Safety and efficacy of intravenous golimumab in adults with ankylosing spondylitis: Results through 1 year of the GO-ALIVE study

From the University of Texas McGovern Medical School, Houston, TX, USA; Oregon Health & Science University, Portland, OR, USA; Arizona Arthritis and Rheumatology Associates, Phoenix, AZ, USA; AMED Medical Center, Warsaw, Poland; Janssen Research & Development, LLC, Spring House, PA, USA; University of Pennsylvania, Philadelphia, PA, USA. Funding: This study was funded by Janssen Research & Development, LLC. Drs. Caldron, and Dudek served as trial investigators for Janssen; Dr. Reveille has received consultancies from Eli Lilly, Janssen, Novartis, Pfizer, and UCB and has served as a trial investigator for Janssen and Eli Lilly; Dr. Deodhar has received consultancies, speaking fees, and/or honoraria from AbbVie, BMS, Eli Lilly, Janssen, Novartis, Pfizer, and UCB; Drs. Harrison, Hsia, Kim, Lo, and Leu are or were employees of Janssen Research & Development, LLC at the time this work was performed, and own stock in Johnson & Johnson, of which Janssen Research & Development, LLC, is a wholly owned subsidiary. Address correspondence to: Elizabeth C Hsia, MD, MSCE Janssen Research & Development, LLC. 1400 McKean Rd PO Box 776 Spring House, PA 19477, E-mail: ehsia@its.jnj.com

From the University of Texas McGovern Medical School, Houston, TX, USA; Oregon Health & Science University, Portland, OR, USA; Arizona Arthritis and Rheumatology Associates, Phoenix, AZ, USA; AMED Medical Center, Warsaw, Poland; Janssen Research & Development, LLC, Spring House, PA, USA; University of Pennsylvania, Philadelphia, PA, USA. Funding: This study was funded by Janssen Research & Development, LLC. Drs. Caldron, and Dudek served as trial investigators for Janssen; Dr. Reveille has received consultancies from Eli Lilly, Janssen, Novartis, Pfizer, and UCB and has served as a trial investigator for Janssen and Eli Lilly; Dr. Deodhar has received consultancies, speaking fees, and/or honoraria from AbbVie, BMS, Eli Lilly, Janssen, Novartis, Pfizer, and UCB; Drs. Harrison, Hsia, Kim, Lo, and Leu are or were employees of Janssen Research & Development, LLC at the time this work was performed, and own stock in Johnson & Johnson, of which Janssen Research & Development, LLC, is a wholly owned subsidiary. Address correspondence to: Elizabeth C Hsia, MD, MSCE Janssen Research & Development, LLC. 1400 McKean Rd PO Box 776 Spring House, PA 19477, E-mail: ehsia@its.jnj.com

From the University of Texas McGovern Medical School, Houston, TX, USA; Oregon Health & Science University, Portland, OR, USA; Arizona Arthritis and Rheumatology Associates, Phoenix, AZ, USA; AMED Medical Center, Warsaw, Poland; Janssen Research & Development, LLC, Spring House, PA, USA; University of Pennsylvania, Philadelphia, PA, USA. Funding: This study was funded by Janssen Research & Development, LLC. Drs. Caldron, and Dudek served as trial investigators for Janssen; Dr. Reveille has received consultancies from Eli Lilly, Janssen, Novartis, Pfizer, and UCB and has served as a trial investigator for Janssen and Eli Lilly; Dr. Deodhar has received consultancies, speaking fees, and/or honoraria from AbbVie, BMS, Eli Lilly, Janssen, Novartis, Pfizer, and UCB; Drs. Harrison, Hsia, Kim, Lo, and Leu are or were employees of Janssen Research & Development, LLC at the time this work was performed, and own stock in Johnson & Johnson, of which Janssen Research & Development, LLC, is a wholly owned subsidiary. Address correspondence to: Elizabeth C Hsia, MD, MSCE Janssen Research & Development, LLC. 1400 McKean Rd PO Box 776 Spring House, PA 19477, E-mail: ehsia@its.jnj.com

