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Research ArticleAccepted Article

In Psoriatic Arthritis fatigue is driven by inflammation, disease duration, and chronic pain: An observational DANBIO registry study

Marie Skougaard, Tanja Schjødt Jørgensen, Signe Rifbjerg-Madsen, Laura C. Coates, Alexander Egeberg, Kirstine Amris, Lene Dreyer, Pil Højgaard, Jørgen Guldberg-Møller, Joseph F. Merola, Peder Frederiksen, Henrik Gudbergsen and Lars Erik Kristensen
The Journal of Rheumatology July 2019, jrheum.181412; DOI: https://doi.org/10.3899/jrheum.181412
Marie Skougaard
From The Parker Institute, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark; Department of Rheumatology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom; Department of Dermatology and Allergy, Copenhagen University Hospital Gentofte and Herlev, Gentofte, Denmark; Departments of Clinical Medicine and Rheumatology, Aalborg University and Aalborg University Hospital, Aalborg, Denmark; The DANBIO Registry, Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet, Glostrup, Denmark; Center for Rheumatology and Spine Diseases, Copenhagen University Hospital Gentofte and Herlev, Gentofte, Denmark; Department of Dermatology and Department of Medicine, Division of Rheumatology, Brigham and Women’s Hospital, Harvard Medical School, Boston, USA. This work was supported by a core grant from the Oak Foundation [OCAY-13-309]
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Tanja Schjødt Jørgensen
From The Parker Institute, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark; Department of Rheumatology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom; Department of Dermatology and Allergy, Copenhagen University Hospital Gentofte and Herlev, Gentofte, Denmark; Departments of Clinical Medicine and Rheumatology, Aalborg University and Aalborg University Hospital, Aalborg, Denmark; The DANBIO Registry, Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet, Glostrup, Denmark; Center for Rheumatology and Spine Diseases, Copenhagen University Hospital Gentofte and Herlev, Gentofte, Denmark; Department of Dermatology and Department of Medicine, Division of Rheumatology, Brigham and Women’s Hospital, Harvard Medical School, Boston, USA. This work was supported by a core grant from the Oak Foundation [OCAY-13-309]
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Signe Rifbjerg-Madsen
From The Parker Institute, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark; Department of Rheumatology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom; Department of Dermatology and Allergy, Copenhagen University Hospital Gentofte and Herlev, Gentofte, Denmark; Departments of Clinical Medicine and Rheumatology, Aalborg University and Aalborg University Hospital, Aalborg, Denmark; The DANBIO Registry, Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet, Glostrup, Denmark; Center for Rheumatology and Spine Diseases, Copenhagen University Hospital Gentofte and Herlev, Gentofte, Denmark; Department of Dermatology and Department of Medicine, Division of Rheumatology, Brigham and Women’s Hospital, Harvard Medical School, Boston, USA. This work was supported by a core grant from the Oak Foundation [OCAY-13-309]
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Laura C. Coates
From The Parker Institute, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark; Department of Rheumatology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom; Department of Dermatology and Allergy, Copenhagen University Hospital Gentofte and Herlev, Gentofte, Denmark; Departments of Clinical Medicine and Rheumatology, Aalborg University and Aalborg University Hospital, Aalborg, Denmark; The DANBIO Registry, Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet, Glostrup, Denmark; Center for Rheumatology and Spine Diseases, Copenhagen University Hospital Gentofte and Herlev, Gentofte, Denmark; Department of Dermatology and Department of Medicine, Division of Rheumatology, Brigham and Women’s Hospital, Harvard Medical School, Boston, USA. This work was supported by a core grant from the Oak Foundation [OCAY-13-309]
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Alexander Egeberg
From The Parker Institute, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark; Department of Rheumatology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom; Department of Dermatology and Allergy, Copenhagen University Hospital Gentofte and Herlev, Gentofte, Denmark; Departments of Clinical Medicine and Rheumatology, Aalborg University and Aalborg University Hospital, Aalborg, Denmark; The DANBIO Registry, Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet, Glostrup, Denmark; Center for Rheumatology and Spine Diseases, Copenhagen University Hospital Gentofte and Herlev, Gentofte, Denmark; Department of Dermatology and Department of Medicine, Division of Rheumatology, Brigham and Women’s Hospital, Harvard Medical School, Boston, USA. This work was supported by a core grant from the Oak Foundation [OCAY-13-309]
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Kirstine Amris
From The Parker Institute, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark; Department of Rheumatology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom; Department of Dermatology and Allergy, Copenhagen University Hospital Gentofte and Herlev, Gentofte, Denmark; Departments of Clinical Medicine and Rheumatology, Aalborg University and Aalborg University Hospital, Aalborg, Denmark; The DANBIO Registry, Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet, Glostrup, Denmark; Center for Rheumatology and Spine Diseases, Copenhagen University Hospital Gentofte and Herlev, Gentofte, Denmark; Department of Dermatology and Department of Medicine, Division of Rheumatology, Brigham and Women’s Hospital, Harvard Medical School, Boston, USA. This work was supported by a core grant from the Oak Foundation [OCAY-13-309]
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Lene Dreyer
From The Parker Institute, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark; Department of Rheumatology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom; Department of Dermatology and Allergy, Copenhagen University Hospital Gentofte and Herlev, Gentofte, Denmark; Departments of Clinical Medicine and Rheumatology, Aalborg University and Aalborg University Hospital, Aalborg, Denmark; The DANBIO Registry, Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet, Glostrup, Denmark; Center for Rheumatology and Spine Diseases, Copenhagen University Hospital Gentofte and Herlev, Gentofte, Denmark; Department of Dermatology and Department of Medicine, Division of Rheumatology, Brigham and Women’s Hospital, Harvard Medical School, Boston, USA. This work was supported by a core grant from the Oak Foundation [OCAY-13-309]
