Association of seventeen definitions of remission with functional status in a large clinical practice cohort of patients with rheumatoid arthritis

From the Rheumatology Department, Centro Hospitalar Universitário de Coimbra, Coimbra, Portugal; Rheumatology Department, Centro Hospitalar Universitário do Algarve, Faro, Portugal; Health Sciences Research Unit: Nursing (UICiSA:E), Escola Superior de Enfermagem de Coimbra, Coimbra, Portugal; Amsterdam Rheumatology Center, Amsterdam UMC, the Netherlands; Zuyderland Medical Center, Heerlen, the Netherlands; Hospital Universitario "Dr. José Eleuterio González" / Universidad Autónoma de Nuevo León, Monterrey, Mexico; University of Massachusetts Medical School, Rheumatology Centre, Massachusetts, USA; Dublin Academic Medical Centre, Dublin, Ireland; Centre for Rheumatic Diseases, Pune, India; Coimbra Institute for Clinical and Biomedical Research (iCBR) – Faculty of Medicine – University of Coimbra, Portugal; Centre for Rheumatology Research & MRC Centre for Neuromuscular Diseases, University College London, London, United Kingdom; Rheumatology Department, Northwick Park Hospital, London North West University Healthcare NHS Trust, London, United Kingdom. This study was conducted with the support of a research grant from the MERIT Foundation (http://www.meteorfoundation.com/). Pedro M. Machado was supported by the National Institute for Health Research (NIHR) University College London Hospitals (UCLH) Biomedical Research Centre (BRC). The views expressed are those of the authors and not necessarily those of the (UK) National Health Service (NHS), the NIHR or the (UK) Department of Health. Address correspondence to Pedro David Carvalho Orcid.org/0000-0001-8255-4274 Rheumatology Department, Centro Hospitalar Universitário do Algarve Rua Leão Penedo; 8000-386 Faro, Portugal

From the Rheumatology Department, Centro Hospitalar Universitário de Coimbra, Coimbra, Portugal; Rheumatology Department, Centro Hospitalar Universitário do Algarve, Faro, Portugal; Health Sciences Research Unit: Nursing (UICiSA:E), Escola Superior de Enfermagem de Coimbra, Coimbra, Portugal; Amsterdam Rheumatology Center, Amsterdam UMC, the Netherlands; Zuyderland Medical Center, Heerlen, the Netherlands; Hospital Universitario "Dr. José Eleuterio González" / Universidad Autónoma de Nuevo León, Monterrey, Mexico; University of Massachusetts Medical School, Rheumatology Centre, Massachusetts, USA; Dublin Academic Medical Centre, Dublin, Ireland; Centre for Rheumatic Diseases, Pune, India; Coimbra Institute for Clinical and Biomedical Research (iCBR) – Faculty of Medicine – University of Coimbra, Portugal; Centre for Rheumatology Research & MRC Centre for Neuromuscular Diseases, University College London, London, United Kingdom; Rheumatology Department, Northwick Park Hospital, London North West University Healthcare NHS Trust, London, United Kingdom. This study was conducted with the support of a research grant from the MERIT Foundation (http://www.meteorfoundation.com/). Pedro M. Machado was supported by the National Institute for Health Research (NIHR) University College London Hospitals (UCLH) Biomedical Research Centre (BRC). The views expressed are those of the authors and not necessarily those of the (UK) National Health Service (NHS), the NIHR or the (UK) Department of Health. Address correspondence to Pedro David Carvalho Orcid.org/0000-0001-8255-4274 Rheumatology Department, Centro Hospitalar Universitário do Algarve Rua Leão Penedo; 8000-386 Faro, Portugal