From the University of Texas McGovern Medical School, Houston, TX, USA; Oregon Health & Science University, Portland, OR, USA; Arizona Arthritis and Rheumatology Associates, Phoenix, AZ, USA; AMED Medical Center, Warsaw, Poland; Janssen Research & Development, LLC, Spring House, PA, USA; University of Pennsylvania, Philadelphia, PA, USA. Funding: This study was funded by Janssen Research & Development, LLC. Drs. Caldron, and Dudek served as trial investigators for Janssen; Dr. Reveille has received consultancies from Eli Lilly, Janssen, Novartis, Pfizer, and UCB and has served as a trial investigator for Janssen and Eli Lilly; Dr. Deodhar has received consultancies, speaking fees, and/or honoraria from AbbVie, BMS, Eli Lilly, Janssen, Novartis, Pfizer, and UCB; Drs. Harrison, Hsia, Kim, Lo, and Leu are or were employees of Janssen Research & Development, LLC at the time this work was performed, and own stock in Johnson & Johnson, of which Janssen Research & Development, LLC, is a wholly owned subsidiary. Address correspondence to: Elizabeth C Hsia, MD, MSCE Janssen Research & Development, LLC. 1400 McKean Rd PO Box 776 Spring House, PA 19477, E-mail: ehsia@its.jnj.com

From the University of Texas McGovern Medical School, Houston, TX, USA; Oregon Health & Science University, Portland, OR, USA; Arizona Arthritis and Rheumatology Associates, Phoenix, AZ, USA; AMED Medical Center, Warsaw, Poland; Janssen Research & Development, LLC, Spring House, PA, USA; University of Pennsylvania, Philadelphia, PA, USA. Funding: This study was funded by Janssen Research & Development, LLC. Drs. Caldron, and Dudek served as trial investigators for Janssen; Dr. Reveille has received consultancies from Eli Lilly, Janssen, Novartis, Pfizer, and UCB and has served as a trial investigator for Janssen and Eli Lilly; Dr. Deodhar has received consultancies, speaking fees, and/or honoraria from AbbVie, BMS, Eli Lilly, Janssen, Novartis, Pfizer, and UCB; Drs. Harrison, Hsia, Kim, Lo, and Leu are or were employees of Janssen Research & Development, LLC at the time this work was performed, and own stock in Johnson & Johnson, of which Janssen Research & Development, LLC, is a wholly owned subsidiary. Address correspondence to: Elizabeth C Hsia, MD, MSCE Janssen Research & Development, LLC. 1400 McKean Rd PO Box 776 Spring House, PA 19477, E-mail: ehsia@its.jnj.com

From the University of Texas McGovern Medical School, Houston, TX, USA; Oregon Health & Science University, Portland, OR, USA; Arizona Arthritis and Rheumatology Associates, Phoenix, AZ, USA; AMED Medical Center, Warsaw, Poland; Janssen Research & Development, LLC, Spring House, PA, USA; University of Pennsylvania, Philadelphia, PA, USA. Funding: This study was funded by Janssen Research & Development, LLC. Drs. Caldron, and Dudek served as trial investigators for Janssen; Dr. Reveille has received consultancies from Eli Lilly, Janssen, Novartis, Pfizer, and UCB and has served as a trial investigator for Janssen and Eli Lilly; Dr. Deodhar has received consultancies, speaking fees, and/or honoraria from AbbVie, BMS, Eli Lilly, Janssen, Novartis, Pfizer, and UCB; Drs. Harrison, Hsia, Kim, Lo, and Leu are or were employees of Janssen Research & Development, LLC at the time this work was performed, and own stock in Johnson & Johnson, of which Janssen Research & Development, LLC, is a wholly owned subsidiary. Address correspondence to: Elizabeth C Hsia, MD, MSCE Janssen Research & Development, LLC. 1400 McKean Rd PO Box 776 Spring House, PA 19477, E-mail: ehsia@its.jnj.com