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Pil Højgaard
From The Parker Institute, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark; Department of Rheumatology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom; Department of Dermatology and Allergy, Copenhagen University Hospital Gentofte and Herlev, Gentofte, Denmark; Departments of Clinical Medicine and Rheumatology, Aalborg University and Aalborg University Hospital, Aalborg, Denmark; The DANBIO Registry, Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet, Glostrup, Denmark; Center for Rheumatology and Spine Diseases, Copenhagen University Hospital Gentofte and Herlev, Gentofte, Denmark; Department of Dermatology and Department of Medicine, Division of Rheumatology, Brigham and Women’s Hospital, Harvard Medical School, Boston, USA. This work was supported by a core grant from the Oak Foundation [OCAY-13-309]
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Jørgen Guldberg-Møller
From The Parker Institute, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark; Department of Rheumatology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom; Department of Dermatology and Allergy, Copenhagen University Hospital Gentofte and Herlev, Gentofte, Denmark; Departments of Clinical Medicine and Rheumatology, Aalborg University and Aalborg University Hospital, Aalborg, Denmark; The DANBIO Registry, Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet, Glostrup, Denmark; Center for Rheumatology and Spine Diseases, Copenhagen University Hospital Gentofte and Herlev, Gentofte, Denmark; Department of Dermatology and Department of Medicine, Division of Rheumatology, Brigham and Women’s Hospital, Harvard Medical School, Boston, USA. This work was supported by a core grant from the Oak Foundation [OCAY-13-309]
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Joseph F. Merola
From The Parker Institute, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark; Department of Rheumatology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom; Department of Dermatology and Allergy, Copenhagen University Hospital Gentofte and Herlev, Gentofte, Denmark; Departments of Clinical Medicine and Rheumatology, Aalborg University and Aalborg University Hospital, Aalborg, Denmark; The DANBIO Registry, Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet, Glostrup, Denmark; Center for Rheumatology and Spine Diseases, Copenhagen University Hospital Gentofte and Herlev, Gentofte, Denmark; Department of Dermatology and Department of Medicine, Division of Rheumatology, Brigham and Women’s Hospital, Harvard Medical School, Boston, USA. This work was supported by a core grant from the Oak Foundation [OCAY-13-309]
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Peder Frederiksen
From The Parker Institute, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark; Department of Rheumatology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom; Department of Dermatology and Allergy, Copenhagen University Hospital Gentofte and Herlev, Gentofte, Denmark; Departments of Clinical Medicine and Rheumatology, Aalborg University and Aalborg University Hospital, Aalborg, Denmark; The DANBIO Registry, Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet, Glostrup, Denmark; Center for Rheumatology and Spine Diseases, Copenhagen University Hospital Gentofte and Herlev, Gentofte, Denmark; Department of Dermatology and Department of Medicine, Division of Rheumatology, Brigham and Women’s Hospital, Harvard Medical School, Boston, USA. This work was supported by a core grant from the Oak Foundation [OCAY-13-309]
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Henrik Gudbergsen
From The Parker Institute, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark; Department of Rheumatology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom; Department of Dermatology and Allergy, Copenhagen University Hospital Gentofte and Herlev, Gentofte, Denmark; Departments of Clinical Medicine and Rheumatology, Aalborg University and Aalborg University Hospital, Aalborg, Denmark; The DANBIO Registry, Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet, Glostrup, Denmark; Center for Rheumatology and Spine Diseases, Copenhagen University Hospital Gentofte and Herlev, Gentofte, Denmark; Department of Dermatology and Department of Medicine, Division of Rheumatology, Brigham and Women’s Hospital, Harvard Medical School, Boston, USA. This work was supported by a core grant from the Oak Foundation [OCAY-13-309]
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Lars Erik Kristensen
From The Parker Institute, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark; Department of Rheumatology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom; Department of Dermatology and Allergy, Copenhagen University Hospital Gentofte and Herlev, Gentofte, Denmark; Departments of Clinical Medicine and Rheumatology, Aalborg University and Aalborg University Hospital, Aalborg, Denmark; The DANBIO Registry, Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet, Glostrup, Denmark; Center for Rheumatology and Spine Diseases, Copenhagen University Hospital Gentofte and Herlev, Gentofte, Denmark; Department of Dermatology and Department of Medicine, Division of Rheumatology, Brigham and Women’s Hospital, Harvard Medical School, Boston, USA. This work was supported by a core grant from the Oak Foundation [OCAY-13-309]
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Accepted manuscript
In Psoriatic Arthritis fatigue is driven by inflammation, disease duration, and chronic pain: An observational DANBIO registry study
Marie Skougaard, Tanja Schjødt Jørgensen, Signe Rifbjerg-Madsen, Laura C. Coates, Alexander Egeberg, Kirstine Amris, Lene Dreyer, Pil Højgaard, Jørgen Guldberg-Møller, Joseph F. Merola, Peder Frederiksen, Henrik Gudbergsen, Lars Erik Kristensen
The Journal of Rheumatology Jul 2019, jrheum.181412; DOI: 10.3899/jrheum.181412

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Accepted manuscript
In Psoriatic Arthritis fatigue is driven by inflammation, disease duration, and chronic pain: An observational DANBIO registry study
Marie Skougaard, Tanja Schjødt Jørgensen, Signe Rifbjerg-Madsen, Laura C. Coates, Alexander Egeberg, Kirstine Amris, Lene Dreyer, Pil Højgaard, Jørgen Guldberg-Møller, Joseph F. Merola, Peder Frederiksen, Henrik Gudbergsen, Lars Erik Kristensen
The Journal of Rheumatology Jul 2019, jrheum.181412; DOI: 10.3899/jrheum.181412
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