From the Rheumatology Department, Centro Hospitalar Universitário de Coimbra, Coimbra, Portugal; Rheumatology Department, Centro Hospitalar Universitário do Algarve, Faro, Portugal; Health Sciences Research Unit: Nursing (UICiSA:E), Escola Superior de Enfermagem de Coimbra, Coimbra, Portugal; Amsterdam Rheumatology Center, Amsterdam UMC, the Netherlands; Zuyderland Medical Center, Heerlen, the Netherlands; Hospital Universitario "Dr. José Eleuterio González" / Universidad Autónoma de Nuevo León, Monterrey, Mexico; University of Massachusetts Medical School, Rheumatology Centre, Massachusetts, USA; Dublin Academic Medical Centre, Dublin, Ireland; Centre for Rheumatic Diseases, Pune, India; Coimbra Institute for Clinical and Biomedical Research (iCBR) – Faculty of Medicine – University of Coimbra, Portugal; Centre for Rheumatology Research & MRC Centre for Neuromuscular Diseases, University College London, London, United Kingdom; Rheumatology Department, Northwick Park Hospital, London North West University Healthcare NHS Trust, London, United Kingdom. This study was conducted with the support of a research grant from the MERIT Foundation (http://www.meteorfoundation.com/). Pedro M. Machado was supported by the National Institute for Health Research (NIHR) University College London Hospitals (UCLH) Biomedical Research Centre (BRC). The views expressed are those of the authors and not necessarily those of the (UK) National Health Service (NHS), the NIHR or the (UK) Department of Health. Address correspondence to Pedro David Carvalho Orcid.org/0000-0001-8255-4274 Rheumatology Department, Centro Hospitalar Universitário do Algarve Rua Leão Penedo; 8000-386 Faro, Portugal

From the Rheumatology Department, Centro Hospitalar Universitário de Coimbra, Coimbra, Portugal; Rheumatology Department, Centro Hospitalar Universitário do Algarve, Faro, Portugal; Health Sciences Research Unit: Nursing (UICiSA:E), Escola Superior de Enfermagem de Coimbra, Coimbra, Portugal; Amsterdam Rheumatology Center, Amsterdam UMC, the Netherlands; Zuyderland Medical Center, Heerlen, the Netherlands; Hospital Universitario "Dr. José Eleuterio González" / Universidad Autónoma de Nuevo León, Monterrey, Mexico; University of Massachusetts Medical School, Rheumatology Centre, Massachusetts, USA; Dublin Academic Medical Centre, Dublin, Ireland; Centre for Rheumatic Diseases, Pune, India; Coimbra Institute for Clinical and Biomedical Research (iCBR) – Faculty of Medicine – University of Coimbra, Portugal; Centre for Rheumatology Research & MRC Centre for Neuromuscular Diseases, University College London, London, United Kingdom; Rheumatology Department, Northwick Park Hospital, London North West University Healthcare NHS Trust, London, United Kingdom. This study was conducted with the support of a research grant from the MERIT Foundation (http://www.meteorfoundation.com/). Pedro M. Machado was supported by the National Institute for Health Research (NIHR) University College London Hospitals (UCLH) Biomedical Research Centre (BRC). The views expressed are those of the authors and not necessarily those of the (UK) National Health Service (NHS), the NIHR or the (UK) Department of Health. Address correspondence to Pedro David Carvalho Orcid.org/0000-0001-8255-4274 Rheumatology Department, Centro Hospitalar Universitário do Algarve Rua Leão Penedo; 8000-386 Faro, Portugal

