Research ArticleArticle
Novel Composite Radiographic Score for Longitudinal Observational Studies of Psoriatic Arthritis: A Proof-of-concept Study
William Tillett, Gavin Shaddick, Deepak Jadon, Graham Robinson, Eleanor Korendowych and Neil McHugh
The Journal of Rheumatology January 2016, jrheum.150114; DOI: https://doi.org/10.3899/jrheum.150114
William Tillett
From the Royal National Hospital for Rheumatic Diseases; Department of Mathematics, University of Bath; Department of Pharmacy and Pharmacology, University of Bath; Department of Radiology, Royal United Hospital, Bath, UK. Funded through an unrestricted grant from Abbvie Laboratories Ltd. W. Tillett, BSc, MBChB, PhD, MRCP, Royal National Hospital for Rheumatic Diseases; G. Shaddick, MSc, PhD, Department of Mathematics, University of Bath; D. Jadon, MBBCh, MRCP, Royal National Hospital for Rheumatic Diseases; G. Robinson, MBBS, FRCR, Department of Radiology, Royal United Hospital; E. Korendowych, PhD, MRCP, Royal National Hospital for Rheumatic Diseases; N. McHugh, MB, ChB, MD, FRCP, Department of Pharmacy and Pharmacology, University of Bath. Address correspondence to Dr. W. Tillett, Royal National Hospital for Rheumatic Diseases, Upper Borough Walls, Bath, BA11RL, UK. E-mail: w.tillett@nhs.net. Accepted for publication October 29, 2015.
Gavin Shaddick
From the Royal National Hospital for Rheumatic Diseases; Department of Mathematics, University of Bath; Department of Pharmacy and Pharmacology, University of Bath; Department of Radiology, Royal United Hospital, Bath, UK. Funded through an unrestricted grant from Abbvie Laboratories Ltd. W. Tillett, BSc, MBChB, PhD, MRCP, Royal National Hospital for Rheumatic Diseases; G. Shaddick, MSc, PhD, Department of Mathematics, University of Bath; D. Jadon, MBBCh, MRCP, Royal National Hospital for Rheumatic Diseases; G. Robinson, MBBS, FRCR, Department of Radiology, Royal United Hospital; E. Korendowych, PhD, MRCP, Royal National Hospital for Rheumatic Diseases; N. McHugh, MB, ChB, MD, FRCP, Department of Pharmacy and Pharmacology, University of Bath. Address correspondence to Dr. W. Tillett, Royal National Hospital for Rheumatic Diseases, Upper Borough Walls, Bath, BA11RL, UK. E-mail: w.tillett@nhs.net. Accepted for publication October 29, 2015.
Deepak Jadon
From the Royal National Hospital for Rheumatic Diseases; Department of Mathematics, University of Bath; Department of Pharmacy and Pharmacology, University of Bath; Department of Radiology, Royal United Hospital, Bath, UK. Funded through an unrestricted grant from Abbvie Laboratories Ltd. W. Tillett, BSc, MBChB, PhD, MRCP, Royal National Hospital for Rheumatic Diseases; G. Shaddick, MSc, PhD, Department of Mathematics, University of Bath; D. Jadon, MBBCh, MRCP, Royal National Hospital for Rheumatic Diseases; G. Robinson, MBBS, FRCR, Department of Radiology, Royal United Hospital; E. Korendowych, PhD, MRCP, Royal National Hospital for Rheumatic Diseases; N. McHugh, MB, ChB, MD, FRCP, Department of Pharmacy and Pharmacology, University of Bath. Address correspondence to Dr. W. Tillett, Royal National Hospital for Rheumatic Diseases, Upper Borough Walls, Bath, BA11RL, UK. E-mail: w.tillett@nhs.net. Accepted for publication October 29, 2015.