From the University of Texas McGovern Medical School, Houston, TX, USA; Oregon Health & Science University, Portland, OR, USA; Arizona Arthritis and Rheumatology Associates, Phoenix, AZ, USA; AMED Medical Center, Warsaw, Poland; Janssen Research & Development, LLC, Spring House, PA, USA; University of Pennsylvania, Philadelphia, PA, USA. Funding: This study was funded by Janssen Research & Development, LLC. Drs. Caldron, and Dudek served as trial investigators for Janssen; Dr. Reveille has received consultancies from Eli Lilly, Janssen, Novartis, Pfizer, and UCB and has served as a trial investigator for Janssen and Eli Lilly; Dr. Deodhar has received consultancies, speaking fees, and/or honoraria from AbbVie, BMS, Eli Lilly, Janssen, Novartis, Pfizer, and UCB; Drs. Harrison, Hsia, Kim, Lo, and Leu are or were employees of Janssen Research & Development, LLC at the time this work was performed, and own stock in Johnson & Johnson, of which Janssen Research & Development, LLC, is a wholly owned subsidiary. Address correspondence to: Elizabeth C Hsia, MD, MSCE Janssen Research & Development, LLC. 1400 McKean Rd PO Box 776 Spring House, PA 19477, E-mail: ehsia@its.jnj.com

From the University of Texas McGovern Medical School, Houston, TX, USA; Oregon Health & Science University, Portland, OR, USA; Arizona Arthritis and Rheumatology Associates, Phoenix, AZ, USA; AMED Medical Center, Warsaw, Poland; Janssen Research & Development, LLC, Spring House, PA, USA; University of Pennsylvania, Philadelphia, PA, USA. Funding: This study was funded by Janssen Research & Development, LLC. Drs. Caldron, and Dudek served as trial investigators for Janssen; Dr. Reveille has received consultancies from Eli Lilly, Janssen, Novartis, Pfizer, and UCB and has served as a trial investigator for Janssen and Eli Lilly; Dr. Deodhar has received consultancies, speaking fees, and/or honoraria from AbbVie, BMS, Eli Lilly, Janssen, Novartis, Pfizer, and UCB; Drs. Harrison, Hsia, Kim, Lo, and Leu are or were employees of Janssen Research & Development, LLC at the time this work was performed, and own stock in Johnson & Johnson, of which Janssen Research & Development, LLC, is a wholly owned subsidiary. Address correspondence to: Elizabeth C Hsia, MD, MSCE Janssen Research & Development, LLC. 1400 McKean Rd PO Box 776 Spring House, PA 19477, E-mail: ehsia@its.jnj.com

From the University of Texas McGovern Medical School, Houston, TX, USA; Oregon Health & Science University, Portland, OR, USA; Arizona Arthritis and Rheumatology Associates, Phoenix, AZ, USA; AMED Medical Center, Warsaw, Poland; Janssen Research & Development, LLC, Spring House, PA, USA; University of Pennsylvania, Philadelphia, PA, USA. Funding: This study was funded by Janssen Research & Development, LLC. Drs. Caldron, and Dudek served as trial investigators for Janssen; Dr. Reveille has received consultancies from Eli Lilly, Janssen, Novartis, Pfizer, and UCB and has served as a trial investigator for Janssen and Eli Lilly; Dr. Deodhar has received consultancies, speaking fees, and/or honoraria from AbbVie, BMS, Eli Lilly, Janssen, Novartis, Pfizer, and UCB; Drs. Harrison, Hsia, Kim, Lo, and Leu are or were employees of Janssen Research & Development, LLC at the time this work was performed, and own stock in Johnson & Johnson, of which Janssen Research & Development, LLC, is a wholly owned subsidiary. Address correspondence to: Elizabeth C Hsia, MD, MSCE Janssen Research & Development, LLC. 1400 McKean Rd PO Box 776 Spring House, PA 19477, E-mail: ehsia@its.jnj.com