From the Rheumatology Department, Centro Hospitalar Universitário de Coimbra, Coimbra, Portugal; Rheumatology Department, Centro Hospitalar Universitário do Algarve, Faro, Portugal; Health Sciences Research Unit: Nursing (UICiSA:E), Escola Superior de Enfermagem de Coimbra, Coimbra, Portugal; Amsterdam Rheumatology Center, Amsterdam UMC, the Netherlands; Zuyderland Medical Center, Heerlen, the Netherlands; Hospital Universitario "Dr. José Eleuterio González" / Universidad Autónoma de Nuevo León, Monterrey, Mexico; University of Massachusetts Medical School, Rheumatology Centre, Massachusetts, USA; Dublin Academic Medical Centre, Dublin, Ireland; Centre for Rheumatic Diseases, Pune, India; Coimbra Institute for Clinical and Biomedical Research (iCBR) – Faculty of Medicine – University of Coimbra, Portugal; Centre for Rheumatology Research & MRC Centre for Neuromuscular Diseases, University College London, London, United Kingdom; Rheumatology Department, Northwick Park Hospital, London North West University Healthcare NHS Trust, London, United Kingdom. This study was conducted with the support of a research grant from the MERIT Foundation (http://www.meteorfoundation.com/). Pedro M. Machado was supported by the National Institute for Health Research (NIHR) University College London Hospitals (UCLH) Biomedical Research Centre (BRC). The views expressed are those of the authors and not necessarily those of the (UK) National Health Service (NHS), the NIHR or the (UK) Department of Health. Address correspondence to Pedro David Carvalho Orcid.org/0000-0001-8255-4274 Rheumatology Department, Centro Hospitalar Universitário do Algarve Rua Leão Penedo; 8000-386 Faro, Portugal

From the Rheumatology Department, Centro Hospitalar Universitário de Coimbra, Coimbra, Portugal; Rheumatology Department, Centro Hospitalar Universitário do Algarve, Faro, Portugal; Health Sciences Research Unit: Nursing (UICiSA:E), Escola Superior de Enfermagem de Coimbra, Coimbra, Portugal; Amsterdam Rheumatology Center, Amsterdam UMC, the Netherlands; Zuyderland Medical Center, Heerlen, the Netherlands; Hospital Universitario "Dr. José Eleuterio González" / Universidad Autónoma de Nuevo León, Monterrey, Mexico; University of Massachusetts Medical School, Rheumatology Centre, Massachusetts, USA; Dublin Academic Medical Centre, Dublin, Ireland; Centre for Rheumatic Diseases, Pune, India; Coimbra Institute for Clinical and Biomedical Research (iCBR) – Faculty of Medicine – University of Coimbra, Portugal; Centre for Rheumatology Research & MRC Centre for Neuromuscular Diseases, University College London, London, United Kingdom; Rheumatology Department, Northwick Park Hospital, London North West University Healthcare NHS Trust, London, United Kingdom. This study was conducted with the support of a research grant from the MERIT Foundation (http://www.meteorfoundation.com/). Pedro M. Machado was supported by the National Institute for Health Research (NIHR) University College London Hospitals (UCLH) Biomedical Research Centre (BRC). The views expressed are those of the authors and not necessarily those of the (UK) National Health Service (NHS), the NIHR or the (UK) Department of Health. Address correspondence to Pedro David Carvalho Orcid.org/0000-0001-8255-4274 Rheumatology Department, Centro Hospitalar Universitário do Algarve Rua Leão Penedo; 8000-386 Faro, Portugal

From the Rheumatology Department, Centro Hospitalar Universitário de Coimbra, Coimbra, Portugal; Rheumatology Department, Centro Hospitalar Universitário do Algarve, Faro, Portugal; Health Sciences Research Unit: Nursing (UICiSA:E), Escola Superior de Enfermagem de Coimbra, Coimbra, Portugal; Amsterdam Rheumatology Center, Amsterdam UMC, the Netherlands; Zuyderland Medical Center, Heerlen, the Netherlands; Hospital Universitario "Dr. José Eleuterio González" / Universidad Autónoma de Nuevo León, Monterrey, Mexico; University of Massachusetts Medical School, Rheumatology Centre, Massachusetts, USA; Dublin Academic Medical Centre, Dublin, Ireland; Centre for Rheumatic Diseases, Pune, India; Coimbra Institute for Clinical and Biomedical Research (iCBR) – Faculty of Medicine – University of Coimbra, Portugal; Centre for Rheumatology Research & MRC Centre for Neuromuscular Diseases, University College London, London, United Kingdom; Rheumatology Department, Northwick Park Hospital, London North West University Healthcare NHS Trust, London, United Kingdom. This study was conducted with the support of a research grant from the MERIT Foundation (http://www.meteorfoundation.com/). Pedro M. Machado was supported by the National Institute for Health Research (NIHR) University College London Hospitals (UCLH) Biomedical Research Centre (BRC). The views expressed are those of the authors and not necessarily those of the (UK) National Health Service (NHS), the NIHR or the (UK) Department of Health. Address correspondence to Pedro David Carvalho Orcid.org/0000-0001-8255-4274 Rheumatology Department, Centro Hospitalar Universitário do Algarve Rua Leão Penedo; 8000-386 Faro, Portugal