Graham Robinson
From the Royal National Hospital for Rheumatic Diseases; Department of Mathematics, University of Bath; Department of Pharmacy and Pharmacology, University of Bath; Department of Radiology, Royal United Hospital, Bath, UK. Funded through an unrestricted grant from Abbvie Laboratories Ltd. W. Tillett, BSc, MBChB, PhD, MRCP, Royal National Hospital for Rheumatic Diseases; G. Shaddick, MSc, PhD, Department of Mathematics, University of Bath; D. Jadon, MBBCh, MRCP, Royal National Hospital for Rheumatic Diseases; G. Robinson, MBBS, FRCR, Department of Radiology, Royal United Hospital; E. Korendowych, PhD, MRCP, Royal National Hospital for Rheumatic Diseases; N. McHugh, MB, ChB, MD, FRCP, Department of Pharmacy and Pharmacology, University of Bath. Address correspondence to Dr. W. Tillett, Royal National Hospital for Rheumatic Diseases, Upper Borough Walls, Bath, BA11RL, UK. E-mail: w.tillett@nhs.net. Accepted for publication October 29, 2015.
Eleanor Korendowych
From the Royal National Hospital for Rheumatic Diseases; Department of Mathematics, University of Bath; Department of Pharmacy and Pharmacology, University of Bath; Department of Radiology, Royal United Hospital, Bath, UK. Funded through an unrestricted grant from Abbvie Laboratories Ltd. W. Tillett, BSc, MBChB, PhD, MRCP, Royal National Hospital for Rheumatic Diseases; G. Shaddick, MSc, PhD, Department of Mathematics, University of Bath; D. Jadon, MBBCh, MRCP, Royal National Hospital for Rheumatic Diseases; G. Robinson, MBBS, FRCR, Department of Radiology, Royal United Hospital; E. Korendowych, PhD, MRCP, Royal National Hospital for Rheumatic Diseases; N. McHugh, MB, ChB, MD, FRCP, Department of Pharmacy and Pharmacology, University of Bath. Address correspondence to Dr. W. Tillett, Royal National Hospital for Rheumatic Diseases, Upper Borough Walls, Bath, BA11RL, UK. E-mail: w.tillett@nhs.net. Accepted for publication October 29, 2015.
Neil McHugh
From the Royal National Hospital for Rheumatic Diseases; Department of Mathematics, University of Bath; Department of Pharmacy and Pharmacology, University of Bath; Department of Radiology, Royal United Hospital, Bath, UK. Funded through an unrestricted grant from Abbvie Laboratories Ltd. W. Tillett, BSc, MBChB, PhD, MRCP, Royal National Hospital for Rheumatic Diseases; G. Shaddick, MSc, PhD, Department of Mathematics, University of Bath; D. Jadon, MBBCh, MRCP, Royal National Hospital for Rheumatic Diseases; G. Robinson, MBBS, FRCR, Department of Radiology, Royal United Hospital; E. Korendowych, PhD, MRCP, Royal National Hospital for Rheumatic Diseases; N. McHugh, MB, ChB, MD, FRCP, Department of Pharmacy and Pharmacology, University of Bath. Address correspondence to Dr. W. Tillett, Royal National Hospital for Rheumatic Diseases, Upper Borough Walls, Bath, BA11RL, UK. E-mail: w.tillett@nhs.net. Accepted for publication October 29, 2015.
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Abstract
Objective To devise a feasible composite radiographic score for use in observational studies of psoriatic arthritis (PsA).
Methods Radiographs from 50 patients with PsA were evaluated with the PsA-modified Sharp, Sharp/van der Heijde (SvdH), and Ratingen scores. Data reductions were made to devise a concise score.
Results The Reductive X-ray Score for Psoriatic Arthritis (ReXSPA) required the assessment of only 22 joints (117 points), including erosion, joint space narrowing, and osteoproliferation in the hands and feet. The ReXSPA accounted for 80% of change detected with the SvdH score.
Conclusion We report a proof-of-concept radiographic score for observational studies derived though data reduction.
In this issue
The Journal of Rheumatology
Vol. 51, Issue 4
1 Apr 2024
Novel Composite Radiographic Score for Longitudinal Observational Studies of Psoriatic Arthritis: A Proof-of-concept Study
William Tillett, Gavin Shaddick, Deepak Jadon, Graham Robinson, Eleanor Korendowych, Neil McHugh
The Journal of Rheumatology Jan 2016, jrheum.150114; DOI: 10.3899/jrheum.150114