, Levanger Hospital, Nord-Trøndelag Hospital Trust; M. Rygg, MD, Professor, PhD, Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, NTNU, and Department of Pediatrics, St. Olavs Hospital; O. Thorarensen, DDS, Department of Oral and Craniomaxillofacial Surgery, St. Olavs Hospital; M. Ekelund, MD, Department of Pediatrics, Ryhov County Hospital, and Department of Women’s and Children’s Health, Uppsala University; L. Berntson, MD, PhD, Department of Women’s and Children’s Health, Uppsala University; A. Fasth, MD, PhD, Professor, Department of Pediatrics, Sahlgrenska Academy, University of Gothenburg; H. Nilsson, DDS, PhD, Dr. Odont, Department of Oral and Maxillofacial Surgery/Stomatognathic Physiology, The Institute for Postgraduate Dental Education; S. Peltoniemi, MD, Hospital for Children and Adolescents, University of Helsinki; K. Aalto, MD, PhD, Hospital for Children and Adolescents, University of Helsinki; S. Arte, DDS, PhD, Orthodontics, Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital; P. Toftedal, MD, PhD, Department of Pediatrics, Copenhagen University Hospital; S. Nielsen, MD, Department of Pediatrics, Copenhagen University Hospital; S. Kreiborg, Professor, DDS, PhD, Dr. Odont, Department of Pediatric Dentistry and Clinical Genetics, University of Copenhagen; T. Herlin, Professor, MD, DMSc, Department of Pediatrics, Aarhus University Hospital; T.K. Pedersen, Professor, DDS, PhD, Section of Orthodontics, Aarhus University, and Department of Oral and Maxillofacial Surgery, Aarhus University Hospital. Address correspondence to Dr. M. Glerup, Department of Pediatrics, Aarhus University Hospital, Skejby, Palle Juul-Jensens Blvd. 99, 8200 Aarhus N, Denmark. E-mail: miagleru@rm.dk. Accepted for publication September 3, 2019.

From the Department of Pediatrics, Aarhus University Hospital; Section of Orthodontics, Aarhus University; Section of Oral Radiology, Department of Dentistry and Oral Health, Aarhus University, Aarhus, Denmark; Department of Pediatrics, University Hospital of North Norway, Tromsø; Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø; Department of Otorhinolaryngology and Department and Division of Oral and Maxillofacial Surgery, University Hospital North Norway and Public Dental Service Competence Center of North Norway, Tromsø; Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology (NTNU), Trondheim; Department of Pediatrics, Levanger Hospital, Nord-Trøndelag Hospital Trust, Levanger; Department of Pediatrics, St. Olavs Hospital, Trondheim; Department of Oral and Craniomaxillofacial Surgery, St. Olavs Hospital, Trondheim, Norway; Department of Pediatrics, Ryhov County Hospital, Jönköping; Department of Women’s and Children’s Health, Uppsala University, Uppsala; Department of Pediatrics, Sahlgrenska Academy, University of Gothenburg, Gothenburg; Department of Oral and Maxillofacial Surgery/Stomatognathic Physiology, The Institute for Postgraduate Dental Education, Jönköping, Sweden; Hospital for Children and Adolescents, University of Helsinki, Helsinki; Orthodontics, Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital, Helsinki, Finland; Department of Pediatrics, Copenhagen University Hospital, Copenhagen; Department of Pediatric Dentistry and Clinical Genetics, University of Copenhagen, Copenhagen; Department of Oral and Maxillofacial Surgery, Aarhus University Hospital, Aarhus, Denmark. M. Glerup, MD, Department of Pediatrics, Aarhus University Hospital; P. Stoustrup, Associate Professor, DDS, PhD, Section of Orthodontics, Aarhus University; L.H. Matzen, DDS, PhD, Associate Professor, Section of Oral Radiology, Department of Dentistry and Oral Health, Aarhus University; V. Rypdal, MD, Department of Pediatrics, University Hospital of North Norway, and Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway; E. Nordal, MD, PhD, Department of Pediatrics, University Hospital of North Norway, and Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway; P. Frid, DDS, Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, and Department of Otorhinolaryngology and Department and Division of Oral and Maxillofacial Surgery, University Hospital North Norway and Public Dental Service Competence Center of North Norway; E.D. Arnstad, MD, Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, NTNU, and Department of Pediatrics, Levanger Hospital, Nord-Trøndelag Hospital Trust; M. Rygg, MD, Professor, PhD, Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, NTNU, and Department of Pediatrics, St. Olavs Hospital; O. Thorarensen, DDS, Department of Oral and Craniomaxillofacial Surgery, St. Olavs Hospital; M. Ekelund, MD, Department of Pediatrics, Ryhov County Hospital, and Department of Women’s and Children’s Health, Uppsala University; L. Berntson, MD, PhD, Department of Women’s and Children’s Health, Uppsala University; A. Fasth, MD, PhD, Professor, Department of Pediatrics, Sahlgrenska Academy, University of Gothenburg; H. Nilsson, DDS, PhD, Dr. Odont, Department of Oral and Maxillofacial Surgery/Stomatognathic Physiology, The Institute for Postgraduate Dental Education; S. Peltoniemi, MD, Hospital for Children and Adolescents, University of Helsinki; K. Aalto, MD, PhD, Hospital for Children and Adolescents, University of Helsinki; S. Arte, DDS, PhD, Orthodontics, Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital; P. Toftedal, MD, PhD, Department of Pediatrics, Copenhagen University Hospital; S. Nielsen, MD, Department of Pediatrics, Copenhagen University Hospital; S. Kreiborg, Professor, DDS, PhD, Dr. Odont, Department of Pediatric Dentistry and Clinical Genetics, University of Copenhagen; T. Herlin, Professor, MD, DMSc, Department of Pediatrics, Aarhus University Hospital; T.K. Pedersen, Professor, DDS, PhD, Section of Orthodontics, Aarhus University, and Department of Oral and Maxillofacial Surgery, Aarhus University Hospital. Address correspondence to Dr. M. Glerup, Department of Pediatrics, Aarhus University Hospital, Skejby, Palle Juul-Jensens Blvd. 99, 8200 Aarhus N, Denmark. E-mail: miagleru@rm.dk. Accepted for publication September 3, 2019.