From the Rheumatology Department, Centro Hospitalar Universitário de Coimbra, Coimbra, Portugal; Rheumatology Department, Centro Hospitalar Universitário do Algarve, Faro, Portugal; Health Sciences Research Unit: Nursing (UICiSA:E), Escola Superior de Enfermagem de Coimbra, Coimbra, Portugal; Amsterdam Rheumatology Center, Amsterdam UMC, the Netherlands; Zuyderland Medical Center, Heerlen, the Netherlands; Hospital Universitario "Dr. José Eleuterio González" / Universidad Autónoma de Nuevo León, Monterrey, Mexico; University of Massachusetts Medical School, Rheumatology Centre, Massachusetts, USA; Dublin Academic Medical Centre, Dublin, Ireland; Centre for Rheumatic Diseases, Pune, India; Coimbra Institute for Clinical and Biomedical Research (iCBR) – Faculty of Medicine – University of Coimbra, Portugal; Centre for Rheumatology Research & MRC Centre for Neuromuscular Diseases, University College London, London, United Kingdom; Rheumatology Department, Northwick Park Hospital, London North West University Healthcare NHS Trust, London, United Kingdom. This study was conducted with the support of a research grant from the MERIT Foundation (http://www.meteorfoundation.com/). Pedro M. Machado was supported by the National Institute for Health Research (NIHR) University College London Hospitals (UCLH) Biomedical Research Centre (BRC). The views expressed are those of the authors and not necessarily those of the (UK) National Health Service (NHS), the NIHR or the (UK) Department of Health. Address correspondence to Pedro David Carvalho Orcid.org/0000-0001-8255-4274 Rheumatology Department, Centro Hospitalar Universitário do Algarve Rua Leão Penedo; 8000-386 Faro, Portugal

From the Rheumatology Department, Centro Hospitalar Universitário de Coimbra, Coimbra, Portugal; Rheumatology Department, Centro Hospitalar Universitário do Algarve, Faro, Portugal; Health Sciences Research Unit: Nursing (UICiSA:E), Escola Superior de Enfermagem de Coimbra, Coimbra, Portugal; Amsterdam Rheumatology Center, Amsterdam UMC, the Netherlands; Zuyderland Medical Center, Heerlen, the Netherlands; Hospital Universitario "Dr. José Eleuterio González" / Universidad Autónoma de Nuevo León, Monterrey, Mexico; University of Massachusetts Medical School, Rheumatology Centre, Massachusetts, USA; Dublin Academic Medical Centre, Dublin, Ireland; Centre for Rheumatic Diseases, Pune, India; Coimbra Institute for Clinical and Biomedical Research (iCBR) – Faculty of Medicine – University of Coimbra, Portugal; Centre for Rheumatology Research & MRC Centre for Neuromuscular Diseases, University College London, London, United Kingdom; Rheumatology Department, Northwick Park Hospital, London North West University Healthcare NHS Trust, London, United Kingdom. This study was conducted with the support of a research grant from the MERIT Foundation (http://www.meteorfoundation.com/). Pedro M. Machado was supported by the National Institute for Health Research (NIHR) University College London Hospitals (UCLH) Biomedical Research Centre (BRC). The views expressed are those of the authors and not necessarily those of the (UK) National Health Service (NHS), the NIHR or the (UK) Department of Health. Address correspondence to Pedro David Carvalho Orcid.org/0000-0001-8255-4274 Rheumatology Department, Centro Hospitalar Universitário do Algarve Rua Leão Penedo; 8000-386 Faro, Portugal